JP2020503050A5 - - Google Patents
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- Publication number
- JP2020503050A5 JP2020503050A5 JP2019535895A JP2019535895A JP2020503050A5 JP 2020503050 A5 JP2020503050 A5 JP 2020503050A5 JP 2019535895 A JP2019535895 A JP 2019535895A JP 2019535895 A JP2019535895 A JP 2019535895A JP 2020503050 A5 JP2020503050 A5 JP 2020503050A5
- Authority
- JP
- Japan
- Prior art keywords
- sulfhydrylase
- serine
- aromatic
- homoserin
- branched
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000003118 aryl group Chemical group 0.000 claims description 22
- 229910052739 hydrogen Inorganic materials 0.000 claims description 15
- 238000000034 method Methods 0.000 claims description 15
- 239000001257 hydrogen Substances 0.000 claims description 14
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 12
- 125000004432 carbon atom Chemical group C* 0.000 claims description 11
- 125000004122 cyclic group Chemical group 0.000 claims description 11
- 125000005842 heteroatom Chemical group 0.000 claims description 11
- 150000008116 organic polysulfides Chemical class 0.000 claims description 11
- 229920001021 polysulfide Polymers 0.000 claims description 11
- 125000001183 hydrocarbyl group Chemical group 0.000 claims description 10
- 239000005077 polysulfide Substances 0.000 claims description 9
- 150000008117 polysulfides Polymers 0.000 claims description 9
- 150000001875 compounds Chemical class 0.000 claims description 6
- 229910052783 alkali metal Inorganic materials 0.000 claims description 4
- 150000001340 alkali metals Chemical class 0.000 claims description 4
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 3
- 229910052784 alkaline earth metal Inorganic materials 0.000 claims description 3
- 150000001342 alkaline earth metals Chemical class 0.000 claims description 3
- 229910052799 carbon Inorganic materials 0.000 claims description 3
- 102000004190 Enzymes Human genes 0.000 claims description 2
- 108090000790 Enzymes Proteins 0.000 claims description 2
- 238000006243 chemical reaction Methods 0.000 claims description 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 2
- 230000002194 synthesizing effect Effects 0.000 claims description 2
- 229960001153 serine Drugs 0.000 claims 10
- UKAUYVFTDYCKQA-VKHMYHEASA-N L-homoserine Chemical class OC(=O)[C@@H](N)CCO UKAUYVFTDYCKQA-VKHMYHEASA-N 0.000 claims 5
- UKAUYVFTDYCKQA-UHFFFAOYSA-N -2-Amino-4-hydroxybutanoic acid Natural products OC(=O)C(N)CCO UKAUYVFTDYCKQA-UHFFFAOYSA-N 0.000 claims 4
- 150000008550 L-serines Chemical class 0.000 claims 4
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims 4
- LFZGUGJDVUUGLK-REOHCLBHSA-N L-serine O-sulfate Chemical compound OC(=O)[C@@H](N)COS(O)(=O)=O LFZGUGJDVUUGLK-REOHCLBHSA-N 0.000 claims 2
- VZXPDPZARILFQX-BYPYZUCNSA-N O-acetyl-L-serine Chemical compound CC(=O)OC[C@H]([NH3+])C([O-])=O VZXPDPZARILFQX-BYPYZUCNSA-N 0.000 claims 2
- ZAHSBRLHJRVFAU-BYPYZUCNSA-N O-succinyl-L-serine Chemical compound OC(=O)[C@@H](N)COC(=O)CCC(O)=O ZAHSBRLHJRVFAU-BYPYZUCNSA-N 0.000 claims 2
- BZQFBWGGLXLEPQ-REOHCLBHSA-N phosphoserine Chemical compound OC(=O)[C@@H](N)COP(O)(O)=O BZQFBWGGLXLEPQ-REOHCLBHSA-N 0.000 claims 2
- LEVWYRKDKASIDU-IMJSIDKUSA-N L-cystine Chemical compound [O-]C(=O)[C@@H]([NH3+])CSSC[C@H]([NH3+])C([O-])=O LEVWYRKDKASIDU-IMJSIDKUSA-N 0.000 claims 1
- FFFHZYDWPBMWHY-VKHMYHEASA-N L-homocysteine Chemical compound OC(=O)[C@@H](N)CCS FFFHZYDWPBMWHY-VKHMYHEASA-N 0.000 claims 1
- 102000035195 Peptidases Human genes 0.000 claims 1
- 108091005804 Peptidases Proteins 0.000 claims 1
- 230000003197 catalytic effect Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 230000014509 gene expression Effects 0.000 claims 1
- 238000002955 isolation Methods 0.000 claims 1
- 238000005461 lubrication Methods 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 235000019833 protease Nutrition 0.000 claims 1
- 238000000926 separation method Methods 0.000 claims 1
- 238000004073 vulcanization Methods 0.000 claims 1
- 239000004215 Carbon black (E152) Substances 0.000 description 1
- 238000007306 functionalization reaction Methods 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1663492 | 2016-12-29 | ||
| FR1663492A FR3061493B1 (fr) | 2016-12-29 | 2016-12-29 | Procede de synthese de polysulfures fonctionnalises |
| PCT/FR2017/053782 WO2018122511A1 (fr) | 2016-12-29 | 2017-12-21 | Procédé de synthèse de polysulfures fonctionnalisés |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020503050A JP2020503050A (ja) | 2020-01-30 |
| JP2020503050A5 true JP2020503050A5 (https=) | 2021-04-15 |
| JP7022755B2 JP7022755B2 (ja) | 2022-02-18 |
Family
ID=58707674
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019535895A Active JP7022755B2 (ja) | 2016-12-29 | 2017-12-21 | 官能化ポリスルフィド合成法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US11578345B2 (https=) |
| EP (1) | EP3562949A1 (https=) |
| JP (1) | JP7022755B2 (https=) |
| KR (1) | KR102471281B1 (https=) |
| CN (1) | CN110088289A (https=) |
| FR (1) | FR3061493B1 (https=) |
| MX (1) | MX2019007570A (https=) |
| MY (1) | MY193946A (https=) |
| WO (1) | WO2018122511A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3112549A1 (fr) * | 2020-07-20 | 2022-01-21 | Arkema France | Procede ameliore de synthese de mercaptans fonctionnalises |
| FR3117115B1 (fr) * | 2020-12-04 | 2023-05-05 | Arkema France | Procede de synthese de mercaptans fonctionnalises sous pression d’h2s |
| AR133742A1 (es) * | 2023-09-08 | 2025-10-29 | Arkema France | Fluidos lubricantes mejorados y nuevos aditivos funcionales con azufre |
| CN121794352A (zh) * | 2023-09-08 | 2026-04-03 | 阿科玛法国公司 | 改进的润滑脂和新型含硫功能添加剂 |
| FR3164723A1 (fr) * | 2024-07-22 | 2026-01-23 | Arkema France | Fluides lubrifiants a base aqueuse ameliores |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3022351A (en) * | 1957-03-07 | 1962-02-20 | Phillips Petroleum Co | Production of organic polysulfides |
| FR2678601B1 (fr) * | 1991-07-01 | 1993-10-22 | Commissariat Energie Atomique | Procede de preparation de sulfures et d'acides amines marques au soufre 35. |
| JP3620221B2 (ja) | 1996-11-25 | 2005-02-16 | 三菱化学株式会社 | ホモシスチンの製造法 |
| US6579705B2 (en) | 2001-04-04 | 2003-06-17 | Consortium Fur Elektrochemische Industrie Gmbh | Process for preparing non-proteinogenic L-amino acids |
| KR100905381B1 (ko) | 2006-07-28 | 2009-06-30 | 씨제이제일제당 (주) | Ｌ-메치오닌 전구체 생산 균주 및 상기 ｌ-메치오닌전구체로부터의 ｌ-메치오닌 및 유기산의 생산방법 |
| US8680151B2 (en) | 2010-02-11 | 2014-03-25 | Fred Hutchinson Cancer Research Center | Compounds, compositions and methods for treating or preventing hypoxic or ischemic injury |
| FR2965561B1 (fr) * | 2010-10-05 | 2012-08-31 | Adisseo France Sas | Procede de preparation d?un acide amine a partir de 2-aminobutyrolactone |
| BR112014004588B1 (pt) | 2011-09-02 | 2019-12-31 | Arkema France | processo para a conversão enzimática de um precursor de l-metionina com metil mercaptano para obter l-metionina e processo para a preparação de l-metionina |
| WO2017188355A1 (ja) * | 2016-04-28 | 2017-11-02 | 国立大学法人 熊本大学 | イオウ原子を同位体標識したシステイン及びシステイン誘導体の合成法の確立 |
-
2016
- 2016-12-29 FR FR1663492A patent/FR3061493B1/fr active Active
-
2017
- 2017-12-21 CN CN201780081528.8A patent/CN110088289A/zh active Pending
- 2017-12-21 JP JP2019535895A patent/JP7022755B2/ja active Active
- 2017-12-21 KR KR1020197021010A patent/KR102471281B1/ko active Active
- 2017-12-21 MY MYPI2019003730A patent/MY193946A/en unknown
- 2017-12-21 EP EP17829270.2A patent/EP3562949A1/fr active Pending
- 2017-12-21 MX MX2019007570A patent/MX2019007570A/es unknown
- 2017-12-21 WO PCT/FR2017/053782 patent/WO2018122511A1/fr not_active Ceased
- 2017-12-21 US US16/473,900 patent/US11578345B2/en active Active
-
2023
- 2023-01-24 US US18/100,801 patent/US20230159967A1/en active Pending
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