JP2021514354A - ＩＬ−２２Ｆｃ融合タンパク質による治療のための投与 - Google Patents

ＩＬ−２２Ｆｃ融合タンパク質による治療のための投与 Download PDF

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JP2021514354A
JP2021514354A JP2020543145A JP2020543145A JP2021514354A JP 2021514354 A JP2021514354 A JP 2021514354A JP 2020543145 A JP2020543145 A JP 2020543145A JP 2020543145 A JP2020543145 A JP 2020543145A JP 2021514354 A JP2021514354 A JP 2021514354A
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weeks
subject
fusion protein
dosing
administered
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JPWO2019165140A5 (https=
JP2021514354A5 (https=
Inventor
マシュー カロ，
マシュー カロ，
ティモシー ゼン‐チオ ルー，
ティモシー ゼン‐チオ ルー，
シダールス スクマラン，
シダールス スクマラン，
イェン ワン，
イェン ワン，
ピーター ウィリアム デイ，
ピーター ウィリアム デイ，
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Genentech Inc
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Genentech Inc
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Publication of JP2021514354A publication Critical patent/JP2021514354A/ja
Publication of JPWO2019165140A5 publication Critical patent/JPWO2019165140A5/ja
Publication of JP2021514354A5 publication Critical patent/JP2021514354A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Transplantation (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2020543145A 2018-02-21 2019-02-21 ＩＬ−２２Ｆｃ融合タンパク質による治療のための投与 Pending JP2021514354A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862633534P 2018-02-21 2018-02-21
US62/633,534 2018-02-21
PCT/US2019/019042 WO2019165140A1 (en) 2018-02-21 2019-02-21 DOSING FOR TREATMENT WITH IL-22 Fc FUSION PROTEINS

Publications (3)

Publication Number Publication Date
JP2021514354A true JP2021514354A (ja) 2021-06-10
JPWO2019165140A5 JPWO2019165140A5 (https=) 2022-03-02
JP2021514354A5 JP2021514354A5 (https=) 2022-03-02

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JP2020543145A Pending JP2021514354A (ja) 2018-02-21 2019-02-21 ＩＬ−２２Ｆｃ融合タンパク質による治療のための投与

Country Status (14)

Country Link
US (1) US20210139552A1 (https=)
EP (1) EP3755364A1 (https=)
JP (1) JP2021514354A (https=)
KR (1) KR20200123118A (https=)
CN (1) CN111757751A (https=)
AU (1) AU2019226085A1 (https=)
CA (1) CA3091139A1 (https=)
IL (1) IL276616A (https=)
MA (1) MA51907A (https=)
MX (1) MX2020008502A (https=)
RU (1) RU2020128111A (https=)
SG (1) SG11202007694UA (https=)
TW (1) TW201946647A (https=)
WO (1) WO2019165140A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104623637A (zh) 2013-11-07 2015-05-20 健能隆医药技术（上海）有限公司 Il-22二聚体在制备静脉注射药物中的应用
WO2017181143A1 (en) 2016-04-15 2017-10-19 Generon (Shanghai) Corporation, Ltd. Use of il-22 in treating necrotizing enterocolitis
TW202118793A (zh) * 2019-07-26 2021-05-16 美商建南德克公司 以 IL-22 Fc 融合蛋白預防或治療移植物抗宿主疾病 (GVHD) 之投藥
EP4103219A4 (en) * 2020-02-14 2024-03-27 Evive Biotechnology (Shanghai) Ltd METHODS OF PREVENTING OR TREATING VIRUS-INDUCED ORGAN INJURY OR INSUFFICIENCY WITH IL-22 DIMER
EP4106794A4 (en) 2020-02-19 2024-03-20 Evive Biotechnology (Shanghai) Ltd METHOD FOR TREATING TRANSPLANT AND HOST DISEASE
WO2021207662A1 (en) * 2020-04-10 2021-10-14 Genentech, Inc. Use of il-22fc for the treatment or prevention of pneumonia, acute respiratory distress syndrome, or cytokine release syndrome

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Publication number Priority date Publication date Assignee Title
JP2016522795A (ja) * 2013-03-15 2016-08-04 ジェネンテック， インコーポレイテッド ＩＬ−２２ポリペプチド及びＩＬ−２２Ｆｃ融合タンパク質並びに使用方法

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Publication number Publication date
CN111757751A (zh) 2020-10-09
TW201946647A (zh) 2019-12-16
SG11202007694UA (en) 2020-09-29
US20210139552A1 (en) 2021-05-13
AU2019226085A1 (en) 2020-09-17
MA51907A (fr) 2021-05-26
IL276616A (en) 2020-09-30
CA3091139A1 (en) 2019-08-29
KR20200123118A (ko) 2020-10-28
EP3755364A1 (en) 2020-12-30
WO2019165140A1 (en) 2019-08-29
RU2020128111A (ru) 2022-03-21
MX2020008502A (es) 2020-09-25

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