JP2021036002A5 - - Google Patents
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- Publication number
- JP2021036002A5 JP2021036002A5 JP2020201994A JP2020201994A JP2021036002A5 JP 2021036002 A5 JP2021036002 A5 JP 2021036002A5 JP 2020201994 A JP2020201994 A JP 2020201994A JP 2020201994 A JP2020201994 A JP 2020201994A JP 2021036002 A5 JP2021036002 A5 JP 2021036002A5
- Authority
- JP
- Japan
- Prior art keywords
- sodium salt
- hydrate
- crystal
- crystals
- solvate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000013078 crystal Substances 0.000 claims 31
- -1 6SL sodium salt Chemical class 0.000 claims 29
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims 9
- 239000012453 solvate Substances 0.000 claims 8
- 238000004519 manufacturing process Methods 0.000 claims 6
- 239000007864 aqueous solution Substances 0.000 claims 5
- 230000001376 precipitating effect Effects 0.000 claims 4
- 239000002904 solvent Substances 0.000 claims 4
- 238000000634 powder X-ray diffraction Methods 0.000 claims 3
- 239000000243 solution Substances 0.000 claims 3
- TYALNJQZQRNQNQ-UHFFFAOYSA-N #alpha;2,6-sialyllactose Natural products O1C(C(O)C(O)CO)C(NC(=O)C)C(O)CC1(C(O)=O)OCC1C(O)C(O)C(O)C(OC2C(C(O)C(O)OC2CO)O)O1 TYALNJQZQRNQNQ-UHFFFAOYSA-N 0.000 claims 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 1
- TYALNJQZQRNQNQ-JLYOMPFMSA-N alpha-Neup5Ac-(2->6)-beta-D-Galp-(1->4)-beta-D-Glcp Chemical compound O1[C@@H]([C@H](O)[C@H](O)CO)[C@H](NC(=O)C)[C@@H](O)C[C@@]1(C(O)=O)OC[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O)[C@H](O)O[C@@H]2CO)O)O1 TYALNJQZQRNQNQ-JLYOMPFMSA-N 0.000 claims 1
- 150000008064 anhydrides Chemical class 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- 229910052708 sodium Inorganic materials 0.000 claims 1
- 239000011734 sodium Substances 0.000 claims 1
- 159000000000 sodium salts Chemical class 0.000 claims 1
- 238000003756 stirring Methods 0.000 claims 1
- 238000012916 structural analysis Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022038512A JP2022069548A (ja) | 2015-11-18 | 2022-03-11 | ６’－シアリルラクトースナトリウム塩の結晶およびその製造方法 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015225652 | 2015-11-18 | ||
| JP2015225652 | 2015-11-18 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017551949A Division JP7267675B2 (ja) | 2015-11-18 | 2016-11-18 | ６’－シアリルラクトースナトリウム塩の結晶およびその製造方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022038512A Division JP2022069548A (ja) | 2015-11-18 | 2022-03-11 | ６’－シアリルラクトースナトリウム塩の結晶およびその製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021036002A JP2021036002A (ja) | 2021-03-04 |
| JP2021036002A5 true JP2021036002A5 (https=) | 2021-04-22 |
Family
ID=58717459
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017551949A Active JP7267675B2 (ja) | 2015-11-18 | 2016-11-18 | ６’－シアリルラクトースナトリウム塩の結晶およびその製造方法 |
| JP2020201994A Withdrawn JP2021036002A (ja) | 2015-11-18 | 2020-12-04 | ６’−シアリルラクトースナトリウム塩の結晶およびその製造方法 |
| JP2022038512A Withdrawn JP2022069548A (ja) | 2015-11-18 | 2022-03-11 | ６’－シアリルラクトースナトリウム塩の結晶およびその製造方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017551949A Active JP7267675B2 (ja) | 2015-11-18 | 2016-11-18 | ６’－シアリルラクトースナトリウム塩の結晶およびその製造方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022038512A Withdrawn JP2022069548A (ja) | 2015-11-18 | 2022-03-11 | ６’－シアリルラクトースナトリウム塩の結晶およびその製造方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US10745432B2 (https=) |
| EP (1) | EP3378868A4 (https=) |
| JP (3) | JP7267675B2 (https=) |
| WO (1) | WO2017086443A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017195743A1 (ja) * | 2016-05-09 | 2017-11-16 | 協和発酵バイオ株式会社 | ３'－シアリルラクトースナトリウム塩・ｎ水和物の結晶及びその製造方法 |
| WO2018225790A1 (ja) * | 2017-06-08 | 2018-12-13 | 協和発酵バイオ株式会社 | 酸化型グルタチオン・二カチオン塩の結晶及びその製造方法 |
| US11214588B2 (en) | 2017-06-30 | 2022-01-04 | Glycom A/S | Synthesis of oligosaccharides |
| WO2019169188A1 (en) * | 2018-02-28 | 2019-09-06 | The Regents Of The University Of California | Methods and therapies for treating atherosclerosis and/or hyperlipidemia using oligosaccharides |
| EP4025072B1 (en) | 2019-09-04 | 2025-08-20 | Inbiose N.V. | Process for removing an antifoam agent from a solution comprising a human milk oligosaccharide and related compositions |
| CN115703772B (zh) * | 2021-08-09 | 2024-07-30 | 天地恒一制药股份有限公司 | 艾拉莫德共晶，及其制备方法与应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5575916A (en) | 1994-11-07 | 1996-11-19 | Neose Pharmaceuticals, Inc. | Method of processing a cheese processing waste stream |
| JP4082746B2 (ja) | 1995-03-20 | 2008-04-30 | 雪印乳業株式会社 | シアリルラクトースの分離方法 |
| IT1394503B1 (it) | 2009-04-06 | 2012-07-05 | Inalco Spa | Sali di 6'-sialillattosio e processo per la loro sintesi e per la sintesi di altri alfa-sialiloligosaccaridi. |
| CA2789821A1 (en) | 2010-02-19 | 2011-08-25 | Glycom A/S | Production of 6'-o-sialyllactose and intermediates |
-
2016
- 2016-11-18 JP JP2017551949A patent/JP7267675B2/ja active Active
- 2016-11-18 EP EP16866443.1A patent/EP3378868A4/en active Pending
- 2016-11-18 US US15/769,025 patent/US10745432B2/en active Active
- 2016-11-18 WO PCT/JP2016/084282 patent/WO2017086443A1/ja not_active Ceased
-
2020
- 2020-12-04 JP JP2020201994A patent/JP2021036002A/ja not_active Withdrawn
-
2022
- 2022-03-11 JP JP2022038512A patent/JP2022069548A/ja not_active Withdrawn
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