JP2020524694A - がんの処置における使用のためのIL−1β結合性抗体 - Google Patents

がんの処置における使用のためのIL−1β結合性抗体 Download PDF

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JP2020524694A
JP2020524694A JP2019570897A JP2019570897A JP2020524694A JP 2020524694 A JP2020524694 A JP 2020524694A JP 2019570897 A JP2019570897 A JP 2019570897A JP 2019570897 A JP2019570897 A JP 2019570897A JP 2020524694 A JP2020524694 A JP 2020524694A
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cancer
use according
functional fragment
canakinumab
patient
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JP2020524694A5 (enExample
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リゲロス−セイラン,モニカ
マチャバ,パトリス
トゥレン,トム
リドカー,ポール
リビー,ピーター
オトウェル,ペネロペ
ヤン ラウ,イー
ヤン ラウ,イー
ドゥガン,マーガレット
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ノバルティス アーゲー
ノバルティス アーゲー
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • C07K16/245IL-1
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/282Platinum compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001136Cytokines
    • A61K39/00114Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57423Specifically defined cancers of lung
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/80Vaccine for a specifically defined cancer
    • A61K2039/82Colon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/80Vaccine for a specifically defined cancer
    • A61K2039/828Stomach
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/80Vaccine for a specifically defined cancer
    • A61K2039/836Intestine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/80Vaccine for a specifically defined cancer
    • A61K2039/86Lung
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/80Vaccine for a specifically defined cancer
    • A61K2039/868Vaccine for a specifically defined cancer kidney
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Analytical Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Dermatology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
JP2019570897A 2017-06-22 2018-05-03 がんの処置における使用のためのIL−1β結合性抗体 Withdrawn JP2020524694A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022146790A JP2022181214A (ja) 2017-06-22 2022-09-15 がんの処置における使用のためのIL-1β結合性抗体

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US201762523458P 2017-06-22 2017-06-22
US62/523,458 2017-06-22
US201762529515P 2017-07-07 2017-07-07
US62/529,515 2017-07-07
US201762550325P 2017-08-25 2017-08-25
US201762550307P 2017-08-25 2017-08-25
US62/550,325 2017-08-25
US62/550,307 2017-08-25
US201762596054P 2017-12-07 2017-12-07
US62/596,054 2017-12-07
US201862649631P 2018-03-29 2018-03-29
US62/649,631 2018-03-29
PCT/IB2018/053096 WO2018234879A1 (en) 2017-06-22 2018-05-03 Il-1beta binding antibodies for use in treating cancer

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JP2020524694A5 JP2020524694A5 (enExample) 2021-06-17

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JP2019570897A Withdrawn JP2020524694A (ja) 2017-06-22 2018-05-03 がんの処置における使用のためのIL−1β結合性抗体
JP2019571038A Withdrawn JP2020524698A (ja) 2017-06-22 2018-06-22 がんの処置における使用のためのIL−1β結合性抗体
JP2022146790A Pending JP2022181214A (ja) 2017-06-22 2022-09-15 がんの処置における使用のためのIL-1β結合性抗体
JP2023014125A Withdrawn JP2023071657A (ja) 2017-06-22 2023-02-01 がんの処置における使用のためのIL-1β結合性抗体

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JP2019571038A Withdrawn JP2020524698A (ja) 2017-06-22 2018-06-22 がんの処置における使用のためのIL−1β結合性抗体
JP2022146790A Pending JP2022181214A (ja) 2017-06-22 2022-09-15 がんの処置における使用のためのIL-1β結合性抗体
JP2023014125A Withdrawn JP2023071657A (ja) 2017-06-22 2023-02-01 がんの処置における使用のためのIL-1β結合性抗体

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US (3) US20190048072A1 (enExample)
EP (1) EP3642234A1 (enExample)
JP (4) JP2020524694A (enExample)
KR (2) KR20200019865A (enExample)
CN (1) CN110831967A (enExample)
AU (4) AU2018287519B2 (enExample)
BR (1) BR112019027558A2 (enExample)
CA (2) CA3061874A1 (enExample)
CL (1) CL2019003799A1 (enExample)
CO (1) CO2019014433A2 (enExample)
IL (1) IL271221A (enExample)
JO (1) JOP20190292A1 (enExample)
MX (1) MX2019015516A (enExample)
PH (1) PH12019502857A1 (enExample)
RU (1) RU2020102237A (enExample)
SG (1) SG11201911283UA (enExample)
TW (3) TW201904993A (enExample)
WO (1) WO2018234879A1 (enExample)

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