JP2020525467A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020525467A5 JP2020525467A5 JP2019571938A JP2019571938A JP2020525467A5 JP 2020525467 A5 JP2020525467 A5 JP 2020525467A5 JP 2019571938 A JP2019571938 A JP 2019571938A JP 2019571938 A JP2019571938 A JP 2019571938A JP 2020525467 A5 JP2020525467 A5 JP 2020525467A5
- Authority
- JP
- Japan
- Prior art keywords
- nanoparticles
- suspension
- tumor
- nanoparticles according
- ionizing radiation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002105 nanoparticle Substances 0.000 claims 28
- 239000000725 suspension Substances 0.000 claims 19
- 206010028980 Neoplasm Diseases 0.000 claims 13
- 230000005865 ionizing radiation Effects 0.000 claims 9
- 210000004027 cell Anatomy 0.000 claims 7
- 230000000694 effects Effects 0.000 claims 5
- 102000004080 NADPH Oxidase 5 Human genes 0.000 claims 4
- 108010082695 NADPH Oxidase 5 Proteins 0.000 claims 4
- 101000669917 Homo sapiens Rho-associated protein kinase 1 Proteins 0.000 claims 3
- 102100039313 Rho-associated protein kinase 1 Human genes 0.000 claims 3
- 239000013522 chelant Substances 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 210000004881 tumor cell Anatomy 0.000 claims 3
- 230000002301 combined effect Effects 0.000 claims 2
- 239000002955 immunomodulating agent Substances 0.000 claims 2
- 239000012275 CTLA-4 inhibitor Substances 0.000 claims 1
- 229940045513 CTLA4 antagonist Drugs 0.000 claims 1
- 101001117317 Homo sapiens Programmed cell death 1 ligand 1 Proteins 0.000 claims 1
- 229940076838 Immune checkpoint inhibitor Drugs 0.000 claims 1
- 102000037984 Inhibitory immune checkpoint proteins Human genes 0.000 claims 1
- 108091008026 Inhibitory immune checkpoint proteins Proteins 0.000 claims 1
- 102100024216 Programmed cell death 1 ligand 1 Human genes 0.000 claims 1
- 230000032683 aging Effects 0.000 claims 1
- 230000006907 apoptotic process Effects 0.000 claims 1
- 230000000973 chemotherapeutic effect Effects 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 239000012274 immune-checkpoint protein inhibitor Substances 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 230000001404 mediated effect Effects 0.000 claims 1
- 229910052761 rare earth metal Inorganic materials 0.000 claims 1
- 150000002910 rare earth metals Chemical class 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17305869.4 | 2017-07-05 | ||
| EP17305869.4A EP3424533A1 (en) | 2017-07-05 | 2017-07-05 | Methods for treating tumors |
| PCT/EP2018/068099 WO2019008040A1 (en) | 2017-07-05 | 2018-07-04 | METHODS OF TREATING TUMORS |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020525467A JP2020525467A (ja) | 2020-08-27 |
| JP2020525467A5 true JP2020525467A5 (enExample) | 2021-08-12 |
| JP7386711B2 JP7386711B2 (ja) | 2023-11-27 |
Family
ID=59363059
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019571938A Active JP7386711B2 (ja) | 2017-07-05 | 2018-07-04 | 腫瘍を治療するための方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20210128730A1 (enExample) |
| EP (2) | EP3424533A1 (enExample) |
| JP (1) | JP7386711B2 (enExample) |
| KR (1) | KR102799910B1 (enExample) |
| CN (1) | CN110913909A (enExample) |
| AU (1) | AU2018296426B2 (enExample) |
| CA (1) | CA3068355A1 (enExample) |
| TW (1) | TWI796340B (enExample) |
| WO (1) | WO2019008040A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2959502B1 (fr) | 2010-04-30 | 2012-09-07 | Nanoh | Nanoparticules ultrafines a matrice polyorganosiloxane fonctionnalisee et incluant des complexes metalliques ; leur procede d'obtention et leurs applications en imagerie medicale et/ou therapie |
| CA3148734A1 (en) | 2019-07-29 | 2021-02-04 | Nh Theraguix | High-z-element containing nanoparticles for use in the treatement of tumors |
| FR3099883A1 (fr) | 2019-08-14 | 2021-02-19 | Nh Theraguix | Nanoparticules pour le traitement du cancer par rayonnement de radiofréquence |
| TWI833803B (zh) * | 2019-09-12 | 2024-03-01 | 法商Ｎｈ蕾哈吉公司 | 含有高ｚ元素之奈米顆粒在製備用於治療腫瘤之藥物之用途 |
| EP3795178A1 (en) | 2019-09-19 | 2021-03-24 | Nh Theraguix | Methods for triggering m1 macrophage polarization |
| EP4096781A1 (en) | 2020-01-28 | 2022-12-07 | RefleXion Medical, Inc. | Joint optimization of radionuclide and external beam radiotherapy |
| AU2021270780A1 (en) | 2020-05-15 | 2022-11-24 | Centre Georges-François Leclerc | Methods for image-guided radiotherapy |
| CA3084780A1 (en) * | 2020-06-24 | 2021-12-24 | Rodney HERRING | Use of low iron oxide iron-doped titanium dioxide nanoparticles in the treatment of tumors and other diseases |
| FR3116216B1 (fr) | 2020-11-19 | 2023-10-27 | Nh Theraguix | Procédé de préparation de nanoparticules |
| FR3116197A1 (fr) * | 2020-11-19 | 2022-05-20 | Nh Theraguix | Procédé de traitement de tumeurs par captation du cuivre et/ou du fer |
| CN120359049A (zh) | 2022-07-13 | 2025-07-22 | 蒙彼利埃大学 | 纳米颗粒和放射性药物的联合疗法 |
| WO2024058504A1 (ko) * | 2022-09-16 | 2024-03-21 | (주)한국원자력 엔지니어링 | 앱스코팔 효과를 갖는, 암의 예방 또는 치료용 조성물 및 이를 이용한 암의 예방 또는 치료방법 |
| EP4605019A2 (en) | 2022-10-18 | 2025-08-27 | Nh Theraguix | Methods for imaging using spcct |
| WO2024236048A1 (en) | 2023-05-16 | 2024-11-21 | Nh Theraguix | Combination therapy for treating tumors with radiotherapy |
| FR3151755A1 (fr) | 2023-07-31 | 2025-02-07 | Nh Theraguix | Procédé de quantification de la concentration d’un agent de contraste et dispositif associé |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004509967A (ja) | 2000-09-25 | 2004-04-02 | ザ、プロクター、エンド、ギャンブル、カンパニー | 医学及び治療法の適用に使用するための金属錯体 |
| FR2867180B1 (fr) | 2004-03-02 | 2006-06-16 | Univ Claude Bernard Lyon | Nanoparticules hybrides comprenant un coeur de ln203 porteuses de ligands biologiques et leur procede de preparation |
| US20060084666A1 (en) * | 2004-10-18 | 2006-04-20 | Harari Paul M | Combined treatment with radiation and an epidermal growth factor receptor kinase inhibitor |
| GB0704932D0 (en) * | 2007-03-14 | 2007-04-25 | Astex Therapeutics Ltd | Pharmaceutical compounds |
| FR2922106B1 (fr) | 2007-10-16 | 2011-07-01 | Univ Claude Bernard Lyon | Utilisation de nanoparticules a base de lanthanides comme agents radiosensibilisants. |
| FR2959502B1 (fr) | 2010-04-30 | 2012-09-07 | Nanoh | Nanoparticules ultrafines a matrice polyorganosiloxane fonctionnalisee et incluant des complexes metalliques ; leur procede d'obtention et leurs applications en imagerie medicale et/ou therapie |
| WO2013185032A1 (en) * | 2012-06-07 | 2013-12-12 | President And Fellows Of Harvard College | Nanotherapeutics for drug targeting |
| DK2867368T3 (da) * | 2012-07-06 | 2022-01-31 | Roussy Inst Gustave | Samtidig detektering af kannibalisme og senescens som prognostisk markør for cancer |
| UA116007C2 (uk) * | 2013-01-25 | 2018-01-25 | Нанобіотікс | Композиції неорганічних наночастинок у комбінації з іонізуючим випромінюванням для лікування раку |
| KR101662755B1 (ko) * | 2015-04-28 | 2016-10-05 | 한국생명공학연구원 | Nox5의 발현 또는 활성을 억제하는 제제를 포함하는 암 치료용 조성물 |
| US11096962B2 (en) * | 2015-05-28 | 2021-08-24 | Nanobiotix | Nanoparticles for use as a therapeutic vaccine |
| US20160354333A1 (en) * | 2015-06-03 | 2016-12-08 | UND Life Sciences, LLC | Compositions of polyunsaturated fatty acids and methods of use thereof |
-
2017
- 2017-07-05 EP EP17305869.4A patent/EP3424533A1/en not_active Withdrawn
-
2018
- 2018-07-04 CA CA3068355A patent/CA3068355A1/en active Pending
- 2018-07-04 US US16/628,611 patent/US20210128730A1/en not_active Abandoned
- 2018-07-04 CN CN201880044783.XA patent/CN110913909A/zh active Pending
- 2018-07-04 KR KR1020207003481A patent/KR102799910B1/ko active Active
- 2018-07-04 JP JP2019571938A patent/JP7386711B2/ja active Active
- 2018-07-04 TW TW107123130A patent/TWI796340B/zh not_active IP Right Cessation
- 2018-07-04 EP EP18734576.4A patent/EP3648793A1/en not_active Withdrawn
- 2018-07-04 AU AU2018296426A patent/AU2018296426B2/en not_active Ceased
- 2018-07-04 WO PCT/EP2018/068099 patent/WO2019008040A1/en not_active Ceased
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Hayward et al. | Exercise training mitigates anthracycline‐induced chronic cardiotoxicity in a juvenile rat model | |
| Ebert et al. | Eliminating hepatitis B by antagonizing cellular inhibitors of apoptosis | |
| Lin et al. | Comparing gold nano-particle enhanced radiotherapy with protons, megavoltage photons and kilovoltage photons: a Monte Carlo simulation | |
| Seidensticker et al. | Prospective randomized trial of enoxaparin, pentoxifylline and ursodeoxycholic acid for prevention of radiation-induced liver toxicity | |
| Kirkby et al. | Targeting mitochondria in cancer cells using gold nanoparticle‐enhanced radiotherapy: A Monte Carlo study | |
| Takino et al. | Analysis of the effect of chronic and low-dose radiation exposure on spermatogenic cells of male large Japanese field mice (Apodemus speciosus) after the Fukushima Daiichi nuclear power plant accident | |
| JP6754846B2 (ja) | βアミロイド沈着プラークを除去するための中性子捕捉治療システム | |
| JP2018502120A5 (enExample) | ||
| JP2019532047A5 (enExample) | ||
| Sollazzo et al. | Interaction of low and high LET radiation in TK6 cells—mechanistic aspects and significance for radiation protection | |
| Sweet et al. | Neurogenic effects of low-dose whole-body HZE (Fe) ion and gamma irradiation | |
| Morimoto et al. | Radiation dose and gene expression analysis of wild boar 10 years after the Fukushima Daiichi Nuclear Plant accident | |
| Sezen et al. | Pulsed radiotherapy to mitigate high tumor burden and generate immune memory | |
| Melzig et al. | Combined external beam radiotherapy with carbon ions and tumor targeting endoradiotherapy | |
| MX2022006381A (es) | Metodo para generar celulas inmunoreguladoras en una muestra derivada de sangre. | |
| JP2020044286A5 (enExample) | ||
| Rump et al. | The impact of time on decorporation efficacy after a “dirty bomb” attack studied by simulation | |
| Kerr et al. | Effects of clinically relevant radionuclides on the activation of a type I interferon response by radiopharmaceuticals in syngeneic murine tumor models | |
| Krebs et al. | The estimation of the nonrecuperable injury caused by ionizing radiation | |
| Tian et al. | Expression of genes involved in mouse lung cell differentiation/regulation after acute exposure to photons and protons with or without low-dose preirradiation | |
| Chachin et al. | Respiratory metabolism and potassium release of irradiated potatoes | |
| Beňová et al. | THE ELIMINATION OF THE NEGATIVE EFFECTS OF CADMIUM IN Artemia franciscana BY EXPOSURE TO IONIZING RADIATION | |
| JP2016512221A5 (enExample) | ||
| Soeda et al. | PLX-R18-Placenta-derived Mesenchymal-like Stromal Cells are efficacious in reducing lethality in Gastrointestinal Acute Radiation Syndrome (GI-ARS) Mouse Model | |
| Stavreva et al. | On the possibility of estimating the radiosensitivity range in a cell mixture |