JP2021511042A5 - - Google Patents

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Publication number
JP2021511042A5
JP2021511042A5 JP2020539274A JP2020539274A JP2021511042A5 JP 2021511042 A5 JP2021511042 A5 JP 2021511042A5 JP 2020539274 A JP2020539274 A JP 2020539274A JP 2020539274 A JP2020539274 A JP 2020539274A JP 2021511042 A5 JP2021511042 A5 JP 2021511042A5
Authority
JP
Japan
Prior art keywords
oligonucleotide according
nucleotides
length
oligonucleotide
antisense
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020539274A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021511042A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/013672 external-priority patent/WO2019143621A1/en
Publication of JP2021511042A publication Critical patent/JP2021511042A/ja
Publication of JP2021511042A5 publication Critical patent/JP2021511042A5/ja
Pending legal-status Critical Current

Links

JP2020539274A 2018-01-16 2019-01-15 Aldh2発現を阻害するための組成物及び方法 Pending JP2021511042A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862617692P 2018-01-16 2018-01-16
US62/617,692 2018-01-16
PCT/US2019/013672 WO2019143621A1 (en) 2018-01-16 2019-01-15 Compositions and methods for inhibiting aldh2 expression

Publications (2)

Publication Number Publication Date
JP2021511042A JP2021511042A (ja) 2021-05-06
JP2021511042A5 true JP2021511042A5 (enExample) 2022-01-20

Family

ID=67302455

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020539274A Pending JP2021511042A (ja) 2018-01-16 2019-01-15 Aldh2発現を阻害するための組成物及び方法

Country Status (10)

Country Link
US (1) US11661603B2 (enExample)
EP (1) EP3710588A4 (enExample)
JP (1) JP2021511042A (enExample)
KR (1) KR20200109311A (enExample)
CN (1) CN111601891A (enExample)
AU (1) AU2019209324A1 (enExample)
CA (1) CA3086409A1 (enExample)
IL (1) IL275539A (enExample)
MX (1) MX2020007582A (enExample)
WO (1) WO2019143621A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200109311A (ko) 2018-01-16 2020-09-22 다이서나 파마수이티컬, 인크. Aldh2 발현을 억제하기 위한 조성물 및 방법
BR112021019793A2 (pt) * 2019-04-04 2021-12-07 Dicerna Pharmaceuticals Inc Composições e métodos para inibir expressão de gene no sistema nervoso central
AU2020268798A1 (en) * 2019-05-03 2021-11-04 Dicerna Pharmaceuticals, Inc. Double-stranded nucleic acid inhibitor molecules with shortened sense strands
EP4244356A1 (en) 2020-11-13 2023-09-20 Dicerna Pharmaceuticals, Inc. Chemical modifications for inhibiting expression of aldh2
CN113174438B (zh) * 2021-06-01 2022-07-26 中国科学院城市环境研究所 Aldh2基因多态性检测试剂盒及检测方法
CN114891808B (zh) * 2022-06-21 2023-10-27 珠海丽凡达生物技术有限公司 编码ALDH2多肽的mRNA分子、应用及mRNA药物
WO2024000237A1 (zh) * 2022-06-29 2024-01-04 河南省农业科学院植物营养与资源环境研究所 Iaa-po1基因在诱导平菇原基形成和平菇生长发育抗逆中的应用
GB202218090D0 (en) 2022-12-01 2023-01-18 Proqr Therapeutics Ii Bv Antisense oligonucleotides for the treatment of aldehyde dehydrogenase 2 deficiency
AU2023408479A1 (en) * 2022-12-19 2025-05-01 Arnatar Therapeutics, Inc Advanced rna targeting (arnatar)
CN119082043A (zh) * 2024-10-10 2024-12-06 张家界学院 Aldh2稳定表达的细胞系、构建方法及应用

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EP3735461A1 (en) 2017-11-13 2020-11-11 Silence Therapeutics GmbH Nucleic acids for inhibiting expression of aldh2 in a cell
KR20200109311A (ko) 2018-01-16 2020-09-22 다이서나 파마수이티컬, 인크. Aldh2 발현을 억제하기 위한 조성물 및 방법
BR112021019793A2 (pt) 2019-04-04 2021-12-07 Dicerna Pharmaceuticals Inc Composições e métodos para inibir expressão de gene no sistema nervoso central
EP4244356A1 (en) 2020-11-13 2023-09-20 Dicerna Pharmaceuticals, Inc. Chemical modifications for inhibiting expression of aldh2

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