AU5981796A - Pyrularia thionin containing immunotoxins and immunotoxin-li ke conjugates - Google Patents

Pyrularia thionin containing immunotoxins and immunotoxin-li ke conjugates

Info

Publication number
AU5981796A
AU5981796A AU59817/96A AU5981796A AU5981796A AU 5981796 A AU5981796 A AU 5981796A AU 59817/96 A AU59817/96 A AU 59817/96A AU 5981796 A AU5981796 A AU 5981796A AU 5981796 A AU5981796 A AU 5981796A
Authority
AU
Australia
Prior art keywords
immunotoxin
conjugates
containing immunotoxins
pyrularia
thionin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU59817/96A
Inventor
Sardar E. Gasanov
Eppie D. Rael
Leo P. Vernon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
THERA PRO
Original Assignee
THERA PRO
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by THERA PRO filed Critical THERA PRO
Publication of AU5981796A publication Critical patent/AU5981796A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • A61K47/6817—Toxins
    • A61K47/6819—Plant toxins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Botany (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU59817/96A 1995-06-07 1996-06-05 Pyrularia thionin containing immunotoxins and immunotoxin-li ke conjugates Abandoned AU5981796A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47979995A 1995-06-07 1995-06-07
US479799 1995-06-07
PCT/US1996/008811 WO1996041608A2 (en) 1995-06-07 1996-06-05 Pyrularia thionin containing immunotoxins and immunotoxin-like conjugates

Publications (1)

Publication Number Publication Date
AU5981796A true AU5981796A (en) 1997-01-09

Family

ID=23905495

Family Applications (1)

Application Number Title Priority Date Filing Date
AU59817/96A Abandoned AU5981796A (en) 1995-06-07 1996-06-05 Pyrularia thionin containing immunotoxins and immunotoxin-li ke conjugates

Country Status (2)

Country Link
AU (1) AU5981796A (en)
WO (1) WO1996041608A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9926875D0 (en) 1999-11-12 2000-01-12 Microbiological Research Agenc Use of lytic toxins and toxin conjugates
AU2000275771B2 (en) * 2000-09-11 2006-06-29 Therapro Technologies, Inc. Thionin as an antineoplastic and immunostimulant
CA3107383A1 (en) * 2018-07-23 2020-01-30 Magenta Therapeutics, Inc. Use of anti-cd5 antibody drug conjugate (adc) in allogeneic cell therapy
US20200407440A1 (en) 2019-04-24 2020-12-31 Magenta Therapeutics, Inc. Amatoxin antibody-drug conjugates and uses thereof

Also Published As

Publication number Publication date
WO1996041608A2 (en) 1996-12-27
WO1996041608A3 (en) 1997-02-06

Similar Documents

Publication Publication Date Title
GB2297443B (en) Amplifier
AU7718898A (en) Txu-7-pap immunotoxin and use thereof
AU6029594A (en) Factor viii - polymeric conjugates
AU6206096A (en) Tie
AU7417896A (en) Neuroprotective agents
EP0744753A3 (en) Sense amplifiers
AU4245996A (en) Improved class ab amplifier
GB9516025D0 (en) Amplifier
AU4344696A (en) Oligonucleotide-dendrimer conjugates
GB2308697B (en) Sense amplifier
GB9501624D0 (en) Amplifier
AU4268496A (en) Targeting complexes and use thereof
GB9502894D0 (en) Amplifiers
AU7544396A (en) Triazole derivatives and uses thereof
AU5981796A (en) Pyrularia thionin containing immunotoxins and immunotoxin-li ke conjugates
AU5188296A (en) Carbopeptoids and carbonucleotoids
AU2897500A (en) "rzao" steering and variants
AU1341497A (en) Pyrrolidine derivatives
AU5009993A (en) Isoprostane-protein conjugates
AU5748994A (en) Potent and specific chemically-conjugated immunotoxins
GB9519233D0 (en) Amplifier arrangements
GB9618138D0 (en) Amplifier arrangements
AU4677196A (en) Phenylamidinothiophene derivatives and antiphlogistic agent containing the same
GB9623158D0 (en) Amplifiers and compound transistors
AU2887195A (en) Kit for pretargeting and novel pretargeting conjugates