JP2021513986A5 - - Google Patents

Info

Publication number
JP2021513986A5
JP2021513986A5 JP2020543634A JP2020543634A JP2021513986A5 JP 2021513986 A5 JP2021513986 A5 JP 2021513986A5 JP 2020543634 A JP2020543634 A JP 2020543634A JP 2020543634 A JP2020543634 A JP 2020543634A JP 2021513986 A5 JP2021513986 A5 JP 2021513986A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
item
composition according
cancer
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020543634A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021513986A (ja
JP7445597B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/018225 external-priority patent/WO2019168688A2/en
Publication of JP2021513986A publication Critical patent/JP2021513986A/ja
Publication of JP2021513986A5 publication Critical patent/JP2021513986A5/ja
Application granted granted Critical
Publication of JP7445597B2 publication Critical patent/JP7445597B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020543634A 2018-02-15 2019-02-15 キノロン類似体及びそれらの塩、組成物、ならびにそれらの使用方法 Active JP7445597B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862631174P 2018-02-15 2018-02-15
US201862631171P 2018-02-15 2018-02-15
US62/631,171 2018-02-15
US62/631,174 2018-02-15
PCT/US2019/018225 WO2019168688A2 (en) 2018-02-15 2019-02-15 Quinolone analogs and their salts, compositions, and method for their use

Publications (3)

Publication Number Publication Date
JP2021513986A JP2021513986A (ja) 2021-06-03
JP2021513986A5 true JP2021513986A5 (https=) 2023-06-19
JP7445597B2 JP7445597B2 (ja) 2024-03-07

Family

ID=67805108

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020543634A Active JP7445597B2 (ja) 2018-02-15 2019-02-15 キノロン類似体及びそれらの塩、組成物、ならびにそれらの使用方法

Country Status (11)

Country Link
US (2) US20190374550A1 (https=)
EP (1) EP3752149A4 (https=)
JP (1) JP7445597B2 (https=)
KR (1) KR102914215B1 (https=)
CN (1) CN112334133A (https=)
AU (1) AU2019227294B2 (https=)
CA (1) CA3088998A1 (https=)
IL (1) IL276513A (https=)
RU (1) RU2020130050A (https=)
TW (1) TWI884912B (https=)
WO (1) WO2019168688A2 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7017509B2 (ja) 2015-11-20 2022-02-08 センワ バイオサイエンシズ インコーポレイテッド がんを治療するための四環式キノロン類似体の併用療法
CN112334133A (zh) 2018-02-15 2021-02-05 生华生物科技股份有限公司 喹诺酮类似物及其盐、组合物及其使用方法
CA3151116A1 (en) * 2019-08-14 2021-02-18 Hshiou-Ting Liu Crystalline forms of quinoline analogs and salts thereof, compositions, and their methods for use
EP4013421A4 (en) * 2019-08-14 2023-08-23 Senhwa Biosciences, Inc. TETRACYCLIC COMPOUNDS AND THEIR SALTS, COMPOSITIONS AND METHODS OF USE
US20220062294A1 (en) * 2020-09-02 2022-03-03 Senhwa Biosciences, Inc. Pharmaceutical compositions of tetracyclic quinolone analogs and their salts
WO2023059148A1 (ko) * 2021-10-08 2023-04-13 기초과학연구원 항암 치료 개선을 위한 2-클로로-n,n-디에틸에틸아민 염산염의 용도
CN118005653B (zh) * 2023-04-23 2024-12-10 信义核新(北京)生物科技有限公司 喹诺酮类似物及其用途

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4559157A (en) 1983-04-21 1985-12-17 Creative Products Resource Associates, Ltd. Cosmetic applicator useful for skin moisturizing
LU84979A1 (fr) 1983-08-30 1985-04-24 Oreal Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre dont la phase grasse contient un polyether oligomere et polyethers oligomeres nouveaux
US4820508A (en) 1987-06-23 1989-04-11 Neutrogena Corporation Skin protective composition
US4992478A (en) 1988-04-04 1991-02-12 Warner-Lambert Company Antiinflammatory skin moisturizing composition and method of preparing same
US4938949A (en) 1988-09-12 1990-07-03 University Of New York Treatment of damaged bone marrow and dosage units therefor
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
EP1165508B1 (en) 1999-04-07 2004-06-23 The University of Virginia Patent Foundation Anticancer calcium channel blockers
JP2005511743A (ja) 2001-12-13 2005-04-28 ウォックハート・リミテッド 新世代の三重標的化したキラルな広域スペクトラム抗菌性の7位置換ピペリジノ−キノロンカルボン酸誘導体、その調製方法、組成物、および医薬としての使用
US6900224B2 (en) 2002-07-31 2005-05-31 The Procter & Gamble Company Antimicrobial quinolones, their compositions and uses
PL1633724T3 (pl) 2003-03-12 2011-10-31 Kudos Pharm Ltd Pochodne ftalazynonu
US7531530B2 (en) 2003-07-25 2009-05-12 Cancer Research Technology Limited Therapeutic compounds
US20050118291A1 (en) 2003-09-10 2005-06-02 Mian-Ying Wang Formulations and methods for treating breast cancer with Morinda citrifolia and methylsulfonymethane
WO2005033108A1 (en) 2003-09-22 2005-04-14 Janssen Pharmaceutica, N.V. 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
PL2305221T3 (pl) 2003-12-01 2015-11-30 Kudos Pharm Ltd Inhibitory naprawy uszkodzeń DNA w leczeniu raka
WO2005113556A1 (en) 2004-05-13 2005-12-01 Icos Corporation Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta
WO2006034113A2 (en) 2004-09-17 2006-03-30 Cylene Pharmaceuticals, Inc. Quinolone analogs as cell proliferation inhibitors
US7816524B2 (en) 2005-08-05 2010-10-19 Cylene Pharmaceuticals, Inc. Methods of preparing quinolone analogs
JP2009504192A (ja) 2005-08-19 2009-02-05 サイリーン ファーマシューティカルズ インコーポレーティッド ヒトリボソームDNA(rDNA)およびリボソームRNA(rRNA)核酸ならびにそれらの使用
AR057555A1 (es) 2005-10-27 2007-12-05 Merck Frosst Canada Ltd Un inhibidor de fosfodiesterasa-4 4-oxo-1-(3-sustituido fenil-1,4-dihidro-1,8-naftiridin-3-carboxamida y un procedimiento de preparacion del mismo
US20090291437A1 (en) * 2005-11-02 2009-11-26 O'brien Sean Methods for targeting quadruplex sequences
EP2023720A4 (en) 2006-05-17 2009-06-10 Cylene Pharmaceuticals Inc TETRACYCLIC IMIDAZOLE ANALOG
WO2007146813A2 (en) 2006-06-08 2007-12-21 Cylene Pharmaceuticals, Inc. Pyridinone analogs as cell proliferation inhibitors
WO2007146831A2 (en) 2006-06-08 2007-12-21 Cylene Pharmaceuticals, Inc. Quinolone analogs derivatized with sulfonic acid, sulfonate or sulfonamide
GB0701992D0 (en) 2007-02-02 2007-03-14 7Tm Pharma As Grehlin Receptor Modulators
US20110065687A1 (en) 2007-04-17 2011-03-17 Michael Schwaebe Hydrazide compounds and uses thereof
US7928100B2 (en) 2007-10-05 2011-04-19 Cylene Pharmaceuticals, Inc. Quinolone analogs and methods related thereto
AU2008201871A1 (en) 2008-04-16 2009-11-26 Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts Inhibition of angiogenesis and tumor metastasis
US9359605B2 (en) 2011-03-11 2016-06-07 Sarissa Inc. Method of treating cancer by inhibition of DNA repair proteins
US20140086839A1 (en) * 2011-03-17 2014-03-27 Tel Hashomer Medical Research Infrastructure And Services Ltd. Quinolone analogs for treating autoimmune diseases
WO2013133876A1 (en) 2011-12-07 2013-09-12 The Regents Of The University Of California Biomarkers for prediction of response to parp inhibition in breast cancer
US9044421B2 (en) 2012-03-28 2015-06-02 Genus Oncology, Llc Treating MUC1-expressing cancers with combination therapies
HK1203971A1 (en) 2012-05-15 2015-11-06 Bristol-Myers Squibb Company Cancer immunotherapy by disrupting pd-1/pd-l1 signaling
US20160145355A1 (en) 2013-06-24 2016-05-26 Biomed Valley Discoveries, Inc. Bispecific antibodies
ES2754207T3 (es) * 2013-11-28 2020-04-16 Tel Hashomer Medical Res Infrastructure & Services Ltd Inhibidores de la ARN polimerasa I y usos de los mismos
KR102410090B1 (ko) 2014-02-21 2022-06-16 넥타르 테라퓨틱스 (인디아) 프라이빗 리미티드 항-ctla-4 항체 또는 항-pd-1 항체와 조합한 il-2r베타-선택적 효현제
JP7017509B2 (ja) 2015-11-20 2022-02-08 センワ バイオサイエンシズ インコーポレイテッド がんを治療するための四環式キノロン類似体の併用療法
JP2018537486A (ja) * 2015-12-14 2018-12-20 センワ バイオサイエンシズ インコーポレイテッド キノロン類似体及びその塩の結晶形
US9957282B2 (en) * 2015-12-14 2018-05-01 Senhwa Biosciences, Inc. Crystalline forms of quinolone analogs and their salts
WO2017100925A1 (en) 2015-12-15 2017-06-22 British Columbia Cancer Agency Branch Metal complexed therapeutic agents and lipid-based nanoparticulate formulations thereof
WO2017205832A1 (en) * 2016-05-26 2017-11-30 Fred Hutchinson Cancer Research Center L-myc pathway targeting as a treatment for small cell lung cancer
CN112334133A (zh) 2018-02-15 2021-02-05 生华生物科技股份有限公司 喹诺酮类似物及其盐、组合物及其使用方法
EP4013421A4 (en) 2019-08-14 2023-08-23 Senhwa Biosciences, Inc. TETRACYCLIC COMPOUNDS AND THEIR SALTS, COMPOSITIONS AND METHODS OF USE
CA3151116A1 (en) 2019-08-14 2021-02-18 Hshiou-Ting Liu Crystalline forms of quinoline analogs and salts thereof, compositions, and their methods for use
US20220062294A1 (en) 2020-09-02 2022-03-03 Senhwa Biosciences, Inc. Pharmaceutical compositions of tetracyclic quinolone analogs and their salts

Similar Documents

Publication Publication Date Title
JP2021513986A5 (https=)
WO2023190748A1 (ja) 腫瘍治療用医薬組成物
CN102171214B (zh) 聚(adp-核糖)聚合酶(parp)的二氢吡啶并酞嗪酮抑制剂
CN113966335A (zh) 用于治疗癌症的egfr抑制剂
TW200932239A (en) PARP inhibitor compounds, compositions and methods of use
JP2023504230A (ja) Prmt5阻害剤の組合せ医薬
TWI633887B (zh) 用於預防及/或治療多囊性腎臟病之藥物
TW202023563A (zh) 新穎喹唑啉egfr抑制劑
CN110891576A (zh) 使用包含parp抑制剂、替莫唑胺和/或放射疗法的组合治疗癌症
RU2020130050A (ru) Аналоги хинолонов и их соли, композиции и способ их применения
WO2023147311A1 (en) Ubiquitin-specific-processing protease 1 (usp1) inhibitors for the treatment of solid tumors
US20260027087A1 (en) Dosing regimens comprising a kat6 inhibitor for the treatment of cancer
CN105283180A (zh) Pi3k抑制剂与微管去稳定剂的药物组合
CN101357134A (zh) 抗肿瘤效果增强剂和抗肿瘤剂
TW200838537A (en) Substituted quinazolines
EP4656193A1 (en) Pharmaceutical composition for treating tumors
AU2004273605B2 (en) Treatment of gastrointestinal stromal tumors with imatinib and midostaurin
CN116672345A (zh) Parp抑制剂和细胞毒性剂的联合产品及其用途
TW200827361A (en) Antitumor pharmaceutical composition
CN111718328A (zh) 4-甲基-1h-二芳基吡唑类衍生物在制备抗肿瘤药物中的用途
US20220002287A1 (en) Indazole kinase inhibitor and use thereof
JP5794873B2 (ja) 抗腫瘍剤
US20250235458A1 (en) Benzimidazole derivatives for use in the treatment or prevention of a histiocytosis or a craniopharyngioma
US20130203789A1 (en) Novel Inhibitors of LYN Kinase and Methods Using Same
HK40108895A (zh) Kras g12d抑制剂与pi3ka抑制剂的组合及相关治疗方法