JP2020531514A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020531514A5 JP2020531514A5 JP2020511214A JP2020511214A JP2020531514A5 JP 2020531514 A5 JP2020531514 A5 JP 2020531514A5 JP 2020511214 A JP2020511214 A JP 2020511214A JP 2020511214 A JP2020511214 A JP 2020511214A JP 2020531514 A5 JP2020531514 A5 JP 2020531514A5
- Authority
- JP
- Japan
- Prior art keywords
- receptor
- rage
- modulator according
- modulator
- cytoplasmic tail
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023121818A JP2023156353A (ja) | 2017-08-22 | 2023-07-26 | 終末糖化産物受容体(rage)の活性化のスクリーニングアッセイ、モジュレーター及び調節 |
| JP2025227130A JP2026062654A (ja) | 2017-08-22 | 2025-12-03 | 終末糖化産物受容体(rage)の活性化のスクリーニングアッセイ、モジュレーター及び調節 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2017903381 | 2017-08-22 | ||
| AU2017903381A AU2017903381A0 (en) | 2017-08-22 | Screening Assays, Modulators and Modulation of Activation of Receptor For Advanced Glycation End-Products (RAGE) | |
| AU2018902298 | 2018-06-26 | ||
| AU2018902298A AU2018902298A0 (en) | 2018-06-26 | Screening Assays, Modulators and Modulation of Activation of Receptor for Advanced Glycation End-Products (RAGE) | |
| PCT/AU2018/050883 WO2019036753A1 (en) | 2017-08-22 | 2018-08-21 | SCREENING TESTS, MODULATORS AND MODULATION OF RECEIVER ACTIVATION FOR ADVANCED GLYCATION TERMINAL PRODUCTS (RAGE) |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023121818A Division JP2023156353A (ja) | 2017-08-22 | 2023-07-26 | 終末糖化産物受容体(rage)の活性化のスクリーニングアッセイ、モジュレーター及び調節 |
| JP2025227130A Division JP2026062654A (ja) | 2017-08-22 | 2025-12-03 | 終末糖化産物受容体(rage)の活性化のスクリーニングアッセイ、モジュレーター及び調節 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020531514A JP2020531514A (ja) | 2020-11-05 |
| JP2020531514A5 true JP2020531514A5 (https=) | 2021-09-30 |
Family
ID=65438276
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020511214A Pending JP2020531514A (ja) | 2017-08-22 | 2018-08-21 | 終末糖化産物受容体(rage)の活性化のスクリーニングアッセイ、モジュレーター及び調節 |
| JP2023121818A Pending JP2023156353A (ja) | 2017-08-22 | 2023-07-26 | 終末糖化産物受容体(rage)の活性化のスクリーニングアッセイ、モジュレーター及び調節 |
| JP2025227130A Pending JP2026062654A (ja) | 2017-08-22 | 2025-12-03 | 終末糖化産物受容体(rage)の活性化のスクリーニングアッセイ、モジュレーター及び調節 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023121818A Pending JP2023156353A (ja) | 2017-08-22 | 2023-07-26 | 終末糖化産物受容体(rage)の活性化のスクリーニングアッセイ、モジュレーター及び調節 |
| JP2025227130A Pending JP2026062654A (ja) | 2017-08-22 | 2025-12-03 | 終末糖化産物受容体(rage)の活性化のスクリーニングアッセイ、モジュレーター及び調節 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US12060408B2 (https=) |
| EP (1) | EP3672982A4 (https=) |
| JP (3) | JP2020531514A (https=) |
| CN (2) | CN120607606A (https=) |
| AU (1) | AU2018322482B2 (https=) |
| CA (1) | CA3109871A1 (https=) |
| WO (1) | WO2019036753A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020531514A (ja) * | 2017-08-22 | 2020-11-05 | モナシュ・ユニヴァーシティ | 終末糖化産物受容体(rage)の活性化のスクリーニングアッセイ、モジュレーター及び調節 |
| KR102203850B1 (ko) * | 2019-04-09 | 2021-01-18 | 사회복지법인 삼성생명공익재단 | 신경교종의 진단 또는 예후 예측용 조성물 및 이에 관한 정보를 제공하는 방법 |
| CN116249787A (zh) | 2020-06-22 | 2023-06-09 | 雷杰纳荣制药公司 | 用g蛋白偶联受体75(gpr75)抑制剂治疗肥胖症 |
| WO2022150709A1 (en) * | 2021-01-11 | 2022-07-14 | President And Fellows Of Harvard College | Compositions and methods for treating viral infection |
| CN113293212A (zh) * | 2021-06-17 | 2021-08-24 | 深圳华因康基因科技有限公司 | 一种检测神经母细胞瘤复发转移基因fzd2扩增的引物探针及其应用 |
| CN113789379B (zh) * | 2021-08-30 | 2022-08-23 | 远见生物科技(上海)有限公司 | 一种检测前列腺癌的诊断试剂盒及其检测方法与应用 |
| JP2023084477A (ja) * | 2021-12-07 | 2023-06-19 | 花王株式会社 | 硫黄化合物を原因とするにおいの抑制剤の評価及び/又は選択方法 |
| KR20230147988A (ko) * | 2022-04-15 | 2023-10-24 | 아주대학교산학협력단 | Rage 길항제 및 age 소거제를 포함하는 당뇨성 뇌졸중 예방 또는 치료용 약학적 조성물 |
| WO2024044659A1 (en) * | 2022-08-24 | 2024-02-29 | Tectonic Therapeutic, Inc. | Constitutively active g protein-coupled receptor compositions and methods of use thereof |
| CN118777620A (zh) * | 2023-04-07 | 2024-10-15 | 浙江友宁生物医药科技有限公司 | Gpr139受体激活检测方法、生理功能评价方法及应用 |
| CN116410335B (zh) * | 2023-04-24 | 2024-08-13 | 徐州医科大学 | 一种多肽tat-mrgprx1c及其应用 |
| CN118755834B (zh) * | 2024-07-15 | 2025-11-18 | 河北医科大学第四医院(河北省肿瘤医院) | 胃癌复发预测模型 |
| CN119901926A (zh) * | 2025-03-31 | 2025-04-29 | 浙江省立同德医院(浙江省精神卫生研究院) | 一种基于rage过表达和spr技术的rage靶向药物筛选方法 |
| CN121695261B (zh) * | 2026-02-11 | 2026-04-17 | 湖南启元生物科技有限公司 | 一种蛋白组合物及其制备方法 |
Family Cites Families (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US5004687A (en) | 1985-05-21 | 1991-04-02 | University Of Georgia Research Foundation, Inc. | Insect virus vector with broadened host range |
| US4868103A (en) | 1986-02-19 | 1989-09-19 | Enzo Biochem, Inc. | Analyte detection by means of energy transfer |
| US5273876A (en) | 1987-06-26 | 1993-12-28 | Syntro Corporation | Recombinant human cytomegalovirus containing foreign gene |
| WO1990009441A1 (en) | 1989-02-01 | 1990-08-23 | The General Hospital Corporation | Herpes simplex virus type i expression vector |
| GB8923123D0 (en) | 1989-10-13 | 1989-11-29 | Connaught Lab | A vaccine for human immunodeficiency virus |
| EP1285967A3 (en) | 1990-09-21 | 2005-03-02 | Chiron Corporation | Human retroviral packaging cell line |
| DE69131908T3 (de) | 1991-02-19 | 2008-04-03 | Oxford Biomedica (Uk) Ltd. | Viruspartikel mit veraendertem wirtspektrum |
| GB9105383D0 (en) | 1991-03-14 | 1991-05-01 | Immunology Ltd | An immunotherapeutic for cervical cancer |
| US6013638A (en) | 1991-10-02 | 2000-01-11 | The United States Of America As Represented By The Department Of Health And Human Services | Adenovirus comprising deletions on the E1A, E1B and E3 regions for transfer of genes to the lung |
| DE69326967T2 (de) | 1992-01-17 | 2000-06-15 | Lakowicz, Joseph R. | Phasenmodulationsenergieübertragungsfluoroimmunassay |
| AU3972893A (en) | 1992-04-03 | 1993-11-08 | Baylor College Of Medicine | Gene therapy using the intestine |
| US6130074A (en) | 1992-06-01 | 2000-10-10 | American Cyanamid Company Five Giralda Farms | Recombinant insect virus with reduced capacity for host-to-host transmission in the environment and methods to produce said virus |
| SE9201984D0 (sv) | 1992-06-29 | 1992-06-29 | Pharmacia Biosensor Ab | Improvement in optical assays |
| JP3147514B2 (ja) | 1992-07-08 | 2001-03-19 | 住友電装株式会社 | 電線送給装置 |
| WO1994012629A1 (en) | 1992-12-02 | 1994-06-09 | Baylor College Of Medicine | Episomal vectors for gene therapy |
| WO1994023048A2 (en) | 1993-04-06 | 1994-10-13 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Gibbon ape leukemia virus-based retroviral vectors |
| US6133028A (en) | 1993-05-28 | 2000-10-17 | Transgene S.A. | Defective adenoviruses and corresponding complementation lines |
| US6120764A (en) | 1993-06-24 | 2000-09-19 | Advec, Inc. | Adenoviruses for control of gene expression |
| US6140087A (en) | 1993-06-24 | 2000-10-31 | Advec, Inc. | Adenovirus vectors for gene therapy |
| EP0728202A4 (en) | 1993-11-12 | 1997-04-23 | Univ Case Western Reserve | EPISOMIC EXPRESSION VECTOR FOR HUMAN GENE THERAPY |
| US5731172A (en) | 1994-03-09 | 1998-03-24 | Sumitomo Pharmaceuticals Company, Ltd. | Recombinant adenovirus and process for producing the same |
| ES2267101T3 (es) | 1994-04-29 | 2007-03-01 | PHARMACIA & UPJOHN COMPANY LLC | Vacuna contra virus de inmunodeficiencia felina. |
| US5604090A (en) | 1994-06-06 | 1997-02-18 | Fred Hutchinson Cancer Research Center | Method for increasing transduction of cells by adeno-associated virus vectors |
| US5662897A (en) | 1994-07-27 | 1997-09-02 | U. Of Ga Research Foundation | Insect viruses, sequences, insecticidal compositions and methods of use |
| US5693508A (en) | 1994-11-08 | 1997-12-02 | Chang; Lung-Ji | Retroviral expression vectors containing MoMLV/CMV-IE/HIV-TAR chimeric long terminal repeats |
| JP3770333B2 (ja) | 1995-03-15 | 2006-04-26 | 大日本住友製薬株式会社 | 組換えdnaウイルスおよびその製造方法 |
| GB9506782D0 (en) | 1995-04-01 | 1995-05-24 | British Biotech Pharm | Retroviral vectors |
| CA2226575C (en) | 1995-07-27 | 2011-10-18 | Genentech, Inc. | Stabile isotonic lyophilized protein formulation |
| AU722196B2 (en) | 1995-08-30 | 2000-07-27 | Genzyme Corporation | Chromatographic purification of adenovirus and AAV |
| US6013516A (en) | 1995-10-06 | 2000-01-11 | The Salk Institute For Biological Studies | Vector and method of use for nucleic acid delivery to non-dividing cells |
| US6020192A (en) | 1996-01-18 | 2000-02-01 | University Of Florida | Humanized green fluorescent protein genes and methods |
| US5874304A (en) | 1996-01-18 | 1999-02-23 | University Of Florida Research Foundation, Inc. | Humanized green fluorescent protein genes and methods |
| JP2000506727A (ja) | 1996-03-05 | 2000-06-06 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 組換え生ネコ免疫不全ウイルスおよびプロウイルスdnaワクチン |
| US5952221A (en) | 1996-03-06 | 1999-09-14 | Avigen, Inc. | Adeno-associated virus vectors comprising a first and second nucleic acid sequence |
| US5891646A (en) | 1997-06-05 | 1999-04-06 | Duke University | Methods of assaying receptor activity and constructs useful in such methods |
| US6156303A (en) | 1997-06-11 | 2000-12-05 | University Of Washington | Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom |
| US6143565A (en) | 1997-08-22 | 2000-11-07 | The United States Of America As Represented By The Secretary Of Agriculture | Stable insect virus-cell expression system |
| US6893827B1 (en) | 2000-02-07 | 2005-05-17 | Applera Corporation | Receptor function assay for G-protein coupled receptors and orphan receptors by reporter enzyme mutant complementation |
| NZ526720A (en) | 2000-12-28 | 2007-11-30 | Altus Pharmaceuticals Inc | Crystallisation of whole antibodies or fragments thereof, on a large scale and a process allowing an alternative route for delivery of therapeutic antibodies |
| WO2003008446A1 (fr) | 2001-07-19 | 2003-01-30 | Mitsubishi Pharma Corporation | Polypeptides se rapportant au transfert de signaux de recepteur de produits terminaux a glycation avancee |
| JP4734498B2 (ja) | 2003-07-09 | 2011-07-27 | ライフ テクノロジーズ コーポレイション | タンパク質−タンパク質相互作用を解析する方法 |
| US7488583B2 (en) | 2003-09-25 | 2009-02-10 | Odyssey Thera, Inc. | Fragment complementation assays for G-protein-coupled receptors and their signaling pathways |
| JP5188804B2 (ja) | 2004-08-03 | 2013-04-24 | トランステック ファーマ,インコーポレイティド | Rage融合タンパク質及びその使用方法 |
| MX2007011411A (es) * | 2005-03-17 | 2007-11-13 | Univ Columbia | Interaccion rage/diaphanous y composiciones relacionadas y metodos. |
| KR100859972B1 (ko) | 2006-02-20 | 2008-09-25 | 이화여자대학교 산학협력단 | 막투과 단백질 도메인 펩타이드 |
| MX2008012023A (es) | 2006-03-21 | 2008-10-01 | Wyeth Corp | Metodos para prevenir y tratar enfermedades amiloidogenicas. |
| DK2080012T3 (da) | 2006-11-10 | 2013-06-17 | Dimerix Bioscience Pty Ltd | Fremgangsmåder til analyse af testforbindelser på forbundne receptorer. |
| US20100249038A1 (en) | 2007-06-12 | 2010-09-30 | Board Of Regents, University Of Texas System | Antagonists of the receptor for advanced glycation end-products (rage) |
| US8101373B2 (en) | 2007-10-12 | 2012-01-24 | Discoverx Corporation | β-galactosidase donor fragments |
| WO2012109569A1 (en) | 2011-02-11 | 2012-08-16 | The Trustees Of Columbia University In The City Of New York | The receptor for advanced glycation endproducts (rage) is a receptor for lysophosphatidic acid (lpa) |
| AU2012260434A1 (en) | 2011-05-23 | 2013-10-31 | Phylogica Limited | Method of determining, identifying or isolating cell-penetrating peptides |
| JP2014527180A (ja) | 2011-09-14 | 2014-10-09 | アベテルノ リミテッド | 細胞内細胞選別 |
| JP2020531514A (ja) * | 2017-08-22 | 2020-11-05 | モナシュ・ユニヴァーシティ | 終末糖化産物受容体(rage)の活性化のスクリーニングアッセイ、モジュレーター及び調節 |
-
2018
- 2018-08-21 JP JP2020511214A patent/JP2020531514A/ja active Pending
- 2018-08-21 AU AU2018322482A patent/AU2018322482B2/en active Active
- 2018-08-21 WO PCT/AU2018/050883 patent/WO2019036753A1/en not_active Ceased
- 2018-08-21 CA CA3109871A patent/CA3109871A1/en active Pending
- 2018-08-21 CN CN202411603566.3A patent/CN120607606A/zh active Pending
- 2018-08-21 US US16/641,174 patent/US12060408B2/en active Active
- 2018-08-21 CN CN201880068213.4A patent/CN111247163B/zh active Active
- 2018-08-21 EP EP18849151.8A patent/EP3672982A4/en active Pending
-
2023
- 2023-07-26 JP JP2023121818A patent/JP2023156353A/ja active Pending
-
2024
- 2024-08-13 US US18/802,964 patent/US20250019415A1/en active Pending
-
2025
- 2025-12-03 JP JP2025227130A patent/JP2026062654A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2020531514A5 (https=) | ||
| Toro et al. | MaxiK channel and cell signalling | |
| JP7212009B2 (ja) | Cxcr4結合分子 | |
| EP2970415B1 (en) | Apelin fusion proteins and uses thereof | |
| CA2586344C (en) | G protein coupled receptor agonists and antagonists and methods of use | |
| AU2006212813B2 (en) | Compositions and methods related to soluble G-protein coupled receptors (sGPCRs) | |
| JP2024010090A (ja) | リラキシン融合ポリペプチドおよびその使用 | |
| Kolakowski Jr et al. | Probing the “Message: Address” Sites for Chemoattractant Binding to the C5a Receptor: MUTAGENESIS OF HYDROPHILIC AND PROLINE RESIDUES WITHIN THE TRANSMEMBRANE SEGMENTS | |
| Lin et al. | Comparison of the peptide structural requirements for high affinity interaction with bombesin receptors | |
| CA2534748C (en) | Relaxin superfamily peptide analogues | |
| CN114591415B (zh) | Glp-1/gcg双受体激动剂多肽及其融合蛋白 | |
| Fan et al. | Molecular mechanism and structural basis of interactions of dipeptidyl peptidase IV with adenosine deaminase and human immunodeficiency virus type-1 transcription transactivator | |
| US20120214744A1 (en) | Polypeptides and nucleic acids for treating erbb2-dependent cancers | |
| Lin et al. | GPS proteolytic cleavage of adhesion-GPCRs | |
| JP2011526491A (ja) | インスリン融合ポリペプチド | |
| Bermak et al. | Accessory proteins in the biogenesis of G protein-coupled receptors | |
| Schneider et al. | Histamine H4 receptor–RGS fusion proteins expressed in Sf9 insect cells: A sensitive and reliable approach for the functional characterization of histamine H4 receptor ligands | |
| EP1292677A2 (en) | Human hm74-like g protein coupled receptor | |
| US20080206231A1 (en) | Compositions and Methods for Treating Disease | |
| Zaidi et al. | Molecular and clinical pharmacology of calcitonin | |
| WO2020118363A1 (en) | Screening assays, modulators and modulation of intracellular signalling mediated by immunoglobulin superfamily cell adhesion molecules | |
| Li et al. | Molecular cloning and functional characterization of a type-I neurotensin receptor (NTR) and a novel NTR from the bullfrog brain | |
| WO2022140852A1 (en) | Stim proteins couple nmda receptors to pannexin 1 activation | |
| Lallement et al. | Cholecystokinin and gastrin are not equally sensitive to GTPγS at CCKB receptors: importance of the sulphated tyrosine | |
| Tomasovic et al. | Role of Cbl-associated protein/ponsin in receptor tyrosine kinase signaling and cell adhesion |