MA51015A - Modulateurs du récepteur adrénergique bêta 3 utile dans le traitement ou la prévention de l'insuffisance cardiaque et de troubles associés à celle-ci - Google Patents

Modulateurs du récepteur adrénergique bêta 3 utile dans le traitement ou la prévention de l'insuffisance cardiaque et de troubles associés à celle-ci

Info

Publication number
MA51015A
MA51015A MA051015A MA51015A MA51015A MA 51015 A MA51015 A MA 51015A MA 051015 A MA051015 A MA 051015A MA 51015 A MA51015 A MA 51015A MA 51015 A MA51015 A MA 51015A
Authority
MA
Morocco
Prior art keywords
beta
prevention
treatment
heart failure
adrenergic receptor
Prior art date
Application number
MA051015A
Other languages
English (en)
French (fr)
Inventor
Quyen-Quyen Thuy Do
Bryan Aubrey Kramer
Young-Jun Shin
Thuy-Anh Tran
Brett Ullman
Original Assignee
Arena Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arena Pharm Inc filed Critical Arena Pharm Inc
Publication of MA51015A publication Critical patent/MA51015A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • C07D491/044Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MA051015A 2017-12-06 2018-12-06 Modulateurs du récepteur adrénergique bêta 3 utile dans le traitement ou la prévention de l'insuffisance cardiaque et de troubles associés à celle-ci MA51015A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762595133P 2017-12-06 2017-12-06

Publications (1)

Publication Number Publication Date
MA51015A true MA51015A (fr) 2021-04-21

Family

ID=64744985

Family Applications (1)

Application Number Title Priority Date Filing Date
MA051015A MA51015A (fr) 2017-12-06 2018-12-06 Modulateurs du récepteur adrénergique bêta 3 utile dans le traitement ou la prévention de l'insuffisance cardiaque et de troubles associés à celle-ci

Country Status (9)

Country Link
US (2) US11339172B2 (enExample)
EP (1) EP3720858B1 (enExample)
JP (1) JP7357617B2 (enExample)
CN (1) CN111699189B (enExample)
AR (1) AR114156A1 (enExample)
ES (1) ES2953576T3 (enExample)
MA (1) MA51015A (enExample)
TW (1) TWI822713B (enExample)
WO (1) WO2019113359A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA44037B1 (fr) * 2016-06-06 2020-03-31 Arena Pharm Inc Modulateurs du récepteur adrénergique bêta 3 utile dans le traitement ou la prévention de troubles associés à ceux-ci
US11014927B2 (en) 2017-03-20 2021-05-25 Forma Therapeutics, Inc. Pyrrolopyrrole compositions as pyruvate kinase (PKR) activators
TWI822713B (zh) * 2017-12-06 2023-11-21 美商艾尼納製藥公司 適用於治療或預防與其相關之病症之β-3腎上腺素受體的調節劑
US12053458B2 (en) 2018-09-19 2024-08-06 Novo Nordisk Health Care Ag Treating sickle cell disease with a pyruvate kinase R activating compound
ES2989438T3 (es) 2018-09-19 2024-11-26 Novo Nordisk Healthcare Ag Activación de la piruvato cinasa R
EP4031132A4 (en) 2019-09-19 2023-09-13 Forma Therapeutics, Inc. Activating pyruvate kinase r
US12128035B2 (en) 2021-03-19 2024-10-29 Novo Nordisk Health Care Ag Activating pyruvate kinase R
WO2023017388A1 (en) * 2021-08-09 2023-02-16 Arena Pharmaceuticals, Inc. Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure
WO2023026185A1 (en) * 2021-08-26 2023-03-02 Arena Pharmaceuticals, Inc. Modulators of the beta-3 adrenergic receptor for the treatment or prevention of renal cystic disease and cardiorenal syndrome
US20240409548A1 (en) 2021-10-06 2024-12-12 Arena Pharmaceuticals, Inc. Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of disorders related thereto

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5451677A (en) * 1993-02-09 1995-09-19 Merck & Co., Inc. Substituted phenyl sulfonamides as selective β 3 agonists for the treatment of diabetes and obesity
FR2755439B1 (fr) 1996-11-05 1998-12-24 Virbac Sa Derives aryloxypropanolamines, leur procede de preparation et leurs applications
DE60033964T2 (de) 1999-12-17 2007-11-29 Sanofi-Aventis Phenoxypropanolamin-derivate, ihre herstellung und therapeutische verwendung
AP2001002307A0 (en) * 2000-10-20 2001-12-31 Pfizer Prod Inc B3 adrenergic receptor agonists and uses thereof.
US20080255134A1 (en) 2004-11-30 2008-10-16 Artesian Therapeutics, Inc. Cardiotonic Compounds With Inhibitory Activity Against Beta-Adrenergic Receptors And Phosphodiesterase
CN106999465B (zh) 2014-10-14 2020-08-14 斯科勒普特有限公司 身体塑形
MA44037B1 (fr) 2016-06-06 2020-03-31 Arena Pharm Inc Modulateurs du récepteur adrénergique bêta 3 utile dans le traitement ou la prévention de troubles associés à ceux-ci
TWI822713B (zh) * 2017-12-06 2023-11-21 美商艾尼納製藥公司 適用於治療或預防與其相關之病症之β-3腎上腺素受體的調節劑

Also Published As

Publication number Publication date
US20220396579A1 (en) 2022-12-15
TWI822713B (zh) 2023-11-21
EP3720858A1 (en) 2020-10-14
US11339172B2 (en) 2022-05-24
CN111699189B (zh) 2025-02-18
TW201925206A (zh) 2019-07-01
WO2019113359A1 (en) 2019-06-13
EP3720858C0 (en) 2023-06-07
CN111699189A (zh) 2020-09-22
US20200385395A1 (en) 2020-12-10
ES2953576T3 (es) 2023-11-14
JP2021505598A (ja) 2021-02-18
US11987588B2 (en) 2024-05-21
JP7357617B2 (ja) 2023-10-06
AR114156A1 (es) 2020-07-29
EP3720858B1 (en) 2023-06-07

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