JP2021505598A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2021505598A5 JP2021505598A5 JP2020530969A JP2020530969A JP2021505598A5 JP 2021505598 A5 JP2021505598 A5 JP 2021505598A5 JP 2020530969 A JP2020530969 A JP 2020530969A JP 2020530969 A JP2020530969 A JP 2020530969A JP 2021505598 A5 JP2021505598 A5 JP 2021505598A5
- Authority
- JP
- Japan
- Prior art keywords
- phenyl
- methyl
- dihydro
- pyridine
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 **N(CC1)CCC1(C1)OCC1NCC(COc1cccc(S(N(*)*)(=O)=O)c1)O Chemical compound **N(CC1)CCC1(C1)OCC1NCC(COc1cccc(S(N(*)*)(=O)=O)c1)O 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762595133P | 2017-12-06 | 2017-12-06 | |
| US62/595,133 | 2017-12-06 | ||
| PCT/US2018/064316 WO2019113359A1 (en) | 2017-12-06 | 2018-12-06 | Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021505598A JP2021505598A (ja) | 2021-02-18 |
| JP2021505598A5 true JP2021505598A5 (enExample) | 2022-01-11 |
| JP7357617B2 JP7357617B2 (ja) | 2023-10-06 |
Family
ID=64744985
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020530969A Active JP7357617B2 (ja) | 2017-12-06 | 2018-12-06 | 心不全およびそれに関連する障害の治療または予防に有用なβ－３アドレナリン受容体のモジュレーター |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US11339172B2 (enExample) |
| EP (1) | EP3720858B1 (enExample) |
| JP (1) | JP7357617B2 (enExample) |
| CN (1) | CN111699189B (enExample) |
| AR (1) | AR114156A1 (enExample) |
| ES (1) | ES2953576T3 (enExample) |
| MA (1) | MA51015A (enExample) |
| TW (1) | TWI822713B (enExample) |
| WO (1) | WO2019113359A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA44037B1 (fr) | 2016-06-06 | 2020-03-31 | Arena Pharm Inc | Modulateurs du récepteur adrénergique bêta 3 utile dans le traitement ou la prévention de troubles associés à ceux-ci |
| DK3448859T3 (da) | 2017-03-20 | 2019-09-23 | Forma Therapeutics Inc | Pyrrolopyrrolsammensætninger som pyruvatkinase- (pkr) aktivatorer |
| ES2953576T3 (es) * | 2017-12-06 | 2023-11-14 | Arena Pharm Inc | Moduladores del receptor beta-3 adrenérgico útiles para el tratamiento o la prevención de la insuficiencia cardíaca y los trastornos relacionados con la misma |
| WO2020061378A1 (en) | 2018-09-19 | 2020-03-26 | Forma Therapeutics, Inc. | Treating sickle cell disease with a pyruvate kinase r activating compound |
| JP7450610B2 (ja) | 2018-09-19 | 2024-03-15 | ノヴォ・ノルディスク・ヘルス・ケア・アーゲー | ピルビン酸キナーゼｒの活性化 |
| MX2022003254A (es) | 2019-09-19 | 2022-04-18 | Forma Therapeutics Inc | Composiciones activadoras de piruvato cinasa r (pkr). |
| US12128035B2 (en) | 2021-03-19 | 2024-10-29 | Novo Nordisk Health Care Ag | Activating pyruvate kinase R |
| JP2023024954A (ja) | 2021-08-09 | 2023-02-21 | アリーナ ファーマシューティカルズ， インコーポレイテッド | ベータ－３アドレナリン作動性受容体に関連する障害の処置または予防に有用なベータ－３アドレナリン作動性受容体のモジュレーター |
| WO2023026185A1 (en) | 2021-08-26 | 2023-03-02 | Arena Pharmaceuticals, Inc. | Modulators of the beta-3 adrenergic receptor for the treatment or prevention of renal cystic disease and cardiorenal syndrome |
| US20240409548A1 (en) | 2021-10-06 | 2024-12-12 | Arena Pharmaceuticals, Inc. | Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of disorders related thereto |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5451677A (en) * | 1993-02-09 | 1995-09-19 | Merck & Co., Inc. | Substituted phenyl sulfonamides as selective β 3 agonists for the treatment of diabetes and obesity |
| FR2755439B1 (fr) | 1996-11-05 | 1998-12-24 | Virbac Sa | Derives aryloxypropanolamines, leur procede de preparation et leurs applications |
| JP4782342B2 (ja) | 1999-12-17 | 2011-09-28 | サノフィ−アベンティス | フェノキシプロパノールアミン類、それらの製造方法およびそれらを含む医薬組成物 |
| SK4612003A3 (en) * | 2000-10-20 | 2004-06-08 | Pfizer Prod Inc | Alpha-aryl ethanolamines and their use as beta-3 adrenergic receptor agonists |
| EP1833480A2 (en) | 2004-11-30 | 2007-09-19 | Artesian Therapeutics, Inc. | Cardiotonic compounds with inhibitory activity against beta-adrenergic receptors and phosphodiesterase |
| CN106999465B (zh) | 2014-10-14 | 2020-08-14 | 斯科勒普特有限公司 | 身体塑形 |
| MA44037B1 (fr) | 2016-06-06 | 2020-03-31 | Arena Pharm Inc | Modulateurs du récepteur adrénergique bêta 3 utile dans le traitement ou la prévention de troubles associés à ceux-ci |
| ES2953576T3 (es) * | 2017-12-06 | 2023-11-14 | Arena Pharm Inc | Moduladores del receptor beta-3 adrenérgico útiles para el tratamiento o la prevención de la insuficiencia cardíaca y los trastornos relacionados con la misma |
-
2018
- 2018-12-06 ES ES18822236T patent/ES2953576T3/es active Active
- 2018-12-06 WO PCT/US2018/064316 patent/WO2019113359A1/en not_active Ceased
- 2018-12-06 MA MA051015A patent/MA51015A/fr unknown
- 2018-12-06 JP JP2020530969A patent/JP7357617B2/ja active Active
- 2018-12-06 TW TW107143855A patent/TWI822713B/zh active
- 2018-12-06 EP EP18822236.8A patent/EP3720858B1/en active Active
- 2018-12-06 AR ARP180103577A patent/AR114156A1/es unknown
- 2018-12-06 CN CN201880088219.8A patent/CN111699189B/zh active Active
- 2018-12-06 US US16/769,507 patent/US11339172B2/en active Active
-
2022
- 2022-04-22 US US17/726,807 patent/US11987588B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021505598A5 (enExample) | ||
| US20250059181A1 (en) | Tetrahydro-Pyrido-Pyrimidine Derivatives | |
| EP2549875B1 (en) | Soluble guanylate cyclase activators | |
| CA2486187C (en) | Kinase inhibitors | |
| US9181272B2 (en) | Aldosterone synthase inhibitors | |
| AU2012354094C1 (en) | Use of inhibitors of the activity or function of PI3K | |
| JP6373978B2 (ja) | イミダゾピロリジノン誘導体および疾患の処置におけるその使用 | |
| AU2018334290A1 (en) | Pyridazinones and methods of use thereof | |
| HRP20180413T1 (hr) | Inhibitori kinaza koji reguliraju signalne puteve u apoptozi | |
| AU2004226165A1 (en) | Pyrimidin-4-one derivatives and their use as p38 kinase modulators | |
| JP2013501002A (ja) | Ｓｙｋキナーゼ阻害剤としての化合物および組成物 | |
| CA2816594A1 (en) | Nampt and rock inhibitors | |
| MX2010013919A (es) | Derivados de pirrolopiridinil-pirimidin-2-il-amina. | |
| KR102768715B1 (ko) | 3-((헤테로-)아릴)-8-아미노-2-옥소-1,3-디아자-스파이로-[4.5]-데칸유도체 | |
| JP2021505598A (ja) | 心不全およびそれに関連する障害の治療または予防に有用なβ−３アドレナリン受容体のモジュレーター | |
| WO2024238574A1 (en) | Cdk inhibitor compounds | |
| TW202337457A (zh) | 新穎苯并咪唑吡啶衍生物 | |
| AU2014253493B2 (en) | Tetrahydro-pyrido-pyrimidine derivatives |