|
US922078A
(en)
|
1909-03-01 |
1909-05-18 |
Charles Burwell Benson |
Tongue-depressor.
|
|
DK166650B1
(da)
|
1991-03-15 |
1993-06-28 |
Aarhus Oliefabrik As |
Fedtbaser samt anvendelse af disse i kosmetiske og farmaceutiske emulsionsprodukter
|
|
US5977174A
(en)
|
1997-11-26 |
1999-11-02 |
Neuromedica, Inc. |
Cholinergic compositions and uses thereof
|
|
US5985936A
(en)
|
1997-12-18 |
1999-11-16 |
Forbes Medi-Tech, Inc. |
Method of preventing and delaying onset of Alzheimer's disease and composition therefor
|
|
NZ507791A
(en)
|
1998-05-19 |
2003-12-19 |
Res Dev Foundation |
Triterpene compositions from Acacia victoriae and methods for use thereof
|
|
DE60039232D1
(de)
|
1999-04-27 |
2008-07-31 |
Forbes Medi Tech Inc |
Verfahren zur Herstellung einer Phytosterolzusammensetzung
|
|
CN1129613C
(zh)
|
1999-12-24 |
2003-12-03 |
中国科学院上海药物研究所 |
夹竹桃花多糖及其制备方法和应用
|
|
US6629835B2
(en)
*
|
2000-08-01 |
2003-10-07 |
Metaproteomics, Llc |
Combinations of diterpene triepoxide lactones and ditepene lactones or triterpenes for synergistic inhibition of cyclooxygenase-2
|
|
US20020077350A1
(en)
|
2000-08-01 |
2002-06-20 |
Ashni Naturaceuticals, Inc. |
Compositions exhibiting synergistic inhibition of the expression and/or activity of clyclooxygenase-2
|
|
EP1309605A1
(en)
|
2000-08-18 |
2003-05-14 |
The Board Of Trustees Of The University Of Illinois |
Prodrugs of betulinic acid derivatives for the treatment of cancer and hiv
|
|
DE60204078T2
(de)
|
2001-04-09 |
2006-01-26 |
Loders Croklaan B.V. |
Konzentrat von Triterpenen
|
|
CA2446748C
(en)
|
2001-05-11 |
2011-03-08 |
University Of Ottawa |
Anxiolytic marcgraviaceae compositions containing betulinic acid, betulinic acid derivatives, and methods
|
|
EP1513403B1
(en)
|
2002-05-28 |
2017-02-15 |
Bette Pollard |
Cardiac glycosides to treat cystic fibrosis and other il-8 dependent disorders
|
|
US20070249711A1
(en)
|
2003-10-10 |
2007-10-25 |
Wonrack Choi |
Triterpene Compounds which are Effective on Improvement of Brain Function
|
|
ATE400262T1
(de)
*
|
2003-12-19 |
2008-07-15 |
Lipid Nutrition Bv |
Verwendung von zusammensetzungen mit oleansäure und ursolsäure zur herstellung eines medikaments zur behandlung von überempfindlichkeit und hyperreaktivität
|
|
AU2005224260A1
(en)
|
2004-03-17 |
2005-09-29 |
Panacos Pharmaceuticals, Inc. |
Pharmaceuticals salts of 3-O-(3',3'-dimethylsuccinyl) betulinic acid
|
|
US7118508B2
(en)
|
2004-07-28 |
2006-10-10 |
General Motors Corporation |
Planetary transmissions having three interconnected gear members and clutched input members
|
|
WO2006044916A2
(en)
|
2004-10-18 |
2006-04-27 |
Bionaut Pharmaceuticals, Inc. |
Use of na+/ k+-atpase inhibitors and antagonists thereof
|
|
CA2597300C
(en)
|
2005-02-09 |
2012-11-27 |
Rama Mukherjee |
Novel betulinic acid derivatives
|
|
WO2006105354A1
(en)
|
2005-03-29 |
2006-10-05 |
Regents Of The University Of Minnesota |
Selective oxidation of triterpenes employing tempo
|
|
US20060252733A1
(en)
|
2005-04-07 |
2006-11-09 |
Novelix Pharmaceuticals, Inc. |
Betulin, betulin derivatives, betulinic acid and betulinic acid derivatives as novel therapeutics in the treatment of disease of lipid and/or glucose metabolism
|
|
US20090131714A1
(en)
|
2005-06-08 |
2009-05-21 |
Krasutsky Pavel A |
Synthesis of betulonic and betulinic aldehydes
|
|
CA2611435C
(en)
|
2005-06-10 |
2013-01-08 |
Pola Chemical Industries Inc. |
Novel triterpenic acid derivative and preparation for external application for skin comprising the same
|
|
US7402325B2
(en)
|
2005-07-28 |
2008-07-22 |
Phoenix Biotechnology, Inc. |
Supercritical carbon dioxide extract of pharmacologically active components from Nerium oleander
|
|
CN101374527A
(zh)
|
2005-12-16 |
2009-02-25 |
帕纳克斯医药公司 |
3-o-(3’,3’-二甲基琥珀酰基)桦木酸的药物盐的制备方法
|
|
EP1803461A1
(en)
|
2005-12-27 |
2007-07-04 |
Heinz-Herbert Fiebig |
Therapeutic use of an extract from the leaves of Nerium oleander
|
|
GB0604535D0
(en)
|
2006-03-07 |
2006-04-12 |
Sndv Sprl |
Betulonic acid derivatives
|
|
DE102006020582A1
(de)
*
|
2006-05-03 |
2007-11-15 |
Gesellschaft zur Förderung der Krebstherapie e.V. |
Verfahren zur Herstellung einer triterpensäurehaltigen wässrigen Lösung, triterpensäurehaltige wässrige Lösung und deren Verwendung
|
|
US20090203661A1
(en)
|
2006-10-12 |
2009-08-13 |
Safe Stephen H |
Betulinic acid, derivatives and analogs thereof and uses therefor
|
|
AR063546A1
(es)
|
2006-11-03 |
2009-01-28 |
Panacos Pharmaceuticals Inc |
DERIVADOS DE TRITERPENO, METODOS PARA SU PREPARACION, COMPOSICIONES FARMACEUTICAS QUE LOS COMPRENDEN Y SU USO EN LA FABRICACION DE MEDICAMENTOS PARA EL TRATAMIENTO DE INFECCIoN POR EL VIRUS VIH.
|
|
WO2008091532A1
(en)
|
2007-01-19 |
2008-07-31 |
Panacos Pharmaceuticals, Inc. |
Salts of 3-o-(3',3'-dimethylsuccinyl)betulinic acid and solid state forms thereof
|
|
US8987212B2
(en)
|
2007-08-07 |
2015-03-24 |
Muhammed Majeed |
Oleanoyl peptide composition and method of treating skin aging
|
|
BRPI0820564A2
(pt)
|
2007-11-13 |
2017-05-23 |
Phoenix Biotechnology Inc |
método para determinar a probabilidade de uma resposta terapêutica na quimioterapia do câncer com glicosídeo cardíaco
|
|
ES2326065B1
(es)
|
2008-03-28 |
2010-07-08 |
Consejo Superior De Investigaciones Cientificas (Csic) |
Utilizacion de un triterpeno pentaciclico para la preparacion de una composicion farmaceutica destinada al tratamiento de la esclerosis multiple.
|
|
WO2009129548A1
(en)
|
2008-04-18 |
2009-10-22 |
Reata Pharmaceuticals, Inc. |
Antioxidant inflammation modulators: c-17 homologated oleanolic acid derivatives
|
|
TW201004627A
(en)
|
2008-04-18 |
2010-02-01 |
Reata Pharmaceuticals Inc |
Antioxidant inflammation modulators: novel derivatives of oleanolic acid
|
|
EA022588B1
(ru)
|
2008-04-18 |
2016-01-29 |
Ритэ Фамэсутикл, Инк. |
Антиоксидантные модуляторы воспаления: производные олеанолевой кислоты с насыщением в с-кольце
|
|
DK2276493T3
(da)
|
2008-04-18 |
2019-01-02 |
Reata Pharmaceuticals Inc |
Antioxidative inflammationsmodulatorer: oleanolsyrederivater med amino- og andre modifikationer ved c-17
|
|
WO2010028487A1
(en)
|
2008-09-10 |
2010-03-18 |
Université Du Québec À Chicoutimi |
Bidesmosidic betulin and betulinic acid derivatives and uses thereof as antitumor agents
|
|
US8778990B2
(en)
|
2008-11-04 |
2014-07-15 |
Trustees Of Dartmouth College |
Betulinic acid derivatives and methods of use thereof
|
|
US8802727B2
(en)
|
2009-07-14 |
2014-08-12 |
Hetero Research Foundation, Hetero Drugs Limited |
Pharmaceutically acceptable salts of betulinic acid derivatives
|
|
TW201104501A
(en)
|
2009-07-24 |
2011-02-01 |
Asustek Comp Inc |
Device and method for inputting Chinese character
|
|
CN101704872B
(zh)
|
2009-11-23 |
2012-06-27 |
张南 |
23-羟基白桦酸衍生物、其制备方法及应用
|
|
WO2011064710A1
(en)
|
2009-11-30 |
2011-06-03 |
University Of Kwazulu-Natal |
In vitro anti-sickling activity of betulinic acid, oleanolic acid and their derivatives
|
|
BR112012017073A2
(pt)
|
2010-01-11 |
2015-09-01 |
Phoenix Biotechnology Inc |
Método de tratamento de condições neurológicas com glicosídeos cardíacos
|
|
US9011937B2
(en)
|
2010-11-22 |
2015-04-21 |
Phoenix Biotechnology, Inc. |
Method of treating neurological conditions with extract of Nerium species or Thevetia species
|
|
TWI386415B
(zh)
|
2010-02-02 |
2013-02-21 |
Univ Kaohsiung Medical |
熊果酸衍生物及其醫藥組合物
|
|
CN107412775B
(zh)
*
|
2010-11-22 |
2021-01-05 |
菲尼克斯生物技术公司 |
用夹竹桃属物种或黄花夹竹桃属物种的提取物治疗神经病症的方法
|
|
TWI410431B
(zh)
|
2010-12-22 |
2013-10-01 |
Ind Tech Res Inst |
齊敦果酸衍生物在製備預防或治療ｃ型肝炎之藥物的用途
|
|
US20140221328A1
(en)
|
2011-01-10 |
2014-08-07 |
Bandi Parthasaradhi Reddy |
Pharmaceutically acceptable salts of novel betulinic acid derivatives
|
|
SI2670764T1
(sl)
|
2011-01-31 |
2016-03-31 |
Bristol-Myers Squibb Company |
C-28 amini derivatov c-3 modificirane betulinske kisline inhibitorjev zorenja hiv
|
|
CN102558280B
(zh)
|
2011-11-18 |
2014-09-17 |
温州大学 |
一种30-卤代桦木酸的生产方法
|
|
JP6211527B2
(ja)
|
2011-12-01 |
2017-10-11 |
ハンジョウ ベンシェン ファーマシューティカル シーオー．， エルティーディー．Ｈａｎｇｚｈｏｕ Ｂｅｎｓｈｅｎｇ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｃｏ．， Ｌｔｄ． |
２−置換オレアノール酸誘導体、その調製方法及びその用途
|
|
CN103946231B
(zh)
|
2011-12-01 |
2016-10-26 |
杭州本生药业有限公司 |
齐墩果酸酰胺化衍生物、及其制备方法和应用
|
|
US20150119373A1
(en)
|
2012-04-24 |
2015-04-30 |
Hetero Research Foundation |
Novel betulinic acid derivatives as hiv inhibitors
|
|
US8921419B2
(en)
|
2012-05-08 |
2014-12-30 |
Trustees Of Dartmouth College |
Triterpenoids and compositions containing the same
|
|
US9120839B2
(en)
|
2012-08-14 |
2015-09-01 |
Nexoligo Co., Ltd. |
Ursolic acid derivative and method for preparing same
|
|
CA2882417C
(en)
|
2012-09-10 |
2021-04-20 |
Reata Pharmaceuticals, Inc. |
C17-heteroaryl derivatives of oleanolic acid and methods of use thereof
|
|
US9278912B2
(en)
|
2012-09-10 |
2016-03-08 |
Reata Pharmaceuticals, Inc. |
C13-hydroxy derivatives of oleanolic acid and methods of use thereof
|
|
PL2892912T3
(pl)
|
2012-09-10 |
2019-10-31 |
Reata Pharmaceuticals Inc |
C17-alkanodiylowe i alkenodiylowe pochodne kwasu oleanolowego i sposoby ich zastosowania
|
|
WO2014105926A1
(en)
|
2012-12-31 |
2014-07-03 |
Hetero Research Foundation |
Novel betulinic acid proline derivatives as hiv inhibitors
|
|
CN105102468A
(zh)
|
2013-02-25 |
2015-11-25 |
百时美施贵宝公司 |
用于治疗hiv的c-3烷基和烯基修饰的桦木酸衍生物
|
|
EP2813221A1
(en)
|
2013-06-13 |
2014-12-17 |
Natac Biotech, S.L. |
Combination of pentacyclic triterpenes and hydroxytyrosol and derivatives thereof
|
|
WO2015183794A1
(en)
*
|
2014-05-27 |
2015-12-03 |
City Of Hope |
Tgr5 agonist complexes for treating diabetes and cancer
|
|
WO2015195776A1
(en)
|
2014-06-19 |
2015-12-23 |
Bristol-Myers Squibb Company |
Betulinic acid derivatives with hiv maturation inhibitory activity
|
|
WO2018053123A1
(en)
*
|
2016-09-14 |
2018-03-22 |
Phoenix Biotechnology, Inc. |
Method and compositions for treating viral infection
|
|
MX2020002884A
(es)
*
|
2017-09-14 |
2020-10-05 |
Phoenix Biotechnology Inc |
Método y composición neuroprotectora mejorada para tratar afecciones neurológicas.
|