JP2012521745A5 - - Google Patents
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- Publication number
- JP2012521745A5 JP2012521745A5 JP2012501093A JP2012501093A JP2012521745A5 JP 2012521745 A5 JP2012521745 A5 JP 2012521745A5 JP 2012501093 A JP2012501093 A JP 2012501093A JP 2012501093 A JP2012501093 A JP 2012501093A JP 2012521745 A5 JP2012521745 A5 JP 2012521745A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- mitochondrial fusion
- mammal
- acid sequence
- isolated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010028980 Neoplasm Diseases 0.000 claims 10
- 201000011510 cancer Diseases 0.000 claims 10
- 230000002438 mitochondrial effect Effects 0.000 claims 10
- 230000004927 fusion Effects 0.000 claims 7
- 241000124008 Mammalia Species 0.000 claims 6
- 108020001507 fusion proteins Proteins 0.000 claims 5
- 102000037865 fusion proteins Human genes 0.000 claims 5
- 239000000523 sample Substances 0.000 claims 5
- 108020005196 Mitochondrial DNA Proteins 0.000 claims 4
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 4
- 239000000427 antigen Substances 0.000 claims 4
- 108091007433 antigens Proteins 0.000 claims 4
- 102000036639 antigens Human genes 0.000 claims 4
- 238000003556 assay Methods 0.000 claims 4
- 239000012634 fragment Substances 0.000 claims 4
- 150000007523 nucleic acids Chemical group 0.000 claims 4
- 230000000295 complement effect Effects 0.000 claims 3
- 238000009396 hybridization Methods 0.000 claims 3
- 206010006187 Breast cancer Diseases 0.000 claims 2
- 208000026310 Breast neoplasm Diseases 0.000 claims 2
- 206010009944 Colon cancer Diseases 0.000 claims 2
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 2
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 2
- 206010033128 Ovarian cancer Diseases 0.000 claims 2
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 2
- 206010060862 Prostate cancer Diseases 0.000 claims 2
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 2
- 208000024313 Testicular Neoplasms Diseases 0.000 claims 2
- 206010057644 Testis cancer Diseases 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 208000030381 cutaneous melanoma Diseases 0.000 claims 2
- 201000005202 lung cancer Diseases 0.000 claims 2
- 208000020816 lung neoplasm Diseases 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 201000001441 melanoma Diseases 0.000 claims 2
- 201000003120 testicular cancer Diseases 0.000 claims 2
- 210000001519 tissue Anatomy 0.000 claims 2
- 238000010324 immunological assay Methods 0.000 claims 1
- 230000035772 mutation Effects 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CAPCT/CA2009/000351 | 2009-03-27 | ||
| PCT/CA2009/000351 WO2009117811A1 (en) | 2008-03-28 | 2009-03-27 | Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes therefor |
| PCT/CA2010/000423 WO2010115261A1 (en) | 2009-03-27 | 2010-03-29 | Aberrant mitochondrial dna, associated fusion transcripts and translation products and hybridization probes therefor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012521745A JP2012521745A (ja) | 2012-09-20 |
| JP2012521745A5 true JP2012521745A5 (enExample) | 2013-05-16 |
| JP5734947B2 JP5734947B2 (ja) | 2015-06-17 |
Family
ID=42937093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012501093A Expired - Fee Related JP5734947B2 (ja) | 2009-03-27 | 2010-03-29 | 異常型ミトコンドリアｄｎａ、関連融合転写物および翻訳産物、並びにそのハイブリダイゼーションプローブ |
Country Status (6)
| Country | Link |
|---|---|
| EP (2) | EP2411522B1 (enExample) |
| JP (1) | JP5734947B2 (enExample) |
| KR (1) | KR101720555B1 (enExample) |
| AU (1) | AU2010234238B2 (enExample) |
| RU (1) | RU2011137486A (enExample) |
| WO (1) | WO2010115261A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101693387B1 (ko) | 2008-03-28 | 2017-01-05 | 엠디엔에이 라이프 사이언시즈 인코퍼레이티드 | 비정상적인 미토콘드리아 ｄｎａ, 그것에 연관된 융합 트랜스크립트 및 혼성화 프로브 |
| TWI709188B (zh) | 2018-09-27 | 2020-11-01 | 財團法人工業技術研究院 | 基於機率融合的分類器、分類方法及分類系統 |
| CN113025633B (zh) * | 2019-12-09 | 2024-08-27 | 武汉纽福斯生物科技有限公司 | 编码人nadh脱氢酶亚单位1蛋白的核酸及其应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| US3817837A (en) | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
| US3939350A (en) | 1974-04-29 | 1976-02-17 | Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing total reflection for activation |
| US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4277437A (en) | 1978-04-05 | 1981-07-07 | Syva Company | Kit for carrying out chemically induced fluorescence immunoassay |
| US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
| US5807522A (en) | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
| US6218117B1 (en) * | 1998-06-15 | 2001-04-17 | Mitokor | Compositions and methods for identifying agents that quantitatively alter detectable extramitochondrial DNA:mitochondrial DNA ratios |
| US20030162174A1 (en) * | 2001-06-11 | 2003-08-28 | Sutherland John W. | Detecting nucleic acid deletion sequences |
| WO2002101086A2 (en) * | 2001-06-11 | 2002-12-19 | 1304854 Ontario Ltd. | Complete mitochondrial genome sequences as a diagnostic tool for the health sciences |
| DE602006017534D1 (de) * | 2005-04-18 | 2010-11-25 | Mitomics Inc | Mitochondriale mutationen und umlagerungen als diagnostisches werkzeug zum nachweis von sonneneinstrahlung, prostatakrebs und anderen krebserkrankungen |
| EP2634267B1 (en) * | 2007-09-26 | 2015-02-18 | Mitomics Inc. | 3.4 kb mitochondrial DNA deletion for use in the detection of cancer |
| KR101693387B1 (ko) * | 2008-03-28 | 2017-01-05 | 엠디엔에이 라이프 사이언시즈 인코퍼레이티드 | 비정상적인 미토콘드리아 ｄｎａ, 그것에 연관된 융합 트랜스크립트 및 혼성화 프로브 |
-
2010
- 2010-03-29 AU AU2010234238A patent/AU2010234238B2/en not_active Ceased
- 2010-03-29 WO PCT/CA2010/000423 patent/WO2010115261A1/en not_active Ceased
- 2010-03-29 EP EP10761136.0A patent/EP2411522B1/en not_active Not-in-force
- 2010-03-29 KR KR1020117025261A patent/KR101720555B1/ko not_active Expired - Fee Related
- 2010-03-29 JP JP2012501093A patent/JP5734947B2/ja not_active Expired - Fee Related
- 2010-03-29 EP EP17188792.0A patent/EP3272871B1/en active Active
- 2010-03-29 RU RU2011137486/10A patent/RU2011137486A/ru not_active Application Discontinuation
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