JP2021502070A5 - - Google Patents

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Publication number

JP2021502070A5

JP2021502070A5 JP2020524450A JP2020524450A JP2021502070A5 JP 2021502070 A5 JP2021502070 A5 JP 2021502070A5 JP 2020524450 A JP2020524450 A JP 2020524450A JP 2020524450 A JP2020524450 A JP 2020524450A JP 2021502070 A5 JP2021502070 A5 JP 2021502070A5

Authority

JP

Japan

Prior art keywords

domain

vector

cancer

car

use according

Prior art date

2018-11-02

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
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• 108010019670 Chimeric Antigen Receptors Proteins 0.000 claims 10
• 210000001744 T-lymphocyte Anatomy 0.000 claims 9
• 239000000427 antigen Substances 0.000 claims 9
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• 101001103039 Homo sapiens Inactive tyrosine-protein kinase transmembrane receptor ROR1 Proteins 0.000 claims 5
• 101001103036 Homo sapiens Nuclear receptor ROR-alpha Proteins 0.000 claims 5
• 102100039615 Inactive tyrosine-protein kinase transmembrane receptor ROR1 Human genes 0.000 claims 5
• 239000002773 nucleotide Substances 0.000 claims 5
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• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
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