JP2020509786A - 聴覚損失の治療のための遺伝子治療構成物および方法 - Google Patents

聴覚損失の治療のための遺伝子治療構成物および方法 Download PDF

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JP2020509786A
JP2020509786A JP2020500024A JP2020500024A JP2020509786A JP 2020509786 A JP2020509786 A JP 2020509786A JP 2020500024 A JP2020500024 A JP 2020500024A JP 2020500024 A JP2020500024 A JP 2020500024A JP 2020509786 A JP2020509786 A JP 2020509786A
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promoter
nucleic acid
hearing loss
tmprss3
seq
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JP2020509786A5 (enExample
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ヘンリッチ ステイカー
ヘンリッチ ステイカー
シュエ ゾン リュー
シュエ ゾン リュー
チャン−イー チェン
チャン−イー チェン
シーザー ジェイムズ アヤラ
シーザー ジェイムズ アヤラ
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レスキュー ヒヤリング インコーポレイテッド
レスキュー ヒヤリング インコーポレイテッド
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JP2020500024A 2017-03-17 2018-03-16 聴覚損失の治療のための遺伝子治療構成物および方法 Pending JP2020509786A (ja)

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Application Number Priority Date Filing Date Title
US201762472790P 2017-03-17 2017-03-17
US62/472,790 2017-03-17
US201762531522P 2017-07-12 2017-07-12
US62/531,522 2017-07-12
PCT/US2018/022873 WO2018170402A1 (en) 2017-03-17 2018-03-16 Gene therapy constructs and methods for treatment of hearing loss

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JP2020509786A true JP2020509786A (ja) 2020-04-02
JP2020509786A5 JP2020509786A5 (enExample) 2021-03-11

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JP2024500314A (ja) * 2020-12-03 2024-01-09 メディツィーニシェ・ホーホシューレ・ハノーファー 内耳遺伝子治療のためのレンチウイルスベクター技術

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US12391936B2 (en) 2017-03-17 2025-08-19 Rescue Hearing, Inc. Gene therapy systems and related methods for treatment of hearing loss
US12534739B2 (en) 2018-10-11 2026-01-27 Decibel Therapeutics, Inc. AAV1 vectors and uses thereof for treatment of otic indications
CN115820654A (zh) * 2019-08-30 2023-03-21 深圳华大基因股份有限公司 Loxhd1基因突变体及其应用
EP4081232A4 (en) * 2020-02-05 2024-02-28 Rescue Hearing Inc GENE THERAPY SYSTEMS AND ASSOCIATED METHODS FOR THE TREATMENT OF HEARING LOSS
CN113584082B (zh) * 2021-06-22 2023-07-25 复旦大学附属眼耳鼻喉科医院 CRISPR/Cas9基因编辑系统及其在制备治疗遗传性感音神经性聋的药物中的应用
CN113215248B (zh) * 2021-06-25 2022-04-22 中国人民解放军空军军医大学 一种感音神经性耳聋相关的myo15a基因突变检测试剂盒
CN121568725A (zh) * 2023-06-15 2026-02-24 里珍纳龙药品有限公司 用于听力病症的基因疗法
CN121674484A (zh) * 2025-11-14 2026-03-17 广州派真生物技术有限公司 一种高产细胞毒性基因的rAAV质粒系统及应用

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024500314A (ja) * 2020-12-03 2024-01-09 メディツィーニシェ・ホーホシューレ・ハノーファー 内耳遺伝子治療のためのレンチウイルスベクター技術

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