JP2020514368A5 - - Google Patents
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- Publication number
- JP2020514368A5 JP2020514368A5 JP2019550764A JP2019550764A JP2020514368A5 JP 2020514368 A5 JP2020514368 A5 JP 2020514368A5 JP 2019550764 A JP2019550764 A JP 2019550764A JP 2019550764 A JP2019550764 A JP 2019550764A JP 2020514368 A5 JP2020514368 A5 JP 2020514368A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- time point
- xviii
- collagen
- hemophiliac
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 20
- 102000001708 Protein Isoforms Human genes 0.000 claims 9
- 108010029485 Protein Isoforms Proteins 0.000 claims 9
- 201000010099 disease Diseases 0.000 claims 9
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 9
- 102000008186 Collagen Human genes 0.000 claims 8
- 108010035532 Collagen Proteins 0.000 claims 8
- 229920001436 collagen Polymers 0.000 claims 8
- 102000047200 Collagen Type XVIII Human genes 0.000 claims 6
- 108010001463 Collagen Type XVIII Proteins 0.000 claims 6
- 125000001429 N-terminal alpha-amino-acid group Chemical group 0.000 claims 4
- 229940079593 drug Drugs 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 4
- 238000003018 immunoassay Methods 0.000 claims 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims 3
- 238000003556 assay Methods 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 208000036487 Arthropathies Diseases 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 208000012659 Joint disease Diseases 0.000 claims 1
- 108010090804 Streptavidin Proteins 0.000 claims 1
- 210000004381 amniotic fluid Anatomy 0.000 claims 1
- 238000003149 assay kit Methods 0.000 claims 1
- 239000013060 biological fluid Substances 0.000 claims 1
- 229960002685 biotin Drugs 0.000 claims 1
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N biotin Natural products N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 1
- 235000020958 biotin Nutrition 0.000 claims 1
- 239000011616 biotin Substances 0.000 claims 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims 1
- 238000012875 competitive assay Methods 0.000 claims 1
- 230000005713 exacerbation Effects 0.000 claims 1
- 238000002372 labelling Methods 0.000 claims 1
- 210000002381 plasma Anatomy 0.000 claims 1
- 238000000163 radioactive labelling Methods 0.000 claims 1
- 238000003127 radioimmunoassay Methods 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
- 238000012800 visualization Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1704182.3 | 2017-03-16 | ||
| GBGB1704182.3A GB201704182D0 (en) | 2017-03-16 | 2017-03-16 | Collagen tye XVIII assay |
| PCT/EP2018/056320 WO2018167111A1 (en) | 2017-03-16 | 2018-03-14 | Collagen type xviii assay |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020514368A JP2020514368A (ja) | 2020-05-21 |
| JP2020514368A5 true JP2020514368A5 (enExample) | 2021-04-30 |
| JP7275040B2 JP7275040B2 (ja) | 2023-05-17 |
Family
ID=58688412
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019550764A Active JP7275040B2 (ja) | 2017-03-16 | 2018-03-14 | Ｘｖｉｉｉ型コラーゲンアッセイ |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20200087385A1 (enExample) |
| EP (1) | EP3596120B1 (enExample) |
| JP (1) | JP7275040B2 (enExample) |
| ES (1) | ES2969042T3 (enExample) |
| GB (1) | GB201704182D0 (enExample) |
| WO (1) | WO2018167111A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201901710D0 (en) * | 2019-02-07 | 2019-03-27 | Nordic Bioscience As | Collagen type 23 assay |
| GB202019578D0 (en) * | 2020-12-11 | 2021-01-27 | Nordic Bioscience As | Assay for detecting Collagen XVIII biomarkers |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2007049749A1 (ja) | 2005-10-28 | 2009-04-30 | ディナベック株式会社 | 血液凝固異常の治療方法 |
-
2017
- 2017-03-16 GB GBGB1704182.3A patent/GB201704182D0/en not_active Ceased
-
2018
- 2018-03-14 WO PCT/EP2018/056320 patent/WO2018167111A1/en not_active Ceased
- 2018-03-14 EP EP18713147.9A patent/EP3596120B1/en active Active
- 2018-03-14 US US16/494,441 patent/US20200087385A1/en not_active Abandoned
- 2018-03-14 JP JP2019550764A patent/JP7275040B2/ja active Active
- 2018-03-14 ES ES18713147T patent/ES2969042T3/es active Active
-
2022
- 2022-12-22 US US18/145,767 patent/US20230340092A1/en active Pending
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