JP2020507346A5 - - Google Patents
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- Publication number
- JP2020507346A5 JP2020507346A5 JP2019565061A JP2019565061A JP2020507346A5 JP 2020507346 A5 JP2020507346 A5 JP 2020507346A5 JP 2019565061 A JP2019565061 A JP 2019565061A JP 2019565061 A JP2019565061 A JP 2019565061A JP 2020507346 A5 JP2020507346 A5 JP 2020507346A5
- Authority
- JP
- Japan
- Prior art keywords
- small organic
- organic molecule
- molecule
- identifier tag
- dna identifier
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 16
- 229920001400 block copolymer Polymers 0.000 claims 7
- 150000001875 compounds Chemical class 0.000 claims 4
- 239000000693 micelle Substances 0.000 claims 4
- 239000011541 reaction mixture Substances 0.000 claims 4
- 239000003054 catalyst Substances 0.000 claims 3
- 238000006243 chemical reaction Methods 0.000 claims 3
- 230000002209 hydrophobic effect Effects 0.000 claims 3
- 239000003125 aqueous solvent Substances 0.000 claims 2
- 125000003118 aryl group Chemical group 0.000 claims 2
- 125000005842 heteroatom Chemical group 0.000 claims 2
- 125000005647 linker group Chemical group 0.000 claims 2
- 238000005192 partition Methods 0.000 claims 2
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 claims 1
- 238000007341 Heck reaction Methods 0.000 claims 1
- 229920002125 Sokalan® Polymers 0.000 claims 1
- 238000006069 Suzuki reaction reaction Methods 0.000 claims 1
- 230000002378 acidificating effect Effects 0.000 claims 1
- 125000005396 acrylic acid ester group Chemical group 0.000 claims 1
- 238000006555 catalytic reaction Methods 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 229920002401 polyacrylamide Polymers 0.000 claims 1
- 238000000746 purification Methods 0.000 claims 1
- 230000002194 synthesizing effect Effects 0.000 claims 1
- 229910052723 transition metal Inorganic materials 0.000 claims 1
- 150000003624 transition metals Chemical group 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17156047.7 | 2017-02-14 | ||
| EP17156047.7A EP3360962A1 (en) | 2017-02-14 | 2017-02-14 | Synthesis of dna-encoded libraries by micellar catalysis |
| PCT/EP2018/053650 WO2018149863A1 (en) | 2017-02-14 | 2018-02-14 | Method for the synthesis of dna conjugates by micellar catalysis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020507346A JP2020507346A (ja) | 2020-03-12 |
| JP2020507346A5 true JP2020507346A5 (OSRAM) | 2021-02-12 |
| JP7094029B2 JP7094029B2 (ja) | 2022-07-01 |
Family
ID=58056978
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019565061A Active JP7094029B2 (ja) | 2017-02-14 | 2018-02-14 | ミセル触媒作用によってｄｎａコンジュゲートを合成する方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11407993B2 (OSRAM) |
| EP (2) | EP3360962A1 (OSRAM) |
| JP (1) | JP7094029B2 (OSRAM) |
| CN (1) | CN110300804B (OSRAM) |
| WO (1) | WO2018149863A1 (OSRAM) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4038555A4 (en) * | 2019-10-03 | 2023-10-25 | Atomwise Inc. | SYSTEMS AND METHODS FOR IN SILICO COMPOUND SCREENING |
| CN112831843A (zh) * | 2019-11-22 | 2021-05-25 | 成都先导药物开发股份有限公司 | 一种一锅法On-DNA铃木反应方法 |
| GB202103343D0 (en) | 2021-03-11 | 2021-04-28 | Univ Newcastle | Micellar catalysis |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5529525A (en) * | 1978-08-21 | 1980-03-01 | Hidetoshi Tsuchida | Metal complex of hydrophilic and hydrophobic block copolymer |
| JPS55144048A (en) * | 1979-04-27 | 1980-11-10 | Hidetoshi Tsuchida | Coordination high polymeric metal complex composition for adsorption-desorption of oxygen |
| JP2002345460A (ja) | 2001-03-23 | 2002-12-03 | Fuji Photo Film Co Ltd | 修飾触媒及びそれを用いた反応器並びに防汚樹脂組成物 |
| GB0307428D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Compartmentalised combinatorial chemistry |
| UA95604C2 (ru) | 2005-02-18 | 2011-08-25 | Сьёрфейс Лоджикс, Инк. | Способ регулирования фармакокинетического и/или фармакодинамического свойства соединения |
| US20090298676A1 (en) * | 2005-10-26 | 2009-12-03 | Michael Meier | Unimolocular Micelles Containing Metal Nanoparticles and their Use as Catalyst for Synthesis of Carbon-Carbon-Bonds |
| EP1972349A1 (en) * | 2007-03-21 | 2008-09-24 | Biocompatibles UK Limited | GLP-1 fusion peptides conjugated to polymer(s), their production and use |
| US20110281934A1 (en) * | 2008-11-06 | 2011-11-17 | Phaserx, Inc. | Micelles of hydrophilically shielded membrane-destabilizing copolymers |
| US8741558B2 (en) * | 2009-02-04 | 2014-06-03 | Wake Forest University | Compositions, methods, and kits for identifying candidate molecules from encoded chemical libraries |
| WO2010118471A1 (en) * | 2009-04-17 | 2010-10-21 | The University Of Queensland | Reactor and method for performing a chemical reaction |
| IN2014CN02574A (OSRAM) * | 2011-09-07 | 2015-06-26 | Chem Inc X | |
| EP2914745B1 (en) | 2012-11-05 | 2017-09-06 | Rubicon Genomics, Inc. | Barcoding nucleic acids |
| EP3184674A1 (en) | 2015-12-23 | 2017-06-28 | Technische Universität Dortmund | Dna-encoded chemical library, use thereof and method to synthesize the library |
-
2017
- 2017-02-14 EP EP17156047.7A patent/EP3360962A1/en not_active Withdrawn
-
2018
- 2018-02-14 JP JP2019565061A patent/JP7094029B2/ja active Active
- 2018-02-14 WO PCT/EP2018/053650 patent/WO2018149863A1/en not_active Ceased
- 2018-02-14 EP EP18703801.3A patent/EP3583211B1/en active Active
- 2018-02-14 US US16/485,458 patent/US11407993B2/en active Active
- 2018-02-14 CN CN201880012015.6A patent/CN110300804B/zh active Active
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