CA3054941A1 - Gene therapy constructs and methods for treatment of hearing loss - Google Patents
Gene therapy constructs and methods for treatment of hearing loss Download PDFInfo
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- CA3054941A1 CA3054941A1 CA3054941A CA3054941A CA3054941A1 CA 3054941 A1 CA3054941 A1 CA 3054941A1 CA 3054941 A CA3054941 A CA 3054941A CA 3054941 A CA3054941 A CA 3054941A CA 3054941 A1 CA3054941 A1 CA 3054941A1
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| IL295265A (en) * | 2020-02-05 | 2022-10-01 | Rescue Hearing Inc | Gene therapy systems and related methods for treatment of hearing loss |
| EP4008788A1 (en) * | 2020-12-03 | 2022-06-08 | Medizinische Hochschule Hannover | Lentiviral vector technology for inner ear gene therapy |
| CN113584082B (zh) * | 2021-06-22 | 2023-07-25 | 复旦大学附属眼耳鼻喉科医院 | CRISPR/Cas9基因编辑系统及其在制备治疗遗传性感音神经性聋的药物中的应用 |
| CN113215248B (zh) * | 2021-06-25 | 2022-04-22 | 中国人民解放军空军军医大学 | 一种感音神经性耳聋相关的myo15a基因突变检测试剂盒 |
| WO2024259309A1 (en) * | 2023-06-15 | 2024-12-19 | Regeneron Pharmaceuticals, Inc. | Gene therapy for hearing disorders |
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| JP6552511B2 (ja) | 2013-10-11 | 2019-07-31 | マサチューセッツ アイ アンド イヤー インファーマリー | 祖先ウイルス配列を予測する方法およびその使用 |
| WO2015175642A2 (en) * | 2014-05-13 | 2015-11-19 | Sangamo Biosciences, Inc. | Methods and compositions for prevention or treatment of a disease |
| WO2016069910A1 (en) | 2014-10-29 | 2016-05-06 | Massachusetts Eye And Ear Infirmary | Methods for efficient delivery of therapeutic molecules in vitro and in vivo |
| JP6990182B2 (ja) * | 2015-12-11 | 2022-02-15 | マサチューセッツ アイ アンド イヤー インファーマリー | 蝸牛および前庭細胞に核酸を送達するための材料および方法 |
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| CN112442528A (zh) * | 2019-08-30 | 2021-03-05 | 深圳华大基因股份有限公司 | Loxhd1基因突变体及其应用 |
| CN112442528B (zh) * | 2019-08-30 | 2022-08-12 | 深圳华大基因股份有限公司 | Loxhd1基因突变体及其应用 |
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