JP2017048208A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017048208A5 JP2017048208A5 JP2016206756A JP2016206756A JP2017048208A5 JP 2017048208 A5 JP2017048208 A5 JP 2017048208A5 JP 2016206756 A JP2016206756 A JP 2016206756A JP 2016206756 A JP2016206756 A JP 2016206756A JP 2017048208 A5 JP2017048208 A5 JP 2017048208A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- sequence
- region
- combination
- gisgdsntyyadsvkg
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38661910P | 2010-09-27 | 2010-09-27 | |
| EP10180485 | 2010-09-27 | ||
| EP10180485.4 | 2010-09-27 | ||
| US61/386,619 | 2010-09-27 | ||
| US201161437696P | 2011-01-31 | 2011-01-31 | |
| US61/437,696 | 2011-01-31 | ||
| US201161468607P | 2011-03-29 | 2011-03-29 | |
| US61/468,607 | 2011-03-29 | ||
| US201161486814P | 2011-05-17 | 2011-05-17 | |
| US61/486,814 | 2011-05-17 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013529669A Division JP6087283B2 (ja) | 2010-09-27 | 2011-09-26 | 多発性骨髄腫およびｎｈｌ治療用の抗ｃｄ３８抗体およびレナリドミドまたはボルテゾミブ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017048208A JP2017048208A (ja) | 2017-03-09 |
| JP2017048208A5 true JP2017048208A5 (https=) | 2017-07-20 |
| JP6231642B2 JP6231642B2 (ja) | 2017-11-15 |
Family
ID=43640677
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013529669A Expired - Fee Related JP6087283B2 (ja) | 2010-09-27 | 2011-09-26 | 多発性骨髄腫およびｎｈｌ治療用の抗ｃｄ３８抗体およびレナリドミドまたはボルテゾミブ |
| JP2016206756A Active JP6231642B2 (ja) | 2010-09-27 | 2016-10-21 | 多発性骨髄腫およびｎｈｌ治療用の抗ｃｄ３８抗体およびレナリドミドまたはボルテゾミブ |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013529669A Expired - Fee Related JP6087283B2 (ja) | 2010-09-27 | 2011-09-26 | 多発性骨髄腫およびｎｈｌ治療用の抗ｃｄ３８抗体およびレナリドミドまたはボルテゾミブ |
Country Status (22)
| Country | Link |
|---|---|
| US (4) | US8877899B2 (https=) |
| EP (1) | EP2621531B8 (https=) |
| JP (2) | JP6087283B2 (https=) |
| KR (1) | KR101912957B1 (https=) |
| CN (1) | CN103118706B (https=) |
| AU (1) | AU2011310696B2 (https=) |
| BR (1) | BR112013006769B1 (https=) |
| CA (1) | CA2812631C (https=) |
| DK (1) | DK2621531T3 (https=) |
| ES (1) | ES2617446T3 (https=) |
| HU (1) | HUE031956T2 (https=) |
| IL (1) | IL224915A (https=) |
| LT (1) | LT2621531T (https=) |
| MX (1) | MX350540B (https=) |
| NZ (1) | NZ607473A (https=) |
| PL (1) | PL2621531T3 (https=) |
| PT (1) | PT2621531T (https=) |
| RU (1) | RU2595839C2 (https=) |
| SG (1) | SG188345A1 (https=) |
| SI (1) | SI2621531T1 (https=) |
| WO (1) | WO2012041800A1 (https=) |
| ZA (1) | ZA201301232B (https=) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2860192B1 (en) | 2005-10-12 | 2017-09-27 | MorphoSys AG | Generation and profiling of fully human HuCAL GOLD-derived therapeutic antibodies specific for human CD38 |
| EP1914242A1 (en) * | 2006-10-19 | 2008-04-23 | Sanofi-Aventis | Novel anti-CD38 antibodies for the treatment of cancer |
| SI2621531T1 (sl) | 2010-09-27 | 2017-06-30 | Morphosys Ag | Anti-cd38 protitelo in lenalidomid ali bortezomib za zdravljenje multiplega mieloma in nhl |
| UA112170C2 (uk) * | 2010-12-10 | 2016-08-10 | Санофі | Протипухлинна комбінація, що містить антитіло, яке специфічно розпізнає cd38, і бортезоміб |
| JOP20210044A1 (ar) | 2010-12-30 | 2017-06-16 | Takeda Pharmaceuticals Co | الأجسام المضادة لـ cd38 |
| SG10201603411WA (en) | 2011-10-28 | 2016-07-28 | Teva Pharmaceuticals Australia Pty Ltd | Polypeptide constructs and uses thereof |
| JP6426093B2 (ja) | 2012-09-25 | 2018-11-28 | モルフォシス・アーゲー | 組み合わせ及びその使用 |
| ES2621377T3 (es) * | 2012-11-05 | 2017-07-03 | Morphosys Ag | Anticuerpo marcado radiactivamente y usos del mismo |
| US10342869B2 (en) * | 2012-12-07 | 2019-07-09 | The Regents Of The University Of California | Compositions comprising anti-CD38 antibodies and lenalidomide |
| UA118255C2 (uk) * | 2012-12-07 | 2018-12-26 | Санофі | Композиція, яка містить антитіло до cd38 і леналідомід |
| JP6279065B2 (ja) | 2013-03-13 | 2018-02-14 | サノフイ | 抗ｃｄ３８抗体およびカーフィルゾミブを含む組成物 |
| US11117975B2 (en) | 2013-04-29 | 2021-09-14 | Teva Pharmaceuticals Australia Pty Ltd | Anti-CD38 antibodies and fusions to attenuated interferon alpha-2B |
| ES2774976T3 (es) | 2013-04-29 | 2020-07-23 | Teva Pharmaceuticals Australia Pty Ltd | Anticuerpos anti-CD38 y fusiones con interferón alfa-2b atenuado |
| JP2017506640A (ja) * | 2014-02-14 | 2017-03-09 | セントローズ， エルエルシー | 細胞外標的化薬物共役体 |
| US9603927B2 (en) | 2014-02-28 | 2017-03-28 | Janssen Biotech, Inc. | Combination therapies with anti-CD38 antibodies |
| US9732154B2 (en) | 2014-02-28 | 2017-08-15 | Janssen Biotech, Inc. | Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia |
| UA119352C2 (uk) * | 2014-05-01 | 2019-06-10 | Тева Фармасьютикалз Острейліа Пті Лтд | Комбінація леналідоміду або помалідоміду і конструкції анти-cd38 антитіло-атенуйований інтерферон альфа-2b та спосіб лікування суб'єкта, який має cd38-експресуючу пухлину |
| EP3154581B1 (en) | 2014-06-16 | 2019-02-20 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Blocking cd38 using anti-cd38 f(ab')2 to protect nk cells |
| MX386886B (es) | 2014-09-09 | 2025-03-12 | Janssen Biotech Inc | Combinación de anticuerpos anti-cd38 y ácido todo-trans retinoico para usarse en terapias. |
| CA2965414C (en) | 2014-10-29 | 2024-01-09 | Teva Pharmaceuticals Australia Pty Ltd | Interferon .alpha.2.beta. variants |
| AU2015358615B2 (en) | 2014-12-04 | 2021-08-05 | Janssen Biotech, Inc. | Anti-CD38 antibodies for treatment of acute myeloid leukemia |
| MA41555A (fr) * | 2015-02-17 | 2017-12-26 | Millennium Pharm Inc | Polythérapie pour le traitement du cancer |
| ES2927119T3 (es) * | 2015-04-08 | 2022-11-02 | Sorrento Therapeutics Inc | Productos terapéuticos de anticuerpos que se unen a CD38 |
| PT3294769T (pt) | 2015-05-13 | 2021-04-13 | Morphosys Ag | Tratamento para mieloma múltiplo (mm) |
| MX389805B (es) | 2015-05-20 | 2025-03-11 | Janssen Biotech Inc | Anticuerpos anti-cd38 para el tratamiento de amiloidosis de cadena ligera y otras enfermedades malignas hematológicas positivas para cd38. |
| AU2016282674B2 (en) | 2015-06-22 | 2022-01-13 | Janssen Biotech, Inc. | Combination therapies for heme malignancies with anti-CD38 antibodies and survivin inhibitors |
| US20170044265A1 (en) | 2015-06-24 | 2017-02-16 | Janssen Biotech, Inc. | Immune Modulation and Treatment of Solid Tumors with Antibodies that Specifically Bind CD38 |
| NZ777930A (en) | 2015-07-16 | 2025-05-02 | Inhibrx Biosciences Inc | Multivalent and multispecific dr5-binding fusion proteins |
| CN105079776B (zh) * | 2015-09-17 | 2018-09-21 | 中南大学 | 一种石蒜碱和硼替佐米组合物的药物用途 |
| US10781261B2 (en) | 2015-11-03 | 2020-09-22 | Janssen Biotech, Inc. | Subcutaneous formulations of anti-CD38 antibodies and their uses |
| DK3827845T3 (da) | 2015-11-03 | 2022-05-23 | Janssen Biotech Inc | Subkutane formuleringer af anti-cd38-antistoffer og anvendelser deraf |
| WO2017149122A1 (en) * | 2016-03-04 | 2017-09-08 | Morphosys Ag | Clinical assessment of m-protein response in multiple myeloma |
| JP2019527678A (ja) | 2016-06-28 | 2019-10-03 | ユーエムセー・ユトレヒト・ホールディング・ベー・フェー | ＣＤ３８に特異的に結合する抗体によるＩｇＥ媒介疾患の治療 |
| MA45674A (fr) | 2016-07-15 | 2019-05-22 | Takeda Pharmaceuticals Co | Méthodes et matériaux permettant d'évaluer une réponse à des traitements de déplétion de plasmoblastes et de plasmocytes |
| EP4295918A3 (en) | 2016-11-02 | 2024-03-20 | Bristol-Myers Squibb Company | Bispecific antibody against bcma and cd3 and an immunological drug for combined use in treating multiple myeloma |
| EP3661557B1 (en) | 2017-07-31 | 2025-09-03 | Actinium Pharmaceuticals, Inc. | Treatments for a hematological malignancy |
| WO2019035938A1 (en) | 2017-08-16 | 2019-02-21 | Elstar Therapeutics, Inc. | MULTISPECIFIC MOLECULES BINDING TO BCMA AND USES THEREOF |
| JP2021502961A (ja) | 2017-10-31 | 2021-02-04 | ヤンセン バイオテツク，インコーポレーテツド | 高リスク多発性骨髄腫の治療方法 |
| KR20210006321A (ko) | 2018-01-12 | 2021-01-18 | 다케다 야쿠힌 고교 가부시키가이샤 | 항-cd38 항체의 피하 투여 |
| WO2020046767A1 (en) * | 2018-08-26 | 2020-03-05 | Trovagene, Inc. | Plk1 target phosphorylation status and treatment of cancer with plk1 inhibitors |
| EP3938394A1 (en) * | 2019-03-15 | 2022-01-19 | MorphoSys AG | Anti-cd38 antibodies and pharmaceutical compositions thereof for the treatment of autoantibody-mediated autoimmune disease |
| CN113993543B (zh) | 2019-06-10 | 2024-07-12 | 武田药品工业株式会社 | 使用抗cd38抗体的组合疗法 |
| US20240003879A1 (en) | 2020-11-27 | 2024-01-04 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for diagnosis and monitoring of toxic epidermal necrolysis |
| WO2022232557A1 (en) * | 2021-04-30 | 2022-11-03 | Adagio Therapeutics, Inc. | Compounds specific to coronavirus s protein and uses thereof |
| WO2023059900A2 (en) * | 2021-10-08 | 2023-04-13 | Invivyd, Inc. | Pharmaceutical formulations comprising anti-coronavirus s protein antibodies and uses thereof |
| TW202430548A (zh) * | 2022-09-29 | 2024-08-01 | 日商武田藥品工業股份有限公司 | Ｃｄ３８結合融合蛋白組合療法 |
| WO2025042742A1 (en) | 2023-08-18 | 2025-02-27 | Bristol-Myers Squibb Company | Compositions comprising antibodies that bind bcma and cd3 and methods of treatment |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020164788A1 (en) | 1994-12-02 | 2002-11-07 | The Wellcome Foundation Limited | Humanized antibodies to CD38 |
| WO1999062526A2 (en) | 1998-06-05 | 1999-12-09 | Mayo Foundation For Medical Education And Research | Use of genetically engineered antibodies to cd38 to treat multiple myeloma |
| US7223397B1 (en) | 1999-01-07 | 2007-05-29 | Research Development Foundation | Potentiation of anti-CD38-Immunotoxin cytotoxicity |
| HU230769B1 (hu) | 1999-01-15 | 2018-03-28 | Genentech Inc. | Módosított effektor-funkciójú polipeptid-változatok |
| DE19933130A1 (de) | 1999-07-19 | 2001-01-25 | Giesecke & Devrient Gmbh | Operandenstapelspeicher und Verfahren zum Betreiben eines Operandenstapelspeichers |
| EP1174440A1 (en) | 2000-07-19 | 2002-01-23 | U-BISys B.V. | A selectively-expressed epitope on the human CD38 molecule detected by a phage display library-derived human scFv antibody fragment |
| AU2002306596B2 (en) | 2001-02-27 | 2008-01-17 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Analogs of thalidomide as potential angiogenesis inhibitors |
| WO2004029207A2 (en) | 2002-09-27 | 2004-04-08 | Xencor Inc. | Optimized fc variants and methods for their generation |
| JP2006524039A (ja) | 2003-01-09 | 2006-10-26 | マクロジェニクス，インコーポレーテッド | 変異型Ｆｃ領域を含む抗体の同定および作製ならびにその利用法 |
| WO2005016326A2 (en) | 2003-07-11 | 2005-02-24 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Analogs of thalidomide as potential angiogenesis inhibitors |
| DK2511297T3 (en) | 2004-02-06 | 2015-06-15 | Morphosys Ag | Human anti-CD38 antibodies and their applications |
| US8263746B2 (en) | 2004-02-06 | 2012-09-11 | Morphosys Ag | Anti-CD38 human antibodies and uses thereof |
| EP2567976B1 (en) | 2005-03-23 | 2017-07-19 | Genmab A/S | Antibodies against CD38 for treatment of multiple myeloma |
| TW200745162A (en) | 2005-05-24 | 2007-12-16 | Morphosys Ag | Generation and profiling of fully human hucal gold-derived therapeutic antibodies specific for human CD38 |
| EP2860192B1 (en) | 2005-10-12 | 2017-09-27 | MorphoSys AG | Generation and profiling of fully human HuCAL GOLD-derived therapeutic antibodies specific for human CD38 |
| EP3569245A1 (en) * | 2006-09-26 | 2019-11-20 | Genmab A/S | Combination treatment of cd38-expressing tumors |
| ATE462248T1 (de) | 2006-09-28 | 2010-04-15 | Nokia Siemens Networks Gmbh | Steuerung der überlastdetektion in hsdpa systemen |
| EP1914242A1 (en) | 2006-10-19 | 2008-04-23 | Sanofi-Aventis | Novel anti-CD38 antibodies for the treatment of cancer |
| WO2010008726A1 (en) * | 2008-06-16 | 2010-01-21 | Immunogen Inc. | Novel synergistic effects |
| GB2461546B (en) | 2008-07-02 | 2010-07-07 | Argen X Bv | Antigen binding polypeptides |
| EP2191842A1 (en) * | 2008-11-28 | 2010-06-02 | Sanofi-Aventis | Antitumor combinations containing antibodies recognizing specifically CD38 and cytarabine |
| EP2191840A1 (en) | 2008-11-28 | 2010-06-02 | Sanofi-Aventis | Antitumor combinations containing antibodies recognizing specifically CD38 and melphalan |
| EP2191841A1 (en) * | 2008-11-28 | 2010-06-02 | Sanofi-Aventis | Antitumor combinations containing antibodies recognizing specifically CD38 and vincristine |
| EP2191843A1 (en) * | 2008-11-28 | 2010-06-02 | Sanofi-Aventis | Antitumor combinations containing antibodies recognizing specifically CD38 and cyclophosphamide |
| SI2621531T1 (sl) | 2010-09-27 | 2017-06-30 | Morphosys Ag | Anti-cd38 protitelo in lenalidomid ali bortezomib za zdravljenje multiplega mieloma in nhl |
| UA112170C2 (uk) | 2010-12-10 | 2016-08-10 | Санофі | Протипухлинна комбінація, що містить антитіло, яке специфічно розпізнає cd38, і бортезоміб |
| JOP20210044A1 (ar) | 2010-12-30 | 2017-06-16 | Takeda Pharmaceuticals Co | الأجسام المضادة لـ cd38 |
-
2011
- 2011-09-26 SI SI201131109A patent/SI2621531T1/sl unknown
- 2011-09-26 AU AU2011310696A patent/AU2011310696B2/en active Active
- 2011-09-26 KR KR1020137010537A patent/KR101912957B1/ko active Active
- 2011-09-26 RU RU2013113933/15A patent/RU2595839C2/ru active
- 2011-09-26 LT LTEP11761360.4T patent/LT2621531T/lt unknown
- 2011-09-26 DK DK11761360.4T patent/DK2621531T3/en active
- 2011-09-26 PL PL11761360T patent/PL2621531T3/pl unknown
- 2011-09-26 JP JP2013529669A patent/JP6087283B2/ja not_active Expired - Fee Related
- 2011-09-26 HU HUE11761360A patent/HUE031956T2/en unknown
- 2011-09-26 NZ NZ607473A patent/NZ607473A/en unknown
- 2011-09-26 CN CN201180043775.1A patent/CN103118706B/zh active Active
- 2011-09-26 EP EP11761360.4A patent/EP2621531B8/en active Active
- 2011-09-26 WO PCT/EP2011/066648 patent/WO2012041800A1/en not_active Ceased
- 2011-09-26 ES ES11761360.4T patent/ES2617446T3/es active Active
- 2011-09-26 US US13/825,325 patent/US8877899B2/en active Active
- 2011-09-26 BR BR112013006769-1A patent/BR112013006769B1/pt active IP Right Grant
- 2011-09-26 SG SG2013015235A patent/SG188345A1/en unknown
- 2011-09-26 CA CA2812631A patent/CA2812631C/en active Active
- 2011-09-26 MX MX2013003304A patent/MX350540B/es active IP Right Grant
- 2011-09-26 PT PT117613604T patent/PT2621531T/pt unknown
-
2013
- 2013-02-18 ZA ZA2013/01232A patent/ZA201301232B/en unknown
- 2013-02-26 IL IL224915A patent/IL224915A/en active IP Right Grant
-
2014
- 2014-09-29 US US14/500,366 patent/US9289490B2/en active Active
-
2016
- 2016-02-05 US US15/016,330 patent/US9765152B2/en active Active
- 2016-10-21 JP JP2016206756A patent/JP6231642B2/ja active Active
-
2017
- 2017-08-07 US US15/670,811 patent/US10308722B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2017048208A5 (https=) | ||
| JP2015530399A5 (https=) | ||
| NZ607473A (en) | Anti-cd38 antibody and lenalidomide or bortezomib for the treatment of multiple myeloma and nhl | |
| JP2013542191A5 (https=) | ||
| JP2016034978A5 (https=) | ||
| UA118255C2 (uk) | Композиція, яка містить антитіло до cd38 і леналідомід | |
| JP2012136541A5 (https=) | ||
| JP2016518387A5 (https=) | ||
| NZ606095A (en) | Anti-n3pglu amyloid beta peptide antibodies and uses thereof | |
| JP2011251975A5 (https=) | ||
| MX2014001374A (es) | Composicion farmaceutica para el tratamiento y/o prevencion de cancer. | |
| JP2019506403A5 (https=) | ||
| NZ707377A (en) | Combination therapy methods for treating proliferative diseases | |
| JP2015529225A5 (https=) | ||
| JP2018506550A5 (https=) | ||
| HRP20171964T1 (hr) | Kombinacije i njihova upotreba | |
| JP2015526440A5 (https=) | ||
| EA201690905A1 (ru) | Специфические антитела против cd38 для лечения злокачественных новообразований у человека | |
| JP2017515815A5 (https=) | ||
| RU2017134443A (ru) | Способ лечения с применением традипитанта | |
| RU2017116740A (ru) | Комбинации для лечения рассеянного склероза | |
| JP2019533682A5 (https=) | ||
| HRP20210838T1 (hr) | Kombinacija protutijela anti-cd19 s inhibitorom bcl-2 te njihove uporabe | |
| JP2023093495A5 (https=) | ||
| JP2016514148A5 (https=) |