JP2020526214A5 - - Google Patents
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- JP2020526214A5 JP2020526214A5 JP2020501378A JP2020501378A JP2020526214A5 JP 2020526214 A5 JP2020526214 A5 JP 2020526214A5 JP 2020501378 A JP2020501378 A JP 2020501378A JP 2020501378 A JP2020501378 A JP 2020501378A JP 2020526214 A5 JP2020526214 A5 JP 2020526214A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- human
- cells
- mabd
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762530463P | 2017-07-10 | 2017-07-10 | |
| US62/530,463 | 2017-07-10 | ||
| US201762554750P | 2017-09-06 | 2017-09-06 | |
| US62/554,750 | 2017-09-06 | ||
| PCT/EP2018/068537 WO2019011855A1 (en) | 2017-07-10 | 2018-07-09 | ANTIBODIES NEUTRALIZING SIGLEC-9 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020526214A JP2020526214A (ja) | 2020-08-31 |
| JP2020526214A5 true JP2020526214A5 (https=) | 2021-04-30 |
| JP7293188B2 JP7293188B2 (ja) | 2023-06-19 |
Family
ID=62981178
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020501378A Active JP7293188B2 (ja) | 2017-07-10 | 2018-07-09 | Ｓｉｇｌｅｃ－９中和抗体 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US11623954B2 (https=) |
| EP (1) | EP3652208A1 (https=) |
| JP (1) | JP7293188B2 (https=) |
| KR (1) | KR102677225B1 (https=) |
| CN (1) | CN111263769B (https=) |
| AU (1) | AU2018298676A1 (https=) |
| BR (1) | BR112019027365A2 (https=) |
| CA (1) | CA3066514A1 (https=) |
| WO (1) | WO2019011855A1 (https=) |
Families Citing this family (29)
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| US10053513B2 (en) * | 2009-11-30 | 2018-08-21 | Janssen Biotech, Inc. | Antibody Fc mutants with ablated effector functions |
| US9708412B2 (en) | 2015-05-21 | 2017-07-18 | Harpoon Therapeutics, Inc. | Trispecific binding proteins and methods of use |
| US11623958B2 (en) | 2016-05-20 | 2023-04-11 | Harpoon Therapeutics, Inc. | Single chain variable fragment CD3 binding proteins |
| EP3621994A4 (en) | 2017-05-12 | 2020-12-30 | Harpoon Therapeutics, Inc. | MESOTHELIN BINDING PROTEINS |
| US11447545B2 (en) | 2017-07-10 | 2022-09-20 | Innate Pharma | Combination therapy using antibody to human Siglec-9 and antibody to human NKG2A for treating cancer |
| IL315737A (en) | 2017-10-13 | 2024-11-01 | Harpoon Therapeutics Inc | B-cell maturation antigen-binding proteins |
| MX2020003915A (es) | 2017-10-13 | 2020-10-08 | Harpoon Therapeutics Inc | Proteinas trispecificas y metodos de uso. |
| US12195544B2 (en) | 2018-09-21 | 2025-01-14 | Harpoon Therapeutics, Inc. | EGFR binding proteins and methods of use |
| US10815311B2 (en) | 2018-09-25 | 2020-10-27 | Harpoon Therapeutics, Inc. | DLL3 binding proteins and methods of use |
| EP3980462A4 (en) * | 2019-06-04 | 2023-09-20 | Verseau Therapeutics, Inc. | ANTI-SIGLEC-9 COMPOSITIONS AND METHODS OF MODULATING INFLAMMATORY PHENOTYPES OF MYELOID CELLS AND RELATED USES |
| WO2021024020A1 (en) | 2019-08-06 | 2021-02-11 | Astellas Pharma Inc. | Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer |
| WO2021091885A2 (en) | 2019-11-04 | 2021-05-14 | Alector Llc | Siglec-9 ecd fusion molecules and methods of use thereof |
| KR20220101126A (ko) * | 2019-11-14 | 2022-07-19 | 메모 테라퓨틱스 아게 | 항-Siglec-9 항체 분자 |
| KR20230035576A (ko) | 2020-07-07 | 2023-03-14 | 비온테크 에스이 | Hpv 양성 암 치료용 rna |
| TW202245808A (zh) | 2020-12-21 | 2022-12-01 | 德商拜恩迪克公司 | 用於治療癌症之治療性ｒｎａ |
| WO2022135667A1 (en) | 2020-12-21 | 2022-06-30 | BioNTech SE | Therapeutic rna for treating cancer |
| WO2022135666A1 (en) | 2020-12-21 | 2022-06-30 | BioNTech SE | Treatment schedule for cytokine proteins |
| MX2023008029A (es) * | 2021-01-06 | 2023-08-25 | Palleon Pharmaceuticals Inc | Proteinas de fusion de anticuerpo y sialidasa-pd-1 y metodos para utilizarlas. |
| EP4320164A4 (en) * | 2021-04-05 | 2025-07-16 | Naya Biosciences Inc | BISPECIFIC ANTIBODIES TARGETING NKP46 AND CD38 AND METHODS OF USE THEREOF |
| CA3225254A1 (en) | 2021-07-13 | 2023-01-19 | BioNTech SE | Multispecific binding agents against cd40 and cd137 in combination therapy for cancer |
| TW202333802A (zh) | 2021-10-11 | 2023-09-01 | 德商拜恩迪克公司 | 用於肺癌之治療性rna(二) |
| CN117447592B (zh) * | 2022-07-26 | 2024-05-28 | 北京东方百泰生物科技股份有限公司 | 一种抗Siglec-15单克隆抗体、其抗原结合片段及其应用 |
| JP2026501506A (ja) | 2022-12-14 | 2026-01-16 | アステラス・ファーマ・ヨーロッパ・ベスローデン・フェンノートシャップ | Ｃｌｄｎ１８．２及びｃｄ３に結合する二重特異性結合剤並びに免疫チェックポイント阻害剤を含む併用療法 |
| CN120361243A (zh) * | 2023-08-18 | 2025-07-25 | 上海美雅珂生物技术有限责任公司 | 5t4抗体药物偶联物及其应用 |
| TW202541837A (zh) | 2023-12-08 | 2025-11-01 | 日商安斯泰來製藥公司 | 含有結合至cldn18.2和cd3之雙特異性結合劑和穩定或增加cldn18.2表現之藥劑之組合療法 |
| WO2026033885A1 (en) | 2024-08-08 | 2026-02-12 | Astellas Pharma Inc. | Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2 |
| WO2025120866A1 (en) | 2023-12-08 | 2025-06-12 | Astellas Pharma Inc. | Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2 |
| WO2025120867A1 (en) | 2023-12-08 | 2025-06-12 | Astellas Pharma Inc. | Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and anti-vegfr2 antibodies |
| US20260022170A1 (en) * | 2024-05-10 | 2026-01-22 | Adaptam Therapeutics S.L | Anti-siglec-9 antibodies and uses thereof |
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| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5567610A (en) | 1986-09-04 | 1996-10-22 | Bioinvent International Ab | Method of producing human monoclonal antibodies and kit therefor |
| US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US6673986B1 (en) | 1990-01-12 | 2004-01-06 | Abgenix, Inc. | Generation of xenogeneic antibodies |
| US5229275A (en) | 1990-04-26 | 1993-07-20 | Akzo N.V. | In-vitro method for producing antigen-specific human monoclonal antibodies |
| US5776427A (en) | 1992-03-05 | 1998-07-07 | Board Of Regents, The University Of Texas System | Methods for targeting the vasculature of solid tumors |
| US6737056B1 (en) | 1999-01-15 | 2004-05-18 | Genentech, Inc. | Polypeptide variants with altered effector function |
| IT1307826B1 (it) | 1999-12-16 | 2001-11-19 | Dipartimento Di Medicina Speri | Metodo diagnostico per il riconoscimento di cellule mieloidi normali eleucemiche, ligandi utilizzati in detto metodo e formulazioni ad uso |
| ATE483472T1 (de) | 2002-05-30 | 2010-10-15 | Macrogenics Inc | Cd16a bindungsproteine und verwendung zur behandlung von immunkrankheiten |
| DK2439273T3 (da) | 2005-05-09 | 2019-06-03 | Ono Pharmaceutical Co | Humane monoklonale antistoffer til programmeret død-1(pd-1) og fremgangsmåder til behandling af cancer ved anvendelse af anti-pd-1- antistoffer alene eller i kombination med andre immunterapeutika |
| PT1907424E (pt) | 2005-07-01 | 2015-10-09 | Squibb & Sons Llc | Anticorpos monoclonais humanos para o ligando 1 de morte programada (pd-l1) |
| GB0521991D0 (en) * | 2005-10-28 | 2005-12-07 | Univ Dundee | Siglec-9 binding agents |
| BR122017025062B8 (pt) | 2007-06-18 | 2021-07-27 | Merck Sharp & Dohme | anticorpo monoclonal ou fragmento de anticorpo para o receptor de morte programada humano pd-1, polinucleotídeo e composição compreendendo o referido anticorpo ou fragmento |
| WO2009014708A2 (en) | 2007-07-23 | 2009-01-29 | Cell Genesys, Inc. | Pd-1 antibodies in combination with a cytokine-secreting cell and methods of use thereof |
| CN101970499B (zh) | 2008-02-11 | 2014-12-31 | 治疗科技公司 | 用于肿瘤治疗的单克隆抗体 |
| EP2262837A4 (en) | 2008-03-12 | 2011-04-06 | Merck Sharp & Dohme | PD-1 BINDING PROTEINS |
| EP3255060A1 (en) | 2008-12-09 | 2017-12-13 | F. Hoffmann-La Roche AG | Anti-pd-l1 antibodies and their use to enhance t-cell function |
| PL2504364T3 (pl) | 2009-11-24 | 2017-12-29 | Medimmune Limited | Ukierunkowane środki wiążące przeciwko B7-H1 |
| US8961967B2 (en) | 2009-11-30 | 2015-02-24 | Janssen Biotech, Inc. | Antibody Fc mutants with ablated effector functions |
| AR083847A1 (es) | 2010-11-15 | 2013-03-27 | Novartis Ag | Variantes de fc (fragmento constante) silenciosas de los anticuerpos anti-cd40 |
| JP6072771B2 (ja) | 2011-04-20 | 2017-02-01 | メディミューン，エルエルシー | Ｂ７−ｈ１およびｐｄ−１に結合する抗体およびその他の分子 |
| MX368257B (es) | 2011-08-01 | 2019-09-26 | Genentech Inc | Antagonistas de unión al eje pd-1e inhibidores de mek y sus usos en el tratamiento de cáncer. |
| SG11201400916XA (en) | 2011-08-22 | 2014-06-27 | Cangene Corp | Clostridium difficile antibodies |
| SG10201804945WA (en) | 2013-12-12 | 2018-07-30 | Shanghai hengrui pharmaceutical co ltd | Pd-1 antibody, antigen-binding fragment thereof, and medical application thereof |
| KR102345173B1 (ko) | 2014-03-14 | 2021-12-29 | 이나뜨 파르마 에스.에이. | 증가된 안정성을 가진 인간화 항체 |
| WO2016038064A1 (en) | 2014-09-10 | 2016-03-17 | Innate Pharma | Cross reactive siglec antibodies |
| TWI688575B (zh) | 2014-09-11 | 2020-03-21 | 日商塩野義製藥股份有限公司 | 阻礙血管內皮脂酶之酵素活性的人類化單株抗體 |
| CA3003458A1 (en) * | 2015-10-29 | 2017-05-04 | Alector Llc | Anti-siglec-9 antibodies and methods of use thereof |
| CA3004972A1 (en) | 2015-11-17 | 2017-05-26 | Innate Pharma | Siglec-10 antibodies |
| EP3426688A1 (en) * | 2016-03-08 | 2019-01-16 | Innate Pharma | Siglec neutralizing antibodies |
| US11447545B2 (en) | 2017-07-10 | 2022-09-20 | Innate Pharma | Combination therapy using antibody to human Siglec-9 and antibody to human NKG2A for treating cancer |
-
2018
- 2018-07-09 AU AU2018298676A patent/AU2018298676A1/en not_active Abandoned
- 2018-07-09 WO PCT/EP2018/068537 patent/WO2019011855A1/en not_active Ceased
- 2018-07-09 EP EP18743425.3A patent/EP3652208A1/en not_active Withdrawn
- 2018-07-09 KR KR1020207001755A patent/KR102677225B1/ko active Active
- 2018-07-09 BR BR112019027365-4A patent/BR112019027365A2/pt unknown
- 2018-07-09 CN CN201880046134.3A patent/CN111263769B/zh active Active
- 2018-07-09 CA CA3066514A patent/CA3066514A1/en active Pending
- 2018-07-09 US US16/629,588 patent/US11623954B2/en active Active
- 2018-07-09 JP JP2020501378A patent/JP7293188B2/ja active Active