JP2021517886A5 - - Google Patents
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- Publication number
- JP2021517886A5 JP2021517886A5 JP2020538940A JP2020538940A JP2021517886A5 JP 2021517886 A5 JP2021517886 A5 JP 2021517886A5 JP 2020538940 A JP2020538940 A JP 2020538940A JP 2020538940 A JP2020538940 A JP 2020538940A JP 2021517886 A5 JP2021517886 A5 JP 2021517886A5
- Authority
- JP
- Japan
- Prior art keywords
- oral cancer
- cancer cells
- pharmaceutical composition
- ginsenoside
- drug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 208000003445 Mouth Neoplasms Diseases 0.000 claims 8
- 208000012987 lip and oral cavity carcinoma Diseases 0.000 claims 8
- 239000008194 pharmaceutical composition Substances 0.000 claims 5
- 208000000102 Squamous Cell Carcinoma of Head and Neck Diseases 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 4
- 229940079593 drug Drugs 0.000 claims 4
- FVIZARNDLVOMSU-IRFFNABBSA-N ginsenoside C-K Chemical compound O([C@@](C)(CCC=C(C)C)[C@@H]1[C@@H]2[C@@]([C@@]3(CC[C@H]4C(C)(C)[C@@H](O)CC[C@]4(C)[C@H]3C[C@H]2O)C)(C)CC1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O FVIZARNDLVOMSU-IRFFNABBSA-N 0.000 claims 4
- 201000002740 oral squamous cell carcinoma Diseases 0.000 claims 4
- 230000002401 inhibitory effect Effects 0.000 claims 2
- 230000005012 migration Effects 0.000 claims 2
- 238000013508 migration Methods 0.000 claims 2
- 231100000331 toxic Toxicity 0.000 claims 2
- 230000002588 toxic effect Effects 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862658732P | 2018-04-17 | 2018-04-17 | |
| US62/658,732 | 2018-04-17 | ||
| PCT/CN2019/083058 WO2019201280A1 (en) | 2018-04-17 | 2019-04-17 | Use of ginsenoside m1 for manufacturing medicament for treating oral cancer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021517886A JP2021517886A (ja) | 2021-07-29 |
| JP2021517886A5 true JP2021517886A5 (enExample) | 2022-01-04 |
| JP7307732B2 JP7307732B2 (ja) | 2023-07-12 |
Family
ID=68239265
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020538940A Active JP7307732B2 (ja) | 2018-04-17 | 2019-04-17 | 口腔癌治療用の医薬の製造ためのジンセノサイドｍ１の使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US11524021B2 (enExample) |
| EP (1) | EP3668519B1 (enExample) |
| JP (1) | JP7307732B2 (enExample) |
| KR (1) | KR102709520B1 (enExample) |
| CN (1) | CN111615393B (enExample) |
| DK (1) | DK3668519T3 (enExample) |
| ES (1) | ES2889404T3 (enExample) |
| TW (1) | TWI820118B (enExample) |
| WO (1) | WO2019201280A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20210353225A1 (en) * | 2020-05-18 | 2021-11-18 | Chemimage Corporation | Systems and methods for detecting oral cancer using molecular chemical imaging |
| CN115300624A (zh) * | 2022-07-08 | 2022-11-08 | 中国医学科学院药用植物研究所 | 人参皂苷联合pd-1阻断剂在制备抗头颈鳞癌药物中的应用 |
| KR20250057225A (ko) | 2023-10-19 | 2025-04-29 | 단국대학교 천안캠퍼스 산학협력단 | 차가버섯 추출물을 포함하는 구강암 예방 또는 치료용 조성물 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59181217A (ja) * | 1983-03-30 | 1984-10-15 | Rooto Seiyaku Kk | ダンマラン系化合物を含有する抗癌剤組成物 |
| US20030185910A1 (en) * | 2002-02-08 | 2003-10-02 | Taik Koo Yun | Cancer preventive composition comprising ginsenoside glycosides of red ginseng |
| WO2005034963A1 (en) * | 2003-10-15 | 2005-04-21 | Panagin Pharmaceuticals Inc. | USE OF GINSENOSIDES Rh2 & Rg3, AND AGLYCON GINSENOSIDES FOR THE PREVENTION OF CANCER |
| CN103694297A (zh) * | 2013-11-19 | 2014-04-02 | 大连杰信生物科技有限公司 | 提高人参皂苷m1与癸酰氯单酯化选择性的合成方法 |
| US9844560B2 (en) * | 2014-05-02 | 2017-12-19 | Sheau-Long Lee | Use of ginsenoside M1 for treating lupus nephritis |
| US10130647B2 (en) * | 2015-03-17 | 2018-11-20 | Sheau-Long Lee | Use of ginsenoside M1 for preventing or treating silicosis |
| KR101722547B1 (ko) | 2015-05-22 | 2017-04-04 | 한국과학기술원 | 파낙사디올류 진세노사이드 화합물을 포함하는 항암보조제 |
| CN106236761A (zh) | 2016-07-27 | 2016-12-21 | 陕西巨子生物技术有限公司 | 一种包含稀有人参皂苷c‑k的稀有人参皂苷组合物 |
-
2019
- 2019-04-17 US US16/958,902 patent/US11524021B2/en active Active
- 2019-04-17 ES ES19787619T patent/ES2889404T3/es active Active
- 2019-04-17 DK DK19787619.6T patent/DK3668519T3/da active
- 2019-04-17 WO PCT/CN2019/083058 patent/WO2019201280A1/en not_active Ceased
- 2019-04-17 CN CN201980007031.0A patent/CN111615393B/zh active Active
- 2019-04-17 TW TW108113486A patent/TWI820118B/zh active
- 2019-04-17 KR KR1020207020053A patent/KR102709520B1/ko active Active
- 2019-04-17 JP JP2020538940A patent/JP7307732B2/ja active Active
- 2019-04-17 EP EP19787619.6A patent/EP3668519B1/en active Active
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