CY1124584T1 - Μεθοδοι προωθησης της αποκρισης τ κυτταρων - Google Patents

Μεθοδοι προωθησης της αποκρισης τ κυτταρων

Info

Publication number
CY1124584T1
CY1124584T1 CY20211100839T CY211100839T CY1124584T1 CY 1124584 T1 CY1124584 T1 CY 1124584T1 CY 20211100839 T CY20211100839 T CY 20211100839T CY 211100839 T CY211100839 T CY 211100839T CY 1124584 T1 CY1124584 T1 CY 1124584T1
Authority
CY
Cyprus
Prior art keywords
clec
promoting
cell
methods
cell response
Prior art date
Application number
CY20211100839T
Other languages
Greek (el)
English (en)
Inventor
Géraldine Teppaz
Nicolas Poirier
Bernard Vanhove
Vanessa GAUTTIER
Elise CHIFFOLEAU
Original Assignee
Inserm - Institut National De La Santé Et De La Recherche Médicale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inserm - Institut National De La Santé Et De La Recherche Médicale filed Critical Inserm - Institut National De La Santé Et De La Recherche Médicale
Publication of CY1124584T1 publication Critical patent/CY1124584T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4726—Lectins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1732—Lectins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/7056—Lectin superfamily, e.g. CD23, CD72
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CY20211100839T 2016-10-21 2021-09-24 Μεθοδοι προωθησης της αποκρισης τ κυτταρων CY1124584T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16306381 2016-10-21
EP17305988 2017-07-24
PCT/EP2017/076911 WO2018073440A1 (en) 2016-10-21 2017-10-20 Methods for promoting t cells response

Publications (1)

Publication Number Publication Date
CY1124584T1 true CY1124584T1 (el) 2022-07-22

Family

ID=60293924

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20211100839T CY1124584T1 (el) 2016-10-21 2021-09-24 Μεθοδοι προωθησης της αποκρισης τ κυτταρων

Country Status (21)

Country Link
US (3) US11365257B2 (enExample)
EP (2) EP3529262B1 (enExample)
JP (2) JP7032396B6 (enExample)
KR (1) KR102646708B1 (enExample)
CN (1) CN110291102A (enExample)
AU (1) AU2017345286B2 (enExample)
CA (1) CA3039348C (enExample)
CY (1) CY1124584T1 (enExample)
DK (1) DK3529262T3 (enExample)
ES (2) ES2883678T3 (enExample)
HR (1) HRP20211544T1 (enExample)
HU (1) HUE056016T2 (enExample)
IL (1) IL266111B (enExample)
LT (1) LT3529262T (enExample)
MA (1) MA46570B1 (enExample)
MD (1) MD3529262T2 (enExample)
PL (1) PL3529262T3 (enExample)
RS (1) RS62463B1 (enExample)
SI (1) SI3529262T1 (enExample)
SM (1) SMT202100555T1 (enExample)
WO (1) WO2018073440A1 (enExample)

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* Cited by examiner, † Cited by third party
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PL3529262T3 (pl) * 2016-10-21 2021-12-27 Inserm - Institut National De La Santé Et De La Recherche Médicale Sposoby wspomagania odpowiedzi limfocytów t
IL268895B2 (en) 2017-02-28 2025-05-01 Vor Biopharma Inc Compositions and methods for inhibition of lineage specific proteins
WO2020047164A1 (en) 2018-08-28 2020-03-05 Vor Biopharma, Inc Genetically engineered hematopoietic stem cells and uses thereof
CA3159155A1 (en) * 2019-12-05 2021-06-10 Ose Immunotherapeutics Anti-clec-1a antibodies and antigen-binding fragment thereof
CN113156140A (zh) * 2021-03-05 2021-07-23 青岛大学附属医院 C型凝集素样受体-1作为真菌性角膜炎的治疗标志物的应用
US12448454B2 (en) 2021-06-08 2025-10-21 Inserm (Institut National De La Sante Et De La Recherche Medicale) Humanized anti-CLEC-1A antibodies and antigen-binding fragments thereof
CN118510534A (zh) 2021-11-09 2024-08-16 Ose免疫疗法 Clec-1配体的识别及其用途
WO2024028347A1 (en) 2022-08-01 2024-02-08 Ose Immunotherapeutics Heterodimeric fc-clec-1 fusion molecule and uses thereof
WO2025032213A1 (en) 2023-08-10 2025-02-13 Ose Immunotherapeutics Identification of hla-dra as a ligand of clec-1 and uses thereof

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US5567610A (en) 1986-09-04 1996-10-22 Bioinvent International Ab Method of producing human monoclonal antibodies and kit therefor
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US5175384A (en) 1988-12-05 1992-12-29 Genpharm International Transgenic mice depleted in mature t-cells and methods for making transgenic mice
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PL3529262T3 (pl) 2016-10-21 2021-12-27 Inserm - Institut National De La Santé Et De La Recherche Médicale Sposoby wspomagania odpowiedzi limfocytów t

Also Published As

Publication number Publication date
SMT202100555T1 (it) 2021-11-12
JP2022065159A (ja) 2022-04-26
MA46570B1 (fr) 2021-10-29
CN110291102A (zh) 2019-09-27
CA3039348A1 (en) 2018-04-26
EP3950709A1 (en) 2022-02-09
MD3529262T2 (ro) 2022-01-31
EP3950709B1 (en) 2024-02-14
JP7404418B2 (ja) 2023-12-25
JP7404418B6 (ja) 2024-01-26
US20220281983A1 (en) 2022-09-08
WO2018073440A1 (en) 2018-04-26
US20190309075A1 (en) 2019-10-10
IL266111B (en) 2022-09-01
IL266111A (en) 2019-06-30
JP2020503252A (ja) 2020-01-30
AU2017345286A1 (en) 2019-04-18
EP3529262B1 (en) 2021-07-21
HUE056016T2 (hu) 2022-01-28
US12091464B2 (en) 2024-09-17
HRP20211544T1 (hr) 2022-01-07
LT3529262T (lt) 2021-11-10
KR102646708B1 (ko) 2024-03-12
JP7032396B2 (ja) 2022-03-08
KR20190068605A (ko) 2019-06-18
EP3529262A1 (en) 2019-08-28
SI3529262T1 (sl) 2021-12-31
CA3039348C (en) 2023-09-05
ES2978486T3 (es) 2024-09-13
PL3529262T3 (pl) 2021-12-27
US11365257B2 (en) 2022-06-21
RS62463B1 (sr) 2021-11-30
AU2017345286B2 (en) 2023-08-03
US20240400695A1 (en) 2024-12-05
MA46570A (fr) 2021-03-31
JP7032396B6 (ja) 2022-03-22
DK3529262T3 (da) 2021-09-20
ES2883678T3 (es) 2021-12-09

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