JP2020503252A5 - - Google Patents

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Publication number
JP2020503252A5
JP2020503252A5 JP2019521034A JP2019521034A JP2020503252A5 JP 2020503252 A5 JP2020503252 A5 JP 2020503252A5 JP 2019521034 A JP2019521034 A JP 2019521034A JP 2019521034 A JP2019521034 A JP 2019521034A JP 2020503252 A5 JP2020503252 A5 JP 2020503252A5
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JP
Japan
Prior art keywords
cancer
pharmaceutical composition
clec
composition according
human
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JP2019521034A
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English (en)
Japanese (ja)
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JP2020503252A (ja
JP7032396B2 (ja
JP7032396B6 (ja
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Priority claimed from PCT/EP2017/076911 external-priority patent/WO2018073440A1/en
Publication of JP2020503252A publication Critical patent/JP2020503252A/ja
Publication of JP2020503252A5 publication Critical patent/JP2020503252A5/ja
Priority to JP2022025697A priority Critical patent/JP7404418B6/ja
Publication of JP7032396B2 publication Critical patent/JP7032396B2/ja
Application granted granted Critical
Publication of JP7032396B6 publication Critical patent/JP7032396B6/ja
Active legal-status Critical Current
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JP2019521034A 2016-10-21 2017-10-20 T細胞応答を促進するための方法 Active JP7032396B6 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022025697A JP7404418B6 (ja) 2016-10-21 2022-02-22 T細胞応答を促進するための方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP16306381 2016-10-21
EP16306381.1 2016-10-21
EP17305988.2 2017-07-24
EP17305988 2017-07-24
PCT/EP2017/076911 WO2018073440A1 (en) 2016-10-21 2017-10-20 Methods for promoting t cells response

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022025697A Division JP7404418B6 (ja) 2016-10-21 2022-02-22 T細胞応答を促進するための方法

Publications (4)

Publication Number Publication Date
JP2020503252A JP2020503252A (ja) 2020-01-30
JP2020503252A5 true JP2020503252A5 (enExample) 2020-12-03
JP7032396B2 JP7032396B2 (ja) 2022-03-08
JP7032396B6 JP7032396B6 (ja) 2022-03-22

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ID=60293924

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019521034A Active JP7032396B6 (ja) 2016-10-21 2017-10-20 T細胞応答を促進するための方法
JP2022025697A Active JP7404418B6 (ja) 2016-10-21 2022-02-22 T細胞応答を促進するための方法

Family Applications After (1)

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JP2022025697A Active JP7404418B6 (ja) 2016-10-21 2022-02-22 T細胞応答を促進するための方法

Country Status (21)

Country Link
US (3) US11365257B2 (enExample)
EP (2) EP3529262B1 (enExample)
JP (2) JP7032396B6 (enExample)
KR (1) KR102646708B1 (enExample)
CN (1) CN110291102A (enExample)
AU (1) AU2017345286B2 (enExample)
CA (1) CA3039348C (enExample)
CY (1) CY1124584T1 (enExample)
DK (1) DK3529262T3 (enExample)
ES (2) ES2883678T3 (enExample)
HR (1) HRP20211544T1 (enExample)
HU (1) HUE056016T2 (enExample)
IL (1) IL266111B (enExample)
LT (1) LT3529262T (enExample)
MA (1) MA46570B1 (enExample)
MD (1) MD3529262T2 (enExample)
PL (1) PL3529262T3 (enExample)
RS (1) RS62463B1 (enExample)
SI (1) SI3529262T1 (enExample)
SM (1) SMT202100555T1 (enExample)
WO (1) WO2018073440A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3529262T3 (pl) * 2016-10-21 2021-12-27 Inserm - Institut National De La Santé Et De La Recherche Médicale Sposoby wspomagania odpowiedzi limfocytów t
IL268895B2 (en) 2017-02-28 2025-05-01 Vor Biopharma Inc Compositions and methods for inhibition of lineage specific proteins
WO2020047164A1 (en) 2018-08-28 2020-03-05 Vor Biopharma, Inc Genetically engineered hematopoietic stem cells and uses thereof
CA3159155A1 (en) * 2019-12-05 2021-06-10 Ose Immunotherapeutics Anti-clec-1a antibodies and antigen-binding fragment thereof
CN113156140A (zh) * 2021-03-05 2021-07-23 青岛大学附属医院 C型凝集素样受体-1作为真菌性角膜炎的治疗标志物的应用
US12448454B2 (en) 2021-06-08 2025-10-21 Inserm (Institut National De La Sante Et De La Recherche Medicale) Humanized anti-CLEC-1A antibodies and antigen-binding fragments thereof
CN118510534A (zh) 2021-11-09 2024-08-16 Ose免疫疗法 Clec-1配体的识别及其用途
WO2024028347A1 (en) 2022-08-01 2024-02-08 Ose Immunotherapeutics Heterodimeric fc-clec-1 fusion molecule and uses thereof
WO2025032213A1 (en) 2023-08-10 2025-02-13 Ose Immunotherapeutics Identification of hla-dra as a ligand of clec-1 and uses thereof

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US5567610A (en) 1986-09-04 1996-10-22 Bioinvent International Ab Method of producing human monoclonal antibodies and kit therefor
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
US5175384A (en) 1988-12-05 1992-12-29 Genpharm International Transgenic mice depleted in mature t-cells and methods for making transgenic mice
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5859205A (en) 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
US6150584A (en) 1990-01-12 2000-11-21 Abgenix, Inc. Human antibodies derived from immunized xenomice
US5229275A (en) 1990-04-26 1993-07-20 Akzo N.V. In-vitro method for producing antigen-specific human monoclonal antibodies
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
US5565332A (en) 1991-09-23 1996-10-15 Medical Research Council Production of chimeric antibodies - a combinatorial approach
US5573905A (en) 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
PT1621554E (pt) 1992-08-21 2009-07-13 Univ Bruxelles Imunoglobtainas desprovidas de cadeias leves
US5618829A (en) 1993-01-28 1997-04-08 Mitsubishi Chemical Corporation Tyrosine kinase inhibitors and benzoylacrylamide derivatives
WO1995002420A2 (en) 1993-07-15 1995-01-26 Cancer Research Campaign Technology Ltd. Prodrugs of protein tyrosine kinase inhibitors
EP0690452A3 (en) 1994-06-28 1999-01-07 Advanced Micro Devices, Inc. Electrically erasable memory and method of erasure
US5804396A (en) 1994-10-12 1998-09-08 Sugen, Inc. Assay for agents active in proliferative disorders
EP0739981A1 (en) 1995-04-25 1996-10-30 Vrije Universiteit Brussel Variable fragments of immunoglobulins - use for therapeutic or veterinary purposes
US5639757A (en) 1995-05-23 1997-06-17 Pfizer Inc. 4-aminopyrrolo[2,3-d]pyrimidines as tyrosine kinase inhibitors
JP3370340B2 (ja) 1996-04-12 2003-01-27 ワーナー―ランバート・コンパニー チロシンキナーゼの不可逆的阻害剤
ZA986732B (en) 1997-07-29 1999-02-02 Warner Lambert Co Irreversible inhibitiors of tyrosine kinases
US6100254A (en) 1997-10-10 2000-08-08 Board Of Regents, The University Of Texas System Inhibitors of protein tyrosine kinases
US6740665B1 (en) 1999-02-10 2004-05-25 Ramachandran Murali Tyrosine kinase inhibitors and methods of using the same
US6245759B1 (en) 1999-03-11 2001-06-12 Merck & Co., Inc. Tyrosine kinase inhibitors
AU5636900A (en) 1999-06-30 2001-01-31 Merck & Co., Inc. Src kinase inhibitor compounds
WO2001000207A1 (en) 1999-06-30 2001-01-04 Merck & Co., Inc. Src kinase inhibitor compounds
JP2003503354A (ja) 1999-06-30 2003-01-28 メルク エンド カムパニー インコーポレーテッド Srcキナーゼ阻害剤化合物
BR0013899A (pt) 1999-09-10 2003-07-08 Merck & Co Inc Composto, composição farmacêutica, processos de tratamento ou prevenção de câncer, de uma doença em que a angiogênese esteja implicada, da vascularização retinal, da retinopatia diabética, da degeneração macular relacionada a idade, de doenças inflamatórias, de uma doença ou condições dependentes da tirosina quinase, de patologias associadas com ossos, e, processos para produzir uma composição farmacêutica, e de reduzir ou prevenir dano tecidual em seguida a um evento isquêmico cerebral
KR100681724B1 (ko) 1999-10-19 2007-02-28 머크 앤드 캄파니 인코포레이티드 티로신 키나제 억제제 및 이를 포함하는 약제학적 조성물
JP2003512353A (ja) 1999-10-19 2003-04-02 メルク エンド カムパニー インコーポレーテッド チロシンキナーゼ阻害剤
US6794393B1 (en) 1999-10-19 2004-09-21 Merck & Co., Inc. Tyrosine kinase inhibitors
JP5007007B2 (ja) * 1999-11-15 2012-08-22 ミルテニイ バイオテック ゲゼルシャフト ミット ベシュレンクテル ハフツング 樹状細胞に特異的な抗原結合フラグメント、その組成物および使用方法、それによって認識される抗原およびそれによって得られる細胞
US6420382B2 (en) 2000-02-25 2002-07-16 Merck & Co., Inc. Tyrosine kinase inhibitors
US6313138B1 (en) 2000-02-25 2001-11-06 Merck & Co., Inc. Tyrosine kinase inhibitors
AU2002346053B2 (en) 2001-06-22 2008-03-13 Merck & Co., Inc. Tyrosine kinase inhibitors
WO2003011836A1 (en) 2001-08-01 2003-02-13 Merck & Co., Inc. Tyrosine kinase inhibitors
US6927293B2 (en) 2001-08-30 2005-08-09 Merck & Co., Inc. Tyrosine kinase inhibitors
US8246959B1 (en) * 2003-08-01 2012-08-21 University Of Washington Dendritic cell-associated lectin-like molecules, compositions and methods of use
US7908091B2 (en) 2006-03-17 2011-03-15 Prometheus Laboratories Inc. Methods of predicting and monitoring tyrosine kinase inhibitor therapy
CA2717656A1 (en) * 2007-02-23 2008-08-28 Baylor Research Institute Activation of human antigen-presenting cells through clec-6
JP5641508B2 (ja) * 2010-02-23 2014-12-17 国立大学法人 東京大学 樹状細胞免疫受容体刺激剤
JP6736540B2 (ja) * 2014-07-21 2020-08-05 ノバルティス アーゲー Cll−1キメラ抗原受容体を使用した癌の処置
PL3529262T3 (pl) 2016-10-21 2021-12-27 Inserm - Institut National De La Santé Et De La Recherche Médicale Sposoby wspomagania odpowiedzi limfocytów t

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