JP2020530993A5 - - Google Patents
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- JP2020530993A5 JP2020530993A5 JP2020505194A JP2020505194A JP2020530993A5 JP 2020530993 A5 JP2020530993 A5 JP 2020530993A5 JP 2020505194 A JP2020505194 A JP 2020505194A JP 2020505194 A JP2020505194 A JP 2020505194A JP 2020530993 A5 JP2020530993 A5 JP 2020530993A5
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- JP
- Japan
- Prior art keywords
- nucleic acid
- acid sequence
- cell
- expressed
- noi
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023057340A JP2023076572A (ja) | 2017-08-02 | 2023-03-31 | キメラ抗原受容体または改変tcrを発現し、選択的に発現されるヌクレオチド配列を含む細胞 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1712407.4A GB201712407D0 (en) | 2017-08-02 | 2017-08-02 | Cell |
| GB1712407.4 | 2017-08-02 | ||
| GBGB1806372.7A GB201806372D0 (en) | 2018-04-19 | 2018-04-19 | Cell |
| GB1806372.7 | 2018-04-19 | ||
| PCT/GB2018/052204 WO2019025800A1 (en) | 2017-08-02 | 2018-08-01 | CELLS EXPRESSING A CHIMERIC ANTIGENIC RECEPTOR OR A MANIPULATED TCR AND COMPRISING A SELECTIVELY EXPRESSED SELECTIVE NUCLEOTIDE SEQUENCE |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023057340A Division JP2023076572A (ja) | 2017-08-02 | 2023-03-31 | キメラ抗原受容体または改変tcrを発現し、選択的に発現されるヌクレオチド配列を含む細胞 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020530993A JP2020530993A (ja) | 2020-11-05 |
| JP2020530993A5 true JP2020530993A5 (enExample) | 2021-07-26 |
Family
ID=63371717
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020505194A Pending JP2020530993A (ja) | 2017-08-02 | 2018-08-01 | キメラ抗原受容体または改変tcrを発現し、選択的に発現されるヌクレオチド配列を含む細胞 |
| JP2023057340A Pending JP2023076572A (ja) | 2017-08-02 | 2023-03-31 | キメラ抗原受容体または改変tcrを発現し、選択的に発現されるヌクレオチド配列を含む細胞 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023057340A Pending JP2023076572A (ja) | 2017-08-02 | 2023-03-31 | キメラ抗原受容体または改変tcrを発現し、選択的に発現されるヌクレオチド配列を含む細胞 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20210130775A1 (enExample) |
| EP (1) | EP3662055A1 (enExample) |
| JP (2) | JP2020530993A (enExample) |
| CN (1) | CN111164203A (enExample) |
| AU (1) | AU2018311345A1 (enExample) |
| CA (1) | CA3071495A1 (enExample) |
| WO (1) | WO2019025800A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3893923A2 (en) * | 2018-12-14 | 2021-10-20 | Autolus Limited | Cell |
| AU2020232789B2 (en) * | 2019-03-06 | 2026-04-09 | Lentigen Technology, Inc. | Compositions and methods for treating cancer with self-driving chimeric antigen receptors |
| EP3934666A1 (en) | 2019-03-08 | 2022-01-12 | Autolus Limited | Compositions and methods comprising engineered chimeric antigen receptor and modulator of car |
| WO2021028359A1 (en) * | 2019-08-09 | 2021-02-18 | Sangamo Therapeutics France | Controlled expression of chimeric antigen receptors in t cells |
| EP4017510A4 (en) * | 2019-08-20 | 2023-11-22 | Senti Biosciences, Inc. | CHIMERIC INHIBITOR RECEPTOR |
| CN120605327A (zh) * | 2019-11-06 | 2025-09-09 | 贝勒医学院 | 用于产生细胞毒性效应子记忆t细胞以用于癌症的t细胞治疗的方法 |
| CA3176697A1 (en) * | 2020-05-11 | 2021-11-18 | Doughlas J. JOLLY | Vectors and methods for in vivo transduction |
| GB202013466D0 (en) * | 2020-08-27 | 2020-10-14 | Inst De Medicina Molecular Joaeo Lobo Antunes | Genetic construct |
| EP4455157A1 (en) * | 2023-04-27 | 2024-10-30 | Fundacion Publica Andaluza Progreso Y Salud M.P.- Fps | Polynuceotide for t cell specific transgene expression |
| WO2025226608A1 (en) * | 2024-04-22 | 2025-10-30 | The Johns Hopkins University | Immunotoxin-armored immune effector cells and uses thereof |
| WO2026085295A1 (en) * | 2024-10-16 | 2026-04-23 | The Cleveland Clinic Foundation | Kynurenine responsive and degrading bacteria |
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| PT2126054T (pt) | 2007-01-31 | 2016-10-12 | Yeda Res & Dev | Células t reguladoras geneticamente modificadas, redirecionadas e sua utilização na supressão de doenças inflamatórias e autoimunitárias |
| JP5934099B2 (ja) * | 2009-10-01 | 2016-06-15 | アメリカ合衆国 | 抗血管内皮増殖因子受容体−2キメラ抗原受容体及び癌の治療のためのその使用 |
| GB201206559D0 (en) * | 2012-04-13 | 2012-05-30 | Ucl Business Plc | Polypeptide |
| US10117896B2 (en) * | 2012-10-05 | 2018-11-06 | The Trustees Of The University Of Pennsylvania | Use of a trans-signaling approach in chimeric antigen receptors |
| SG11201505896YA (en) * | 2013-02-20 | 2015-09-29 | Novartis Ag | Treatment of cancer using humanized anti-egfrviii chimeric antigen receptor |
| UY35468A (es) * | 2013-03-16 | 2014-10-31 | Novartis Ag | Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19 |
| GB201317929D0 (en) * | 2013-10-10 | 2013-11-27 | Ucl Business Plc | Chimeric antigen receptor |
| EP3858379A1 (en) * | 2013-11-21 | 2021-08-04 | Autolus Limited | Cell |
| WO2015092024A2 (en) * | 2013-12-20 | 2015-06-25 | Cellectis | Method of engineering multi-input signal sensitive t cell for immunotherapy |
| GB201322798D0 (en) * | 2013-12-20 | 2014-02-05 | Oxford Biomedica Ltd | Production system |
| US11385233B2 (en) * | 2015-03-05 | 2022-07-12 | Autolus Limited | Methods of depleting malignant T-cells |
| RU2744046C2 (ru) * | 2014-03-05 | 2021-03-02 | Отолус Лимитед | ХИМЕРНЫЙ АНТИГЕННЫЙ РЕЦЕПТОР (CAR) С АНТИГЕНСВЯЗЫВАЮЩИМИ ДОМЕНАМИ К КОНСТАНТНОЙ ОБЛАСТИ β Т-КЛЕТОЧНОГО РЕЦЕПТОРА |
| GB201403972D0 (en) * | 2014-03-06 | 2014-04-23 | Ucl Business Plc | Chimeric antigen receptor |
| GB201405845D0 (en) * | 2014-04-01 | 2014-05-14 | Ucl Business Plc | Signalling system |
| GB201415347D0 (en) * | 2014-08-29 | 2014-10-15 | Ucl Business Plc | Signalling system |
| HRP20240357T1 (hr) * | 2014-12-24 | 2024-06-07 | Autolus Limited | Stanica |
| GB201501936D0 (en) * | 2015-02-05 | 2015-03-25 | Ucl Business Plc | Signalling system |
| GB201503133D0 (en) * | 2015-02-24 | 2015-04-08 | Ucl Business Plc And Syncona Partners Llp | Chimeric protein |
| GB201503742D0 (en) * | 2015-03-05 | 2015-04-22 | Ucl Business Plc | Chimeric antigen receptor |
| GB201504840D0 (en) * | 2015-03-23 | 2015-05-06 | Ucl Business Plc | Chimeric antigen receptor |
| GB201507108D0 (en) * | 2015-04-27 | 2015-06-10 | Ucl Business Plc | Nucleic acid construct |
| GB201507119D0 (en) * | 2015-04-27 | 2015-06-10 | Ucl Business Plc | Nucleic Acid Construct |
| GB201507115D0 (en) * | 2015-04-27 | 2015-06-10 | Ucl Business Plc | Nucleic Acid Construct |
| GB201507111D0 (en) * | 2015-04-27 | 2015-06-10 | Ucl Business Plc | Nucleic acid construct |
| GB201507368D0 (en) * | 2015-04-30 | 2015-06-17 | Ucl Business Plc | Cell |
| MX2017015239A (es) * | 2015-05-29 | 2018-02-19 | Juno Therapeutics Inc | Composicion y metodos para regular interacciones inhibitorias en celulas geneticamente modificadas. |
| GB201514874D0 (en) * | 2015-08-20 | 2015-10-07 | Autolus Ltd | Cell |
| US10286092B2 (en) * | 2015-08-25 | 2019-05-14 | Ucl Business Plc | Detecting a therapeutic cell |
| US11098283B2 (en) * | 2015-08-25 | 2021-08-24 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | T cells modified to overexpress c-Myb |
| WO2017040324A1 (en) * | 2015-08-28 | 2017-03-09 | The Trustees Of The University Of Pennsylvania | Methods and compositions for cells expressing a chimeric intracellular signaling molecule |
| JP7054924B2 (ja) * | 2015-09-23 | 2022-04-15 | サイトイミューン セラピューティクス, インコーポレイテッド | 免疫療法のためのflt3指向car細胞 |
| GB201518817D0 (en) * | 2015-10-23 | 2015-12-09 | Autolus Ltd | Cell |
| WO2017075537A1 (en) * | 2015-10-30 | 2017-05-04 | Aleta Biotherapeutics Inc. | Compositions and methods for treatment of cancer |
| GB201519900D0 (en) * | 2015-11-11 | 2015-12-23 | Ucl Business Plc | Chimeric antigen receptor |
| WO2017133175A1 (en) * | 2016-02-04 | 2017-08-10 | Nanjing Legend Biotech Co., Ltd. | Engineered mammalian cells for cancer therapy |
| GB201609604D0 (en) * | 2016-06-01 | 2016-07-13 | Ucl Business Plc | Cell |
| GB201610512D0 (en) * | 2016-06-16 | 2016-08-03 | Autolus Ltd | Chimeric antigen receptor |
| GB201610515D0 (en) * | 2016-06-16 | 2016-08-03 | Autolus Ltd | Cell |
| CA2937157A1 (en) * | 2016-07-25 | 2018-01-25 | Ucl Business Ltd | Protein-based t-cell receptor knockdown |
| US20180064758A1 (en) * | 2016-09-05 | 2018-03-08 | Ucl Business Plc | Chimeric antigen receptor |
| SG11201901757YA (en) * | 2016-09-08 | 2019-03-28 | Bluebird Bio Inc | Pd-1 homing endonuclease variants, compositions, and methods of use |
| CA3042613A1 (en) * | 2016-11-11 | 2018-05-17 | Autolus Limited | Chimeric antigen receptor |
| GB201621891D0 (en) * | 2016-12-21 | 2017-02-01 | Autolus Ltd | Transcription system |
| WO2018193231A1 (en) * | 2017-04-18 | 2018-10-25 | Autolus Limited | Cell |
| GB201707779D0 (en) * | 2017-05-15 | 2017-06-28 | Autolus Ltd | Cell |
| CA3063695A1 (en) * | 2017-05-17 | 2018-11-22 | Seattle Children's Hospital (Dba Seattle Children's Research Institute | Generating mammalian t cell activation inducible synthetic promoters (syn+pro) to improve t cell therapy |
| GB201716728D0 (en) * | 2017-10-12 | 2017-11-29 | Autolus Ltd | Cell |
| JP7621795B2 (ja) * | 2017-10-19 | 2025-01-27 | セレクティス | 改善された免疫細胞療法のためのnk阻害物質遺伝子の標的指向遺伝子組み込み |
| GB201718697D0 (en) * | 2017-11-13 | 2017-12-27 | Autolus Ltd | Cell |
| GB201800298D0 (en) * | 2018-01-09 | 2018-02-21 | Autolus Ltd | Method |
| GB201807862D0 (en) * | 2018-05-15 | 2018-06-27 | Ucl Business Plc | Chimeric antigen receptor |
| WO2019220109A1 (en) * | 2018-05-15 | 2019-11-21 | Autolus Limited | Chimeric antigen receptor |
| GB201807870D0 (en) * | 2018-05-15 | 2018-06-27 | Autolus Ltd | A CD79-specific chimeric antigen receptor |
| SG11202102781UA (en) * | 2018-09-27 | 2021-04-29 | Autolus Ltd | Chimeric antigen receptor |
| GB201816522D0 (en) * | 2018-10-10 | 2018-11-28 | Autolus Ltd | Methods and reagents for analysing nucleic acids from single cells |
| EP3893923A2 (en) * | 2018-12-14 | 2021-10-20 | Autolus Limited | Cell |
| EP3934666A1 (en) * | 2019-03-08 | 2022-01-12 | Autolus Limited | Compositions and methods comprising engineered chimeric antigen receptor and modulator of car |
| GB201906202D0 (en) * | 2019-05-02 | 2019-06-19 | Autolus Ltd | Cell |
| GB201910651D0 (en) * | 2019-07-25 | 2019-09-11 | Autolus Ltd | Virus-like particle |
-
2018
- 2018-08-01 WO PCT/GB2018/052204 patent/WO2019025800A1/en not_active Ceased
- 2018-08-01 AU AU2018311345A patent/AU2018311345A1/en not_active Abandoned
- 2018-08-01 CN CN201880062710.3A patent/CN111164203A/zh active Pending
- 2018-08-01 JP JP2020505194A patent/JP2020530993A/ja active Pending
- 2018-08-01 CA CA3071495A patent/CA3071495A1/en not_active Abandoned
- 2018-08-01 US US16/635,740 patent/US20210130775A1/en not_active Abandoned
- 2018-08-01 EP EP18759677.0A patent/EP3662055A1/en not_active Withdrawn
-
2023
- 2023-03-31 JP JP2023057340A patent/JP2023076572A/ja active Pending
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