JP2020511410A5 - - Google Patents
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- Publication number
- JP2020511410A5 JP2020511410A5 JP2019531241A JP2019531241A JP2020511410A5 JP 2020511410 A5 JP2020511410 A5 JP 2020511410A5 JP 2019531241 A JP2019531241 A JP 2019531241A JP 2019531241 A JP2019531241 A JP 2019531241A JP 2020511410 A5 JP2020511410 A5 JP 2020511410A5
- Authority
- JP
- Japan
- Prior art keywords
- ethyl
- tetrahydropyran
- azepine
- pyrazolo
- spiro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16203335.1 | 2016-12-12 | ||
| EP16203335 | 2016-12-12 | ||
| PCT/EP2017/082424 WO2018108910A1 (en) | 2016-12-12 | 2017-12-12 | Substituted pyrazoloazepin-4-ones and their use as phosphodiesterase inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020511410A JP2020511410A (ja) | 2020-04-16 |
| JP2020511410A5 true JP2020511410A5 (https=) | 2021-01-21 |
| JP7008073B2 JP7008073B2 (ja) | 2022-01-25 |
Family
ID=57542834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019531241A Expired - Fee Related JP7008073B2 (ja) | 2016-12-12 | 2017-12-12 | 置換ピラゾロアゼピン－４－オンおよびそれらのホスホジエステラーゼ阻害剤としての使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US11065257B2 (https=) |
| EP (1) | EP3551632B1 (https=) |
| JP (1) | JP7008073B2 (https=) |
| CN (1) | CN110167944B (https=) |
| ES (1) | ES2981006T3 (https=) |
| RU (1) | RU2768746C2 (https=) |
| WO (1) | WO2018108910A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018234299A1 (en) | 2017-06-20 | 2018-12-27 | Leo Pharma A/S | Methods for the preparation of 1,3-benzodioxole heterocyclic compounds |
| ES2935615T3 (es) | 2017-12-15 | 2023-03-08 | Union Therapeutics As | Azetidina dihidrotienopiridinas sustituidas y su uso como inhibidores de la fosfodiesterasa |
| GB202306662D0 (en) | 2023-05-05 | 2023-06-21 | Union Therapeutics As | Dosage regimen |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2803299B1 (fr) * | 2000-01-05 | 2004-09-17 | Warner Lambert Co | NOUVELLES PYRAZOLO [4,3-e] DIAZEPINES SUBSTITUEES, COMPOSITIONS PHARMACEUTIQUES LES CONTENANT, UTILISATION A TITRE DE MEDICAMENT ET PROCEDES POUR LEUR PREPARATION |
| WO2004098520A2 (en) | 2003-05-01 | 2004-11-18 | Irm Llc | Compounds and compositions as protein kinase inhibitors |
| TW200745106A (en) | 2005-10-03 | 2007-12-16 | Astrazeneca Ab | Chemical compounds |
| WO2007115232A2 (en) | 2006-03-30 | 2007-10-11 | Chemocentryx, Inc. | Cxcr4 modulators |
| AU2007319786A1 (en) * | 2006-11-15 | 2008-05-22 | Vertex Pharmaceuticals Incorporated | Compounds useful as protein kinase inhibitors |
| RS53407B (sr) * | 2007-02-28 | 2014-10-31 | Leo Pharma A/S | Novi inhibitori fosfodiesteraze |
| GB0704652D0 (en) | 2007-03-09 | 2007-04-18 | Syngenta Participations Ag | Novel herbicides |
| JP2012532144A (ja) | 2009-07-01 | 2012-12-13 | アルバニー モレキュラー リサーチ， インコーポレイテッド | アジノン置換アゼピノ［ｂ］インドールおよびピリド−ピロロ−アゼピンｍｃｈ−１拮抗薬、ならびにその作製方法および使用 |
| ES2874632T3 (es) | 2016-12-12 | 2021-11-05 | Union Therapeutics As | Pirazoloazepin-8-onas sustituidas y su uso como inhibidores de la fosfodiesterasa |
| JP6850886B2 (ja) | 2016-12-12 | 2021-03-31 | レオ ファーマ アクティーゼルスカブ | 置換ピラゾロアゼピン−４−オンおよびそれらのホスホジエステラーゼ阻害剤としての使用 |
-
2017
- 2017-12-12 EP EP17811328.8A patent/EP3551632B1/en active Active
- 2017-12-12 JP JP2019531241A patent/JP7008073B2/ja not_active Expired - Fee Related
- 2017-12-12 CN CN201780076412.5A patent/CN110167944B/zh not_active Expired - Fee Related
- 2017-12-12 US US16/468,444 patent/US11065257B2/en active Active
- 2017-12-12 WO PCT/EP2017/082424 patent/WO2018108910A1/en not_active Ceased
- 2017-12-12 RU RU2019121694A patent/RU2768746C2/ru active
- 2017-12-12 ES ES17811328T patent/ES2981006T3/es active Active
-
2021
- 2021-06-10 US US17/303,955 patent/US20220362259A1/en not_active Abandoned
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