JP2020509031A5 - - Google Patents
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- Publication number
- JP2020509031A5 JP2020509031A5 JP2019547310A JP2019547310A JP2020509031A5 JP 2020509031 A5 JP2020509031 A5 JP 2020509031A5 JP 2019547310 A JP2019547310 A JP 2019547310A JP 2019547310 A JP2019547310 A JP 2019547310A JP 2020509031 A5 JP2020509031 A5 JP 2020509031A5
- Authority
- JP
- Japan
- Prior art keywords
- preparation according
- monoclonal antibody
- seq
- concentration
- cdr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022045862A JP7446356B2 (ja) | 2017-03-01 | 2022-03-22 | 抗ｒｓｖモノクローナル抗体製剤 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762465379P | 2017-03-01 | 2017-03-01 | |
| US62/465,379 | 2017-03-01 | ||
| PCT/US2018/020264 WO2018160722A1 (en) | 2017-03-01 | 2018-02-28 | Anti-rsv monoclonal antibody formulation |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022045862A Division JP7446356B2 (ja) | 2017-03-01 | 2022-03-22 | 抗ｒｓｖモノクローナル抗体製剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020509031A JP2020509031A (ja) | 2020-03-26 |
| JP2020509031A5 true JP2020509031A5 (enExample) | 2021-03-04 |
| JP7046088B2 JP7046088B2 (ja) | 2022-04-01 |
Family
ID=61903153
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019547310A Active JP7046088B2 (ja) | 2017-03-01 | 2018-02-28 | 抗ｒｓｖモノクローナル抗体製剤 |
| JP2022045862A Active JP7446356B2 (ja) | 2017-03-01 | 2022-03-22 | 抗ｒｓｖモノクローナル抗体製剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022045862A Active JP7446356B2 (ja) | 2017-03-01 | 2022-03-22 | 抗ｒｓｖモノクローナル抗体製剤 |
Country Status (24)
| Country | Link |
|---|---|
| US (4) | US10774133B2 (enExample) |
| EP (1) | EP3589648A4 (enExample) |
| JP (2) | JP7046088B2 (enExample) |
| KR (2) | KR102359181B1 (enExample) |
| CN (3) | CN110418803B (enExample) |
| AR (1) | AR111083A1 (enExample) |
| AU (2) | AU2018227502B2 (enExample) |
| BR (1) | BR112019017755A2 (enExample) |
| CA (1) | CA3051864A1 (enExample) |
| CL (1) | CL2019002478A1 (enExample) |
| CO (1) | CO2019009034A2 (enExample) |
| CR (1) | CR20190400A (enExample) |
| EA (1) | EA201991701A1 (enExample) |
| EC (1) | ECSP19062769A (enExample) |
| GB (1) | GB2564175B (enExample) |
| IL (2) | IL312499A (enExample) |
| MX (1) | MX2019010408A (enExample) |
| MY (1) | MY206022A (enExample) |
| PH (1) | PH12019501979A1 (enExample) |
| SG (1) | SG11201906853QA (enExample) |
| TW (3) | TWI911431B (enExample) |
| UA (1) | UA128450C2 (enExample) |
| WO (1) | WO2018160722A1 (enExample) |
| ZA (1) | ZA202006797B (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA117466C2 (uk) | 2012-12-13 | 2018-08-10 | Мерк Шарп Енд Доме Корп. | СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19 |
| RS60387B1 (sr) | 2014-01-15 | 2020-07-31 | Medimmune Llc | Rsv-specifična antitela i njihovi funkcionalni delovi |
| EP3383435A4 (en) * | 2015-11-30 | 2019-07-10 | Medimmune, LLC | OPTIMIZED RATES OF AMINO ACIDS AND SUGARS AS AMORPHOUS STABILIZING COMPOUNDS IN PHARMACEUTICAL COMPOSITIONS HAVING HIGH CONCENTRATIONS IN PROTEIN-BASED THERAPEUTICS |
| TWI911431B (zh) | 2017-03-01 | 2026-01-11 | 英商梅迪繆思有限公司 | 抗rsv單株抗體配製物 |
| JP2020509025A (ja) * | 2017-03-01 | 2020-03-26 | メドイミューン・リミテッドＭｅｄＩｍｍｕｎｅ Ｌｉｍｉｔｅｄ | モノクローナル抗体製剤 |
| JOP20190260A1 (ar) | 2017-05-02 | 2019-10-31 | Merck Sharp & Dohme | صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها |
| CN110913906A (zh) | 2017-05-02 | 2020-03-24 | 默沙东公司 | 抗lag3抗体的制剂和抗lag3抗体与抗pd-1抗体的共制剂 |
| MX2021004356A (es) | 2018-10-18 | 2021-05-31 | Merck Sharp & Dohme Llc | Formulaciones de anticuerpos anti-rsv y metodos de uso de las mismas. |
| MA54089A (fr) | 2018-10-31 | 2022-02-09 | Merck Sharp & Dohme | Anticorps anti-pd-1 humain et procédés d'utilisation associés |
| JP7503056B6 (ja) | 2018-11-07 | 2024-07-16 | メルク・シャープ・アンド・ドーム・エルエルシー | 抗ｌａｇ３抗体および抗ｐｄ－１抗体の共－製剤 |
| PE20212185A1 (es) | 2019-02-18 | 2021-11-11 | Lilly Co Eli | Formulacion de anticuerpos terapeuticos |
| EP3956351A1 (en) * | 2019-04-18 | 2022-02-23 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Biological and synthetic molecules inhibiting respiratory syncytial virus infection |
| US12024553B2 (en) | 2019-04-30 | 2024-07-02 | Medimmune Limited | Dosage regimens for and compositions including anti-RSV antibodies |
| WO2021195418A1 (en) | 2020-03-26 | 2021-09-30 | Vanderbilt University | Human monoclonal antibodies to severe acute respiratory syndrome coronavirus 2 (sars-cov-2) |
| IL300245A (en) * | 2020-07-31 | 2023-03-01 | Alamab Therapeutics Inc | Anti-connexin antibody formulations |
| CN115960214A (zh) * | 2021-10-12 | 2023-04-14 | 中国科学院分子细胞科学卓越创新中心 | 中和呼吸道合胞病毒的全人抗体的设计及应用 |
| TW202342510A (zh) | 2022-02-18 | 2023-11-01 | 英商Ｒｑ生物科技有限公司 | 抗體 |
| CN116987183B (zh) * | 2022-07-22 | 2024-10-15 | 北京智仁美博生物科技有限公司 | 抗呼吸道合胞病毒中和性抗体及其用途 |
| EP4588936A4 (en) * | 2022-12-08 | 2026-08-12 | Changchun Bcht Biotechnology Co | ANTIBODIES THAT BIND SPECIFICALLY TO VRS |
| CN121846262A (zh) * | 2026-01-05 | 2026-04-14 | 上海生物制品研究所有限责任公司 | 抗呼吸道合胞病毒单克隆抗体制剂 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5892019A (en) | 1987-07-15 | 1999-04-06 | The United States Of America, As Represented By The Department Of Health And Human Services | Production of a single-gene-encoded immunoglobulin |
| US5811524A (en) | 1995-06-07 | 1998-09-22 | Idec Pharmaceuticals Corporation | Neutralizing high affinity human monoclonal antibodies specific to RSV F-protein and methods for their manufacture and therapeutic use thereof |
| ES2148799T3 (es) | 1995-09-18 | 2000-10-16 | Intracel Corp | Anticuerpos monoclonales neutralizantes contra virus sincitial respiratorio. |
| GB0113179D0 (en) * | 2001-05-31 | 2001-07-25 | Novartis Ag | Organic compounds |
| US20030138417A1 (en) * | 2001-11-08 | 2003-07-24 | Kaisheva Elizabet A. | Stable liquid pharmaceutical formulation of IgG antibodies |
| US7132100B2 (en) * | 2002-06-14 | 2006-11-07 | Medimmune, Inc. | Stabilized liquid anti-RSV antibody formulations |
| US7425618B2 (en) * | 2002-06-14 | 2008-09-16 | Medimmune, Inc. | Stabilized anti-respiratory syncytial virus (RSV) antibody formulations |
| AU2013201261B2 (en) * | 2002-06-14 | 2016-06-23 | Medimmune, Llc | Stabilized liquid anti-RSV antibody formulations |
| PT1610820E (pt) * | 2003-04-04 | 2010-12-16 | Novartis Ag | Formulações de elevada concentração de anticorpos e proteínas |
| TW200636064A (en) | 2004-10-28 | 2006-10-16 | Centocor Inc | Anti-respiratory syncytial virus antibodies, antigens and uses thereof |
| AU2007223903B2 (en) * | 2006-03-06 | 2013-09-05 | Medimmune, Llc | Humanized anti-CD22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease |
| EP1997830A1 (en) | 2007-06-01 | 2008-12-03 | AIMM Therapeutics B.V. | RSV specific binding molecules and means for producing them |
| PE20091174A1 (es) * | 2007-12-27 | 2009-08-03 | Chugai Pharmaceutical Co Ltd | Formulacion liquida con contenido de alta concentracion de anticuerpo |
| BRPI0921424A2 (pt) | 2008-11-05 | 2016-01-05 | Merck Sharp & Dohme | vírus sincicial respiratório atenuado, composição imunogênica, molécula de ácido nucléico, célula recombinante, método para produzir uma resposta imune protetiva em um paciente, e, uso de uma quantidade imunologicamente eficaz de um ou mais dos seguintes: um rsv atenuado, uma população de rsv atenuado e uma composição imunogênica. |
| WO2011017070A1 (en) * | 2009-07-28 | 2011-02-10 | Merck Sharp & Dohme Corp. | Methods for producing high concentration lyophilized pharmaceutical formulations |
| US8568726B2 (en) | 2009-10-06 | 2013-10-29 | Medimmune Limited | RSV specific binding molecule |
| WO2011043643A1 (en) * | 2009-10-06 | 2011-04-14 | Medimmune Ltd | Rsv-specific binding molecule |
| CL2011003002A1 (es) | 2011-11-25 | 2012-05-25 | Univ Pontificia Catolica Chile | Anticuerpo monoclonal o un fragmento del mismo que se une a la proteina m2-1 del virus respiratorio sincicial (vrs) humano; secuencias nucleotidicas; composicion farmaceutica; metodo de diagnostico de infeccion producida por vrs; kit; y uso de dicho anticuerpo para preparar un medicamento. |
| JP6265970B2 (ja) * | 2012-03-26 | 2018-01-24 | サノフイ | 安定なＩｇＧ４に基づく結合剤の製剤 |
| US20140004131A1 (en) | 2012-05-04 | 2014-01-02 | Novartis Ag | Antibody formulation |
| US8883979B2 (en) * | 2012-08-31 | 2014-11-11 | Bayer Healthcare Llc | Anti-prolactin receptor antibody formulations |
| RS60056B1 (sr) | 2013-02-01 | 2020-04-30 | Medimmune Llc | Epitopi f proteina respiratornog sincicijalnog virusa |
| RS60387B1 (sr) | 2014-01-15 | 2020-07-31 | Medimmune Llc | Rsv-specifična antitela i njihovi funkcionalni delovi |
| US20170247460A1 (en) * | 2014-10-18 | 2017-08-31 | Pfizer Inc. | Anti-il-7r antibody compositions |
| CN107847580B (zh) | 2015-07-07 | 2022-08-12 | 扬森疫苗与预防公司 | 针对rsv的疫苗 |
| JO3555B1 (ar) | 2015-10-29 | 2020-07-05 | Merck Sharp & Dohme | جسم مضاد يبطل فعالية فيروس الالتهاب الرئوي البشري |
| JP2020509025A (ja) * | 2017-03-01 | 2020-03-26 | メドイミューン・リミテッドＭｅｄＩｍｍｕｎｅ Ｌｉｍｉｔｅｄ | モノクローナル抗体製剤 |
| TWI911431B (zh) * | 2017-03-01 | 2026-01-11 | 英商梅迪繆思有限公司 | 抗rsv單株抗體配製物 |
| US12024553B2 (en) * | 2019-04-30 | 2024-07-02 | Medimmune Limited | Dosage regimens for and compositions including anti-RSV antibodies |
-
2018
- 2018-02-13 TW TW111113045A patent/TWI911431B/zh active
- 2018-02-13 TW TW114151960A patent/TWI926892B/zh active
- 2018-02-13 TW TW107105368A patent/TWI761453B/zh active
- 2018-02-23 GB GB1802974.4A patent/GB2564175B/en active Active
- 2018-02-26 AR ARP180100448A patent/AR111083A1/es not_active Application Discontinuation
- 2018-02-28 CR CR20190400A patent/CR20190400A/es unknown
- 2018-02-28 MX MX2019010408A patent/MX2019010408A/es unknown
- 2018-02-28 SG SG11201906853QA patent/SG11201906853QA/en unknown
- 2018-02-28 IL IL312499A patent/IL312499A/en unknown
- 2018-02-28 CA CA3051864A patent/CA3051864A1/en active Pending
- 2018-02-28 EP EP18761614.9A patent/EP3589648A4/en active Pending
- 2018-02-28 KR KR1020197025250A patent/KR102359181B1/ko active Active
- 2018-02-28 EA EA201991701A patent/EA201991701A1/ru unknown
- 2018-02-28 CN CN201880014929.6A patent/CN110418803B/zh active Active
- 2018-02-28 WO PCT/US2018/020264 patent/WO2018160722A1/en not_active Ceased
- 2018-02-28 AU AU2018227502A patent/AU2018227502B2/en active Active
- 2018-02-28 IL IL268202A patent/IL268202B2/en unknown
- 2018-02-28 KR KR1020227003517A patent/KR102668158B1/ko active Active
- 2018-02-28 UA UAA201908966A patent/UA128450C2/uk unknown
- 2018-02-28 CN CN202210988780.XA patent/CN116059343B/zh active Active
- 2018-02-28 BR BR112019017755-8A patent/BR112019017755A2/pt not_active Application Discontinuation
- 2018-02-28 MY MYPI2019004962A patent/MY206022A/en unknown
- 2018-02-28 JP JP2019547310A patent/JP7046088B2/ja active Active
- 2018-02-28 CN CN202410036839.4A patent/CN117982637A/zh active Pending
- 2018-02-28 US US15/907,876 patent/US10774133B2/en active Active
-
2019
- 2019-08-21 CO CONC2019/0009034A patent/CO2019009034A2/es unknown
- 2019-08-28 CL CL2019002478A patent/CL2019002478A1/es unknown
- 2019-08-29 EC ECSENADI201962769A patent/ECSP19062769A/es unknown
- 2019-08-29 PH PH12019501979A patent/PH12019501979A1/en unknown
-
2020
- 2020-07-13 US US16/927,169 patent/US11667698B2/en active Active
- 2020-10-30 ZA ZA2020/06797A patent/ZA202006797B/en unknown
-
2021
- 2021-06-18 US US17/351,348 patent/US11286294B2/en active Active
-
2022
- 2022-03-22 JP JP2022045862A patent/JP7446356B2/ja active Active
- 2022-11-04 AU AU2022263564A patent/AU2022263564B2/en active Active
-
2023
- 2023-04-28 US US18/309,475 patent/US20230399383A1/en not_active Abandoned
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