JP2020529838A5 - - Google Patents
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- JP2020529838A5 JP2020529838A5 JP2019572402A JP2019572402A JP2020529838A5 JP 2020529838 A5 JP2020529838 A5 JP 2020529838A5 JP 2019572402 A JP2019572402 A JP 2019572402A JP 2019572402 A JP2019572402 A JP 2019572402A JP 2020529838 A5 JP2020529838 A5 JP 2020529838A5
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- JP
- Japan
- Prior art keywords
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- acid sequence
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1710836.6A GB201710836D0 (en) | 2017-07-05 | 2017-07-05 | ROR1 Car T-Cells |
| GB1710836.6 | 2017-07-05 | ||
| PCT/GB2018/051915 WO2019008378A1 (en) | 2017-07-05 | 2018-07-05 | Ror1 car t-cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020529838A JP2020529838A (ja) | 2020-10-15 |
| JP2020529838A5 true JP2020529838A5 (enExample) | 2021-08-12 |
| JP7179030B2 JP7179030B2 (ja) | 2022-11-28 |
Family
ID=59592474
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019572402A Expired - Fee Related JP7179030B2 (ja) | 2017-07-05 | 2018-07-05 | Ｒｏｒ１ ｃａｒ ｔ細胞 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US11723925B2 (enExample) |
| EP (1) | EP3649150B1 (enExample) |
| JP (1) | JP7179030B2 (enExample) |
| CN (1) | CN110997709B (enExample) |
| AU (1) | AU2018295478A1 (enExample) |
| CA (1) | CA3068197A1 (enExample) |
| GB (1) | GB201710836D0 (enExample) |
| MX (1) | MX2019015352A (enExample) |
| WO (1) | WO2019008378A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201710835D0 (en) * | 2017-07-05 | 2017-08-16 | Ucl Business Plc | ROR1 Antibodies |
| CN108441505B (zh) * | 2018-05-28 | 2023-07-07 | 上海恒润达生生物科技股份有限公司 | 一种靶向ror1的嵌合抗原受体及其用途 |
| WO2021057823A1 (en) * | 2019-09-27 | 2021-04-01 | Immuther Pharmtech (Shanghai) Co., Ltd. | Ror1 specific chimeric antigen receptors and their therapeutic applications |
| IL300760A (en) * | 2020-08-24 | 2023-04-01 | Epimab Biotherapeutics Hk Ltd | Anti-ROR1 antibodies and related bispecific binding proteins |
| AU2022227686A1 (en) | 2021-02-25 | 2023-07-27 | Lyell Immunopharma, Inc. | Ror1 targeting chimeric antigen receptor |
| JP2024540099A (ja) | 2021-10-28 | 2024-10-31 | ライエル・イミュノファーマ・インコーポレイテッド | Ｒｏｒ１結合タンパク質を発現する細胞を培養する方法 |
| CN114133457B (zh) * | 2021-12-08 | 2022-08-19 | 郑州源创吉因实业有限公司 | 一种靶向ror1和cd33的双特异性嵌合抗原受体(car)及其应用 |
| CN118974090A (zh) * | 2022-04-02 | 2024-11-15 | 山东先声生物制药有限公司 | 抗ror1的抗体及其用途 |
| WO2024064952A1 (en) | 2022-09-23 | 2024-03-28 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells overexpressing c-jun |
| WO2024064958A1 (en) | 2022-09-23 | 2024-03-28 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells |
| WO2024077174A1 (en) | 2022-10-05 | 2024-04-11 | Lyell Immunopharma, Inc. | Methods for culturing nr4a-deficient cells |
| CN118440200B (zh) * | 2023-04-21 | 2025-05-16 | 星奕昂(上海)生物科技有限公司 | 靶向ror1的抗体及其应用 |
| WO2025006880A1 (en) * | 2023-06-29 | 2025-01-02 | Caribou Biosciences, Inc. | Diagnostic and therapeutic methods for use with ror1 antagonists |
| US20250127728A1 (en) | 2023-10-05 | 2025-04-24 | Capstan Therapeutics, Inc. | Constrained Ionizable Cationic Lipids and Lipid Nanoparticles |
| WO2025076113A1 (en) | 2023-10-05 | 2025-04-10 | Capstan Therapeutics, Inc. | Ionizable cationic lipids with conserved spacing and lipid nanoparticles |
| WO2025217398A1 (en) | 2024-04-10 | 2025-10-16 | Lyell Immunopharma, Inc. | Methods for culturing cells with improved culture medium |
| WO2025217452A1 (en) | 2024-04-11 | 2025-10-16 | Capstan Therapeutics, Inc. | Constrained ionizable cationic lipids and lipid nanoparticles |
| WO2025217454A2 (en) | 2024-04-11 | 2025-10-16 | Capstan Therapeutics, Inc. | Ionizable cationic lipids and lipid nanoparticles |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0920798A (ja) * | 1995-07-11 | 1997-01-21 | Asahi Chem Ind Co Ltd | ヒト抗ＨＢｓ抗体 |
| US8076459B2 (en) | 2003-10-16 | 2011-12-13 | Micromet Ag | Multispecfic deimmunized CD3-binders |
| BRPI0607315B1 (pt) * | 2005-02-07 | 2022-05-17 | Roche Glycart Ag | Molécula de ligação ao antígeno anti-egfr humanizada e seus usos, composição farmacêutica, e método para detectar a presença de egfr em uma amostra |
| WO2007146957A2 (en) | 2006-06-13 | 2007-12-21 | Irm Llc | Ror1 as a therapeutic target for lung cancer |
| US9316646B2 (en) | 2009-04-23 | 2016-04-19 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Anti-human ROR1 antibodies |
| MX2011012047A (es) * | 2009-05-13 | 2011-12-14 | Genzyme Corp | Inmunoglobulinas humanas anti-cd52. |
| WO2011054007A1 (en) | 2009-11-02 | 2011-05-05 | Oxford Biotherapeutics Ltd. | Ror1 as therapeutic and diagnostic target |
| US9150647B2 (en) | 2009-12-18 | 2015-10-06 | Kancera Ab | Biological inhibitors of ROR1 capable of inducing cell death |
| US9228023B2 (en) | 2010-10-01 | 2016-01-05 | Oxford Biotherapeutics Ltd. | Anti-ROR1 antibodies and methods of use for treatment of cancer |
| EP2646469B1 (en) | 2010-12-01 | 2017-11-01 | The United States of America, as represented by The Secretary, Department of Health and Human Services | Chimeric rabbit/human ror1 antibodies |
| GB201020995D0 (en) | 2010-12-10 | 2011-01-26 | Bioinvent Int Ab | Biological materials and uses thereof |
| EP3252076B1 (en) | 2011-01-14 | 2019-09-04 | The Regents Of The University Of California | Diagnostic use of antibodies against ror-1 protein |
| LT2884999T (lt) * | 2012-08-20 | 2021-04-12 | Fred Hutchinson Cancer Research Center | Ląstelinės imunoterapijos būdas ir kompozicijos |
| PL3489261T3 (pl) * | 2012-08-24 | 2021-08-16 | The Regents Of The University Of California | Przeciwciała i szczepionki do stosowania w leczeniu nowotworów z ekspresją ROR1 i w hamowaniu przerzutu |
| US20160017058A1 (en) * | 2013-03-14 | 2016-01-21 | The California Institute For Biomedical Research | Bispecific antibodies and uses thereof |
| EP2789630A1 (en) | 2013-04-09 | 2014-10-15 | EngMab AG | Bispecific antibodies against CD3e and ROR1 |
| US10647768B2 (en) | 2014-05-29 | 2020-05-12 | Macrogenics, Inc. | Multi-chain polypeptide-containing tri-specific binding molecules |
| US10752684B2 (en) * | 2014-07-29 | 2020-08-25 | Cellectis | ROR1 (NTRKR1) specific chimeric antigen receptors for cancer immunotherapy |
| WO2016016343A1 (en) | 2014-07-31 | 2016-02-04 | Cellectis | Ror1 specific multi-chain chimeric antigen receptor |
| AU2015313268B2 (en) | 2014-09-08 | 2018-12-20 | National Cancer Center | Cancer-cell-specific antibody, anticancer agent, and cancer testing method |
| EP3204415B1 (en) | 2014-10-09 | 2020-06-17 | EngMab Sàrl | Bispecific antibodies against cd3epsilon and ror1 |
| JP2017536341A (ja) | 2014-10-09 | 2017-12-07 | エンクマフ アーゲー | 卵巣がんの処置における使用のためのＣＤ３εおよびＲＯＲ１に対する二特異性抗体 |
| WO2016094873A2 (en) | 2014-12-12 | 2016-06-16 | Emergent Product Development Seattle, Llc | Receptor tyrosine kinase-like orphan receptor 1 binding proteins and related compositions and methods |
| RU2751362C2 (ru) * | 2014-12-29 | 2021-07-13 | Новартис Аг | Способы получения экспрессирующих химерный антигенный рецептор клеток |
| US20160208018A1 (en) * | 2015-01-16 | 2016-07-21 | Juno Therapeutics, Inc. | Antibodies and chimeric antigen receptors specific for ror1 |
| EP3253754B1 (en) | 2015-02-02 | 2021-03-31 | Kancera AB | 2-phenyl-3h-imidazo[4,5-b]pyridine derivates useful as inhibitors of mammalian tyrosine kinase ror1 activity |
| EP3283528B1 (en) * | 2015-04-14 | 2021-07-21 | Academia Sinica | Anti-vegfr2 human antibody for anti-angiogenic and targeted cancer therapy |
| CN108137669B (zh) * | 2015-05-18 | 2023-02-17 | 优瑞科生物技术公司 | 抗ror1嵌合抗原受体 |
| HK1253507A1 (zh) | 2015-05-18 | 2019-06-21 | Eureka Therapeutics, Inc. | 抗 ror1 抗体 |
| CA3001941A1 (en) | 2015-10-30 | 2017-05-04 | Nbe-Therapeutics Ag | Anti-ror1 antibodies |
| MX2018008926A (es) | 2016-01-20 | 2019-01-10 | Scripps Research Inst | Composiciones de anticuerpo contra ror1 y métodos relacionados. |
| CA3011419A1 (en) | 2016-01-22 | 2017-07-27 | Janssen Biotech, Inc. | Anti-ror1 antibodies, ror1 x cd3 bispecific antibodies, and methods of using the same |
| AR108034A1 (es) | 2016-02-17 | 2018-07-11 | Macrogenics Inc | Moléculas de unión a ror1, y métodos de uso de las mismas |
| WO2017156479A1 (en) | 2016-03-11 | 2017-09-14 | Bluebird Bio, Inc. | Ror1 chimeric antigen receptors |
| US11008318B2 (en) | 2016-07-11 | 2021-05-18 | Kancera Ab | 2-phenylimidazo[4,5-b]pyridin-7-amine derivates useful as inhibitors of mammalian tyrosine kinase ROR1 activity |
| US20200338210A1 (en) | 2016-12-22 | 2020-10-29 | Ardeagen Corporation | Anti-ror1 antibody and conjugates thereof |
| AU2018271872A1 (en) | 2017-05-23 | 2019-12-12 | Dragonfly Therapeutics, Inc. | A protein binding NKG2D, CD16 and ROR1 or ROR2 |
| TWI804499B (zh) | 2017-06-23 | 2023-06-11 | 美商維洛斯生物公司 | Ror1抗體免疫接合物 |
| EP3645741A4 (en) | 2017-06-25 | 2021-08-25 | Systimmune, Inc. | ANTI-4-1BB ANTIBODIES AND METHOD OF MANUFACTURING AND USING |
| GB201710835D0 (en) * | 2017-07-05 | 2017-08-16 | Ucl Business Plc | ROR1 Antibodies |
| US20210139579A1 (en) | 2017-07-20 | 2021-05-13 | Nbe-Therapeutics Ag | Multispecific antibody product that binds to different ror1 epitopes |
| KR20230008269A (ko) | 2017-08-07 | 2023-01-13 | 엔비이-테라퓨틱스 아게 | 생체 내 내성이 높은 항체 약물 결합체 |
| CN117756946A (zh) | 2017-11-03 | 2024-03-26 | 莱蒂恩技术公司 | 用于用抗ror1免疫治疗来治疗癌症的组合物和方法 |
| GB201721802D0 (en) | 2017-12-22 | 2018-02-07 | Almac Discovery Ltd | Ror1-specific antigen binding molecules |
| WO2019225777A1 (ko) | 2018-05-23 | 2019-11-28 | 에이비엘바이오 주식회사 | 항-ror1 항체 및 그 용도 |
| US11723926B2 (en) * | 2019-09-27 | 2023-08-15 | Starkage Therapeutics | Senescent cell-associated antigen-binding domains, antibodies and chimeric antigen receptors comprising the same, and uses thereof |
-
2017
- 2017-07-05 GB GBGB1710836.6A patent/GB201710836D0/en not_active Ceased
-
2018
- 2018-07-05 CA CA3068197A patent/CA3068197A1/en active Pending
- 2018-07-05 AU AU2018295478A patent/AU2018295478A1/en not_active Abandoned
- 2018-07-05 US US16/628,450 patent/US11723925B2/en active Active
- 2018-07-05 CN CN201880045348.9A patent/CN110997709B/zh not_active Expired - Fee Related
- 2018-07-05 WO PCT/GB2018/051915 patent/WO2019008378A1/en not_active Ceased
- 2018-07-05 EP EP18742576.4A patent/EP3649150B1/en active Active
- 2018-07-05 JP JP2019572402A patent/JP7179030B2/ja not_active Expired - Fee Related
- 2018-07-05 MX MX2019015352A patent/MX2019015352A/es unknown
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