JP2021513968A5 - - Google Patents
Info
- Publication number
- JP2021513968A5 JP2021513968A5 JP2020543358A JP2020543358A JP2021513968A5 JP 2021513968 A5 JP2021513968 A5 JP 2021513968A5 JP 2020543358 A JP2020543358 A JP 2020543358A JP 2020543358 A JP2020543358 A JP 2020543358A JP 2021513968 A5 JP2021513968 A5 JP 2021513968A5
- Authority
- JP
- Japan
- Prior art keywords
- conjugate
- independently
- target
- biological sample
- aliphatic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862631390P | 2018-02-15 | 2018-02-15 | |
| US62/631,390 | 2018-02-15 | ||
| PCT/US2019/018153 WO2019161159A1 (en) | 2018-02-15 | 2019-02-15 | Non-aggregating heptamethine cyanine fluorophores for in vivo imaging |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021513968A JP2021513968A (ja) | 2021-06-03 |
| JP2021513968A5 true JP2021513968A5 (https=) | 2022-01-17 |
| JP7085633B2 JP7085633B2 (ja) | 2022-06-16 |
Family
ID=65812377
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020543808A Pending JP2021513988A (ja) | 2018-02-15 | 2019-02-14 | 胆道系及び腎臓系の蛍光マーカーとして使用するためのヘプタメチン系シアニン |
| JP2020543358A Active JP7085633B2 (ja) | 2018-02-15 | 2019-02-15 | ｉｎ ｖｉｖｏ画像化のための非凝集性ヘプタメチンシアニンフルオロフォア |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020543808A Pending JP2021513988A (ja) | 2018-02-15 | 2019-02-14 | 胆道系及び腎臓系の蛍光マーカーとして使用するためのヘプタメチン系シアニン |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US11787764B2 (https=) |
| EP (2) | EP3752486A4 (https=) |
| JP (2) | JP2021513988A (https=) |
| KR (1) | KR20200122338A (https=) |
| AU (1) | AU2019222477B2 (https=) |
| CA (2) | CA3091423A1 (https=) |
| WO (2) | WO2019161091A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11787764B2 (en) | 2018-02-15 | 2023-10-17 | Children's National Medical Center | Heptamethine cyanines for use as fluorescent markers of the biliary and renal systems |
| AU2019325658B2 (en) | 2018-08-23 | 2024-02-15 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Water soluble novel cyanine fluorophore with tunable properties between near IR and SWIR region for in vivo imaging |
| CA3167456A1 (en) | 2020-02-10 | 2021-08-19 | C-Biomex Co., Ltd. | Amphoteric fluorescent substance capable of being attached to biomaterials |
| JP7441306B2 (ja) | 2020-04-24 | 2024-02-29 | 富士フイルム株式会社 | 化合物及びこれを用いた標識生体物質 |
| WO2022203930A1 (en) * | 2021-03-24 | 2022-09-29 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Fluorogenic cyanine carbamates |
| EP4357437A4 (en) * | 2021-06-18 | 2025-02-19 | FUJIFILM Corporation | COMPOUND AND MARKED BIOMATERIAL USING SAME |
| US20250009908A1 (en) * | 2021-10-05 | 2025-01-09 | Vrije Universiteit Brussel | Fluorescently Labeled Immunoglobulin Single Variable Domains |
| CN115403503B (zh) * | 2022-09-02 | 2023-05-26 | 中国药科大学 | 七甲川花菁素类染料偶联物、制法、药物组合物和应用 |
| EP4428201A1 (en) * | 2023-03-07 | 2024-09-11 | European Central Bank | New infrared absorbers |
| CN119390778A (zh) * | 2024-10-29 | 2025-02-07 | 北京声光纳医疗科技有限公司 | 一种两性离子化、基于点击化学反应的荧光探针及其制备方法与应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20060017585A (ko) * | 2003-04-04 | 2006-02-24 | 유니베르시떼 드 로잔느 | 암 치료용 펩타바디 |
| US8406859B2 (en) | 2008-08-10 | 2013-03-26 | Board Of Regents, The University Of Texas System | Digital light processing hyperspectral imaging apparatus |
| WO2010037069A2 (en) * | 2008-09-29 | 2010-04-01 | Mallinckrodt Inc. | Dithienopyrrole dyes for imaging and therapy |
| JP5515529B2 (ja) * | 2009-09-04 | 2014-06-11 | 国立大学法人三重大学 | 近赤外光発光化合物、その合成法及びその発光法 |
| WO2014149069A1 (en) * | 2013-03-15 | 2014-09-25 | Purdue Research Foundation | Synthesis and composition of amino acid linking groups conjugated to compounds used for the targeted imaging of tumors |
| US20150030542A1 (en) * | 2013-07-26 | 2015-01-29 | Sunil Singhal | Methods for medical imaging |
| US10280307B2 (en) * | 2014-11-05 | 2019-05-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Class of stable heptamethine cyanine fluorophores and biomedical applications thereof |
| AR102743A1 (es) * | 2014-11-26 | 2017-03-22 | Li Cor Inc | Medios de contraste ir para imágenes por fluorescencia |
| WO2017027721A1 (en) | 2015-08-12 | 2017-02-16 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Near-ir light-cleavable conjugates and conjugate precursors |
| WO2018031448A1 (en) | 2016-08-11 | 2018-02-15 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Near-ir light-cleavable conjugates and conjugate precursors |
| JP7418323B2 (ja) | 2017-08-24 | 2024-01-19 | ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ | 遠赤および近ｉｒ範囲におけるシアニンフルオロフォアの配座の束縛 |
| US11787764B2 (en) | 2018-02-15 | 2023-10-17 | Children's National Medical Center | Heptamethine cyanines for use as fluorescent markers of the biliary and renal systems |
| AU2019325658B2 (en) | 2018-08-23 | 2024-02-15 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Water soluble novel cyanine fluorophore with tunable properties between near IR and SWIR region for in vivo imaging |
-
2019
- 2019-02-14 US US16/970,155 patent/US11787764B2/en active Active
- 2019-02-14 EP EP19754834.0A patent/EP3752486A4/en not_active Withdrawn
- 2019-02-14 KR KR1020207026443A patent/KR20200122338A/ko not_active Withdrawn
- 2019-02-14 CA CA3091423A patent/CA3091423A1/en active Pending
- 2019-02-14 JP JP2020543808A patent/JP2021513988A/ja active Pending
- 2019-02-14 WO PCT/US2019/018057 patent/WO2019161091A1/en not_active Ceased
- 2019-02-15 JP JP2020543358A patent/JP7085633B2/ja active Active
- 2019-02-15 US US16/969,902 patent/US10961193B2/en active Active
- 2019-02-15 EP EP19711727.8A patent/EP3752204B1/en active Active
- 2019-02-15 AU AU2019222477A patent/AU2019222477B2/en active Active
- 2019-02-15 WO PCT/US2019/018153 patent/WO2019161159A1/en not_active Ceased
- 2019-02-15 CA CA3090797A patent/CA3090797C/en active Active
-
2021
- 2021-02-18 US US17/179,217 patent/US11746086B2/en active Active
-
2023
- 2023-07-25 US US18/358,068 patent/US20230382857A1/en active Pending
- 2023-11-27 US US18/520,027 patent/US20240140909A1/en active Pending
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