|
US3896111A
(en)
|
1973-02-20 |
1975-07-22 |
Research Corp |
Ansa macrolides
|
|
US4151042A
(en)
|
1977-03-31 |
1979-04-24 |
Takeda Chemical Industries, Ltd. |
Method for producing maytansinol and its derivatives
|
|
US4137230A
(en)
|
1977-11-14 |
1979-01-30 |
Takeda Chemical Industries, Ltd. |
Method for the production of maytansinoids
|
|
US4265814A
(en)
|
1978-03-24 |
1981-05-05 |
Takeda Chemical Industries |
Matansinol 3-n-hexadecanoate
|
|
US4307016A
(en)
|
1978-03-24 |
1981-12-22 |
Takeda Chemical Industries, Ltd. |
Demethyl maytansinoids
|
|
JPS5562090A
(en)
|
1978-10-27 |
1980-05-10 |
Takeda Chem Ind Ltd |
Novel maytansinoid compound and its preparation
|
|
JPS5566585A
(en)
|
1978-11-14 |
1980-05-20 |
Takeda Chem Ind Ltd |
Novel maytansinoid compound and its preparation
|
|
US4256746A
(en)
|
1978-11-14 |
1981-03-17 |
Takeda Chemical Industries |
Dechloromaytansinoids, their pharmaceutical compositions and method of use
|
|
JPS55164687A
(en)
|
1979-06-11 |
1980-12-22 |
Takeda Chem Ind Ltd |
Novel maytansinoid compound and its preparation
|
|
JPS55102583A
(en)
|
1979-01-31 |
1980-08-05 |
Takeda Chem Ind Ltd |
20-acyloxy-20-demethylmaytansinoid compound
|
|
US4657760A
(en)
|
1979-03-20 |
1987-04-14 |
Ortho Pharmaceutical Corporation |
Methods and compositions using monoclonal antibody to human T cells
|
|
US4515894A
(en)
|
1979-03-20 |
1985-05-07 |
Ortho Pharmaceutical Corporation |
Hybrid cell line for producing monoclonal antibody to human T cells
|
|
US4363799A
(en)
|
1979-03-20 |
1982-12-14 |
Ortho Pharmaceutical Corporation |
Monoclonal antibody to human T cells, and methods for preparing same
|
|
JPS55162791A
(en)
|
1979-06-05 |
1980-12-18 |
Takeda Chem Ind Ltd |
Antibiotic c-15003pnd and its preparation
|
|
JPS55164685A
(en)
|
1979-06-08 |
1980-12-22 |
Takeda Chem Ind Ltd |
Novel maytansinoid compound and its preparation
|
|
JPS55164686A
(en)
|
1979-06-11 |
1980-12-22 |
Takeda Chem Ind Ltd |
Novel maytansinoid compound and its preparation
|
|
US4309428A
(en)
|
1979-07-30 |
1982-01-05 |
Takeda Chemical Industries, Ltd. |
Maytansinoids
|
|
JPS5645483A
(en)
|
1979-09-19 |
1981-04-25 |
Takeda Chem Ind Ltd |
C-15003phm and its preparation
|
|
EP0028683A1
(en)
|
1979-09-21 |
1981-05-20 |
Takeda Chemical Industries, Ltd. |
Antibiotic C-15003 PHO and production thereof
|
|
JPS5645485A
(en)
|
1979-09-21 |
1981-04-25 |
Takeda Chem Ind Ltd |
Production of c-15003pnd
|
|
US4675386A
(en)
|
1979-11-27 |
1987-06-23 |
Regents Of The University Of California |
Monoclonal antibody methods and compositions specific for single antigens in antigen aggregates
|
|
WO1982001188A1
(en)
|
1980-10-08 |
1982-04-15 |
Takeda Chemical Industries Ltd |
4,5-deoxymaytansinoide compounds and process for preparing same
|
|
US4450254A
(en)
|
1980-11-03 |
1984-05-22 |
Standard Oil Company |
Impact improvement of high nitrile resins
|
|
US4313946A
(en)
|
1981-01-27 |
1982-02-02 |
The United States Of America As Represented By The Secretary Of Agriculture |
Chemotherapeutically active maytansinoids from Trewia nudiflora
|
|
US4315929A
(en)
|
1981-01-27 |
1982-02-16 |
The United States Of America As Represented By The Secretary Of Agriculture |
Method of controlling the European corn borer with trewiasine
|
|
JPS57192389A
(en)
|
1981-05-20 |
1982-11-26 |
Takeda Chem Ind Ltd |
Novel maytansinoid
|
|
US4880935A
(en)
|
1986-07-11 |
1989-11-14 |
Icrf (Patents) Limited |
Heterobifunctional linking agents derived from N-succinimido-dithio-alpha methyl-methylene-benzoates
|
|
ATE114723T1
(de)
|
1987-03-02 |
1994-12-15 |
Enzon Lab Inc |
Organismus als träger für ''single chain antibody domain (scad)''.
|
|
US5606040A
(en)
|
1987-10-30 |
1997-02-25 |
American Cyanamid Company |
Antitumor and antibacterial substituted disulfide derivatives prepared from compounds possessing a methyl-trithio group
|
|
US5770701A
(en)
|
1987-10-30 |
1998-06-23 |
American Cyanamid Company |
Process for preparing targeted forms of methyltrithio antitumor agents
|
|
AU633251B2
(en)
|
1988-02-03 |
1993-01-28 |
Xoma Corporation |
Therapeutic use of anti-t cell immunotoxin for autoimmune diseases
|
|
IL106992A
(en)
|
1988-02-11 |
1994-06-24 |
Bristol Myers Squibb Co |
Acylhydrazone derivatives of anthracycline and methods for their preparation
|
|
US6010902A
(en)
|
1988-04-04 |
2000-01-04 |
Bristol-Meyers Squibb Company |
Antibody heteroconjugates and bispecific antibodies for use in regulation of lymphocyte activity
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5413923A
(en)
|
1989-07-25 |
1995-05-09 |
Cell Genesys, Inc. |
Homologous recombination for universal donor cells and chimeric mammalian hosts
|
|
CA2026147C
(en)
|
1989-10-25 |
2006-02-07 |
Ravi J. Chari |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
|
US5208020A
(en)
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
|
DE69120146T2
(de)
|
1990-01-12 |
1996-12-12 |
Cell Genesys Inc |
Erzeugung xenogener antikörper
|
|
WO1996033735A1
(en)
|
1995-04-27 |
1996-10-31 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
ATE158021T1
(de)
|
1990-08-29 |
1997-09-15 |
Genpharm Int |
Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
IT1249051B
(it)
*
|
1991-02-26 |
1995-02-11 |
Italfarmaco Spa |
Immunotossina da anticorpi monoclonali anti-cd5
|
|
AU1771192A
(en)
|
1991-03-12 |
1992-10-21 |
Biogen, Inc. |
Monoclonal antibodies recognizing lymphocyte function associated antigen-3
|
|
WO1994004679A1
(en)
|
1991-06-14 |
1994-03-03 |
Genentech, Inc. |
Method for making humanized antibodies
|
|
US7018809B1
(en)
|
1991-09-19 |
2006-03-28 |
Genentech, Inc. |
Expression of functional antibody fragments
|
|
US6764681B2
(en)
|
1991-10-07 |
2004-07-20 |
Biogen, Inc. |
Method of prophylaxis or treatment of antigen presenting cell driven skin conditions using inhibitors of the CD2/LFA-3 interaction
|
|
US6162432A
(en)
|
1991-10-07 |
2000-12-19 |
Biogen, Inc. |
Method of prophylaxis or treatment of antigen presenting cell driven skin conditions using inhibitors of the CD2/LFA-3 interaction
|
|
US5837491A
(en)
|
1991-11-04 |
1998-11-17 |
Xoma Corporation |
Polynucleotides encoding gelonin sequences
|
|
US6146850A
(en)
|
1991-11-04 |
2000-11-14 |
Xoma Corporation |
Proteins encoding gelonin sequences
|
|
US5621083A
(en)
|
1991-11-04 |
1997-04-15 |
Xoma Corporation |
Immunotoxins comprising ribosome-inactivating proteins
|
|
PT1024191E
(pt)
|
1991-12-02 |
2008-12-22 |
Medical Res Council |
Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos
|
|
US5869619A
(en)
*
|
1991-12-13 |
1999-02-09 |
Xoma Corporation |
Modified antibody variable domains
|
|
EP0571613B1
(en)
|
1991-12-13 |
2003-09-17 |
Xoma Corporation |
Methods and materials for preparation of modified antibody variable domains and therapeutic uses thereof
|
|
US5622929A
(en)
|
1992-01-23 |
1997-04-22 |
Bristol-Myers Squibb Company |
Thioether conjugates
|
|
EP0563475B1
(en)
|
1992-03-25 |
2000-05-31 |
Immunogen Inc |
Cell binding agent conjugates of derivatives of CC-1065
|
|
US5635483A
(en)
|
1992-12-03 |
1997-06-03 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Tumor inhibiting tetrapeptide bearing modified phenethyl amides
|
|
US5780588A
(en)
|
1993-01-26 |
1998-07-14 |
Arizona Board Of Regents |
Elucidation and synthesis of selected pentapeptides
|
|
ES2164699T3
(es)
|
1993-03-05 |
2002-03-01 |
Univ Catholique Louvain |
Anticuerpo lo-cd2a y usos del mismo para inhibir la activacion y la proliferacion de las celulas t.
|
|
US5951983A
(en)
|
1993-03-05 |
1999-09-14 |
Universite Catholique De Louvain |
Methods of inhibiting T cell mediated immune responses with humanized LO-CD2A-specific antibodies
|
|
US5817311A
(en)
|
1993-03-05 |
1998-10-06 |
Universite Catholique De Louvain |
Methods of inhibiting T-cell medicated immune responses with LO-CD2a-specific antibodies
|
|
US5730979A
(en)
|
1993-03-05 |
1998-03-24 |
Universite Catholique Delouvain |
LO-CD2a antibody and uses thereof for inhibiting T cell activation and proliferation
|
|
US7592006B1
(en)
|
1993-03-05 |
2009-09-22 |
Université Catholique de Louvain |
Composition comprising the LO-CD2a antibody
|
|
DE4312916C2
(de)
|
1993-04-14 |
1995-03-23 |
Fresenius Ag |
Arzneimittel zur Behandlung von Immunreaktionen
|
|
US6214345B1
(en)
|
1993-05-14 |
2001-04-10 |
Bristol-Myers Squibb Co. |
Lysosomal enzyme-cleavable antitumor drug conjugates
|
|
US5795572A
(en)
|
1993-05-25 |
1998-08-18 |
Bristol-Myers Squibb Company |
Monoclonal antibodies and FV specific for CD2 antigen
|
|
EP0647450A1
(en)
|
1993-09-09 |
1995-04-12 |
BEHRINGWERKE Aktiengesellschaft |
Improved prodrugs for enzyme mediated activation
|
|
ES2153895T3
(es)
|
1994-03-08 |
2001-03-16 |
Dana Farber Cancer Inst Inc |
Metodos para modular la insensibilidad de celulas t.
|
|
US5773001A
(en)
|
1994-06-03 |
1998-06-30 |
American Cyanamid Company |
Conjugates of methyltrithio antitumor agents and intermediates for their synthesis
|
|
US5789199A
(en)
|
1994-11-03 |
1998-08-04 |
Genentech, Inc. |
Process for bacterial production of polypeptides
|
|
US5663149A
(en)
|
1994-12-13 |
1997-09-02 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Human cancer inhibitory pentapeptide heterocyclic and halophenyl amides
|
|
US5840523A
(en)
|
1995-03-01 |
1998-11-24 |
Genetech, Inc. |
Methods and compositions for secretion of heterologous polypeptides
|
|
WO1996034096A1
(en)
|
1995-04-28 |
1996-10-31 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
AU5981796A
(en)
|
1995-06-07 |
1997-01-09 |
Thera Pro |
Pyrularia thionin containing immunotoxins and immunotoxin-li ke conjugates
|
|
US5714586A
(en)
|
1995-06-07 |
1998-02-03 |
American Cyanamid Company |
Methods for the preparation of monomeric calicheamicin derivative/carrier conjugates
|
|
US5712374A
(en)
|
1995-06-07 |
1998-01-27 |
American Cyanamid Company |
Method for the preparation of substantiallly monomeric calicheamicin derivative/carrier conjugates
|
|
DK0871490T3
(da)
|
1995-12-22 |
2003-07-07 |
Bristol Myers Squibb Co |
Forgrenede hydrazonlinkere
|
|
US6218519B1
(en)
|
1996-04-12 |
2001-04-17 |
Pro-Neuron, Inc. |
Compounds and methods for the selective treatment of cancer and bacterial infections
|
|
US6764688B2
(en)
|
1996-09-03 |
2004-07-20 |
Kaneka Corporation |
Method for inducing immunosuppressive cells and a culture device to be used therefor
|
|
WO1998013059A1
(en)
|
1996-09-27 |
1998-04-02 |
Bristol-Myers Squibb Company |
Hydrolyzable prodrugs for delivery of anticancer drugs to metastatic cells
|
|
US5916771A
(en)
|
1996-10-11 |
1999-06-29 |
Abgenix, Inc. |
Production of a multimeric protein by cell fusion method
|
|
US6759509B1
(en)
|
1996-11-05 |
2004-07-06 |
Bristol-Myers Squibb Company |
Branched peptide linkers
|
|
CA2722378C
(en)
|
1996-12-03 |
2015-02-03 |
Amgen Fremont Inc. |
Human antibodies that bind tnf.alpha.
|
|
US6849258B1
(en)
|
1997-07-18 |
2005-02-01 |
Universite Catholique De Louvain |
LO-CD2a antibody and uses thereof for inhibiting T cell activation and proliferation
|
|
US6358506B1
(en)
|
1997-11-05 |
2002-03-19 |
University Of Southern California |
Use of cytokines and mitogens to inhibit pathological immune responses
|
|
AU1585799A
(en)
|
1997-11-14 |
1999-06-07 |
General Hospital Corporation, The |
Treatment of hematologic disorders
|
|
US20060051355A1
(en)
|
1998-03-23 |
2006-03-09 |
Van Oosterhout Ypke V |
Methods and means for the treatment of immune-related diseases
|
|
EA003398B1
(ru)
|
1998-05-22 |
2003-04-24 |
Дайити Фармасьютикал Ко., Лтд. |
Лекарственный комплекс c полимерным носителем
|
|
US7157418B1
(en)
|
1998-07-22 |
2007-01-02 |
Osprey Pharmaceuticals, Ltd. |
Methods and compositions for treating secondary tissue damage and other inflammatory conditions and disorders
|
|
WO2000045842A2
(en)
|
1999-02-04 |
2000-08-10 |
The General Hospital Corporation |
Methods for human allografting
|
|
US6268488B1
(en)
|
1999-05-25 |
2001-07-31 |
Barbas, Iii Carlos F. |
Prodrug activation using catalytic antibodies
|
|
US6541611B1
(en)
|
1999-06-18 |
2003-04-01 |
Universite Catholique De Louvain |
LO-CD2b antibody
|
|
US20040052793A1
(en)
|
2001-02-22 |
2004-03-18 |
Carter Paul J. |
Caspase activivated prodrugs therapy
|
|
US6333410B1
(en)
|
2000-08-18 |
2001-12-25 |
Immunogen, Inc. |
Process for the preparation and purification of thiol-containing maytansinoids
|
|
US20040018194A1
(en)
|
2000-11-28 |
2004-01-29 |
Francisco Joseph A. |
Recombinant anti-CD30 antibodies and uses thereof
|
|
AU2002250236A1
(en)
|
2001-03-02 |
2002-09-19 |
Medimmune, Inc. |
Cd2 antagonists for treatment of autoimmune or inflammatory disease
|
|
EP1243276A1
(en)
|
2001-03-23 |
2002-09-25 |
Franciscus Marinus Hendrikus De Groot |
Elongated and multiple spacers containing activatible prodrugs
|
|
US6884869B2
(en)
|
2001-04-30 |
2005-04-26 |
Seattle Genetics, Inc. |
Pentapeptide compounds and uses related thereto
|
|
US6441163B1
(en)
|
2001-05-31 |
2002-08-27 |
Immunogen, Inc. |
Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents
|
|
US7091186B2
(en)
|
2001-09-24 |
2006-08-15 |
Seattle Genetics, Inc. |
p-Amidobenzylethers in drug delivery agents
|
|
US6716821B2
(en)
|
2001-12-21 |
2004-04-06 |
Immunogen Inc. |
Cytotoxic agents bearing a reactive polyethylene glycol moiety, cytotoxic conjugates comprising polyethylene glycol linking groups, and methods of making and using the same
|
|
US20080254027A1
(en)
*
|
2002-03-01 |
2008-10-16 |
Bernett Matthew J |
Optimized CD5 antibodies and methods of using the same
|
|
US20050180972A1
(en)
|
2002-07-31 |
2005-08-18 |
Wahl Alan F. |
Anti-CD20 antibody-drug conjugates for the treatment of cancer and immune disorders
|
|
WO2004022097A1
(en)
|
2002-09-05 |
2004-03-18 |
Medimmune, Inc. |
Methods of preventing or treating cell malignancies by administering cd2 antagonists
|
|
US8088387B2
(en)
|
2003-10-10 |
2012-01-03 |
Immunogen Inc. |
Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
|
|
US7276497B2
(en)
|
2003-05-20 |
2007-10-02 |
Immunogen Inc. |
Cytotoxic agents comprising new maytansinoids
|
|
TW200521231A
(en)
|
2003-09-18 |
2005-07-01 |
Novartis Ag |
Therapeutic binding molecules
|
|
EP2478912B1
(en)
|
2003-11-06 |
2016-08-31 |
Seattle Genetics, Inc. |
Auristatin conjugates with anti-HER2 or anti-CD22 antibodies and their use in therapy
|
|
CA2556752C
(en)
|
2004-02-23 |
2016-02-02 |
Genentech, Inc. |
Heterocyclic self-immolative linkers and conjugates
|
|
DK1791565T3
(en)
|
2004-09-23 |
2016-08-01 |
Genentech Inc |
Cysteingensplejsede antibodies and conjugates
|
|
EP1661584A1
(en)
|
2004-11-26 |
2006-05-31 |
Heinz Dr. Faulstich |
Use of conjugates of amatoxins and phallotoxins with macromolecules for cancer and inflammation therapy
|
|
ES2371085T3
(es)
|
2006-05-27 |
2011-12-27 |
Faulstich, Heinz, Dr. |
Utilización de conjugados de amatoxinas o falotoxinas con macromoléculas para la terapia tumoral y de la inflamación.
|
|
WO2008067115A2
(en)
|
2006-11-03 |
2008-06-05 |
The Board Of Trustees Of The Leland Stanford Junior University |
Selective immunodepletion of endogenous stem cell niche for engraftment
|
|
WO2008121160A2
(en)
*
|
2006-11-21 |
2008-10-09 |
Xencor, Inc. |
Optimized antibodies that target cd5
|
|
ITBO20070242A1
(it)
|
2007-04-03 |
2008-10-04 |
Gsg Int Spa |
Profilato per serramenti scorrevoli, metodo per la realizzazione del profilato, e serramento ottenuto con il profilato stesso.
|
|
NZ610239A
(en)
|
2008-04-30 |
2014-11-28 |
Immunogen Inc |
Cross-linkers and their uses
|
|
RU2011111640A
(ru)
|
2008-08-29 |
2012-10-10 |
Симфоген А/С (Dk) |
Антитела против cd5
|
|
AU2010234335A1
(en)
|
2009-04-08 |
2011-10-13 |
Deutsches Krebsforschungszentrum |
Amatoxin-armed target-binding moieties for the treatment of cancer
|
|
ES2784829T3
(es)
|
2009-04-08 |
2020-10-01 |
Faulstich Heinz Dr |
Componentes de unión a la superficie de células terapéuticas provistos de amatoxina diseñados para terapia de tumores
|
|
WO2010145895A1
(en)
|
2009-05-14 |
2010-12-23 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Compositions containing antibodies for treating cd5+ hla-dr+ b or t cell related diseases
|
|
US20120045435A1
(en)
*
|
2010-08-18 |
2012-02-23 |
Theresa Deisher |
Compositions and methods to inhibit stem cell and progenitor cell binding to lymphoid tissue and for regenerating germinal centers in lymphatic tissues
|
|
JP2013540731A
(ja)
|
2010-09-08 |
2013-11-07 |
イェダ リサーチ アンド デベロップメント カンパニー リミテッド |
安定かつ長期間の生着のための免疫抑制薬物組合せ
|
|
ES2402254T3
(es)
|
2010-09-30 |
2013-04-30 |
Heidelberg Pharma Ag |
Conjugados de amatoxinas con ligadores mejorados
|
|
EP2497499A1
(en)
|
2011-03-10 |
2012-09-12 |
Heidelberg Pharma GmbH |
Amatoxin-conjugates with improved linkages
|
|
JP2015504047A
(ja)
|
2011-12-22 |
2015-02-05 |
イェダ リサーチ アンド デベロップメント カンパニー リミテッド |
安定かつ長期の生着のための併用療法
|
|
WO2013116307A1
(en)
*
|
2012-01-30 |
2013-08-08 |
Mount Sinai School Of Medicine |
Method for programming differentiated cells into hematopoietic stem cells
|
|
US20130280282A1
(en)
|
2012-04-24 |
2013-10-24 |
Daiichi Sankyo Co., Ltd. |
Dr5 ligand drug conjugates
|
|
US9504756B2
(en)
|
2012-05-15 |
2016-11-29 |
Seattle Genetics, Inc. |
Self-stabilizing linker conjugates
|
|
EP2684865A1
(en)
|
2012-07-13 |
2014-01-15 |
Heidelberg Pharma GmbH |
Methods for synthesizing amatoxin building block and amatoxins
|
|
US20150218220A1
(en)
|
2012-09-12 |
2015-08-06 |
Brian Alan MENDELSOHN |
Amatoxin derivatives and cell-permeable conjugates thereof as inhibitors of rna polymerase
|
|
ES2732574T3
(es)
|
2012-11-30 |
2019-11-25 |
Novartis Ag |
Métodos para preparar conjugados a partir de proteínas que contienen disulfuro
|
|
KR102503695B1
(ko)
|
2013-02-28 |
2023-02-23 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
줄기세포를 동원하기 위한 방법 및 조성물
|
|
EP2774624A1
(en)
|
2013-03-04 |
2014-09-10 |
Heidelberg Pharma GmbH |
Amatoxin derivatives
|
|
EP2968591A1
(en)
|
2013-03-15 |
2016-01-20 |
Novartis AG |
Cell proliferation inhibitors and conjugates thereof
|
|
KR102442906B1
(ko)
|
2013-12-19 |
2022-09-14 |
씨젠 인크. |
표적화된-약물 컨쥬게이트와 함께 사용되는 메틸렌 카바메이트 링커
|
|
EP3145542A4
(en)
|
2014-05-20 |
2018-01-17 |
ImmunoGen, Inc. |
Methods for characterizing and treating acute myeloid leukemia
|
|
CN107106701B
(zh)
|
2014-10-03 |
2020-11-06 |
西纳福克斯股份有限公司 |
磺酰胺接头、其缀合物及制备方法
|
|
EP3215519A1
(en)
*
|
2014-11-06 |
2017-09-13 |
Novartis AG |
Amatoxin derivatives and conjugates thereof as inhibitors of rna polymerase
|
|
EP3268047B9
(en)
|
2015-03-09 |
2024-01-10 |
Heidelberg Pharma Research GmbH |
Amatoxin-antibody conjugates
|
|
HK1256681A1
(zh)
|
2015-04-06 |
2019-10-04 |
President And Fellows Of Harvard College |
用於非清髓性预处理的组合物和方法
|
|
US10786549B2
(en)
|
2015-04-23 |
2020-09-29 |
Baylor College Of Medicine |
CD5 chimeric antigen receptor for adoptive T cell therapy
|
|
AU2016285552B2
(en)
|
2015-06-29 |
2022-10-13 |
Immunogen, Inc. |
Anti-CD123 antibodies and conjugates and derivatives thereof
|
|
US20170129128A1
(en)
|
2015-11-05 |
2017-05-11 |
Black & Decker Inc. |
Saw
|
|
MX378847B
(es)
|
2015-11-27 |
2025-03-11 |
Heidelberg Pharma Res Gmbh |
Nuevos derivados de gamma-amanitina
|
|
EP3222292A1
(en)
|
2016-03-03 |
2017-09-27 |
Heidelberg Pharma GmbH |
Amanitin conjugates
|
|
BR112018071465A2
(pt)
|
2016-04-20 |
2019-02-05 |
Hangzhou Dac Biotech Co Ltd |
derivados de toxinas de amanita e sua conjugação a uma molécula de ligação celular
|
|
WO2017191579A1
(en)
|
2016-05-05 |
2017-11-09 |
Novartis Ag |
Amatoxin derivatives and conjugates thereof as inhibitors of rna polymerase
|
|
IL263744B2
(en)
|
2016-06-17 |
2023-11-01 |
Magenta Therapeutics Inc |
Compositions and methods for the depletion of cd117 plus cells
|
|
CN109641051A
(zh)
|
2016-06-17 |
2019-04-16 |
美真达治疗公司 |
用于耗尽细胞的组合物和方法
|
|
RU2755728C2
(ru)
|
2016-12-23 |
2021-09-20 |
Хайдельберг Фарма Ресёрч Гмбх |
Новый конъюгат аманитина
|
|
EP3571230A4
(en)
|
2017-01-20 |
2020-12-16 |
Magenta Therapeutics, Inc. |
COMPOSITIONS AND METHODS FOR DELETION OF CD137 + CELLS
|
|
CA3065126A1
(en)
|
2017-06-01 |
2018-12-06 |
Innovative Cellular Therapeutics CO., LTD. |
Chimeric antigen receptor cell preparation and uses thereof
|
|
CN110997676B
(zh)
|
2017-08-07 |
2022-12-20 |
海德堡医药研究有限责任公司 |
合成鹅膏蕈碱的新方法
|
|
KR20200069364A
(ko)
|
2017-10-24 |
2020-06-16 |
마젠타 테라퓨틱스 인코포레이티드 |
Cd117+ 세포의 고갈을 위한 조성물 및 방법
|
|
CN119857155A
(zh)
|
2017-11-29 |
2025-04-22 |
海德堡医药研究有限责任公司 |
用于耗尽cd5+细胞的组合物和方法
|
|
US10869888B2
(en)
|
2018-04-17 |
2020-12-22 |
Innovative Cellular Therapeutics CO., LTD. |
Modified cell expansion and uses thereof
|
|
CA3107383A1
(en)
|
2018-07-23 |
2020-01-30 |
Magenta Therapeutics, Inc. |
Use of anti-cd5 antibody drug conjugate (adc) in allogeneic cell therapy
|