JP2021519269A5 - - Google Patents

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Publication number
JP2021519269A5
JP2021519269A5 JP2020551327A JP2020551327A JP2021519269A5 JP 2021519269 A5 JP2021519269 A5 JP 2021519269A5 JP 2020551327 A JP2020551327 A JP 2020551327A JP 2020551327 A JP2020551327 A JP 2020551327A JP 2021519269 A5 JP2021519269 A5 JP 2021519269A5
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JP
Japan
Prior art keywords
oxide
alkyl
azaspiro
piperazine
carboxylate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020551327A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021519269A (ja
JP7497294B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/023916 external-priority patent/WO2019183636A1/en
Publication of JP2021519269A publication Critical patent/JP2021519269A/ja
Publication of JP2021519269A5 publication Critical patent/JP2021519269A5/ja
Priority to JP2023214561A priority Critical patent/JP2024037979A/ja
Application granted granted Critical
Publication of JP7497294B2 publication Critical patent/JP7497294B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020551327A 2018-03-23 2019-03-25 ピペラジンアザスピロ誘導体 Active JP7497294B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023214561A JP2024037979A (ja) 2018-03-23 2023-12-20 ピペラジンアザスピロ誘導体

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862647106P 2018-03-23 2018-03-23
US62/647,106 2018-03-23
PCT/US2019/023916 WO2019183636A1 (en) 2018-03-23 2019-03-25 Piperazine azaspiro derivaves

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023214561A Division JP2024037979A (ja) 2018-03-23 2023-12-20 ピペラジンアザスピロ誘導体

Publications (3)

Publication Number Publication Date
JP2021519269A JP2021519269A (ja) 2021-08-10
JP2021519269A5 true JP2021519269A5 (https=) 2022-03-31
JP7497294B2 JP7497294B2 (ja) 2024-06-10

Family

ID=66102243

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020551327A Active JP7497294B2 (ja) 2018-03-23 2019-03-25 ピペラジンアザスピロ誘導体
JP2023214561A Pending JP2024037979A (ja) 2018-03-23 2023-12-20 ピペラジンアザスピロ誘導体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023214561A Pending JP2024037979A (ja) 2018-03-23 2023-12-20 ピペラジンアザスピロ誘導体

Country Status (14)

Country Link
US (2) US11524954B2 (https=)
EP (2) EP4219464A1 (https=)
JP (2) JP7497294B2 (https=)
CN (1) CN112154145B (https=)
AR (1) AR115015A1 (https=)
CA (1) CA3094366A1 (https=)
DK (1) DK3768669T3 (https=)
ES (1) ES2942837T3 (https=)
FI (1) FI3768669T3 (https=)
HU (1) HUE061533T2 (https=)
PL (1) PL3768669T3 (https=)
PT (1) PT3768669T (https=)
TW (1) TWI801540B (https=)
WO (1) WO2019183636A1 (https=)

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PT3768669T (pt) * 2018-03-23 2023-04-24 Pfizer Derivados de piperazina azaspiro
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KR20210067005A (ko) * 2019-11-28 2021-06-08 제이투에이치바이오텍 (주) 에다라본 전구체 약물 화합물 및 이들의 신경퇴행성 또는 운동신경 질환의 치료 또는 개선을 위한 의약 용도
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JP7707176B2 (ja) * 2020-02-05 2025-07-14 ニューロクライン バイオサイエンシーズ，インコーポレイテッド ムスカリン性受容体４アンタゴニストおよび使用方法
CN119119063A (zh) 2021-05-12 2024-12-13 勃林格殷格翰国际有限公司 作为cGAS抑制剂的具有N-连接环状取代基的吡啶衍生物
WO2023010078A1 (en) * 2021-07-30 2023-02-02 Neurocrine Biosciences, Inc. Muscarinic receptor 4 antagonists and methods of use
CN120344513A (zh) * 2022-09-16 2025-07-18 赛尔维治疗有限责任公司 M4活化剂/调节剂及其用途
KR20250133755A (ko) * 2023-01-12 2025-09-08 세레벨 쎄라퓨틱스, 엘엘씨 M4 활성제/조절제로서의 스피로 유도체 및 이의 용도

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