JP2020514369A5 - - Google Patents
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- Publication number
- JP2020514369A5 JP2020514369A5 JP2019550787A JP2019550787A JP2020514369A5 JP 2020514369 A5 JP2020514369 A5 JP 2020514369A5 JP 2019550787 A JP2019550787 A JP 2019550787A JP 2019550787 A JP2019550787 A JP 2019550787A JP 2020514369 A5 JP2020514369 A5 JP 2020514369A5
- Authority
- JP
- Japan
- Prior art keywords
- loxl2
- antibody
- kit
- cancer
- immunoassay
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 16
- 101001043352 Homo sapiens Lysyl oxidase homolog 2 Proteins 0.000 claims 13
- 102100021948 Lysyl oxidase homolog 2 Human genes 0.000 claims 13
- 238000003018 immunoassay Methods 0.000 claims 6
- 201000010099 disease Diseases 0.000 claims 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 5
- 239000003814 drug Substances 0.000 claims 4
- 229940124597 therapeutic agent Drugs 0.000 claims 4
- 201000009794 Idiopathic Pulmonary Fibrosis Diseases 0.000 claims 2
- 125000001429 N-terminal alpha-amino-acid group Chemical group 0.000 claims 2
- 206010041067 Small cell lung cancer Diseases 0.000 claims 2
- 210000004381 amniotic fluid Anatomy 0.000 claims 2
- 238000003556 assay Methods 0.000 claims 2
- 208000036971 interstitial lung disease 2 Diseases 0.000 claims 2
- 208000002154 non-small cell lung carcinoma Diseases 0.000 claims 2
- 210000002381 plasma Anatomy 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 210000002966 serum Anatomy 0.000 claims 2
- 208000000587 small cell lung carcinoma Diseases 0.000 claims 2
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 claims 2
- 210000002700 urine Anatomy 0.000 claims 2
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims 1
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 206010016654 Fibrosis Diseases 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 206010033128 Ovarian cancer Diseases 0.000 claims 1
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 1
- 206010060862 Prostate cancer Diseases 0.000 claims 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
- 108010090804 Streptavidin Proteins 0.000 claims 1
- 239000005557 antagonist Substances 0.000 claims 1
- 239000013060 biological fluid Substances 0.000 claims 1
- 229960000106 biosimilars Drugs 0.000 claims 1
- 229960002685 biotin Drugs 0.000 claims 1
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N biotin Natural products N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 1
- 235000020958 biotin Nutrition 0.000 claims 1
- 239000011616 biotin Substances 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 208000029742 colonic neoplasm Diseases 0.000 claims 1
- 230000002596 correlated effect Effects 0.000 claims 1
- 230000004761 fibrosis Effects 0.000 claims 1
- 238000002372 labelling Methods 0.000 claims 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 1
- 201000001441 melanoma Diseases 0.000 claims 1
- 201000002528 pancreatic cancer Diseases 0.000 claims 1
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 1
- 238000000163 radioactive labelling Methods 0.000 claims 1
- 238000003127 radioimmunoassay Methods 0.000 claims 1
- 150000003384 small molecules Chemical group 0.000 claims 1
- 238000012800 visualization Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1704206.0A GB201704206D0 (en) | 2017-03-16 | 2017-03-16 | Lysyl oxidase like-2 assay |
| GB1704206.0 | 2017-03-16 | ||
| PCT/EP2018/056364 WO2018167132A1 (en) | 2017-03-16 | 2018-03-14 | Lysyl oxidase like-2 assay |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020514369A JP2020514369A (ja) | 2020-05-21 |
| JP2020514369A5 true JP2020514369A5 (enExample) | 2021-04-22 |
Family
ID=58688361
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019550787A Pending JP2020514369A (ja) | 2017-03-16 | 2018-03-14 | リシルオキシダーゼ様２アッセイ |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20200123272A1 (enExample) |
| EP (1) | EP3596127A1 (enExample) |
| JP (1) | JP2020514369A (enExample) |
| GB (1) | GB201704206D0 (enExample) |
| WO (1) | WO2018167132A1 (enExample) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2015108348A (ru) * | 2010-02-04 | 2015-07-20 | Джилид Байолоджикс, Инк. | Антитела, связывающиеся с лизилоксидазоподобным ферментом-2 (loxl2), и способы их применения |
| US20140206017A1 (en) | 2011-06-01 | 2014-07-24 | Victoria Smith | Lysyl oxidase-like 2 assay and methods of use thereof |
| SG11201503065PA (en) * | 2012-10-30 | 2015-05-28 | Gilead Sciences Inc | Therapeutic and diagnostic methods related to lysyl oxidase-like 2 (loxl2) |
-
2017
- 2017-03-16 GB GBGB1704206.0A patent/GB201704206D0/en not_active Ceased
-
2018
- 2018-03-14 US US16/494,472 patent/US20200123272A1/en not_active Abandoned
- 2018-03-14 EP EP18713814.4A patent/EP3596127A1/en not_active Withdrawn
- 2018-03-14 WO PCT/EP2018/056364 patent/WO2018167132A1/en not_active Ceased
- 2018-03-14 JP JP2019550787A patent/JP2020514369A/ja active Pending
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