JP2021118906A5 - - Google Patents
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- Publication number
- JP2021118906A5 JP2021118906A5 JP2021077751A JP2021077751A JP2021118906A5 JP 2021118906 A5 JP2021118906 A5 JP 2021118906A5 JP 2021077751 A JP2021077751 A JP 2021077751A JP 2021077751 A JP2021077751 A JP 2021077751A JP 2021118906 A5 JP2021118906 A5 JP 2021118906A5
- Authority
- JP
- Japan
- Prior art keywords
- hap
- cap
- hydroxyapatite
- calcium phosphate
- biphasic calcium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000316 bone substitute Substances 0.000 claims 11
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims 11
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims 11
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims 10
- 230000002051 biphasic effect Effects 0.000 claims 9
- 229910000389 calcium phosphate Inorganic materials 0.000 claims 9
- 239000001506 calcium phosphate Substances 0.000 claims 9
- 235000011010 calcium phosphates Nutrition 0.000 claims 9
- 239000000463 material Substances 0.000 claims 9
- 239000011162 core material Substances 0.000 claims 8
- 238000000034 method Methods 0.000 claims 7
- 238000004630 atomic force microscopy Methods 0.000 claims 6
- 239000002159 nanocrystal Substances 0.000 claims 6
- 239000008187 granular material Substances 0.000 claims 4
- 238000006243 chemical reaction Methods 0.000 claims 3
- DNIAPMSPPWPWGF-GSVOUGTGSA-N (R)-(-)-Propylene glycol Chemical compound C[C@@H](O)CO DNIAPMSPPWPWGF-GSVOUGTGSA-N 0.000 claims 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- 210000000988 bone and bone Anatomy 0.000 claims 2
- 150000002191 fatty alcohols Chemical class 0.000 claims 2
- 229910052500 inorganic mineral Inorganic materials 0.000 claims 2
- 239000011707 mineral Substances 0.000 claims 2
- 239000007864 aqueous solution Substances 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 239000000872 buffer Substances 0.000 claims 1
- 239000007853 buffer solution Substances 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 claims 1
- 229910052753 mercury Inorganic materials 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 239000008055 phosphate buffer solution Substances 0.000 claims 1
- 238000002459 porosimetry Methods 0.000 claims 1
- 239000011148 porous material Substances 0.000 claims 1
- 239000011343 solid material Substances 0.000 claims 1
- 230000001954 sterilising effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17207235 | 2017-12-14 | ||
| EP17207235.7 | 2017-12-14 | ||
| JP2020532744A JP6880330B2 (ja) | 2017-12-14 | 2018-12-13 | 骨代替材料 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020532744A Division JP6880330B2 (ja) | 2017-12-14 | 2018-12-13 | 骨代替材料 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021118906A JP2021118906A (ja) | 2021-08-12 |
| JP2021118906A5 true JP2021118906A5 (enExample) | 2021-12-02 |
| JP7249376B2 JP7249376B2 (ja) | 2023-03-30 |
Family
ID=60781527
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020532744A Active JP6880330B2 (ja) | 2017-12-14 | 2018-12-13 | 骨代替材料 |
| JP2021077751A Active JP7249376B2 (ja) | 2017-12-14 | 2021-04-30 | 骨代替材料 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020532744A Active JP6880330B2 (ja) | 2017-12-14 | 2018-12-13 | 骨代替材料 |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US11351287B2 (enExample) |
| EP (1) | EP3544643B1 (enExample) |
| JP (2) | JP6880330B2 (enExample) |
| KR (1) | KR102233325B1 (enExample) |
| CN (1) | CN111465418B (enExample) |
| AU (1) | AU2018382557B2 (enExample) |
| BR (1) | BR112020010213B1 (enExample) |
| CA (1) | CA3083852A1 (enExample) |
| DK (1) | DK3544643T3 (enExample) |
| ES (1) | ES2803976T3 (enExample) |
| HU (1) | HUE050062T2 (enExample) |
| IL (1) | IL275203B2 (enExample) |
| MX (1) | MX2020005846A (enExample) |
| PL (1) | PL3544643T3 (enExample) |
| PT (1) | PT3544643T (enExample) |
| SG (1) | SG11202004726YA (enExample) |
| TW (1) | TWI852918B (enExample) |
| WO (1) | WO2019115704A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT3544643T (pt) | 2017-12-14 | 2020-07-27 | Geistlich Pharma Ag | Material de substituição óssea |
| KR102636183B1 (ko) | 2019-06-14 | 2024-02-13 | 가이스틀리히 파마 아게 | 골 대체 물질의 콜라겐 기질 또는 그래뉼레이트 블렌드 |
| DE202021004032U1 (de) | 2020-08-29 | 2022-10-10 | BioScientific Designs d.o.o | Ein steriles Medizinprodukt als Knochenersatz, Zubereitung und Verwendung |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60220056A (ja) * | 1984-04-18 | 1985-11-02 | 三菱マテリアル株式会社 | 人工歯 |
| US4865602A (en) | 1986-11-06 | 1989-09-12 | Collagen Corporation | Gamma irradiation of collagen/mineral mixtures |
| DE3711426A1 (de) | 1987-04-04 | 1988-10-13 | Mtu Muenchen Gmbh | Implantat mit bioaktivem ueberzug |
| GB8813033D0 (en) | 1988-06-02 | 1988-07-06 | Geistlich Soehne Ag | Chemical compound |
| ES2167330T3 (es) | 1992-02-28 | 2002-05-16 | Cohesion Tech Inc | Composiciones ceramicas inyectables y su procedimiento de preparacion y de utilizacion. |
| US5763092A (en) | 1993-09-15 | 1998-06-09 | Etex Corporation | Hydroxyapatite coatings and a method of their manufacture |
| IT1288038B1 (it) | 1996-04-30 | 1998-09-10 | Flametal S P A | Procedimento per la preparazione di rivestimenti di idrossiapatite |
| US6338752B1 (en) | 2000-04-20 | 2002-01-15 | Purzer Pharmaceutical Co., Ltd. | α-TCP/HAP biphasic cement and its preparing process |
| US20030026770A1 (en) | 2001-07-25 | 2003-02-06 | Szymaitis Dennis W. | Periodontal regeneration composition and method of using same |
| US20070026030A1 (en) | 2005-07-27 | 2007-02-01 | Berkeley Advanced Biomaterials, Inc. | Method of preparing rheological materials for bone and cartilage repair |
| WO2008051555A2 (en) * | 2006-10-24 | 2008-05-02 | Biomet 3I, Llc. | Deposition of discrete nanoparticles on a nanostructured surface of an implant |
| CN1974876B (zh) * | 2006-11-02 | 2010-07-07 | 华南理工大学 | 钛金属表面生物活性膜层及其喷砂-微弧氧化复合工艺 |
| ES2402961T3 (es) | 2009-06-23 | 2013-05-10 | Geistlich Pharma Ag | Material sustitutivo del hueso |
| US20130045360A1 (en) | 2010-01-29 | 2013-02-21 | Georgia Tech Research Corporation | Surface modification of implant devices |
| CN101850131A (zh) * | 2010-04-30 | 2010-10-06 | 武汉理工大学 | 晶核引导骨性结合的金属植入体表面改性的方法 |
| US9107983B2 (en) | 2010-10-27 | 2015-08-18 | Warsaw Orthopedic, Inc. | Osteoconductive matrices comprising statins |
| EP2654816B1 (en) | 2010-12-22 | 2015-02-11 | Geistlich Pharma AG | Bone substitute material |
| DE102011050183A1 (de) * | 2011-05-06 | 2012-11-08 | Aesculap Ag | Oberflächenprofilierter Gitterkörper |
| GB201122405D0 (en) | 2011-12-23 | 2012-02-08 | Univ Aberdeen | Calcium phosphate material |
| WO2014183770A1 (en) | 2013-05-15 | 2014-11-20 | Euroresearch S.R.L. | "collagen powder, composition and use" |
| NL2011195C2 (en) | 2013-07-18 | 2015-01-21 | Xpand Biotechnology B V | Method for producing an osteoinductive calcium phosphate and products thus obtained. |
| EP2826495A1 (en) | 2013-07-19 | 2015-01-21 | Geistlich Pharma AG | Biomimetic collagen-hydroxyapatite composite material |
| TWI783093B (zh) | 2017-12-14 | 2022-11-11 | 瑞士商蓋茲特利製藥公司 | 骨替代材料及其製備及應用 |
| CN111511415B (zh) | 2017-12-14 | 2021-04-20 | 盖斯特里希医药公司 | 干式植入物组合物和可注射的水性植入物制剂 |
| PT3544643T (pt) | 2017-12-14 | 2020-07-27 | Geistlich Pharma Ag | Material de substituição óssea |
-
2018
- 2018-12-13 PT PT188160634T patent/PT3544643T/pt unknown
- 2018-12-13 KR KR1020207016840A patent/KR102233325B1/ko active Active
- 2018-12-13 JP JP2020532744A patent/JP6880330B2/ja active Active
- 2018-12-13 SG SG11202004726YA patent/SG11202004726YA/en unknown
- 2018-12-13 TW TW107145009A patent/TWI852918B/zh active
- 2018-12-13 MX MX2020005846A patent/MX2020005846A/es unknown
- 2018-12-13 HU HUE18816063A patent/HUE050062T2/hu unknown
- 2018-12-13 BR BR112020010213-0A patent/BR112020010213B1/pt active IP Right Grant
- 2018-12-13 EP EP18816063.4A patent/EP3544643B1/en active Active
- 2018-12-13 ES ES18816063T patent/ES2803976T3/es active Active
- 2018-12-13 CN CN201880080248.XA patent/CN111465418B/zh active Active
- 2018-12-13 CA CA3083852A patent/CA3083852A1/en active Pending
- 2018-12-13 PL PL18816063T patent/PL3544643T3/pl unknown
- 2018-12-13 WO PCT/EP2018/084783 patent/WO2019115704A1/en not_active Ceased
- 2018-12-13 DK DK18816063.4T patent/DK3544643T3/da active
- 2018-12-13 AU AU2018382557A patent/AU2018382557B2/en active Active
- 2018-12-13 IL IL275203A patent/IL275203B2/en unknown
- 2018-12-14 US US16/220,331 patent/US11351287B2/en active Active
-
2019
- 2019-09-25 US US16/582,301 patent/US10646615B2/en active Active
-
2021
- 2021-04-30 JP JP2021077751A patent/JP7249376B2/ja active Active
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