JP2020514324A5 - - Google Patents

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Publication number
JP2020514324A5
JP2020514324A5 JP2019542200A JP2019542200A JP2020514324A5 JP 2020514324 A5 JP2020514324 A5 JP 2020514324A5 JP 2019542200 A JP2019542200 A JP 2019542200A JP 2019542200 A JP2019542200 A JP 2019542200A JP 2020514324 A5 JP2020514324 A5 JP 2020514324A5
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JP
Japan
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tumor
cells
oncolytic virus
infiltrating
cancer
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JP2019542200A
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English (en)
Japanese (ja)
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JP7724601B2 (ja
JP2020514324A (ja
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Priority claimed from PCT/US2018/016912 external-priority patent/WO2018145033A1/en
Publication of JP2020514324A publication Critical patent/JP2020514324A/ja
Publication of JP2020514324A5 publication Critical patent/JP2020514324A5/ja
Priority to JP2025037414A priority Critical patent/JP2025106256A/ja
Application granted granted Critical
Publication of JP7724601B2 publication Critical patent/JP7724601B2/ja
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JP2019542200A 2017-02-03 2018-02-05 腫瘍溶解性ウイルス療法 Active JP7724601B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025037414A JP2025106256A (ja) 2017-02-03 2025-03-10 腫瘍溶解性ウイルス療法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762454526P 2017-02-03 2017-02-03
US62/454,526 2017-02-03
PCT/US2018/016912 WO2018145033A1 (en) 2017-02-03 2018-02-05 Oncolytic virus therapy

Related Child Applications (1)

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JP2025037414A Division JP2025106256A (ja) 2017-02-03 2025-03-10 腫瘍溶解性ウイルス療法

Publications (3)

Publication Number Publication Date
JP2020514324A JP2020514324A (ja) 2020-05-21
JP2020514324A5 true JP2020514324A5 (https=) 2021-03-18
JP7724601B2 JP7724601B2 (ja) 2025-08-18

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ID=63041101

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JP2019542200A Active JP7724601B2 (ja) 2017-02-03 2018-02-05 腫瘍溶解性ウイルス療法
JP2025037414A Pending JP2025106256A (ja) 2017-02-03 2025-03-10 腫瘍溶解性ウイルス療法

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JP2025037414A Pending JP2025106256A (ja) 2017-02-03 2025-03-10 腫瘍溶解性ウイルス療法

Country Status (8)

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US (2) US12350303B2 (https=)
EP (1) EP3577132B1 (https=)
JP (2) JP7724601B2 (https=)
KR (2) KR102932184B1 (https=)
CN (2) CN118662538A (https=)
AU (3) AU2018215558B2 (https=)
CA (1) CA3052463A1 (https=)
WO (1) WO2018145033A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7724601B2 (ja) 2017-02-03 2025-08-18 ユニバーシティ オブ ピッツバーグ -オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 腫瘍溶解性ウイルス療法
EP3596108A4 (en) 2017-03-15 2020-12-23 Pandion Operations, Inc. TARGETED IMMUNOTOLERANCE
US10676516B2 (en) 2017-05-24 2020-06-09 Pandion Therapeutics, Inc. Targeted immunotolerance
US10174092B1 (en) 2017-12-06 2019-01-08 Pandion Therapeutics, Inc. IL-2 muteins
US10946068B2 (en) 2017-12-06 2021-03-16 Pandion Operations, Inc. IL-2 muteins and uses thereof
USRE50550E1 (en) 2017-12-06 2025-08-26 Pandion Operations, Inc. IL-2 muteins and uses thereof
BR112021023345A2 (pt) 2019-05-20 2022-02-01 Pandion Operations Inc Imunotolerância com alvo em madcam
EP4054612A4 (en) * 2019-11-07 2023-08-02 Baylor College of Medicine ONCOLYTIC VIROTHERAPY AND IMMUNOTHERAPY
EP4061417A4 (en) * 2019-11-20 2023-10-11 University of Pittsburgh - of the Commonwealth System of Higher Education VACCINIA VIRUSES AND METHOD FOR USING VACCINIA VIRUSES
EP4107187A4 (en) 2020-02-21 2024-07-03 Pandion Operations, Inc. TISSUE-TARGETED IMMUNOTOLERANCE WITH A CD39 EFFECTOR
CA3158133A1 (en) * 2020-04-28 2021-11-04 Lyell Immunopharma, Inc. Methods for culturing cells
CA3207359A1 (en) 2021-02-05 2022-08-11 Cecile Chartier-Courtaud Adjuvant therapy for cancer
CN117957323A (zh) * 2021-08-13 2024-04-30 深圳市华药康明生物药业有限责任公司 经修饰的痘苗病毒及其应用
CN113846068A (zh) * 2021-08-25 2021-12-28 居颂光 融合基因ril-7重组牛痘病毒及其在制备抗肿瘤药物中的应用
CN113832115A (zh) * 2021-08-25 2021-12-24 居颂光 融合基因ril-7联合ccl19重组溶瘤牛痘病毒及其在制备抗肿瘤药物中的应用
CN114058597A (zh) * 2021-10-28 2022-02-18 钟莉娉 生物制导溶瘤病毒制剂及应用
CN115948411A (zh) * 2022-11-23 2023-04-11 郑州大学 竞争性表达的il-12和il-23及其基因、重组载体和在制备治疗肿瘤药物中的应用

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5399363A (en) 1991-01-25 1995-03-21 Eastman Kodak Company Surface modified anticancer nanoparticles
US5543158A (en) 1993-07-23 1996-08-06 Massachusetts Institute Of Technology Biodegradable injectable nanoparticles
IE80468B1 (en) 1995-04-04 1998-07-29 Elan Corp Plc Controlled release biodegradable nanoparticles containing insulin
US6277368B1 (en) 1996-07-25 2001-08-21 The Regents Of The University Of California Cancer immunotherapy using autologous tumor cells combined with cells expressing a membrane cytokine
US5891432A (en) 1997-07-29 1999-04-06 The Immune Response Corporation Membrane-bound cytokine compositions comprising GM=CSF and methods of modulating an immune response using same
WO2000073479A1 (en) 1999-05-28 2000-12-07 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services A combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector
WO2003017944A2 (en) 2001-08-27 2003-03-06 Greenville Hospital System Gpi-anchored cytokines
US20030170238A1 (en) 2002-03-07 2003-09-11 Gruenberg Micheal L. Re-activated T-cells for adoptive immunotherapy
US9045727B2 (en) 2002-05-17 2015-06-02 Emory University Virus-like particles, methods of preparation, and immunogenic compositions
KR20120002613A (ko) 2002-08-12 2012-01-06 제네렉스, 인코포레이티드 폭스바이러스 및 암과 관련된 방법 및 조성물
KR101772375B1 (ko) 2005-09-07 2017-08-29 신라젠(주) Gm-csf를 발현하는 폭스바이러스를 사용한 전이성 및/또는 전신 파종성 암의 전신 치료법
KR20080084528A (ko) 2007-03-15 2008-09-19 제네렉스 바이오테라퓨틱스 인크. 종양살상형 백시니아 바이러스 암 치료
DE102008023820A1 (de) * 2008-05-08 2009-11-12 Aicuris Gmbh & Co. Kg Mittel zur Behandlung und/oder Prophylaxe einer Autoimmunerkrankung und zur Bildung von Regulatorischen T-Zellen
ES2733211T3 (es) 2011-04-15 2019-11-28 Genelux Corp Cepas clonales de virus vaccinia atenuados y métodos de uso de las mismas
US20150250837A1 (en) * 2012-09-20 2015-09-10 Morningside Technology Ventures Ltd. Oncolytic virus encoding pd-1 binding agents and uses of the same
WO2014138314A1 (en) * 2013-03-05 2014-09-12 Baylor College Of Medicine Oncolytic virus
RS65104B1 (sr) 2013-08-22 2024-02-29 Univ Pittsburgh Commonwealth Sys Higher Education Onkolitičke imunoterapije
BR112016009465A8 (pt) 2013-10-28 2018-01-30 Univ Pittsburgh Commonwealth Sys Higher Education vetor de hsv oncolítico.
EP3197911A4 (en) 2014-09-22 2018-06-20 Intrexon Corporation Improved therapeutic control of heterodimeric and single chain forms of interleukin-12
KR20170074235A (ko) 2014-10-31 2017-06-29 메사추세츠 인스티튜트 오브 테크놀로지 면역 세포로의 생체분자의 전달
AU2016232009B2 (en) * 2015-03-17 2021-07-15 Tilt Biotherapeutics Oy Oncolytic adenoviruses coding for bi-specific antibodies and methods and uses related thereto
HRP20200439T1 (hr) * 2015-04-30 2020-06-12 Psioxus Therapeutics Limited Onkolitički adenovirus koji kodira protein b7
EP3347473A4 (en) * 2015-09-09 2019-04-10 Tvax Biomedical I, LLC METHOD FOR COMBINING ADOPTIVE T CELL THERAPY WITH ONCOLYTIC VIRUS ATTACHMENT THERAPY
WO2017165464A1 (en) 2016-03-21 2017-09-28 Elstar Therapeutics, Inc. Multispecific and multifunctional molecules and uses thereof
SI3458083T1 (sl) 2016-05-18 2023-03-31 Modernatx, Inc. Polinukleotidi, ki kodirajo interlevkin-12 (IL12) in njihova uporaba
WO2017209053A1 (ja) 2016-05-30 2017-12-07 アステラス製薬株式会社 新規な遺伝子組換えワクシニアウイルス
EP3523323A4 (en) 2016-10-07 2020-06-17 Board of Regents, The University of Texas System T-CELLS WITH EXPRESSION OF MEMBRANE-ANCHORED IL-12 FOR THE TREATMENT OF CANCER
JP7724601B2 (ja) 2017-02-03 2025-08-18 ユニバーシティ オブ ピッツバーグ -オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 腫瘍溶解性ウイルス療法
JP7285220B2 (ja) 2017-05-18 2023-06-01 モデルナティエックス インコーポレイテッド 連結したインターロイキン-12(il12)ポリペプチドをコードするポリヌクレオチドを含む脂質ナノ粒子
EP3898997A4 (en) 2018-12-21 2022-11-16 Ottawa Hospital Research Institute MODIFIED ORTHOPOXVIRUS VECTORS
EP4061417A4 (en) * 2019-11-20 2023-10-11 University of Pittsburgh - of the Commonwealth System of Higher Education VACCINIA VIRUSES AND METHOD FOR USING VACCINIA VIRUSES

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