JP2020528138A5 - - Google Patents
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- Publication number
- JP2020528138A5 JP2020528138A5 JP2020501172A JP2020501172A JP2020528138A5 JP 2020528138 A5 JP2020528138 A5 JP 2020528138A5 JP 2020501172 A JP2020501172 A JP 2020501172A JP 2020501172 A JP2020501172 A JP 2020501172A JP 2020528138 A5 JP2020528138 A5 JP 2020528138A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- gdf15
- acid sequence
- gdf15 protein
- test sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000000597 Growth Differentiation Factor 15 Human genes 0.000 claims description 19
- 108010041834 Growth Differentiation Factor 15 Proteins 0.000 claims description 19
- 238000012360 testing method Methods 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 6
- 230000000694 effects Effects 0.000 claims description 5
- 102000004169 proteins and genes Human genes 0.000 claims description 4
- 108090000623 proteins and genes Proteins 0.000 claims description 4
- 238000012216 screening Methods 0.000 claims description 4
- 208000008338 non-alcoholic fatty liver disease Diseases 0.000 claims 6
- 239000000203 mixture Substances 0.000 claims 5
- 239000000523 sample Substances 0.000 claims 5
- 125000003275 alpha amino acid group Chemical group 0.000 claims 3
- 239000012472 biological sample Substances 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 208000019425 cirrhosis of liver Diseases 0.000 claims 2
- 206010016654 Fibrosis Diseases 0.000 claims 1
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
- 238000001574 biopsy Methods 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 230000004761 fibrosis Effects 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 210000004185 liver Anatomy 0.000 claims 1
- 150000007523 nucleic acids Chemical group 0.000 claims 1
- 208000019423 liver disease Diseases 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000002265 prevention Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020170105714A KR102010652B1 (ko) | 2017-08-21 | 2017-08-21 | 간질환 예측 또는 진단용 조성물 및 이를 이용한 간질환 예측 또는 진단 방법 |
| KR10-2017-0105714 | 2017-08-21 | ||
| PCT/KR2018/009548 WO2019039817A2 (ko) | 2017-08-21 | 2018-08-20 | 간질환 예측 또는 진단용 조성물 및 이를 이용한 간질환 예측 또는 진단 방법 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020528138A JP2020528138A (ja) | 2020-09-17 |
| JP2020528138A5 true JP2020528138A5 (enExample) | 2021-04-08 |
| JP7053783B2 JP7053783B2 (ja) | 2022-04-12 |
Family
ID=65439516
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020501172A Active JP7053783B2 (ja) | 2017-08-21 | 2018-08-20 | 肝疾患予測又は診断用組成物及びこれを用いた肝疾患予測又は診断方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20200292553A1 (enExample) |
| EP (1) | EP3674710B1 (enExample) |
| JP (1) | JP7053783B2 (enExample) |
| KR (1) | KR102010652B1 (enExample) |
| CN (1) | CN111316103B (enExample) |
| WO (1) | WO2019039817A2 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12372530B2 (en) * | 2017-11-15 | 2025-07-29 | Beth Israel Deaconess Medical Center, Inc. | Markers for the diagnosis and treatment of non-alcoholic steatohepatitis (NASH) and advanced liver fibrosis |
| KR102569644B1 (ko) | 2020-10-30 | 2023-08-23 | 가톨릭대학교 산학협력단 | Gdf15를 유효성분으로 함유하는 면역질환의 예방 및 치료용 조성물 |
| CN113160983A (zh) * | 2021-04-09 | 2021-07-23 | 南京医科大学附属逸夫医院 | 一种代谢相关脂肪性肝病临床预测模型 |
| US20240344134A1 (en) * | 2021-07-26 | 2024-10-17 | Osaka University | Diagnostic marker for hepatic cancer development in chronic hepatic disease |
| WO2023008673A1 (ko) * | 2021-07-30 | 2023-02-02 | 숙명여자대학교산학협력단 | 머신러닝 기반 비알코올성 지방간염 판별용 복합 마커 및 이의 용도 |
| CN115948563A (zh) * | 2023-03-13 | 2023-04-11 | 中国医学科学院北京协和医院 | 蛋白标志物的检测试剂在制备诊断肝癌的产品中的应用 |
| KR20250071598A (ko) | 2023-11-15 | 2025-05-22 | 주식회사 아이도트 | 장내미생물 중 전체 레벨의 데이터를 이용하는 간 질환 진단 시스템 및 방법 |
| KR20250074386A (ko) | 2023-11-20 | 2025-05-27 | 주식회사 아이도트 | 장내 미생물 중 전체 레벨의 데이터를 이용하는 간 질환 진단을 위한 학습 시스템 및 방법 |
| KR20250075910A (ko) | 2023-11-22 | 2025-05-29 | 주식회사 아이도트 | 장내 미생물 중 종 레벨의 데이터를 이용하는 간 질환 진단 시스템 및 방법 |
| KR20250077720A (ko) | 2023-11-24 | 2025-06-02 | 주식회사 아이도트 | 장내 미생물 중 종 레벨의 데이터를 이용하는 간 질환 진단 위한 학습 시스템 및 방법 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7157235B2 (en) | 2002-06-17 | 2007-01-02 | St. Vincent's Hospital Sydney Limited | Methods of diagnosis, prognosis and treatment of cardiovascular disease |
| US20070237713A1 (en) | 2006-04-04 | 2007-10-11 | Fan Rong A | PCan065 Antibody Compositions and Methods of Use |
| EP2209003A1 (en) * | 2009-01-16 | 2010-07-21 | F. Hoffmann-Roche AG | Means and methods for differentiating between fibrosis and cirrhosis |
| EP2211182A1 (en) | 2009-01-16 | 2010-07-28 | Roche Diagnostics GmbH | Method for the assessment of severity of liver cirrhosis |
| JP5636567B2 (ja) | 2010-10-13 | 2014-12-10 | 学校法人東京女子医科大学 | 脂肪性肝疾患を診断するためのバイオマーカー、その測定方法、コンピュータプログラム、および、記憶媒体 |
| EP3590537A1 (en) | 2012-09-26 | 2020-01-08 | Julius-Maximilians-Universität Würzburg | Monoclonal antibodies to growth and differentiation factor 15 (gdf-15) |
| US9862752B2 (en) * | 2013-07-31 | 2018-01-09 | Amgen Inc. | Growth differentiation factor 15 (GDF-15) constructs |
| EP4006049A1 (en) * | 2016-01-29 | 2022-06-01 | Washington University | Gdf15 in glaucoma and methods of use thereof |
| KR102266627B1 (ko) | 2016-03-10 | 2021-06-17 | 엘에스엠트론 주식회사 | 플랫 케이블용 커넥터 |
-
2017
- 2017-08-21 KR KR1020170105714A patent/KR102010652B1/ko active Active
-
2018
- 2018-08-20 JP JP2020501172A patent/JP7053783B2/ja active Active
- 2018-08-20 CN CN201880049717.1A patent/CN111316103B/zh active Active
- 2018-08-20 EP EP18848723.5A patent/EP3674710B1/en active Active
- 2018-08-20 US US16/630,064 patent/US20200292553A1/en not_active Abandoned
- 2018-08-20 WO PCT/KR2018/009548 patent/WO2019039817A2/ko not_active Ceased
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