CN110573609A - 双分化或多分化类器官 - Google Patents

双分化或多分化类器官 Download PDF

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Publication number
CN110573609A
CN110573609A CN201880027801.3A CN201880027801A CN110573609A CN 110573609 A CN110573609 A CN 110573609A CN 201880027801 A CN201880027801 A CN 201880027801A CN 110573609 A CN110573609 A CN 110573609A
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tissue
cells
ventral
differentiation
tissues
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Chinese (zh)
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J.诺布里奇
J.A.巴格利
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Imba Molikul Institute Of Biotechnology
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Imba Molikul Institute Of Biotechnology
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Priority to CN202411042018.8A priority Critical patent/CN119101651A/zh
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0619—Neurons
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    • C12N2500/99—Serum-free medium
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2502/00—Coculture with; Conditioned medium produced by
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
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    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/54—Collagen; Gelatin

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  • Health & Medical Sciences (AREA)
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  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN201880027801.3A 2017-04-25 2018-04-25 双分化或多分化类器官 Pending CN110573609A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202411042018.8A CN119101651A (zh) 2017-04-25 2018-04-25 双分化或多分化类器官

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17168051.5A EP3395942A1 (en) 2017-04-25 2017-04-25 Bi- or multi-differentiated organoid
EP17168051.5 2017-04-25
PCT/EP2018/060559 WO2018197544A1 (en) 2017-04-25 2018-04-25 Bi- or multi-differentiated organoid

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US (1) US20210095260A1 (https=)
EP (2) EP3395942A1 (https=)
JP (1) JP7248590B2 (https=)
KR (1) KR102692498B1 (https=)
CN (2) CN110573609A (https=)
AU (1) AU2018260183B2 (https=)
CA (1) CA3061412A1 (https=)
SG (1) SG11201909470TA (https=)
WO (1) WO2018197544A1 (https=)

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CN116129193A (zh) * 2023-02-27 2023-05-16 重庆大学附属肿瘤医院 一种类器官生长预测方法、系统及设备
CN118530833A (zh) * 2024-04-02 2024-08-23 武汉大学 一种同步共分化的多组织或多类器官模型及其构建方法

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AU2015331848B2 (en) 2014-10-17 2022-03-03 Children's Hospital Medical Center, D/B/A Cincinnati Children's Hospital Medical Center In vivo model of human small intestine using pluripotent stem cells and methods of making and using same
CN109415685B (zh) 2016-05-05 2023-07-04 儿童医院医疗中心 用于体外制造胃底组织的方法和与其相关的组合物
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JP7248586B2 (ja) 2017-04-14 2023-03-29 チルドレンズ ホスピタル メディカル センター 複数ドナー幹細胞組成物およびそれを作製する方法
CA3071454A1 (en) * 2017-07-28 2019-01-31 Memorial Sloan-Kettering Cancer Center Establishing topographic organization in three-dimensional tissue culture
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CA3084259A1 (en) * 2017-12-04 2019-06-13 The Administrators Of The Tulane Educational Fund Cell systems using spheroids and methods of making and using the same
EP3727394A4 (en) 2017-12-21 2021-09-08 Children's Hospital Medical Center DIGITALIZED HUMAN ORGANOIDS AND METHOD OF USING THEREOF
EP4678727A3 (en) * 2018-07-26 2026-03-11 Children's Hospital Medical Center Hepato-biliary-pancreatic tissues and methods of making same
CA3112026A1 (en) 2018-09-12 2020-03-19 Children's Hospital Medical Center Organoid compositions for the production of hematopoietic stem cells and derivatives thereof
US12600943B2 (en) 2019-02-01 2026-04-14 The University Of Hong Kong Innervated organoid compositions and methods of making same
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US12497597B2 (en) 2019-05-31 2025-12-16 Children's Hospital Medical Center Methods of generating and expanding hematopoietic stem cells
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Cited By (4)

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Publication number Priority date Publication date Assignee Title
CN116129193A (zh) * 2023-02-27 2023-05-16 重庆大学附属肿瘤医院 一种类器官生长预测方法、系统及设备
CN116129193B (zh) * 2023-02-27 2024-06-11 重庆大学附属肿瘤医院 一种类器官生长预测方法、系统及设备
CN118530833A (zh) * 2024-04-02 2024-08-23 武汉大学 一种同步共分化的多组织或多类器官模型及其构建方法
CN118530833B (zh) * 2024-04-02 2024-11-29 武汉大学 一种同步共分化的多组织或多类器官模型及其构建方法

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EP3615661B1 (en) 2026-02-11
JP7248590B2 (ja) 2023-03-29
KR102692498B1 (ko) 2024-08-05
EP3615661A1 (en) 2020-03-04
EP3395942A1 (en) 2018-10-31
CN119101651A (zh) 2024-12-10
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