JP2020526498A5 - - Google Patents
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- Publication number
- JP2020526498A5 JP2020526498A5 JP2019572355A JP2019572355A JP2020526498A5 JP 2020526498 A5 JP2020526498 A5 JP 2020526498A5 JP 2019572355 A JP2019572355 A JP 2019572355A JP 2019572355 A JP2019572355 A JP 2019572355A JP 2020526498 A5 JP2020526498 A5 JP 2020526498A5
- Authority
- JP
- Japan
- Prior art keywords
- pyrazole
- phenyl
- carboxamide
- piperidine
- thiazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 I*1CCNCC1 Chemical compound I*1CCNCC1 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022171152A JP7379639B2 (ja) | 2017-06-29 | 2022-10-26 | キナーゼ阻害剤ならびに作製および使用のための方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762526838P | 2017-06-29 | 2017-06-29 | |
| US62/526,838 | 2017-06-29 | ||
| PCT/US2018/040021 WO2019006126A1 (en) | 2017-06-29 | 2018-06-28 | KINASE INHIBITORS AND METHODS OF MAKING AND USING THEM |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022171152A Division JP7379639B2 (ja) | 2017-06-29 | 2022-10-26 | キナーゼ阻害剤ならびに作製および使用のための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020526498A JP2020526498A (ja) | 2020-08-31 |
| JP2020526498A5 true JP2020526498A5 (https=) | 2021-08-05 |
| JP7167069B2 JP7167069B2 (ja) | 2022-11-08 |
Family
ID=62976284
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019572355A Active JP7167069B2 (ja) | 2017-06-29 | 2018-06-28 | キナーゼ阻害剤ならびに作製および使用のための方法 |
| JP2022171152A Active JP7379639B2 (ja) | 2017-06-29 | 2022-10-26 | キナーゼ阻害剤ならびに作製および使用のための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022171152A Active JP7379639B2 (ja) | 2017-06-29 | 2022-10-26 | キナーゼ阻害剤ならびに作製および使用のための方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US10590121B2 (https=) |
| EP (1) | EP3645525A1 (https=) |
| JP (2) | JP7167069B2 (https=) |
| CN (1) | CN111032642B (https=) |
| CA (1) | CA3068305A1 (https=) |
| WO (1) | WO2019006126A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3068305A1 (en) * | 2017-06-29 | 2019-01-03 | Rigel Pharmaceuticals, Inc. | Kinase inhibitors and methods for making and using |
| JP2022513967A (ja) | 2018-12-20 | 2022-02-09 | アムジエン・インコーポレーテツド | Ｋｉｆ１８ａ阻害剤として有用なヘテロアリールアミド |
| JP7686559B2 (ja) | 2018-12-20 | 2025-06-02 | アムジエン・インコーポレーテツド | Ｋｉｆ１８ａ阻害剤 |
| AU2019401495B2 (en) * | 2018-12-20 | 2025-06-26 | Amgen Inc. | Heteroaryl amides useful as KIF18A inhibitors |
| WO2020182648A1 (en) * | 2019-03-08 | 2020-09-17 | F. Hoffmann-La Roche Ag | Novel imidazole-pyrazole derivatives |
| WO2021018118A1 (en) * | 2019-07-29 | 2021-02-04 | Janssen Pharmaceutica Nv | Compounds and methods for the targeted degradation of interleukin-1 receptor-associated kinase 1 proteins |
| EP4007753B1 (en) | 2019-08-02 | 2025-09-24 | Amgen Inc. | Kif18a inhibitors |
| EP4007638A1 (en) | 2019-08-02 | 2022-06-08 | Amgen Inc. | Pyridine derivatives as kif18a inhibitors |
| KR102851570B1 (ko) * | 2019-08-21 | 2025-09-01 | 더 스크립스 리서치 인스티튜트 | 인터페론 유전자의 자극인자 sting의 모노시클릭 효능제 |
| CN110592056A (zh) * | 2019-09-19 | 2019-12-20 | 昆明理工大学 | 噬菌体裂解酶复合粉剂及其制备方法和应用 |
| CN114981259B (zh) * | 2020-01-22 | 2024-06-18 | 豪夫迈·罗氏有限公司 | 新型杂环化合物 |
| AR121717A1 (es) * | 2020-04-02 | 2022-06-29 | Rigel Pharmaceuticals Inc | Inhibidores de rip1k |
| US20230295146A1 (en) * | 2020-07-24 | 2023-09-21 | The University Of Rochester | Inhibitors of interleukin-1 receptor-associated kinases 1 and 4 |
| JP2024506021A (ja) * | 2021-02-07 | 2024-02-08 | エフ． ホフマン－ラ ロシュ アーゲー | 新規ヘテロアリール置換イミダゾール誘導体 |
| US20240308980A1 (en) * | 2021-03-17 | 2024-09-19 | Merck Sharp & Dohme Llc | Heteroaryl amides as lrrk2 inhibitors, pharmaceutical compositions, and uses thereof |
| WO2023088435A1 (zh) * | 2021-11-19 | 2023-05-25 | 成都奥睿药业有限公司 | 三取代吡啶衍生物的制备及作为芳香烃受体调节物的应用 |
| IL315677A (en) | 2022-03-23 | 2024-11-01 | Rigel Pharmaceuticals Inc | Pyrimid-2-yl-pyrazole compounds as irak inhibitors |
| AU2024214768A1 (en) * | 2023-01-30 | 2025-08-07 | The Johns Hopkins University | 18 f-labeled pet radiotracers for imaging macrophage colony stimulating factor 1 receptor |
| CN118027009B (zh) * | 2024-04-15 | 2024-07-12 | 北京师范大学 | 一类靶向于csf1r激酶的苯基酰胺类化合物及其应用 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5087240A (en) | 1983-08-18 | 1992-02-11 | Drug Delivery Systems Inc. | Transdermal drug patch with conductive fibers |
| US4921475A (en) | 1983-08-18 | 1990-05-01 | Drug Delivery Systems Inc. | Transdermal drug patch with microtubes |
| US4738851A (en) | 1985-09-27 | 1988-04-19 | University Of Iowa Research Foundation, Inc. | Controlled release ophthalmic gel formulation |
| US5163899A (en) | 1987-03-20 | 1992-11-17 | Drug Delivery Systems Inc. | Transdermal drug delivery system |
| US5312325A (en) | 1987-05-28 | 1994-05-17 | Drug Delivery Systems Inc | Pulsating transdermal drug delivery system |
| GB8804164D0 (en) | 1988-02-23 | 1988-03-23 | Tucker J M | Bandage for administering physiologically active compound |
| US4882150A (en) | 1988-06-03 | 1989-11-21 | Kaufman Herbert E | Drug delivery system |
| US5008110A (en) | 1988-11-10 | 1991-04-16 | The Procter & Gamble Company | Storage-stable transdermal patch |
| US5088977A (en) | 1988-12-21 | 1992-02-18 | Drug Delivery Systems Inc. | Electrical transdermal drug applicator with counteractor and method of drug delivery |
| US5521222A (en) | 1989-09-28 | 1996-05-28 | Alcon Laboratories, Inc. | Topical ophthalmic pharmaceutical vehicles |
| DK0431519T3 (da) | 1989-12-04 | 1994-07-04 | Searle & Co | System til transdermal indgivelse af albuterol |
| US5077033A (en) | 1990-08-07 | 1991-12-31 | Mediventures Inc. | Ophthalmic drug delivery with thermo-irreversible gels of polxoxyalkylene polymer and ionic polysaccharide |
| JP2594486B2 (ja) | 1991-01-15 | 1997-03-26 | アルコン ラボラトリーズ インコーポレイテッド | 局所的眼薬組成物 |
| US5352456A (en) | 1991-10-10 | 1994-10-04 | Cygnus Therapeutic Systems | Device for administering drug transdermally which provides an initial pulse of drug |
| DE69228827T2 (de) | 1991-12-18 | 1999-10-21 | Minnesota Mining And Mfg. Co., Saint Paul | Mehrschichtige sperrstrukturen |
| ATE132381T1 (de) | 1992-01-29 | 1996-01-15 | Voelkl Franz Ski | Ballspielschläger, insbesondere tennisschläger |
| IL114193A (en) | 1994-06-20 | 2000-02-29 | Teva Pharma | Ophthalmic pharmaceutical compositions based on sodium alginate |
| ES2094688B1 (es) | 1994-08-08 | 1997-08-01 | Cusi Lab | Manoemulsion del tipo de aceite en agua, util como vehiculo oftalmico y procedimiento para su preparacion. |
| IT1283911B1 (it) | 1996-02-05 | 1998-05-07 | Farmigea Spa | Soluzioni oftalmiche viscosizzate con polisaccaridi della gomma di tamarindo |
| US5800807A (en) | 1997-01-29 | 1998-09-01 | Bausch & Lomb Incorporated | Ophthalmic compositions including glycerin and propylene glycol |
| US6261547B1 (en) | 1998-04-07 | 2001-07-17 | Alcon Manufacturing, Ltd. | Gelling ophthalmic compositions containing xanthan gum |
| US6197934B1 (en) | 1998-05-22 | 2001-03-06 | Collagenesis, Inc. | Compound delivery using rapidly dissolving collagen film |
| CA2890911A1 (en) * | 2013-01-10 | 2014-07-17 | Nimbus Iris, Inc. | Irak inhibitors and uses thereof |
| CA2932353A1 (en) * | 2013-12-13 | 2015-06-18 | Steven P. Treon | Methods to treat lymphoplasmacytic lymphoma |
| LT3286181T (lt) * | 2015-04-22 | 2021-04-26 | Rigel Pharmaceuticals, Inc. | Pirazolo junginiai ir junginių gamybos bei naudojimo būdas |
| JP2018524372A (ja) * | 2015-07-15 | 2018-08-30 | アウリジーン ディスカバリー テクノロジーズ リミテッド | Ｉｒａｋ−４阻害剤としてのインダゾール及びアザインダゾール化合物 |
| DK3331879T3 (da) * | 2015-08-04 | 2020-08-10 | Rigel Pharmaceuticals Inc | Benzazolforbindelser og fremgangsmåder til fremstilling og anvendelse af forbindelserne |
| CA3068305A1 (en) * | 2017-06-29 | 2019-01-03 | Rigel Pharmaceuticals, Inc. | Kinase inhibitors and methods for making and using |
-
2018
- 2018-06-28 CA CA3068305A patent/CA3068305A1/en active Pending
- 2018-06-28 JP JP2019572355A patent/JP7167069B2/ja active Active
- 2018-06-28 EP EP18743281.0A patent/EP3645525A1/en not_active Withdrawn
- 2018-06-28 US US16/022,323 patent/US10590121B2/en active Active
- 2018-06-28 WO PCT/US2018/040021 patent/WO2019006126A1/en not_active Ceased
- 2018-06-28 CN CN201880052620.6A patent/CN111032642B/zh not_active Expired - Fee Related
-
2020
- 2020-02-12 US US16/789,131 patent/US11059814B2/en active Active
-
2021
- 2021-06-08 US US17/341,817 patent/US20210309655A1/en not_active Abandoned
-
2022
- 2022-10-26 JP JP2022171152A patent/JP7379639B2/ja active Active
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