JP2020502142A5 - - Google Patents

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JP2020502142A5
JP2020502142A5 JP2019531922A JP2019531922A JP2020502142A5 JP 2020502142 A5 JP2020502142 A5 JP 2020502142A5 JP 2019531922 A JP2019531922 A JP 2019531922A JP 2019531922 A JP2019531922 A JP 2019531922A JP 2020502142 A5 JP2020502142 A5 JP 2020502142A5
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pharmaceutical composition
composition according
human subject
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rnai agent
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JP2019531922A
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JP2020502142A (ja
JP7058656B2 (ja
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Priority claimed from PCT/US2017/066631 external-priority patent/WO2018112320A1/en
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Priority to JP2022002865A priority Critical patent/JP2022062035A/ja
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Priority to JP2023151150A priority patent/JP2024009806A/ja
Priority to JP2025066193A priority patent/JP2025118649A/ja
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JP2019531922A 2016-12-16 2017-12-15 トランスサイレチン(TTR)iRNA組成物を用いてTTR関連疾患を治療または予防するための方法 Active JP7058656B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2022002865A JP2022062035A (ja) 2016-12-16 2022-01-12 トランスサイレチン(TTR)iRNA組成物を用いてTTR関連疾患を治療または予防するための方法
JP2023151150A JP2024009806A (ja) 2016-12-16 2023-09-19 トランスサイレチン(TTR)iRNA組成物を用いてTTR関連疾患を治療または予防するための方法
JP2025066193A JP2025118649A (ja) 2016-12-16 2025-04-14 トランスサイレチン(TTR)iRNA組成物を用いてTTR関連疾患を治療または予防するための方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662435127P 2016-12-16 2016-12-16
US62/435,127 2016-12-16
PCT/US2017/066631 WO2018112320A1 (en) 2016-12-16 2017-12-15 Methods for treating or preventing ttr-associated diseases using transthyretin (ttr) irna compositions

Related Child Applications (1)

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JP2022002865A Division JP2022062035A (ja) 2016-12-16 2022-01-12 トランスサイレチン(TTR)iRNA組成物を用いてTTR関連疾患を治療または予防するための方法

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JP2020502142A JP2020502142A (ja) 2020-01-23
JP2020502142A5 true JP2020502142A5 (cg-RX-API-DMAC7.html) 2021-01-28
JP7058656B2 JP7058656B2 (ja) 2022-04-22

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JP2019531922A Active JP7058656B2 (ja) 2016-12-16 2017-12-15 トランスサイレチン(TTR)iRNA組成物を用いてTTR関連疾患を治療または予防するための方法
JP2022002865A Pending JP2022062035A (ja) 2016-12-16 2022-01-12 トランスサイレチン(TTR)iRNA組成物を用いてTTR関連疾患を治療または予防するための方法
JP2023151150A Withdrawn JP2024009806A (ja) 2016-12-16 2023-09-19 トランスサイレチン(TTR)iRNA組成物を用いてTTR関連疾患を治療または予防するための方法
JP2025066193A Pending JP2025118649A (ja) 2016-12-16 2025-04-14 トランスサイレチン(TTR)iRNA組成物を用いてTTR関連疾患を治療または予防するための方法

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JP2022002865A Pending JP2022062035A (ja) 2016-12-16 2022-01-12 トランスサイレチン(TTR)iRNA組成物を用いてTTR関連疾患を治療または予防するための方法
JP2023151150A Withdrawn JP2024009806A (ja) 2016-12-16 2023-09-19 トランスサイレチン(TTR)iRNA組成物を用いてTTR関連疾患を治療または予防するための方法
JP2025066193A Pending JP2025118649A (ja) 2016-12-16 2025-04-14 トランスサイレチン(TTR)iRNA組成物を用いてTTR関連疾患を治療または予防するための方法

Country Status (9)

Country Link
US (2) US20190350962A1 (cg-RX-API-DMAC7.html)
EP (1) EP3555292A1 (cg-RX-API-DMAC7.html)
JP (4) JP7058656B2 (cg-RX-API-DMAC7.html)
KR (2) KR20190098181A (cg-RX-API-DMAC7.html)
AU (2) AU2017376950B2 (cg-RX-API-DMAC7.html)
SG (1) SG10201913552UA (cg-RX-API-DMAC7.html)
TW (2) TWI865997B (cg-RX-API-DMAC7.html)
WO (1) WO2018112320A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA202306507B (cg-RX-API-DMAC7.html)

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JP2022548031A (ja) * 2019-09-13 2022-11-16 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 脂質ナノ粒子によって送達されるcrispr/casシステムを使用する動物における転写調節
EP4055165A1 (en) * 2019-11-06 2022-09-14 Alnylam Pharmaceuticals, Inc. Transthyretin (ttr) irna compositions and methods of use thereof for treating or preventing ttr-associated ocular diseases
JP2023516748A (ja) 2020-03-06 2023-04-20 アルナイラム ファーマシューティカルズ, インコーポレイテッド トランスサイレチン(ttr)の発現を阻害するための組成物および方法
WO2022112919A1 (en) 2020-11-25 2022-06-02 Pfizer Inc. (aza)benzothiazolyl substituted pyrazole compounds
WO2022162153A1 (en) 2021-01-30 2022-08-04 E-Therapeutics Plc Conjugated oligonucleotide compounds, methods of making and uses thereof
WO2022162154A1 (en) * 2021-01-30 2022-08-04 E-Therapeutics Plc Conjugated oligonucleotide compounds, methods of making and uses thereof
EP4351541A2 (en) 2021-06-08 2024-04-17 Alnylam Pharmaceuticals, Inc. Compositions and methods for treating or preventing stargardt's disease and/or retinal binding protein 4 (rbp4)-associated disorders
KR20240042004A (ko) 2021-08-03 2024-04-01 알닐람 파마슈티칼스 인코포레이티드 트랜스티레틴(TTR) iRNA 조성물 및 이의 사용 방법
IL317824A (en) * 2022-07-11 2025-02-01 Sanegene Bio Usa Inc Ribose derivatives modified at the '2' position and methods of use
WO2024023262A2 (en) * 2022-07-27 2024-02-01 E-Therapeutics Plc Nucleic acid compounds
TW202440921A (zh) * 2022-12-05 2024-10-16 美商美國禮來大藥廠 經修飾之寡核苷酸
AR131389A1 (es) * 2022-12-16 2025-03-12 Amgen Inc CONSTRUCTOS DE ARNi PARA INHIBIR LA EXPRESIÓN DE TTR Y MÉTODOS DE USO DE LOS MISMOS
WO2024138111A1 (en) * 2022-12-23 2024-06-27 Eli Lilly And Company Novel rna therapeutics and uses thereof
EP4638746A1 (en) * 2022-12-23 2025-10-29 Eli Lilly and Company Novel rna therapeutics and uses thereof
WO2025128632A1 (en) * 2023-12-12 2025-06-19 Alnylam Pharmaceuticals, Inc. Methods and compositions for treating ketohexokinase (khk)-associated diseases
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