JP2021515584A5 - - Google Patents

Info

Publication number
JP2021515584A5
JP2021515584A5 JP2020549634A JP2020549634A JP2021515584A5 JP 2021515584 A5 JP2021515584 A5 JP 2021515584A5 JP 2020549634 A JP2020549634 A JP 2020549634A JP 2020549634 A JP2020549634 A JP 2020549634A JP 2021515584 A5 JP2021515584 A5 JP 2021515584A5
Authority
JP
Japan
Prior art keywords
concentration
production bioreactor
ppm
conditions
sensitizer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020549634A
Other languages
English (en)
Japanese (ja)
Other versions
JP7816863B2 (ja
JP2021515584A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/022530 external-priority patent/WO2019178508A1/en
Publication of JP2021515584A publication Critical patent/JP2021515584A/ja
Publication of JP2021515584A5 publication Critical patent/JP2021515584A5/ja
Priority to JP2023203588A priority Critical patent/JP2024023489A/ja
Application granted granted Critical
Publication of JP7816863B2 publication Critical patent/JP7816863B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020549634A 2018-03-16 2019-03-15 産生バイオリアクターにおける細胞生存度を改善するための方法 Active JP7816863B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023203588A JP2024023489A (ja) 2018-03-16 2023-12-01 産生バイオリアクターにおける細胞生存度を改善するための方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862644339P 2018-03-16 2018-03-16
US62/644,339 2018-03-16
US201862645755P 2018-03-20 2018-03-20
US62/645,755 2018-03-20
PCT/US2019/022530 WO2019178508A1 (en) 2018-03-16 2019-03-15 Methods for improving cell viability in a production bioreactor

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023203588A Division JP2024023489A (ja) 2018-03-16 2023-12-01 産生バイオリアクターにおける細胞生存度を改善するための方法

Publications (3)

Publication Number Publication Date
JP2021515584A JP2021515584A (ja) 2021-06-24
JP2021515584A5 true JP2021515584A5 (https=) 2022-03-18
JP7816863B2 JP7816863B2 (ja) 2026-02-18

Family

ID=65952204

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020549634A Active JP7816863B2 (ja) 2018-03-16 2019-03-15 産生バイオリアクターにおける細胞生存度を改善するための方法
JP2023203588A Pending JP2024023489A (ja) 2018-03-16 2023-12-01 産生バイオリアクターにおける細胞生存度を改善するための方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023203588A Pending JP2024023489A (ja) 2018-03-16 2023-12-01 産生バイオリアクターにおける細胞生存度を改善するための方法

Country Status (18)

Country Link
US (2) US11391725B2 (https=)
EP (2) EP3765846B1 (https=)
JP (2) JP7816863B2 (https=)
KR (2) KR102757905B1 (https=)
CN (2) CN119709931A (https=)
AU (1) AU2019236246B2 (https=)
BR (1) BR112020018823A2 (https=)
CA (1) CA3094076C (https=)
ES (1) ES3009097T3 (https=)
HU (1) HUE069711T2 (https=)
IL (2) IL319295A (https=)
MA (1) MA52007A (https=)
MX (2) MX2020009605A (https=)
PL (1) PL3765846T3 (https=)
SG (1) SG11202009047TA (https=)
TW (2) TWI835779B (https=)
WO (1) WO2019178508A1 (https=)
ZA (2) ZA202005741B (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4410957A4 (en) * 2021-09-30 2026-01-28 Fujifilm Corp CELL CULTURE PROCESS AND PROCESS FOR PRODUCING USEFUL SUBSTANCE
EP4594462A1 (en) 2022-09-28 2025-08-06 Genzyme Corporation Systems and devices for producing biological products and methods of using the same
US20240263122A1 (en) * 2023-02-08 2024-08-08 National Central University Bioreactor apparatus, ion-exchange substrate and method for regulation of ion concentration and cell culture thereof

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5563068A (en) * 1994-04-21 1996-10-08 Genetic Therapy, Inc. Bioreactor
WO2006089002A2 (en) * 2005-02-15 2006-08-24 Yale University Method for high throughput screening for antibodies and proteins inducing apoptosis
AU2007294731B2 (en) * 2006-09-13 2014-04-17 Abbvie Inc. Cell culture improvements
EP2500416A1 (en) * 2006-09-13 2012-09-19 Abbott Laboratories Cell culture improvements
AU2008246928B2 (en) * 2007-05-07 2014-04-17 Protalix Ltd. Large scale disposable bioreactor
WO2010120514A2 (en) 2009-03-31 2010-10-21 The Trustees Of The University Of Pennsylvania Antigen-binding proteins comprising recombinant protein scaffolds
CN104962539B (zh) * 2009-07-31 2019-09-17 百深公司 用于adamts蛋白表达的细胞培养基
EP2943563A1 (en) * 2013-01-10 2015-11-18 Biogen MA Inc. Medium supplements for improved process performance
SG10201806083RA (en) * 2013-02-22 2018-08-30 Genzyme Corp Microcarrier perfusion culturing methods and uses thereof
WO2014151901A1 (en) * 2013-03-14 2014-09-25 Abbvie Inc. Improvement of mammalian cell culture performance through surfactant supplementation of feed media
CA2905180C (en) * 2013-03-15 2023-03-07 Alder Biopharmaceuticals, Inc. Temperature shift for high yield expression of polypeptides in yeast and other transformed cells
EP3003325A4 (en) * 2013-05-29 2017-01-11 Biogen MA Inc. Methods of evaluating cell culture additives
BR112016017660B1 (pt) * 2014-02-27 2022-04-19 F. Hoffmann-La Roche Ag Método para a produção de uma glicoproteína recombinante
SG10202001034PA (en) * 2014-12-22 2020-04-29 Genzyme Corp Methods of culturing a mammalian cell
TWI541353B (zh) * 2014-12-25 2016-07-11 財團法人工業技術研究院 產生嗜熱性鹼性蛋白酶生產菌屬（Ｔｅｐｉｄｉｍｏｎａｓ）之胞外蛋白的方法
CN108350440A (zh) * 2015-08-17 2018-07-31 阿雷克森制药公司 碱性磷酸酯的制造

Similar Documents

Publication Publication Date Title
JP2021515584A5 (https=)
Boore et al. Sequencing and comparing whole mitochondrial genomes of animals
Sieck et al. Development of a scale-down model of hydrodynamic stress to study the performance of an industrial CHO cell line under simulated production scale bioreactor conditions
Saporiti et al. Porcine circovirus 3 detection in aborted fetuses and stillborn piglets from swine reproductive failure cases
Heath et al. Cell culture process development: advances in process engineering
Liu et al. High throughput gene expression profiling of yeast colonies with microgel-culture Drop-seq
Hwang et al. Disk structure on the performance of a rotating-disk dynamic filter: A case study on microalgae microfiltration
JP7727664B2 (ja) バイオリアクターにおける治療用細胞のスケーラブルな製造のためのシステムおよび方法
Wang et al. 2-D clinostat for simulated microgravity experiments with Arabidopsis seedlings
JP2015165823A5 (https=)
Ciesla Dust coagulation and settling in layered protoplanetary disks
Feng et al. X-ray imaging of alloy solidification: crystal formation, growth, instability and defects
Hong et al. Freckle defect formation near the casting interfaces of directionally solidified superalloys
CN111757927A (zh) 用于根器官培养物的生物反应器
Lazaro-Nebreda et al. Degassing of aluminum alloy melts by high shear melt conditioning technology: An overview
JP2024023489A5 (https=)
Tanaka et al. Improvement of gene delivery and mutation efficiency in the CRISPR-Cas9 wheat (Triticum aestivum L.) genomics system via biolistics
JP2024504914A5 (https=)
Augustine et al. Targeted mutagenesis in Nicotiana tabacum ADF gene using shockwave‐mediated ribonucleoprotein delivery increases osmotic stress tolerance
Wang et al. Continuous casting of Incoloy800H superalloy billet under an alternating electromagnetic field
Lee et al. Mechanical stability of immobilized biocatalysts (CLECs) in dilute agitated suspensions
Khalili et al. Flow characteristics in an airlift membrane bioreactor
JP2020068741A5 (https=)
Hill et al. Computational fluid dynamics based digital twins of fixed bed bioreactors validate scaling principles for recombinant adeno‐associated virus gene therapy manufacturing
JPH05284966A (ja) 通気撹拌二段階培養法