JP2020508993A5 - - Google Patents
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- Publication number
- JP2020508993A5 JP2020508993A5 JP2019544856A JP2019544856A JP2020508993A5 JP 2020508993 A5 JP2020508993 A5 JP 2020508993A5 JP 2019544856 A JP2019544856 A JP 2019544856A JP 2019544856 A JP2019544856 A JP 2019544856A JP 2020508993 A5 JP2020508993 A5 JP 2020508993A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- solvent
- composition according
- alcohol
- ethoxyethoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims description 45
- 239000002904 solvent Substances 0.000 claims description 44
- XXJWXESWEXIICW-UHFFFAOYSA-N diethylene glycol monoethyl ether Chemical compound CCOCCOCCO XXJWXESWEXIICW-UHFFFAOYSA-N 0.000 claims description 23
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 20
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims description 18
- 235000019441 ethanol Nutrition 0.000 claims description 14
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 12
- 206010000496 acne Diseases 0.000 claims description 12
- 229920001451 polypropylene glycol Polymers 0.000 claims description 12
- 229920001223 polyethylene glycol Polymers 0.000 claims description 10
- 125000000217 alkyl group Chemical group 0.000 claims description 8
- 239000012049 topical pharmaceutical composition Substances 0.000 claims description 8
- DNIAPMSPPWPWGF-GSVOUGTGSA-N (R)-(-)-Propylene glycol Chemical compound C[C@@H](O)CO DNIAPMSPPWPWGF-GSVOUGTGSA-N 0.000 claims description 6
- 208000002874 Acne Vulgaris Diseases 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 6
- 230000002265 prevention Effects 0.000 claims description 6
- WNWHHMBRJJOGFJ-UHFFFAOYSA-N 16-methylheptadecan-1-ol Chemical compound CC(C)CCCCCCCCCCCCCCCO WNWHHMBRJJOGFJ-UHFFFAOYSA-N 0.000 claims description 4
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 4
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 claims description 4
- 150000001298 alcohols Chemical class 0.000 claims description 4
- 229910052799 carbon Inorganic materials 0.000 claims description 4
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical group [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 claims description 4
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 claims description 4
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 claims description 4
- 239000013557 residual solvent Substances 0.000 claims description 4
- 239000000203 mixture Substances 0.000 claims description 3
- ALSTYHKOOCGGFT-KTKRTIGZSA-N (9Z)-octadecen-1-ol Chemical compound CCCCCCCC\C=C/CCCCCCCCO ALSTYHKOOCGGFT-KTKRTIGZSA-N 0.000 claims description 2
- XULHFMYCBKQGEE-UHFFFAOYSA-N 2-hexyl-1-Decanol Chemical compound CCCCCCCCC(CO)CCCCCC XULHFMYCBKQGEE-UHFFFAOYSA-N 0.000 claims description 2
- 239000002202 Polyethylene glycol Substances 0.000 claims description 2
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical group [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims description 2
- 239000008186 active pharmaceutical agent Substances 0.000 claims description 2
- 239000002671 adjuvant Substances 0.000 claims description 2
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 claims description 2
- 239000003937 drug carrier Substances 0.000 claims description 2
- 150000002170 ethers Chemical class 0.000 claims description 2
- 150000002191 fatty alcohols Chemical class 0.000 claims description 2
- UQEAIHBTYFGYIE-UHFFFAOYSA-N hexamethyldisiloxane Chemical compound C[Si](C)(C)O[Si](C)(C)C UQEAIHBTYFGYIE-UHFFFAOYSA-N 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 claims description 2
- CXQXSVUQTKDNFP-UHFFFAOYSA-N octamethyltrisiloxane Chemical compound C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C CXQXSVUQTKDNFP-UHFFFAOYSA-N 0.000 claims description 2
- 229940055577 oleyl alcohol Drugs 0.000 claims description 2
- XMLQWXUVTXCDDL-UHFFFAOYSA-N oleyl alcohol Natural products CCCCCCC=CCCCCCCCCCCO XMLQWXUVTXCDDL-UHFFFAOYSA-N 0.000 claims description 2
- 230000000699 topical effect Effects 0.000 claims description 2
- 239000003981 vehicle Substances 0.000 claims description 2
- 230000035876 healing Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762459312P | 2017-02-15 | 2017-02-15 | |
| AU2017900498A AU2017900498A0 (en) | 2017-02-15 | Compositions for Treating Acne | |
| US62/459,312 | 2017-02-15 | ||
| AU2017900498 | 2017-02-15 | ||
| PCT/AU2018/050117 WO2018148795A1 (en) | 2017-02-15 | 2018-02-14 | Compositions for treating acne |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020508993A JP2020508993A (ja) | 2020-03-26 |
| JP2020508993A5 true JP2020508993A5 (enExample) | 2021-01-14 |
Family
ID=67766788
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019544856A Pending JP2020508993A (ja) | 2017-02-15 | 2018-02-14 | ざ瘡を処置するための組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20200022927A1 (enExample) |
| EP (1) | EP3582763A4 (enExample) |
| JP (1) | JP2020508993A (enExample) |
| CN (1) | CN110430872A (enExample) |
| AU (1) | AU2018221889A1 (enExample) |
| BR (1) | BR112019017045A2 (enExample) |
| CA (1) | CA3053507A1 (enExample) |
| IL (1) | IL268715A (enExample) |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2338124C (en) * | 2001-02-26 | 2010-08-03 | Valerie Dumont Dicianna | Self-tanning composition in sheeted substrate |
| FR2867682B1 (fr) * | 2004-03-22 | 2009-06-05 | Galderma Res & Dev | Composition pharmaceutique anhydre associant un agent silicone et un principe actif solubilise. |
| WO2009090495A2 (en) * | 2007-12-07 | 2009-07-23 | Foamix Ltd. | Oil and liquid silicone foamable carriers and formulations |
| US20100261795A1 (en) * | 2009-04-08 | 2010-10-14 | Pierre Fabre Dermocosmetique Usa | Antiacneic compositions |
| JP5964322B2 (ja) * | 2011-01-13 | 2016-08-03 | キュー エル ティー インク．ＱＬＴ Ｉｎｃ． | 光増感剤の局所送達用医薬組成物及びその使用 |
| US20150141389A1 (en) * | 2012-04-27 | 2015-05-21 | Dow Corning Corporation | Topical Formulation Compositions Containing Silicone Based Excipients To Deliver Actives To A Substrate |
| CA2888060C (en) * | 2012-10-24 | 2019-02-26 | John E. Kulesza | Low toxicity topical active agent delivery system |
| WO2014081674A1 (en) * | 2012-11-20 | 2014-05-30 | Allergan, Inc. | Topical dapsone and dapsone/adapalene compositions and methods for use thereof |
| WO2014116653A1 (en) * | 2013-01-22 | 2014-07-31 | Coty Inc. | Topical formulations and methods for the use thereof |
| EP3065702B1 (en) * | 2013-10-31 | 2023-06-07 | Sun Pharmaceutical Industries Ltd | Topical pharmaceutical composition of acitretin |
-
2018
- 2018-02-14 US US16/486,323 patent/US20200022927A1/en not_active Abandoned
- 2018-02-14 CA CA3053507A patent/CA3053507A1/en active Pending
- 2018-02-14 JP JP2019544856A patent/JP2020508993A/ja active Pending
- 2018-02-14 CN CN201880019063.8A patent/CN110430872A/zh active Pending
- 2018-02-14 AU AU2018221889A patent/AU2018221889A1/en not_active Abandoned
- 2018-02-14 EP EP18754614.8A patent/EP3582763A4/en not_active Withdrawn
- 2018-02-14 BR BR112019017045A patent/BR112019017045A2/pt not_active IP Right Cessation
-
2019
- 2019-08-14 IL IL26871519A patent/IL268715A/en unknown
-
2022
- 2022-07-01 US US17/856,781 patent/US20220331269A1/en not_active Abandoned
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