JP2021516232A5 - - Google Patents

Info

Publication number
JP2021516232A5
JP2021516232A5 JP2020545562A JP2020545562A JP2021516232A5 JP 2021516232 A5 JP2021516232 A5 JP 2021516232A5 JP 2020545562 A JP2020545562 A JP 2020545562A JP 2020545562 A JP2020545562 A JP 2020545562A JP 2021516232 A5 JP2021516232 A5 JP 2021516232A5
Authority
JP
Japan
Application number
JP2020545562A
Other languages
Japanese (ja)
Other versions
JPWO2019169123A5 (https=
JP7326306B2 (ja
JP2021516232A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/020032 external-priority patent/WO2019169123A1/en
Publication of JP2021516232A publication Critical patent/JP2021516232A/ja
Publication of JP2021516232A5 publication Critical patent/JP2021516232A5/ja
Publication of JPWO2019169123A5 publication Critical patent/JPWO2019169123A5/ja
Application granted granted Critical
Publication of JP7326306B2 publication Critical patent/JP7326306B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020545562A 2018-03-01 2019-02-28 免疫調節剤として有用な化合物 Active JP7326306B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862637009P 2018-03-01 2018-03-01
US62/637,009 2018-03-01
PCT/US2019/020032 WO2019169123A1 (en) 2018-03-01 2019-02-28 Compounds useful as immunomodulators

Publications (4)

Publication Number Publication Date
JP2021516232A JP2021516232A (ja) 2021-07-01
JP2021516232A5 true JP2021516232A5 (https=) 2023-05-29
JPWO2019169123A5 JPWO2019169123A5 (https=) 2023-05-29
JP7326306B2 JP7326306B2 (ja) 2023-08-15

Family

ID=65729475

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020545562A Active JP7326306B2 (ja) 2018-03-01 2019-02-28 免疫調節剤として有用な化合物

Country Status (7)

Country Link
US (1) US11578054B2 (https=)
EP (1) EP3759093B1 (https=)
JP (1) JP7326306B2 (https=)
KR (1) KR102758923B1 (https=)
CN (1) CN112041312A (https=)
ES (1) ES2933601T3 (https=)
WO (1) WO2019169123A1 (https=)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018005374A1 (en) 2016-06-27 2018-01-04 Chemocentryx, Inc. Immunomodulator compounds
KR20190133714A (ko) 2017-03-27 2019-12-03 브리스톨-마이어스 스큅 컴퍼니 면역조정제로서 유용한 치환된 이소퀴놀린 유도체
US11130740B2 (en) 2017-04-25 2021-09-28 Arbutus Biopharma Corporation Substituted 2,3-dihydro-1H-indene analogs and methods using same
AU2018306619B2 (en) 2017-07-28 2022-06-02 Chemocentryx, Inc. Immunomodulator compounds
CN111225665B (zh) 2017-08-08 2023-12-08 凯莫森特里克斯股份有限公司 大环免疫调节剂
JP7214752B2 (ja) 2018-01-23 2023-01-30 ブリストル-マイヤーズ スクイブ カンパニー 免疫調節剤として有用な2,8-ジアシル-2,8-ジアザスピロ[5.5]ウンデカン化合物
JP7387616B2 (ja) 2018-02-22 2023-11-28 ケモセントリックス,インコーポレイティド Pd-l1アンタゴニストとしてのインダン-アミン
US12083118B2 (en) 2018-03-29 2024-09-10 Arbutus Biopharma Corporation Substituted 1,1′-biphenyl compounds, analogues thereof, and methods using same
US20210236476A1 (en) * 2018-08-29 2021-08-05 Chemocentryx, Inc. Methods of treating cancer with small molecule pd-l1 inhibitors
CN113891748A (zh) 2019-03-28 2022-01-04 百时美施贵宝公司 治疗肿瘤的方法
KR20210146348A (ko) 2019-03-28 2021-12-03 브리스톨-마이어스 스큅 컴퍼니 종양을 치료하는 방법
AU2020276277B2 (en) 2019-05-15 2025-03-20 Chemocentryx, Inc. Triaryl compounds for treatment of PD-L1 diseases
JP2022534967A (ja) 2019-05-30 2022-08-04 ブリストル-マイヤーズ スクイブ カンパニー 多腫瘍遺伝子シグネチャーおよびその使用
KR20220016155A (ko) 2019-05-30 2022-02-08 브리스톨-마이어스 스큅 컴퍼니 면역-종양학 (i-o) 요법에 적합한 대상체를 확인하는 방법
EP3977132A1 (en) 2019-05-30 2022-04-06 Bristol-Myers Squibb Company Cell localization signature and combination therapy
SG11202112875UA (en) 2019-06-20 2021-12-30 Chemocentryx Inc Compounds for treatment of pd-l1 diseases
BR112021025888A2 (pt) 2019-07-10 2022-04-26 Chemocentryx Inc Indanos como inibidores de pd-l1
CN112457305B (zh) * 2019-09-09 2025-01-10 上海长森药业有限公司 含三环结构的芳香杂环化合物,及其制备方法和应用
CA3153777A1 (en) 2019-09-22 2021-03-25 Bristol-Myers Squibb Company Quantitative spatial profiling for lag-3 antagonist therapy
CN114555080B (zh) 2019-10-16 2025-10-10 凯莫森特里克斯股份有限公司 用于治疗pd-l1疾病的杂芳基联苯胺
AU2020368393B2 (en) 2019-10-16 2026-01-08 Chemocentryx, Inc. Heteroaryl-biphenyl amides for the treatment of PD-L1 diseases
BR112022008191A2 (pt) 2019-11-08 2022-07-12 Bristol Myers Squibb Co Terapia com antagonista de lag-3 para melanoma
BR112023003427A2 (pt) 2020-08-28 2023-03-21 Bristol Myers Squibb Co Terapia com antagonista de lag-3 para carcinoma hepatocelular
AU2021334361A1 (en) 2020-08-31 2023-05-11 Bristol-Myers Squibb Company Cell localization signature and immunotherapy
WO2022087402A1 (en) 2020-10-23 2022-04-28 Bristol-Myers Squibb Company Lag-3 antagonist therapy for lung cancer
WO2022120179A1 (en) 2020-12-03 2022-06-09 Bristol-Myers Squibb Company Multi-tumor gene signatures and uses thereof
US20240181052A1 (en) 2021-03-29 2024-06-06 Juno Therapeutics, Inc. Methods for dosing and treatment with a combination of a checkpoint inhibitor therapy and a car t cell therapy
US20240327389A1 (en) * 2021-05-05 2024-10-03 Bristol-Myers Squibb Company Lactone and lactam containing compounds useful as immunomodulators
KR20240099362A (ko) 2021-10-29 2024-06-28 브리스톨-마이어스 스큅 컴퍼니 혈액암에 대한 lag-3 길항제 요법
CA3249004A1 (en) 2022-01-26 2023-08-03 Bristol-Myers Squibb Company Polytherapy for Hepatocellular Carcinoma
US20230326022A1 (en) 2022-04-08 2023-10-12 Bristol-Myers Squibb Company Machine Learning Identification, Classification, and Quantification of Tertiary Lymphoid Structures
CN120731228A (zh) 2022-12-21 2025-09-30 百时美施贵宝公司 肺癌的组合疗法
WO2024196952A1 (en) 2023-03-20 2024-09-26 Bristol-Myers Squibb Company Tumor subtype assessment for cancer therapy
WO2025245489A1 (en) 2024-05-24 2025-11-27 Bristol-Myers Squibb Company Treatment of tumors in subjects having fgl-1 positive samples

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6410690B1 (en) 1995-06-07 2002-06-25 Medarex, Inc. Therapeutic compounds comprised of anti-Fc receptor antibodies
US5811097A (en) 1995-07-25 1998-09-22 The Regents Of The University Of California Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling
US5922845A (en) 1996-07-11 1999-07-13 Medarex, Inc. Therapeutic multispecific compounds comprised of anti-Fcα receptor antibodies
TW200815377A (en) 2006-04-24 2008-04-01 Astellas Pharma Inc Oxadiazolidinedione compound
JP6417419B2 (ja) 2013-09-04 2018-11-07 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company 免疫調節剤として有用な化合物
US9850225B2 (en) * 2014-04-14 2017-12-26 Bristol-Myers Squibb Company Compounds useful as immunomodulators
US10745382B2 (en) 2015-10-15 2020-08-18 Bristol-Myers Squibb Company Compounds useful as immunomodulators
WO2018005374A1 (en) * 2016-06-27 2018-01-04 Chemocentryx, Inc. Immunomodulator compounds
CN109689640B (zh) 2016-07-08 2022-01-04 百时美施贵宝公司 可用作免疫调节剂的化合物
US10144706B2 (en) 2016-09-01 2018-12-04 Bristol-Myers Squibb Company Compounds useful as immunomodulators
JP7106572B2 (ja) 2016-12-20 2022-07-26 ブリストル-マイヤーズ スクイブ カンパニー 免疫調節剤として有用な化合物
KR20190133714A (ko) 2017-03-27 2019-12-03 브리스톨-마이어스 스큅 컴퍼니 면역조정제로서 유용한 치환된 이소퀴놀린 유도체
AU2018306619B2 (en) * 2017-07-28 2022-06-02 Chemocentryx, Inc. Immunomodulator compounds
JP7214752B2 (ja) 2018-01-23 2023-01-30 ブリストル-マイヤーズ スクイブ カンパニー 免疫調節剤として有用な2,8-ジアシル-2,8-ジアザスピロ[5.5]ウンデカン化合物

Similar Documents

Publication Publication Date Title
JP2021516232A5 (https=)
BR112019017762A2 (https=)
BR112021017339A2 (https=)
BR112021018450A2 (https=)
BR112021017637A2 (https=)
BR112021017892A2 (https=)
BR112021017782A2 (https=)
BR112021016821A2 (https=)
BR112021017939A2 (https=)
BR112021017738A2 (https=)
BR112021016996A2 (https=)
BR112021008711A2 (https=)
BR112019016141A2 (https=)
BR112021017728A2 (https=)
BR112021013944A2 (https=)
BR112021018452A2 (https=)
BR112021017703A2 (https=)
BR112021018102A2 (https=)
BR112019016142A2 (https=)
BR112019016138A2 (https=)
BR112021017732A2 (https=)
BR112021017234A2 (https=)
BR112021017355A2 (https=)
BR112021018168A2 (https=)
BR112021018093A2 (https=)