JP2020510704A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020510704A5 JP2020510704A5 JP2019571809A JP2019571809A JP2020510704A5 JP 2020510704 A5 JP2020510704 A5 JP 2020510704A5 JP 2019571809 A JP2019571809 A JP 2019571809A JP 2019571809 A JP2019571809 A JP 2019571809A JP 2020510704 A5 JP2020510704 A5 JP 2020510704A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- cancer
- composition
- composition according
- population
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023076631A JP2023103318A (ja) | 2017-03-15 | 2023-05-08 | 方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1704084.1 | 2017-03-15 | ||
| GBGB1704084.1A GB201704084D0 (en) | 2017-03-15 | 2017-03-15 | Method |
| GBGB1721603.7A GB201721603D0 (en) | 2017-12-21 | 2017-12-21 | Method |
| GB1721603.7 | 2017-12-21 | ||
| PCT/GB2018/050652 WO2018167486A1 (en) | 2017-03-15 | 2018-03-14 | Method |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023076631A Division JP2023103318A (ja) | 2017-03-15 | 2023-05-08 | 方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020510704A JP2020510704A (ja) | 2020-04-09 |
| JP2020510704A5 true JP2020510704A5 (https=) | 2021-04-22 |
| JP7277388B2 JP7277388B2 (ja) | 2023-05-18 |
Family
ID=61868533
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019571809A Active JP7277388B2 (ja) | 2017-03-15 | 2018-03-14 | 方法 |
| JP2023076631A Withdrawn JP2023103318A (ja) | 2017-03-15 | 2023-05-08 | 方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023076631A Withdrawn JP2023103318A (ja) | 2017-03-15 | 2023-05-08 | 方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11427645B2 (https=) |
| EP (1) | EP3595705A1 (https=) |
| JP (2) | JP7277388B2 (https=) |
| KR (2) | KR102609624B1 (https=) |
| CN (1) | CN110678197A (https=) |
| AU (2) | AU2018235130B2 (https=) |
| CA (1) | CA3056542A1 (https=) |
| WO (1) | WO2018167486A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11126040B2 (en) | 2012-09-30 | 2021-09-21 | Optica Amuka (A.A.) Ltd. | Electrically-tunable lenses and lens systems |
| AU2018250641B2 (en) | 2017-04-11 | 2025-03-13 | Inhibrx Biosciences, Inc. | Multispecific polypeptide constructs having constrained CD3 binding and methods of using the same |
| SG11202008399QA (en) | 2018-03-12 | 2020-09-29 | Genmab As | Antibodies |
| BR112020020604A2 (pt) | 2018-04-11 | 2021-01-12 | Inhibrx, Inc. | Construções de polipeptídeo multiespecífico tendo ligação restrita de cd3 e métodos e usos relacionados |
| WO2020023553A1 (en) | 2018-07-24 | 2020-01-30 | Inhibrx, Inc. | Multispecific polypeptide constructs containing a constrained cd3 binding domain and a receptor binding region and methods of using the same |
| WO2020028656A1 (en) * | 2018-08-01 | 2020-02-06 | Nantkwest, Inc. | A quadricistronic system comprising a homing receptor or a cytokine, and chimeric antigen receptor for genetic modification of immunotherapies |
| WO2020076992A1 (en) * | 2018-10-11 | 2020-04-16 | Inhibrx, Inc. | 5t4 single domain antibodies and therapeutic compositions thereof |
| GB201911958D0 (en) * | 2019-08-20 | 2019-10-02 | Adaptimmune Ltd | Methods of t cell production |
| US20220325336A1 (en) * | 2019-09-05 | 2022-10-13 | Bluebird Bio, Inc. | Transduction efficiency assay |
| WO2021072244A1 (en) * | 2019-10-11 | 2021-04-15 | Beth Israel Deaconess Medical Center, Inc. | Anti-tn antibodies and uses thereof |
| CN115380047A (zh) | 2020-01-29 | 2022-11-22 | 印希比股份有限公司 | Cd28单结构域抗体及其多价和多特异性构建体 |
| IL296103A (en) * | 2020-03-05 | 2022-11-01 | Neotx Therapeutics Ltd | Methods and compositions for treating cancer with immune cells |
| EP4337227A2 (en) | 2021-05-14 | 2024-03-20 | Kite Pharma, Inc. | Chimeric antigen receptor t cell therapy |
| KR20250090398A (ko) * | 2022-09-28 | 2025-06-19 | 스팍스 바이오사이언스 리미티드 | 백혈구 면역글로불린 유사 수용체 하위 패밀리 b 구성원 2(lilrb2)에 결합하는 항체 및 그 용도 |
| CN117069849B (zh) * | 2023-03-21 | 2024-02-23 | 武汉奥科博泰生物科技有限公司 | 识别nag的单克隆抗体及其应用 |
| CN117074674B (zh) * | 2023-03-23 | 2024-01-23 | 武汉勖瑞生物科技有限责任公司 | 检测N-乙酰-β-D氨基葡萄糖苷酶的胶体金试纸及其制备方法 |
| CN119074896A (zh) * | 2024-10-11 | 2024-12-06 | 内蒙古医科大学附属医院(内蒙古自治区心血管研究所) | Il-12在制备治疗t-all的药物中的用途 |
Family Cites Families (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4690915A (en) | 1985-08-08 | 1987-09-01 | The United States Of America As Represented By The Department Of Health And Human Services | Adoptive immunotherapy as a treatment modality in humans |
| US5869053A (en) | 1988-03-04 | 1999-02-09 | Cancer Research Campaign Technology, Ltd. | 5T4 antigen from human trophoblasts |
| WO1989007947A1 (en) | 1988-03-04 | 1989-09-08 | Cancer Research Campaign Technology Limited | Improvements relating to antigens |
| US6534055B1 (en) | 1988-11-23 | 2003-03-18 | Genetics Institute, Inc. | Methods for selectively stimulating proliferation of T cells |
| US6352694B1 (en) | 1994-06-03 | 2002-03-05 | Genetics Institute, Inc. | Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells |
| US5118672A (en) | 1989-07-10 | 1992-06-02 | University Of Georgia Research Foundation | 5'-diphosphohexose nucleoside pharmaceutical compositions |
| JPH0813274B2 (ja) | 1990-08-13 | 1996-02-14 | アイシス・ファーマシューティカルス・インコーポレーテッド | 遺伝子発現を検出及び変調する糖修飾されたオリゴヌクレオチド |
| US5199942A (en) | 1991-06-07 | 1993-04-06 | Immunex Corporation | Method for improving autologous transplantation |
| AU6852594A (en) | 1993-06-03 | 1995-01-03 | Therapeutic Antibodies Inc. | Production of antibody fragments |
| US7067318B2 (en) | 1995-06-07 | 2006-06-27 | The Regents Of The University Of Michigan | Methods for transfecting T cells |
| US6692964B1 (en) | 1995-05-04 | 2004-02-17 | The United States Of America As Represented By The Secretary Of The Navy | Methods for transfecting T cells |
| PL332875A1 (en) | 1996-10-17 | 1999-10-25 | Oxford Biomedica Ltd | Retroviral vectors |
| US6924123B2 (en) | 1996-10-29 | 2005-08-02 | Oxford Biomedica (Uk) Limited | Lentiviral LTR-deleted vector |
| EP1717248A1 (en) | 1997-06-04 | 2006-11-02 | Oxford Biomedica (UK) Limited | Tumor targeted vector |
| GB9711957D0 (en) | 1997-06-09 | 1997-08-06 | Isis Innovation | Methods and reagents for vaccination |
| ES2373406T3 (es) | 1997-12-22 | 2012-02-03 | Oxford Biomedica (Uk) Limited | Vectores basados en el virus de la anemia infecciosa equina (vaie). |
| GB2370571B (en) | 1998-11-18 | 2003-05-07 | Oxford Biomedica Ltd | A modified 5t4 antigen |
| EP1036091B2 (en) | 1998-11-18 | 2008-03-26 | Oxford Biomedica (UK) Limited | 5t4 tumour-associated antigen for use in tumour immunotherapy |
| GB2378704B (en) | 1998-11-18 | 2003-05-07 | Oxford Biomedica Ltd | Uses of 5t4 antigen |
| GB9825303D0 (en) * | 1998-11-18 | 1999-01-13 | Oxford Biomedica Ltd | Vector |
| GB9922361D0 (en) | 1999-09-21 | 1999-11-24 | Isis Innovation | Generating an immune response to an antigen |
| JP2003515323A (ja) * | 1999-11-18 | 2003-05-07 | オックスフォード バイオメディカ(ユーケイ)リミテッド | 抗 体 |
| US7572631B2 (en) | 2000-02-24 | 2009-08-11 | Invitrogen Corporation | Activation and expansion of T cells |
| CA2406864A1 (en) | 2000-02-24 | 2001-08-30 | Life Technologies Corporation | Simultaneous stimulation and concentration of cells |
| GB0009760D0 (en) | 2000-04-19 | 2000-06-07 | Oxford Biomedica Ltd | Method |
| WO2002038612A2 (en) | 2000-11-13 | 2002-05-16 | Oxford Biomedica (Uk) Limited | Canine and feline tumour-associated antigen 5t4 |
| CA2344208A1 (en) | 2001-04-30 | 2002-10-30 | Oxford Biomedica (Uk) Limited | Method |
| GB0126378D0 (en) * | 2001-11-02 | 2002-01-02 | Oxford Biomedica Ltd | Antigen |
| EP1504108B1 (en) | 2002-02-01 | 2013-04-17 | Oxford Biomedica (UK) Limited | Lentiviral vector |
| US20030170238A1 (en) | 2002-03-07 | 2003-09-11 | Gruenberg Micheal L. | Re-activated T-cells for adoptive immunotherapy |
| GB0215287D0 (en) * | 2002-07-02 | 2002-08-14 | Oxford Biomedica Ltd | 5T4 antigen expression |
| US7662625B2 (en) * | 2002-07-02 | 2010-02-16 | Cancer Research Technology Limited | Methods for detecting the differentiation status of cells using 5T4 antigen expression |
| DE60327795D1 (de) | 2002-11-09 | 2009-07-09 | Immunocore Ltd | T zell rezeptor "display" |
| PE20100251A1 (es) | 2004-09-10 | 2010-04-10 | Wyeth Corp | Anticuerpos anti-5t4 humanizados y conjugados anticuerpo anti-5t4/calicheamicina |
| EP2045268B1 (en) | 2005-05-13 | 2011-09-21 | Oxford BioMedica (UK) Limited | Mhc class I and II peptide antigens derived from tumour antigen 5t4 |
| GB0519303D0 (en) | 2005-09-21 | 2005-11-02 | Oxford Biomedica Ltd | Chemo-immunotherapy method |
| US7820174B2 (en) | 2006-02-24 | 2010-10-26 | The United States Of America As Represented By The Department Of Health And Human Services | T cell receptors and related materials and methods of use |
| MY148763A (en) * | 2006-03-10 | 2013-05-31 | Wyeth Corp | Anti-5t4 antibodies and uses thereof |
| AU2008206442B2 (en) | 2007-01-12 | 2012-10-18 | Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | gp100-specific T cell receptors and related materials and methods of use |
| WO2009070003A2 (en) | 2007-11-30 | 2009-06-04 | Mimos Berhad | An analog read out interface circuit for ion sensor |
| WO2009072003A2 (en) | 2007-12-07 | 2009-06-11 | Miltenyi Biotec Gmbh | Sample processing system and methods |
| EP2313784B1 (en) | 2008-07-15 | 2015-02-18 | Oxford BioMedica (UK) Limited | Immunotherapeutic method |
| EP2386062B1 (en) | 2009-01-09 | 2016-01-06 | Oxford Biomedica (UK) Ltd | Factors |
| WO2010088160A1 (en) | 2009-01-28 | 2010-08-05 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | T cell receptors and related materials and methods of use |
| ES2405605T3 (es) * | 2009-03-27 | 2013-05-31 | Wyeth Llc | Células iniciadoras de tumores y procedimientos de uso de las mismas |
| GB0918383D0 (en) | 2009-10-20 | 2009-12-02 | Cancer Rec Tech Ltd | Prognostic,screening and treatment methods and agents for treatment of metastasis and inflammation |
| CN103124740B (zh) | 2010-09-21 | 2015-09-02 | 美国卫生和人力服务部 | 抗-ssx-2t细胞受体和相关材料及使用方法 |
| GB201018480D0 (en) | 2010-11-02 | 2010-12-15 | Oxford Biomedica Ltd | Factors |
| DK2694111T3 (en) * | 2011-04-01 | 2016-10-10 | Wyeth Llc | Antibody pharmaceutical conjugates |
| GB201108879D0 (en) | 2011-05-25 | 2011-07-06 | Isis Innovation | Vector |
| WO2013068874A1 (en) | 2011-11-11 | 2013-05-16 | Pfizer Inc. | Antibody-drug conjugates |
| KR102437522B1 (ko) | 2012-05-25 | 2022-08-26 | 셀렉티스 | 면역요법을 위한 동종이형 및 면역억제제 저항성인 t 세포의 조작 방법 |
| CA2881981A1 (en) | 2012-08-20 | 2014-02-27 | Fred Hutchinson Cancer Research Center | Method and compositions for cellular immunotherapy |
| AU2013327136A1 (en) | 2012-10-02 | 2015-04-16 | Memorial Sloan-Kettering Cancer Center | Compositions and methods for immunotherapy |
| CA2927022C (en) * | 2013-10-11 | 2018-08-21 | Asana Biosciences, Llc | Protein-polymer-drug conjugates |
| GB201322798D0 (en) | 2013-12-20 | 2014-02-05 | Oxford Biomedica Ltd | Production system |
| WO2015155345A1 (en) * | 2014-04-11 | 2015-10-15 | Medimmune Limited | Antibodies and antibody-drug conjugates |
| WO2016022939A1 (en) * | 2014-08-08 | 2016-02-11 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Human monoclonal antibodies specific for 5t4 and methods of their use |
| ES2777305T5 (en) | 2014-09-04 | 2025-09-30 | Cellectis | Trophoblast glycoprotein (5t4, tpbg) specific chimeric antigen receptors for cancer immunotherapy |
| JP6949728B2 (ja) | 2015-05-29 | 2021-10-13 | ジュノー セラピューティクス インコーポレイテッド | 遺伝子操作された細胞における阻害相互作用を調節するための組成物および方法 |
| SG11202000503QA (en) * | 2017-07-20 | 2020-02-27 | Aptevo Res & Development Llc | Antigen binding proteins binding to 5t4 and 4-1bb and related compositions and methods |
-
2018
- 2018-03-14 CA CA3056542A patent/CA3056542A1/en active Pending
- 2018-03-14 JP JP2019571809A patent/JP7277388B2/ja active Active
- 2018-03-14 EP EP18715065.1A patent/EP3595705A1/en not_active Withdrawn
- 2018-03-14 KR KR1020197026693A patent/KR102609624B1/ko active Active
- 2018-03-14 CN CN201880018043.9A patent/CN110678197A/zh active Pending
- 2018-03-14 US US16/490,972 patent/US11427645B2/en active Active
- 2018-03-14 KR KR1020237040460A patent/KR20230166145A/ko not_active Withdrawn
- 2018-03-14 AU AU2018235130A patent/AU2018235130B2/en not_active Expired - Fee Related
- 2018-03-14 WO PCT/GB2018/050652 patent/WO2018167486A1/en not_active Ceased
-
2022
- 2022-07-27 US US17/815,531 patent/US20230084645A1/en not_active Abandoned
-
2023
- 2023-05-08 JP JP2023076631A patent/JP2023103318A/ja not_active Withdrawn
- 2023-11-29 AU AU2023274115A patent/AU2023274115A1/en not_active Withdrawn
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2020510704A5 (https=) | ||
| Zhang et al. | Autologous nanobody-derived fratricide-resistant CD7-CAR T-cell therapy for patients with relapsed and refractory T-cell acute lymphoblastic leukemia/lymphoma | |
| Alnefaie et al. | Chimeric antigen receptor T-cells: an overview of concepts, applications, limitations, and proposed solutions | |
| Frank et al. | Combining T-cell–specific activation and in vivo gene delivery through CD3-targeted lentiviral vectors | |
| Hou et al. | Navigating CAR-T cells through the solid-tumour microenvironment | |
| CN110475571B (zh) | 细胞免疫疗法前细胞毒性预调理的替代 | |
| Ottaviano et al. | Recent success and limitations of immune checkpoint inhibitors for cancer: a lesson from melanoma | |
| Fan et al. | Chimeric antigen receptors for adoptive T cell therapy in acute myeloid leukemia | |
| Abbott et al. | To go or not to go? Biological logic gating engineered T cells | |
| Antonia et al. | Immuno-oncology combinations: a review of clinical experience and future prospects | |
| Spear et al. | NKG2D CAR T‐cell therapy inhibits the growth of NKG2D ligand heterogeneous tumors | |
| Pabst et al. | Results from a phase I/II trial of cusatuzumab combined with azacitidine in patients with newly diagnosed acute myeloid leukemia who are ineligible for intensive chemotherapy | |
| Pocock et al. | Current and emerging therapeutic approaches for T‐cell acute lymphoblastic leukaemia | |
| Kim et al. | Current status and regulatory perspective of chimeric antigen receptor-modified T cell therapeutics | |
| Dinner et al. | Current therapy and novel agents for relapsed or refractory acute lymphoblastic leukemia | |
| Rosenzweig et al. | Preclinical data support leveraging CS1 chimeric antigen receptor T-cell therapy for systemic light chain amyloidosis | |
| Zamagni et al. | Anti-CD38 and anti-SLAMF7: the future of myeloma immunotherapy | |
| Savani et al. | New targets for CAR T therapy in hematologic malignancies | |
| Kassner et al. | Current landscape of CD3 bispecific antibodies in hematologic malignancies | |
| Pratap et al. | Finding new lanes: Chimeric antigen receptor (CAR) T‐cells for myeloid leukemia | |
| Mehta et al. | Monoclonal antibodies-based approaches in cancer immunotherapy | |
| Sun et al. | Macrophages: Targets for next-generation cancer immunotherapy | |
| CN115850484A (zh) | 一种靶向cd70的单链抗体及其应用 | |
| JPWO2020223702A5 (https=) | ||
| Baeuerle et al. | T cell engagers emerge as a compelling therapeutic modality |