JP2020521117A5 - - Google Patents
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- JP2020521117A5 JP2020521117A5 JP2019560086A JP2019560086A JP2020521117A5 JP 2020521117 A5 JP2020521117 A5 JP 2020521117A5 JP 2019560086 A JP2019560086 A JP 2019560086A JP 2019560086 A JP2019560086 A JP 2019560086A JP 2020521117 A5 JP2020521117 A5 JP 2020521117A5
- Authority
- JP
- Japan
- Prior art keywords
- age
- patient
- cells
- sample
- cell surface
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004027 cell Anatomy 0.000 claims 34
- 239000000523 sample Substances 0.000 claims 15
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 14
- 238000000034 method Methods 0.000 claims 10
- 201000010099 disease Diseases 0.000 claims 7
- 230000001413 cellular effect Effects 0.000 claims 6
- 208000035475 disorder Diseases 0.000 claims 6
- 230000001575 pathological effect Effects 0.000 claims 6
- 239000000463 material Substances 0.000 claims 5
- 125000003275 alpha amino acid group Chemical group 0.000 claims 4
- 230000032677 cell aging Effects 0.000 claims 4
- 230000008049 biological aging Effects 0.000 claims 3
- 230000010094 cellular senescence Effects 0.000 claims 3
- 230000032683 aging Effects 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229940124597 therapeutic agent Drugs 0.000 claims 2
- 108010005094 Advanced Glycation End Products Proteins 0.000 claims 1
- 210000001744 T-lymphocyte Anatomy 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000013068 control sample Substances 0.000 claims 1
- 230000000779 depleting effect Effects 0.000 claims 1
- 210000002919 epithelial cell Anatomy 0.000 claims 1
- 210000003743 erythrocyte Anatomy 0.000 claims 1
- 210000002950 fibroblast Anatomy 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 210000003296 saliva Anatomy 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023064753A JP2023098996A (ja) | 2017-05-04 | 2023-04-12 | 診断用終末糖化産物抗体 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762501424P | 2017-05-04 | 2017-05-04 | |
| US62/501,424 | 2017-05-04 | ||
| US201762610003P | 2017-12-22 | 2017-12-22 | |
| US62/610,003 | 2017-12-22 | ||
| PCT/US2018/030931 WO2018204679A1 (en) | 2017-05-04 | 2018-05-03 | Diagnostic advanced glycation end-product antibodies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023064753A Division JP2023098996A (ja) | 2017-05-04 | 2023-04-12 | 診断用終末糖化産物抗体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020521117A JP2020521117A (ja) | 2020-07-16 |
| JP2020521117A5 true JP2020521117A5 (enExample) | 2021-06-17 |
Family
ID=62223287
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019560086A Pending JP2020521117A (ja) | 2017-05-04 | 2018-05-03 | 診断用終末糖化産物抗体 |
| JP2023064753A Pending JP2023098996A (ja) | 2017-05-04 | 2023-04-12 | 診断用終末糖化産物抗体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023064753A Pending JP2023098996A (ja) | 2017-05-04 | 2023-04-12 | 診断用終末糖化産物抗体 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20200150131A1 (enExample) |
| EP (1) | EP3619540A1 (enExample) |
| JP (2) | JP2020521117A (enExample) |
| KR (2) | KR20200003067A (enExample) |
| CN (1) | CN110832327A (enExample) |
| AU (1) | AU2018261622A1 (enExample) |
| CA (1) | CA3062082A1 (enExample) |
| IL (1) | IL270285B2 (enExample) |
| WO (1) | WO2018204679A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0913047A2 (pt) | 2008-05-23 | 2013-03-05 | Siwa Corp | anticorpo monoclonal humanizado, seu uso, bem como aparelho e mÉtodo in vitro para promover processos regenerativos em uma cultura de tecido ou cultura de cÉlula |
| US8721571B2 (en) | 2010-11-22 | 2014-05-13 | Siwa Corporation | Selective removal of cells having accumulated agents |
| IL251210B2 (en) | 2014-09-19 | 2023-12-01 | Siwa Corp | Anti-aging antibodies for the treatment of inflammation and autoimmune disorders |
| US9993535B2 (en) | 2014-12-18 | 2018-06-12 | Siwa Corporation | Method and composition for treating sarcopenia |
| US10358502B2 (en) | 2014-12-18 | 2019-07-23 | Siwa Corporation | Product and method for treating sarcopenia |
| PL3337829T3 (pl) | 2016-02-19 | 2020-05-18 | Siwa Corporation | Sposób i kompozycja do leczenia raka, zwalczania przerzutowych komórek nowotworowych i zapobiegania przerzutom nowotworowym przy użyciu przeciwciała przeciwko produktom końcowych zaawansowanej glikacji (AGE) |
| AU2017250301A1 (en) | 2016-04-15 | 2018-11-15 | Siwa Corporation | Anti-age antibodies for treating neurodegenerative disorders |
| JP2019518763A (ja) | 2016-06-23 | 2019-07-04 | シワ コーポレーション | 様々な疾患及び障害の治療において使用するためのワクチン |
| US10995151B1 (en) | 2017-01-06 | 2021-05-04 | Siwa Corporation | Methods and compositions for treating disease-related cachexia |
| US10961321B1 (en) | 2017-01-06 | 2021-03-30 | Siwa Corporation | Methods and compositions for treating pain associated with inflammation |
| US10925937B1 (en) | 2017-01-06 | 2021-02-23 | Siwa Corporation | Vaccines for use in treating juvenile disorders associated with inflammation |
| US10858449B1 (en) | 2017-01-06 | 2020-12-08 | Siwa Corporation | Methods and compositions for treating osteoarthritis |
| EP3609923A1 (en) | 2017-04-13 | 2020-02-19 | Siwa Corporation | Humanized monoclonal advanced glycation end-product antibody |
| US11518801B1 (en) | 2017-12-22 | 2022-12-06 | Siwa Corporation | Methods and compositions for treating diabetes and diabetic complications |
| WO2020023532A1 (en) * | 2018-07-23 | 2020-01-30 | Siwa Corporation | Methods and compositions for treating chronic effects of radiation and chemical exposure |
| WO2021113152A1 (en) * | 2019-12-02 | 2021-06-10 | Viome, Inc. | Detection and elimination of aberrant cells |
| KR20210101481A (ko) * | 2020-02-10 | 2021-08-19 | 한국과학기술연구원 | 초음파 출력부를 포함하는 노화세포 제거 장치 |
| CA3177449A1 (en) | 2020-05-01 | 2021-11-04 | Lewis S. Gruber | Methods of treating infections |
| US20240000930A1 (en) | 2020-12-09 | 2024-01-04 | Siwa Corporation | Methods and compositions for treating kidney diseases |
| JP7607149B2 (ja) * | 2021-04-09 | 2024-12-26 | カチョン ユニバーシティ オブ インダストリー－アカデミック コーオペレイション ファウンデイション | グリコトキシン、グリコトキシンに結合した特定タンパク質、またはグリコトキシン－特定タンパク質複合体を含む神経変性疾患のバイオマーカー |
| CA3229602A1 (en) | 2021-08-20 | 2023-02-23 | Siwa Corporation | Methods and compositions for treating fibrotic diseases |
| CN114624362A (zh) * | 2022-03-17 | 2022-06-14 | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | 一种检测血清中晚期糖基化终末产物的试剂盒及其应用 |
| CN118562721A (zh) * | 2024-06-27 | 2024-08-30 | 广州市华代生物科技有限公司 | 一种基于全皮模型的糖化衰老模型及抗糖效果测试评价方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5624804A (en) * | 1991-12-20 | 1997-04-29 | The Rockefeller University | Immunochemical detection of In vivo advanced glycosylation end products |
| US6380165B1 (en) | 1997-09-19 | 2002-04-30 | The Picower Institute For Medical Research | Immunological advanced glycation endproduct crosslink |
| JP4012722B2 (ja) * | 2001-11-22 | 2007-11-21 | 株式会社トランスジェニック | カルボキシメチル化ペプチドに対する抗体 |
| WO2009085216A2 (en) | 2007-12-20 | 2009-07-09 | Squicor | Compositions and methods for detecting or elimninating senescent cells to diagnose or treat disease |
| BRPI0913047A2 (pt) | 2008-05-23 | 2013-03-05 | Siwa Corp | anticorpo monoclonal humanizado, seu uso, bem como aparelho e mÉtodo in vitro para promover processos regenerativos em uma cultura de tecido ou cultura de cÉlula |
| WO2010005531A2 (en) * | 2008-06-30 | 2010-01-14 | The Johns Hopkins University | Methods for the detection of advanced glycation endproducts and markers for disease |
| JP5808801B2 (ja) * | 2010-06-18 | 2015-11-10 | ディアフノプティクス ホールディング ベー．フェー． | 皮膚組織の自己蛍光値を求めるための方法および装置 |
| WO2012047629A2 (en) * | 2010-09-27 | 2012-04-12 | Siwa Corporation | Selective removal of age-modified cells for treatment of ather0sclerosis |
| EP3099380B1 (en) * | 2014-01-28 | 2021-08-11 | Buck Institute for Research on Aging | Methods and compositions for killing senescent cells and for treating senescence-associated diseases and disorders |
| JP2017527580A (ja) * | 2014-09-12 | 2017-09-21 | ザ プロクター アンド ギャンブル カンパニー | 老化防止スキンケア組成物及びレジメン |
| US10358502B2 (en) * | 2014-12-18 | 2019-07-23 | Siwa Corporation | Product and method for treating sarcopenia |
| MA42979A (fr) * | 2015-10-13 | 2021-05-26 | Siwa Corp | Anticorps anti-age et procédés d'utilisation correspondants |
| PL3337829T3 (pl) | 2016-02-19 | 2020-05-18 | Siwa Corporation | Sposób i kompozycja do leczenia raka, zwalczania przerzutowych komórek nowotworowych i zapobiegania przerzutom nowotworowym przy użyciu przeciwciała przeciwko produktom końcowych zaawansowanej glikacji (AGE) |
-
2018
- 2018-05-03 AU AU2018261622A patent/AU2018261622A1/en not_active Abandoned
- 2018-05-03 KR KR1020197035140A patent/KR20200003067A/ko not_active Ceased
- 2018-05-03 EP EP18726656.4A patent/EP3619540A1/en not_active Withdrawn
- 2018-05-03 JP JP2019560086A patent/JP2020521117A/ja active Pending
- 2018-05-03 WO PCT/US2018/030931 patent/WO2018204679A1/en not_active Ceased
- 2018-05-03 US US16/610,473 patent/US20200150131A1/en not_active Abandoned
- 2018-05-03 CN CN201880044776.XA patent/CN110832327A/zh active Pending
- 2018-05-03 IL IL270285A patent/IL270285B2/en unknown
- 2018-05-03 KR KR1020237044845A patent/KR20240006702A/ko not_active Ceased
- 2018-05-03 CA CA3062082A patent/CA3062082A1/en active Pending
-
2023
- 2023-04-12 JP JP2023064753A patent/JP2023098996A/ja active Pending
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