JP2021508495A5 - - Google Patents

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Publication number
JP2021508495A5
JP2021508495A5 JP2020555284A JP2020555284A JP2021508495A5 JP 2021508495 A5 JP2021508495 A5 JP 2021508495A5 JP 2020555284 A JP2020555284 A JP 2020555284A JP 2020555284 A JP2020555284 A JP 2020555284A JP 2021508495 A5 JP2021508495 A5 JP 2021508495A5
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JP
Japan
Prior art keywords
seq
amino acid
antigen
monoclonal antibody
binding fragment
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Granted
Application number
JP2020555284A
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English (en)
Japanese (ja)
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JP7368670B2 (ja
JP2021508495A (ja
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Priority claimed from CN201711482969.7A external-priority patent/CN108218984B/zh
Priority claimed from CN201711486732.6A external-priority patent/CN108314731B/zh
Priority claimed from CN201711486693.XA external-priority patent/CN108314730B/zh
Priority claimed from CN201810420730.5A external-priority patent/CN108623681B/zh
Application filed filed Critical
Priority claimed from PCT/CN2018/124958 external-priority patent/WO2019129214A1/zh
Publication of JP2021508495A publication Critical patent/JP2021508495A/ja
Publication of JP2021508495A5 publication Critical patent/JP2021508495A5/ja
Application granted granted Critical
Publication of JP7368670B2 publication Critical patent/JP7368670B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2020555284A 2017-12-29 2018-12-28 破傷風毒素に対する完全天然型ヒト中和モノクロナル抗体及びその応用 Active JP7368670B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
CN201711482969.7A CN108218984B (zh) 2017-12-29 2017-12-29 一种抗破伤风毒素的全人源中和抗体
CN201711486732.6A CN108314731B (zh) 2017-12-29 2017-12-29 一种针对破伤风毒素的全人源单克隆中和抗体及其应用
CN201711486693.X 2017-12-29
CN201711482969.7 2017-12-29
CN201711486732.6 2017-12-29
CN201711486693.XA CN108314730B (zh) 2017-12-29 2017-12-29 抗破伤风毒素中和抗体及其制备与应用
CN201810420730.5 2018-05-04
CN201810420730.5A CN108623681B (zh) 2018-05-04 2018-05-04 一种抗破伤风毒素的中和抗体及应用
PCT/CN2018/124958 WO2019129214A1 (zh) 2017-12-29 2018-12-28 针对破伤风毒素的全人源单克隆中和抗体及其应用

Publications (3)

Publication Number Publication Date
JP2021508495A JP2021508495A (ja) 2021-03-11
JP2021508495A5 true JP2021508495A5 (https=) 2023-05-30
JP7368670B2 JP7368670B2 (ja) 2023-10-25

Family

ID=67063214

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020555284A Active JP7368670B2 (ja) 2017-12-29 2018-12-28 破傷風毒素に対する完全天然型ヒト中和モノクロナル抗体及びその応用

Country Status (6)

Country Link
US (1) US11725046B2 (https=)
EP (1) EP3733699A4 (https=)
JP (1) JP7368670B2 (https=)
AU (1) AU2018395100B2 (https=)
BR (1) BR112020013094A2 (https=)
WO (1) WO2019129214A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118139879A (zh) * 2021-09-07 2024-06-04 生物医学研究院 结合破伤风毒素的抗体及其用途
CN114044819B (zh) * 2021-09-29 2024-07-12 上海儒克生物科技有限公司 全羊源单克隆抗体的高通量制备方法
CN119700969A (zh) * 2023-09-27 2025-03-28 珠海泰诺麦博制药股份有限公司 一种抗破伤风毒素抗体在预防或治疗破伤风中的应用
CN118812707B (zh) * 2024-09-20 2024-12-31 北京科兴中维生物技术有限公司 抗破伤风毒素抗体及应用
CN120829503B (zh) * 2025-09-18 2025-12-26 北京科兴中维生物技术有限公司 抗破伤风毒素抗体及其制备方法与应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2627076B2 (ja) * 1988-08-19 1997-07-02 森永製菓株式会社 抗破傷風毒素ヒト型モノクローナル抗体、それを利用した破傷風毒素中和剤及びヒト型モノクローナル抗体産生ハイブリドーマ
US6657103B1 (en) * 1990-01-12 2003-12-02 Abgenix, Inc. Human antibodies derived from immunized xenomice
DK0562132T3 (da) * 1992-03-23 1999-03-22 Schweiz Serum & Impfinst Monoklonale antistoffer mod tetanustoksin og farmaceutiske præparater indeholdende dem
JP2001299360A (ja) 2000-04-28 2001-10-30 Morihiro Matsuda ヒト型抗破傷風毒素一本鎖組換え抗体フラグメント
US20040253242A1 (en) * 2000-12-05 2004-12-16 Bowdish Katherine S. Rationally designed antibodies
CN1305904C (zh) 2003-12-30 2007-03-21 龚小迪 人源的抗破伤风毒素单克隆抗体的制备和应用
CN101220096B (zh) * 2003-12-30 2010-09-29 龚小迪 人源抗破伤风毒素单克隆抗体的制备和应用
CN105153305B (zh) * 2015-06-26 2019-03-01 安泰吉（北京）生物技术有限公司 一种全人源抗破伤风毒素单克隆抗体及其衍生物制备方法和应用
CN108314731B (zh) * 2017-12-29 2019-02-12 珠海泰诺麦博生物技术有限公司 一种针对破伤风毒素的全人源单克隆中和抗体及其应用
CN108314730B (zh) * 2017-12-29 2019-01-08 珠海泰诺麦博生物技术有限公司 抗破伤风毒素中和抗体及其制备与应用
CN108218984B (zh) * 2017-12-29 2018-10-26 珠海泰诺麦博生物技术有限公司 一种抗破伤风毒素的全人源中和抗体
CN108623681B (zh) * 2018-05-04 2019-05-24 珠海泰诺麦博生物技术有限公司 一种抗破伤风毒素的中和抗体及应用

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