JP2020517283A5 - - Google Patents
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- JP2020517283A5 JP2020517283A5 JP2019557794A JP2019557794A JP2020517283A5 JP 2020517283 A5 JP2020517283 A5 JP 2020517283A5 JP 2019557794 A JP2019557794 A JP 2019557794A JP 2019557794 A JP2019557794 A JP 2019557794A JP 2020517283 A5 JP2020517283 A5 JP 2020517283A5
- Authority
- JP
- Japan
- Prior art keywords
- tissue
- neural
- differentiation
- tissues
- pluripotent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17168051.5A EP3395942A1 (en) | 2017-04-25 | 2017-04-25 | Bi- or multi-differentiated organoid |
| EP17168051.5 | 2017-04-25 | ||
| PCT/EP2018/060559 WO2018197544A1 (en) | 2017-04-25 | 2018-04-25 | Bi- or multi-differentiated organoid |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020517283A JP2020517283A (ja) | 2020-06-18 |
| JP2020517283A5 true JP2020517283A5 (https=) | 2021-04-30 |
| JP7248590B2 JP7248590B2 (ja) | 2023-03-29 |
Family
ID=58672346
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019557794A Active JP7248590B2 (ja) | 2017-04-25 | 2018-04-25 | 二分化または多分化オルガノイド |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20210095260A1 (https=) |
| EP (2) | EP3395942A1 (https=) |
| JP (1) | JP7248590B2 (https=) |
| KR (1) | KR102692498B1 (https=) |
| CN (2) | CN110573609A (https=) |
| AU (1) | AU2018260183B2 (https=) |
| CA (1) | CA3061412A1 (https=) |
| SG (1) | SG11201909470TA (https=) |
| WO (1) | WO2018197544A1 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9719068B2 (en) | 2010-05-06 | 2017-08-01 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
| SG10201801654RA (en) | 2014-05-28 | 2018-04-27 | Childrens Hospital Med Ct | Methods and systems for converting precursor cells into gastric tissues through directed differentiation |
| AU2015331848B2 (en) | 2014-10-17 | 2022-03-03 | Children's Hospital Medical Center, D/B/A Cincinnati Children's Hospital Medical Center | In vivo model of human small intestine using pluripotent stem cells and methods of making and using same |
| CN109415685B (zh) | 2016-05-05 | 2023-07-04 | 儿童医院医疗中心 | 用于体外制造胃底组织的方法和与其相关的组合物 |
| EP4553082A3 (en) | 2016-11-04 | 2025-08-20 | Children's Hospital Medical Center | Liver organoid compositions and methods of making and using same |
| EP3548507A4 (en) | 2016-12-05 | 2020-07-15 | Children's Hospital Medical Center | COLON ORGANOIDS AND PROCESSES FOR THE PREPARATION AND USE THEREOF |
| JP7248586B2 (ja) | 2017-04-14 | 2023-03-29 | チルドレンズ ホスピタル メディカル センター | 複数ドナー幹細胞組成物およびそれを作製する方法 |
| CA3071454A1 (en) * | 2017-07-28 | 2019-01-31 | Memorial Sloan-Kettering Cancer Center | Establishing topographic organization in three-dimensional tissue culture |
| EP3694603B1 (en) | 2017-10-10 | 2026-04-08 | Children's Hospital Medical Center | Esophageal tissue and/or organoid compositions and methods of making same |
| CA3084259A1 (en) * | 2017-12-04 | 2019-06-13 | The Administrators Of The Tulane Educational Fund | Cell systems using spheroids and methods of making and using the same |
| EP3727394A4 (en) | 2017-12-21 | 2021-09-08 | Children's Hospital Medical Center | DIGITALIZED HUMAN ORGANOIDS AND METHOD OF USING THEREOF |
| EP4678727A3 (en) * | 2018-07-26 | 2026-03-11 | Children's Hospital Medical Center | Hepato-biliary-pancreatic tissues and methods of making same |
| CA3112026A1 (en) | 2018-09-12 | 2020-03-19 | Children's Hospital Medical Center | Organoid compositions for the production of hematopoietic stem cells and derivatives thereof |
| US12600943B2 (en) | 2019-02-01 | 2026-04-14 | The University Of Hong Kong | Innervated organoid compositions and methods of making same |
| AU2020283048A1 (en) | 2019-05-31 | 2021-12-23 | Children's Hospital Medical Center | Shaped organoid compositions and methods of making same |
| US12497597B2 (en) | 2019-05-31 | 2025-12-16 | Children's Hospital Medical Center | Methods of generating and expanding hematopoietic stem cells |
| EP4176062A4 (en) * | 2020-07-06 | 2024-10-16 | President and Fellows of Harvard College | PROGRAMMABLE ORGANOIDS AND THEIR PRODUCTION METHODS BY ORTHOGONAL DIFFERENTIATION AND BIOPRINTING |
| WO2022154080A1 (ja) * | 2021-01-15 | 2022-07-21 | 国立大学法人東京大学 | 複雑な活動と可塑性を示すインビトロ神経回路組織、その神経活動の観察装置およびこれを用いた物質のスクリーニング方法 |
| DE102021132190A1 (de) * | 2021-12-07 | 2023-06-22 | Eberhard Karls Universität Tübingen, Körperschaft des öffentlichen Rechts | Biokompatible Strukturen zur Verbindung und Kultivierung von biologischem Material |
| HUP2200189A2 (hu) * | 2022-05-30 | 2023-12-28 | Biotalentum Tudasfejlesztoe Kft | Új, riportert stabilan expresszáló humán indukált pluripotens õssejt |
| EP4286513A1 (en) | 2022-06-03 | 2023-12-06 | IMBA-Institut für Molekulare Biotechnologie GmbH | Triple tissue culture fusion |
| CN116286342B (zh) * | 2022-12-23 | 2025-10-28 | 山东大学 | 一种类人脑皮质芯片、3d打印类人脑皮质的方法及应用 |
| CN116129193B (zh) * | 2023-02-27 | 2024-06-11 | 重庆大学附属肿瘤医院 | 一种类器官生长预测方法、系统及设备 |
| CN118530833B (zh) * | 2024-04-02 | 2024-11-29 | 武汉大学 | 一种同步共分化的多组织或多类器官模型及其构建方法 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4829000A (en) | 1985-08-30 | 1989-05-09 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Reconstituted basement membrane complex with biological activity |
| DE10003521A1 (de) | 2000-01-27 | 2001-08-09 | Medigene Ag | Vorrichtung zum Herstellen eines dreidimensionalen Matrixkörpers, Multi-Well-Platte, Lösung zum Kultivieren von Säugerkardiomyocyten, Verfahren zum Kultivieren einer Zellkultur, Vorrichtung für die Messung isometrischer Kraftparameter von Zellkulturen sowie Verfahren zum meßbaren Verfolgen von Kontraktionen eines in eine Trägersubstanz eingelagerten Zellgewebes |
| EP1442115B9 (en) | 2001-11-15 | 2009-12-16 | Children's Medical Center Corporation | Methods of isolation, expansion and differentiation of fetal stem cells from chorionic villus, amniotic fluid, and placenta and therapeutic uses thereof |
| WO2004084950A2 (en) | 2003-03-24 | 2004-10-07 | Case Western Reserve University | Cell targeting methods and compositions |
| US20100196923A1 (en) | 2007-08-14 | 2010-08-05 | Anthony Atala | Pluripotent adult stem cells |
| EP2028268A1 (en) * | 2007-08-20 | 2009-02-25 | Université Libre De Bruxelles | Generation of neuronal cells from pluripotent stem cells |
| US20110143433A1 (en) | 2008-03-17 | 2011-06-16 | Agency For Science, Technology And Research | Microcarriers for Stem Cell Culture |
| JP5787370B2 (ja) | 2009-11-05 | 2015-09-30 | 国立研究開発法人理化学研究所 | 幹細胞の分化誘導方法 |
| WO2012013936A1 (en) * | 2010-07-30 | 2012-02-02 | Cambridge Enterprise Limited | Corticogenesis of human pluripotent cells |
| CN104903440B (zh) | 2012-09-03 | 2018-04-06 | 诺和诺德股份有限公司 | 使用小分子从多能干细胞产生胰内胚层 |
| EP2743345A1 (en) * | 2012-12-13 | 2014-06-18 | IMBA-Institut für Molekulare Biotechnologie GmbH | Three dimensional heterogeneously differentiated tissue culture |
| KR101381798B1 (ko) * | 2013-02-27 | 2014-04-07 | 씨제이제일제당 (주) | 신규 박테리오파지 및 이를 포함하는 항균 조성물 |
| US9677085B2 (en) * | 2013-03-18 | 2017-06-13 | Massachusetts Institute Of Technology | Engineering a heterogeneous tissue from pluripotent stem cells |
| EP3498824A1 (en) * | 2013-04-26 | 2019-06-19 | Memorial Sloan-Kettering Cancer Center | Cortical interneurons and other neuronal cells produced by the directed differentiation of pluripotent and multipotent cells |
| US10794802B2 (en) * | 2013-09-20 | 2020-10-06 | California Institute Of Technology | Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high resolution intact circuit mapping and phenotyping |
| WO2015069736A1 (en) * | 2013-11-08 | 2015-05-14 | The Mclean Hospital Corporation | METHODS FOR EFFICIENT GENERATION OF GABAergic INTERNEURONS FROM PLURIPOTENT STEM CELLS |
| ES2732730T3 (es) | 2013-11-22 | 2019-11-25 | Riken | Método para producir telencéfalo o tejido progenitor del mismo |
| US10081792B2 (en) * | 2014-12-31 | 2018-09-25 | Wisconsin Alumni Research Foundation | Derivation of human microglia from pluripotent stem cells |
| CN107427537A (zh) | 2015-03-03 | 2017-12-01 | 哈佛学院院长及董事 | 产生功能性人体组织的方法 |
| US10087417B2 (en) * | 2015-04-22 | 2018-10-02 | William J. Freed | Three-dimensional model of human cortex |
| US10081791B2 (en) * | 2015-05-07 | 2018-09-25 | William J. Freed | Modeling connections between dopaminergic neurons and the cerebral cortex |
| LU92845B1 (en) * | 2015-10-08 | 2017-05-02 | Univ Du Luxembourg Campus Belval | Means and methods for generating midbrain organoids |
| WO2017083705A1 (en) * | 2015-11-13 | 2017-05-18 | The Johns Hopkins University | Cell culture system and method of use thereof |
| WO2017117547A1 (en) * | 2015-12-31 | 2017-07-06 | President And Fellows Of Harvard College | Methods for generating neural tissue and uses thereof |
| WO2017160234A1 (en) * | 2016-03-14 | 2017-09-21 | Agency For Science, Technology And Research | Generation of midbrain-specific organoids from human pluripotent stem cells |
| FR3058892B1 (fr) * | 2016-11-23 | 2021-04-09 | Univ Bordeaux | Unite de tissu neural et utilisation d'une telle unite pour l'implantation dans le systeme nerveux d'un mammifere |
| EP3600362B1 (en) * | 2017-03-28 | 2023-12-13 | The Board of Trustees of the Leland Stanford Junior University | Assembly of functionally integrated human forebrain spheroids and methods of use thereof |
| CN110494454B (zh) * | 2017-03-29 | 2022-03-15 | 伊士曼化工公司 | 区域选择性取代的纤维素酯 |
| GB201900930D0 (en) * | 2019-01-23 | 2019-03-13 | Res & Innovation Uk | Choroid plexus organoids and methods for productions thereof |
| WO2020247336A1 (en) * | 2019-06-03 | 2020-12-10 | The Regents Of The University Of California | Pifithrin analogues and methods of treating rett syndrome |
-
2017
- 2017-04-25 EP EP17168051.5A patent/EP3395942A1/en not_active Withdrawn
-
2018
- 2018-04-25 CA CA3061412A patent/CA3061412A1/en active Pending
- 2018-04-25 WO PCT/EP2018/060559 patent/WO2018197544A1/en not_active Ceased
- 2018-04-25 JP JP2019557794A patent/JP7248590B2/ja active Active
- 2018-04-25 CN CN201880027801.3A patent/CN110573609A/zh active Pending
- 2018-04-25 EP EP18720229.6A patent/EP3615661B1/en active Active
- 2018-04-25 CN CN202411042018.8A patent/CN119101651A/zh active Pending
- 2018-04-25 US US16/608,719 patent/US20210095260A1/en active Pending
- 2018-04-25 KR KR1020197034778A patent/KR102692498B1/ko active Active
- 2018-04-25 AU AU2018260183A patent/AU2018260183B2/en active Active
- 2018-04-25 SG SG11201909470T patent/SG11201909470TA/en unknown
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