JP2021514007A5 - - Google Patents

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Publication number
JP2021514007A5
JP2021514007A5 JP2020544852A JP2020544852A JP2021514007A5 JP 2021514007 A5 JP2021514007 A5 JP 2021514007A5 JP 2020544852 A JP2020544852 A JP 2020544852A JP 2020544852 A JP2020544852 A JP 2020544852A JP 2021514007 A5 JP2021514007 A5 JP 2021514007A5
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JP
Japan
Prior art keywords
pharmaceutically acceptable
compound
acceptable salt
leukemia
lymphoma
Prior art date
Application number
JP2020544852A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021514007A (ja
JP7317032B2 (ja
JPWO2019169001A5 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/019856 external-priority patent/WO2019169001A1/en
Publication of JP2021514007A publication Critical patent/JP2021514007A/ja
Publication of JPWO2019169001A5 publication Critical patent/JPWO2019169001A5/ja
Publication of JP2021514007A5 publication Critical patent/JP2021514007A5/ja
Priority to JP2023096315A priority Critical patent/JP7521070B2/ja
Application granted granted Critical
Publication of JP7317032B2 publication Critical patent/JP7317032B2/ja
Priority to JP2024111017A priority patent/JP2024138421A/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2020544852A 2018-02-27 2019-02-27 Ｔｃｒ－ｎｃｋ相互作用の阻害剤としてのクロメン誘導体 Active JP7317032B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023096315A JP7521070B2 (ja) 2018-02-27 2023-06-12 Ｔｃｒ－ｎｃｋ相互作用の阻害剤としてのクロメン誘導体
JP2024111017A JP2024138421A (ja) 2018-02-27 2024-07-10 Ｔｃｒ－ｎｃｋ相互作用の阻害剤としてのクロメン誘導体

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862635834P 2018-02-27 2018-02-27
US62/635,834 2018-02-27
PCT/US2019/019856 WO2019169001A1 (en) 2018-02-27 2019-02-27 Chromene derivatives as inhibitors of tcr-nck interaction

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023096315A Division JP7521070B2 (ja) 2018-02-27 2023-06-12 Ｔｃｒ－ｎｃｋ相互作用の阻害剤としてのクロメン誘導体

Publications (4)

Publication Number Publication Date
JP2021514007A JP2021514007A (ja) 2021-06-03
JPWO2019169001A5 JPWO2019169001A5 (https=) 2022-03-02
JP2021514007A5 true JP2021514007A5 (https=) 2022-03-02
JP7317032B2 JP7317032B2 (ja) 2023-07-28

Family

ID=65724589

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2020544852A Active JP7317032B2 (ja) 2018-02-27 2019-02-27 Ｔｃｒ－ｎｃｋ相互作用の阻害剤としてのクロメン誘導体
JP2023096315A Active JP7521070B2 (ja) 2018-02-27 2023-06-12 Ｔｃｒ－ｎｃｋ相互作用の阻害剤としてのクロメン誘導体
JP2024111017A Pending JP2024138421A (ja) 2018-02-27 2024-07-10 Ｔｃｒ－ｎｃｋ相互作用の阻害剤としてのクロメン誘導体

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2023096315A Active JP7521070B2 (ja) 2018-02-27 2023-06-12 Ｔｃｒ－ｎｃｋ相互作用の阻害剤としてのクロメン誘導体
JP2024111017A Pending JP2024138421A (ja) 2018-02-27 2024-07-10 Ｔｃｒ－ｎｃｋ相互作用の阻害剤としてのクロメン誘導体

Country Status (16)

Country Link
US (5) US10696663B2 (https=)
EP (1) EP3759086A1 (https=)
JP (3) JP7317032B2 (https=)
KR (2) KR20260028873A (https=)
CN (2) CN117304157A (https=)
AU (2) AU2019229258B2 (https=)
BR (1) BR112020017386A2 (https=)
CA (1) CA3091202A1 (https=)
CO (1) CO2020010537A2 (https=)
EA (1) EA202091742A1 (https=)
IL (2) IL301120B2 (https=)
MX (2) MX2020008814A (https=)
PH (1) PH12020500638A1 (https=)
SG (1) SG11202008067QA (https=)
WO (1) WO2019169001A1 (https=)
ZA (1) ZA202310843B (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20260028873A (ko) 2018-02-27 2026-03-04 아텍스 바이오파마 인코포레이티드 Tcr-nck 상호 작용의 억제제로서의 크로멘 유도체
WO2025137442A1 (en) * 2023-12-22 2025-06-26 Artax Biopharma Inc. SOLID AND SALT FORMS OF TCR-NcK MODULATORS AND USES THEREOF
WO2025255109A1 (en) * 2024-06-03 2025-12-11 Artax Biopharma Inc. Combination of a chromene derivative tcr inhibitor and a pde4 inhibitor
WO2025255091A1 (en) * 2024-06-03 2025-12-11 Artax Biopharma Inc. Combination of a chromene derivative tcr inhibitor and a jak inhibitor
WO2025255093A1 (en) * 2024-06-03 2025-12-11 Artax Biopharma Inc. Combination of a car-t therapy and a chromene derivative tcr inhibitor

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