JP2020517283A5 - - Google Patents
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- JP2020517283A5 JP2020517283A5 JP2019557794A JP2019557794A JP2020517283A5 JP 2020517283 A5 JP2020517283 A5 JP 2020517283A5 JP 2019557794 A JP2019557794 A JP 2019557794A JP 2019557794 A JP2019557794 A JP 2019557794A JP 2020517283 A5 JP2020517283 A5 JP 2020517283A5
- Authority
- JP
- Japan
- Prior art keywords
- tissue
- neural
- differentiation
- tissues
- pluripotent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17168051.5A EP3395942A1 (en) | 2017-04-25 | 2017-04-25 | Bi- or multi-differentiated organoid |
| EP17168051.5 | 2017-04-25 | ||
| PCT/EP2018/060559 WO2018197544A1 (en) | 2017-04-25 | 2018-04-25 | Bi- or multi-differentiated organoid |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020517283A JP2020517283A (ja) | 2020-06-18 |
| JP2020517283A5 true JP2020517283A5 (https=) | 2021-04-30 |
| JP7248590B2 JP7248590B2 (ja) | 2023-03-29 |
Family
ID=58672346
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019557794A Active JP7248590B2 (ja) | 2017-04-25 | 2018-04-25 | 二分化または多分化オルガノイド |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20210095260A1 (https=) |
| EP (2) | EP3395942A1 (https=) |
| JP (1) | JP7248590B2 (https=) |
| KR (1) | KR102692498B1 (https=) |
| CN (2) | CN110573609A (https=) |
| AU (1) | AU2018260183B2 (https=) |
| CA (1) | CA3061412A1 (https=) |
| SG (1) | SG11201909470TA (https=) |
| WO (1) | WO2018197544A1 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9719068B2 (en) | 2010-05-06 | 2017-08-01 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
| CN106661548B (zh) | 2014-05-28 | 2020-12-11 | 儿童医院医疗中心 | 用于经由定向分化将前体细胞转化为胃组织的方法和系统 |
| JP6804438B2 (ja) | 2014-10-17 | 2020-12-23 | チルドレンズ ホスピタル メディカル センター | 多能性幹細胞を使用するヒト小腸のｉｎ ｖｉｖｏモデル、並びにそれを作製、及び使用する方法 |
| ES2929758T3 (es) | 2016-05-05 | 2022-12-01 | Childrens Hospital Med Ct | Métodos para la fabricación in vitro de tejido del fondo gástrico y composiciones relacionadas con el mismo |
| KR102729404B1 (ko) | 2016-11-04 | 2024-11-14 | 칠드런즈 호스피탈 메디칼 센터 | 간 유사 장기 조성물 및 이를 제조 및 사용하는 방법 |
| JP7068305B2 (ja) | 2016-12-05 | 2022-05-16 | チルドレンズ ホスピタル メディカル センター | 結腸オルガノイドならびにその作製方法および使用方法 |
| US12281334B2 (en) | 2017-04-14 | 2025-04-22 | Children's Hospital Medical Center | Multi donor stem cell compositions and methods of making same |
| CA3071454A1 (en) * | 2017-07-28 | 2019-01-31 | Memorial Sloan-Kettering Cancer Center | Establishing topographic organization in three-dimensional tissue culture |
| EP3694603B1 (en) | 2017-10-10 | 2026-04-08 | Children's Hospital Medical Center | Esophageal tissue and/or organoid compositions and methods of making same |
| EP3720452A4 (en) * | 2017-12-04 | 2022-02-23 | The Administrators of The Tulane Educational Fund | CELL SYSTEMS USING SPHEROIDS AND METHODS FOR THEIR MANUFACTURE AND USE |
| US12379372B2 (en) | 2017-12-21 | 2025-08-05 | Children's Hospital Medical Center | Digitalized human organoids and methods of using same |
| KR102887406B1 (ko) | 2018-07-26 | 2025-11-19 | 칠드런즈 호스피탈 메디칼 센터 | 간-담도-췌장 조직 및 이를 제조하는 방법 |
| AU2019339410A1 (en) | 2018-09-12 | 2021-04-15 | Children's Hospital Medical Center | Organoid compositions for the production of hematopoietic stem cells and derivatives thereof |
| WO2020160371A1 (en) | 2019-02-01 | 2020-08-06 | The University Of Hong Kong | Innervated organoid compositions and methods of making same |
| WO2020243633A1 (en) | 2019-05-31 | 2020-12-03 | Children's Hospital Medical Center | Shaped organoid compositions and methods of making same |
| WO2020243613A1 (en) | 2019-05-31 | 2020-12-03 | Children's Hospital Medical Center | Methods of generating and expanding hematopoietic stem cells |
| WO2022010901A2 (en) * | 2020-07-06 | 2022-01-13 | President And Fellows Of Harvard College | Programmable organoids and methods of producing the same via orthogonal differentiation and bioprinting |
| WO2022154080A1 (ja) * | 2021-01-15 | 2022-07-21 | 国立大学法人東京大学 | 複雑な活動と可塑性を示すインビトロ神経回路組織、その神経活動の観察装置およびこれを用いた物質のスクリーニング方法 |
| DE102021132190A1 (de) * | 2021-12-07 | 2023-06-22 | Eberhard Karls Universität Tübingen, Körperschaft des öffentlichen Rechts | Biokompatible Strukturen zur Verbindung und Kultivierung von biologischem Material |
| HUP2200189A2 (hu) * | 2022-05-30 | 2023-12-28 | Biotalentum Tudasfejlesztoe Kft | Új, riportert stabilan expresszáló humán indukált pluripotens õssejt |
| EP4286513A1 (en) | 2022-06-03 | 2023-12-06 | IMBA-Institut für Molekulare Biotechnologie GmbH | Triple tissue culture fusion |
| CN116286342B (zh) * | 2022-12-23 | 2025-10-28 | 山东大学 | 一种类人脑皮质芯片、3d打印类人脑皮质的方法及应用 |
| CN116129193B (zh) * | 2023-02-27 | 2024-06-11 | 重庆大学附属肿瘤医院 | 一种类器官生长预测方法、系统及设备 |
| CN118530833B (zh) * | 2024-04-02 | 2024-11-29 | 武汉大学 | 一种同步共分化的多组织或多类器官模型及其构建方法 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4829000A (en) | 1985-08-30 | 1989-05-09 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Reconstituted basement membrane complex with biological activity |
| DE10003521A1 (de) | 2000-01-27 | 2001-08-09 | Medigene Ag | Vorrichtung zum Herstellen eines dreidimensionalen Matrixkörpers, Multi-Well-Platte, Lösung zum Kultivieren von Säugerkardiomyocyten, Verfahren zum Kultivieren einer Zellkultur, Vorrichtung für die Messung isometrischer Kraftparameter von Zellkulturen sowie Verfahren zum meßbaren Verfolgen von Kontraktionen eines in eine Trägersubstanz eingelagerten Zellgewebes |
| JP4330995B2 (ja) | 2001-11-15 | 2009-09-16 | チルドレンズ メディカル センター コーポレーション | 絨毛膜絨毛、羊水、および胎盤からの胎児性幹細胞を単離、増殖、および分化させる方法、ならびにその治療的使用方法 |
| WO2004084950A2 (en) | 2003-03-24 | 2004-10-07 | Case Western Reserve University | Cell targeting methods and compositions |
| US20100196923A1 (en) | 2007-08-14 | 2010-08-05 | Anthony Atala | Pluripotent adult stem cells |
| EP2028268A1 (en) * | 2007-08-20 | 2009-02-25 | Université Libre De Bruxelles | Generation of neuronal cells from pluripotent stem cells |
| US20110143433A1 (en) | 2008-03-17 | 2011-06-16 | Agency For Science, Technology And Research | Microcarriers for Stem Cell Culture |
| JP5787370B2 (ja) | 2009-11-05 | 2015-09-30 | 国立研究開発法人理化学研究所 | 幹細胞の分化誘導方法 |
| WO2012013936A1 (en) * | 2010-07-30 | 2012-02-02 | Cambridge Enterprise Limited | Corticogenesis of human pluripotent cells |
| EP2893000B1 (en) * | 2012-09-03 | 2019-04-10 | Novo Nordisk A/S | Generation of pancreatic endoderm from pluripotent stem cells using small molecules |
| EP2743345A1 (en) | 2012-12-13 | 2014-06-18 | IMBA-Institut für Molekulare Biotechnologie GmbH | Three dimensional heterogeneously differentiated tissue culture |
| KR101381798B1 (ko) * | 2013-02-27 | 2014-04-07 | 씨제이제일제당 (주) | 신규 박테리오파지 및 이를 포함하는 항균 조성물 |
| WO2014153346A1 (en) * | 2013-03-18 | 2014-09-25 | Massachusetts Institute Of Technology | Engineering a heterogeneous tissue pluripotent stem cells |
| EP3498824A1 (en) * | 2013-04-26 | 2019-06-19 | Memorial Sloan-Kettering Cancer Center | Cortical interneurons and other neuronal cells produced by the directed differentiation of pluripotent and multipotent cells |
| US10794802B2 (en) * | 2013-09-20 | 2020-10-06 | California Institute Of Technology | Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high resolution intact circuit mapping and phenotyping |
| WO2015069736A1 (en) * | 2013-11-08 | 2015-05-14 | The Mclean Hospital Corporation | METHODS FOR EFFICIENT GENERATION OF GABAergic INTERNEURONS FROM PLURIPOTENT STEM CELLS |
| JP6499084B2 (ja) | 2013-11-22 | 2019-04-10 | 国立研究開発法人理化学研究所 | 終脳又はその前駆組織の製造方法 |
| US10081792B2 (en) * | 2014-12-31 | 2018-09-25 | Wisconsin Alumni Research Foundation | Derivation of human microglia from pluripotent stem cells |
| JP6807853B2 (ja) | 2015-03-03 | 2021-01-06 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 機能的ヒト組織の作製方法 |
| US10087417B2 (en) * | 2015-04-22 | 2018-10-02 | William J. Freed | Three-dimensional model of human cortex |
| US10081791B2 (en) * | 2015-05-07 | 2018-09-25 | William J. Freed | Modeling connections between dopaminergic neurons and the cerebral cortex |
| LU92845B1 (en) * | 2015-10-08 | 2017-05-02 | Univ Du Luxembourg Campus Belval | Means and methods for generating midbrain organoids |
| WO2017083705A1 (en) * | 2015-11-13 | 2017-05-18 | The Johns Hopkins University | Cell culture system and method of use thereof |
| WO2017117547A1 (en) * | 2015-12-31 | 2017-07-06 | President And Fellows Of Harvard College | Methods for generating neural tissue and uses thereof |
| SG11201807487WA (en) * | 2016-03-14 | 2018-09-27 | Agency Science Tech & Res | Generation of midbrain-specific organoids from human pluripotent stem cells |
| FR3058892B1 (fr) * | 2016-11-23 | 2021-04-09 | Univ Bordeaux | Unite de tissu neural et utilisation d'une telle unite pour l'implantation dans le systeme nerveux d'un mammifere |
| EP3600362B1 (en) * | 2017-03-28 | 2023-12-13 | The Board of Trustees of the Leland Stanford Junior University | Assembly of functionally integrated human forebrain spheroids and methods of use thereof |
| KR20240124440A (ko) * | 2017-03-29 | 2024-08-16 | 이스트만 케미칼 컴파니 | 위치-선택적으로 치환된 셀룰로스 에스터 |
| GB201900930D0 (en) * | 2019-01-23 | 2019-03-13 | Res & Innovation Uk | Choroid plexus organoids and methods for productions thereof |
| WO2020247336A1 (en) * | 2019-06-03 | 2020-12-10 | The Regents Of The University Of California | Pifithrin analogues and methods of treating rett syndrome |
-
2017
- 2017-04-25 EP EP17168051.5A patent/EP3395942A1/en not_active Withdrawn
-
2018
- 2018-04-25 JP JP2019557794A patent/JP7248590B2/ja active Active
- 2018-04-25 SG SG11201909470T patent/SG11201909470TA/en unknown
- 2018-04-25 CN CN201880027801.3A patent/CN110573609A/zh active Pending
- 2018-04-25 EP EP18720229.6A patent/EP3615661B1/en active Active
- 2018-04-25 AU AU2018260183A patent/AU2018260183B2/en active Active
- 2018-04-25 CN CN202411042018.8A patent/CN119101651A/zh active Pending
- 2018-04-25 CA CA3061412A patent/CA3061412A1/en active Pending
- 2018-04-25 US US16/608,719 patent/US20210095260A1/en active Pending
- 2018-04-25 WO PCT/EP2018/060559 patent/WO2018197544A1/en not_active Ceased
- 2018-04-25 KR KR1020197034778A patent/KR102692498B1/ko active Active
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