JP2021506922A5 - - Google Patents

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Publication number
JP2021506922A5
JP2021506922A5 JP2020534482A JP2020534482A JP2021506922A5 JP 2021506922 A5 JP2021506922 A5 JP 2021506922A5 JP 2020534482 A JP2020534482 A JP 2020534482A JP 2020534482 A JP2020534482 A JP 2020534482A JP 2021506922 A5 JP2021506922 A5 JP 2021506922A5
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Japan
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variable region
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heavy chain
light chain
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JP2020534482A
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Japanese (ja)
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JP2021506922A (ja
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Priority claimed from PCT/CN2018/122534 external-priority patent/WO2019120269A1/zh
Publication of JP2021506922A publication Critical patent/JP2021506922A/ja
Publication of JP2021506922A5 publication Critical patent/JP2021506922A5/ja
Pending legal-status Critical Current

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JP2020534482A 2017-12-22 2018-12-21 Lag−3抗体医薬組成物およびその使用 Pending JP2021506922A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201711408330 2017-12-22
CN201711408330.4 2017-12-22
PCT/CN2018/122534 WO2019120269A1 (zh) 2017-12-22 2018-12-21 Lag-3抗体药物组合物及其用途

Publications (2)

Publication Number Publication Date
JP2021506922A JP2021506922A (ja) 2021-02-22
JP2021506922A5 true JP2021506922A5 (https=) 2021-12-23

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ID=66993121

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Application Number Title Priority Date Filing Date
JP2020534482A Pending JP2021506922A (ja) 2017-12-22 2018-12-21 Lag−3抗体医薬組成物およびその使用

Country Status (11)

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US (1) US20220031842A1 (https=)
EP (1) EP3714901A4 (https=)
JP (1) JP2021506922A (https=)
KR (1) KR20200104314A (https=)
CN (1) CN111356476B (https=)
AU (1) AU2018391217A1 (https=)
BR (1) BR112020011664A2 (https=)
CA (1) CA3085656A1 (https=)
RU (1) RU2771384C2 (https=)
TW (1) TWI869334B (https=)
WO (1) WO2019120269A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN120241997A (zh) 2019-02-18 2025-07-04 伊莱利利公司 治疗性抗体制剂
CN110787292B (zh) * 2020-01-06 2020-04-24 上海复宏汉霖生物技术股份有限公司 一种细胞程序性死亡受体1抗体制剂及其用途
CN114504642B (zh) * 2020-11-17 2026-03-27 江苏奥赛康生物医药有限公司 一种含抗cldn18.2抗体的液体药物组合物
CN114617961B (zh) * 2020-12-10 2022-12-02 北京东方百泰生物科技股份有限公司 一种抗lag-3单克隆抗体的注射制剂
EP4403573A4 (en) * 2021-09-15 2024-12-25 Jiangsu Hengrui Pharmaceuticals Co., Ltd. PHARMACEUTICAL COMPOSITION CONTAINING BISPECIFIC ANTI-PVRIG/TIGIT ANTIBODY
JP2024536881A (ja) * 2021-09-29 2024-10-08 中山康方生物医▲藥▼有限公司 抗lag3抗体、医薬組成物、及び使用
CN114874324B (zh) * 2022-05-13 2023-02-03 苏州旭光科星抗体生物科技有限公司 一种检测可溶性lag-3蛋白含量的酶联免疫检测试剂盒及应用
CN121889167A (zh) * 2023-09-13 2026-04-17 正大天晴药业集团股份有限公司 包含抗pd-1抗体和第二抗体的药物组合物
CN117159703B (zh) * 2023-11-02 2024-04-02 正大天晴(广州)医药有限公司 含抗lag-3抗体的药物组合物及其用途
CN120754244B (zh) * 2025-09-10 2025-12-12 江苏豪森药业集团有限公司 一种含抗cd19抗体的药物组合物及其用途

Family Cites Families (18)

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Publication number Priority date Publication date Assignee Title
CA2189657C (fr) * 1994-05-06 2002-03-12 Florence Faure Fractions polypeptidiques solubles de la proteine lag-3; procede de production; composition therapeutique; anticorps anti-idiotype
US6267958B1 (en) * 1995-07-27 2001-07-31 Genentech, Inc. Protein formulation
US6171586B1 (en) * 1997-06-13 2001-01-09 Genentech, Inc. Antibody formulation
PL1897548T5 (pl) 2003-02-28 2025-03-17 The Johns Hopkins University Regulacja komórek T
EP1987839A1 (en) 2007-04-30 2008-11-05 I.N.S.E.R.M. Institut National de la Sante et de la Recherche Medicale Cytotoxic anti-LAG-3 monoclonal antibody and its use in the treatment or prevention of organ transplant rejection and autoimmune disease
AR072999A1 (es) * 2008-08-11 2010-10-06 Medarex Inc Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos
UY34887A (es) 2012-07-02 2013-12-31 Bristol Myers Squibb Company Una Corporacion Del Estado De Delaware Optimización de anticuerpos que se fijan al gen de activación de linfocitos 3 (lag-3) y sus usos
US10344088B2 (en) 2013-03-15 2019-07-09 Glaxosmithkline Intellectual Property Development Limited Antigen binding proteins
AU2014347004B2 (en) * 2013-11-05 2019-08-08 Bavarian Nordic A/S Combination therapy for treating cancer with a poxvirus expressing a tumor antigen and an antagonist and/or agonist of an immune checkpoint inhibitor
CN106061488B (zh) * 2013-12-02 2021-04-09 菲奥医药公司 癌症的免疫治疗
KR102442436B1 (ko) 2014-03-14 2022-09-15 노파르티스 아게 Lag-3에 대한 항체 분자 및 그의 용도
WO2015198312A1 (en) * 2014-06-24 2015-12-30 Ccam Therapeutics Ltd. Compositions comprising antibodies to ceacam-1 and lag-3 for cancer therapy
JO3663B1 (ar) * 2014-08-19 2020-08-27 Merck Sharp & Dohme الأجسام المضادة لمضاد lag3 وأجزاء ربط الأنتيجين
CN114853891A (zh) * 2015-07-22 2022-08-05 索伦托药业有限公司 与lag3结合的抗体治疗剂
CN117510633A (zh) * 2015-09-02 2024-02-06 伊缪泰普有限公司 抗lag-3抗体
RS61510B1 (sr) * 2016-05-18 2021-03-31 Boehringer Ingelheim Int Anti pd-1 i anti-lag3 antitela za lečenje kancera
US11155617B2 (en) * 2016-06-23 2021-10-26 Jiangsu Hengrui Medicine Co., Ltd. LAG-3 antibody, antigen-binding fragment thereof, and pharmaceutical application thereof
JP7382232B2 (ja) 2017-05-02 2023-11-16 メルク・シャープ・アンド・ドーム・エルエルシー 抗lag3抗体の製剤および抗lag3抗体と抗pd-1抗体との共製剤

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