|
US3773919A
(en)
|
1969-10-23 |
1973-11-20 |
Du Pont |
Polylactide-drug mixtures
|
|
US4190328A
(en)
|
1978-12-01 |
1980-02-26 |
Levine Robert A |
Process for detection of blood-borne parasites
|
|
DE2928477C3
(de)
*
|
1979-07-14 |
1982-04-15 |
Battelle-Institut E.V., 6000 Frankfurt |
Vorrichtung zur Freisetzung von Substanzen an definierten Orten des Verdauungstraktes
|
|
US4522811A
(en)
|
1982-07-08 |
1985-06-11 |
Syntex (U.S.A.) Inc. |
Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US4676980A
(en)
|
1985-09-23 |
1987-06-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Target specific cross-linked heteroantibodies
|
|
US5116742A
(en)
|
1986-12-03 |
1992-05-26 |
University Patents, Inc. |
RNA ribozyme restriction endoribonucleases and methods
|
|
US4987071A
(en)
|
1986-12-03 |
1991-01-22 |
University Patents, Inc. |
RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods
|
|
US4904582A
(en)
|
1987-06-11 |
1990-02-27 |
Synthetic Genetics |
Novel amphiphilic nucleic acid conjugates
|
|
JP2681061B2
(ja)
|
1988-06-08 |
1997-11-19 |
ロンドン・ダイアグノスティック・インコーポレーテッド |
検出可能なシグナルのセンシタイザー誘導発生を利用したアッセイ
|
|
US6251581B1
(en)
|
1991-05-22 |
2001-06-26 |
Dade Behring Marburg Gmbh |
Assay method utilizing induced luminescence
|
|
US5314805A
(en)
|
1991-10-28 |
1994-05-24 |
Molecular Probes, Inc. |
Dual-fluorescence cell viability assay using ethidium homodimer and calcein AM
|
|
US5596090A
(en)
|
1992-07-24 |
1997-01-21 |
The United States Of America As Represented By The Secretary Of The Navy |
Antisense oligonucleotides directed against human VCAM-1 RNA
|
|
EP0656946B2
(en)
|
1992-08-21 |
2010-03-31 |
Vrije Universiteit Brussel |
Immunoglobulins devoid of light chains
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
US6267958B1
(en)
|
1995-07-27 |
2001-07-31 |
Genentech, Inc. |
Protein formulation
|
|
US5763602A
(en)
|
1996-10-01 |
1998-06-09 |
Li; Ying-Syi |
Methods of syntheses of phthalocyanine compounds
|
|
US5919792A
(en)
|
1996-10-30 |
1999-07-06 |
Merck & Co., Inc. |
Integrin antagonists
|
|
AU6780398A
(en)
|
1997-03-28 |
1998-10-22 |
Du Pont Merck Pharmaceutical Company, The |
Heterocyclic integrin inhibitor prodrugs
|
|
US6171586B1
(en)
|
1997-06-13 |
2001-01-09 |
Genentech, Inc. |
Antibody formulation
|
|
PT1007033E
(pt)
|
1997-08-28 |
2008-07-22 |
Novartis Ag |
Antagonistas do antigénio-1 da função de linfócitos
|
|
US6506559B1
(en)
|
1997-12-23 |
2003-01-14 |
Carnegie Institute Of Washington |
Genetic inhibition by double-stranded RNA
|
|
AU2679899A
(en)
|
1998-02-18 |
1999-09-06 |
Dade Behring Inc. |
Chemiluminescent compositions for use in detection of multiple analytes
|
|
US6833373B1
(en)
|
1998-12-23 |
2004-12-21 |
G.D. Searle & Co. |
Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
|
|
BR0007663A
(pt)
|
1999-01-22 |
2002-05-07 |
Elan Pharm Inc |
Derivados de acila para uso no tratamento de doenças relacionadas com o vla-4
|
|
US8636648B2
(en)
*
|
1999-03-01 |
2014-01-28 |
West View Research, Llc |
Endoscopic smart probe
|
|
US6331530B1
(en)
|
1999-07-13 |
2001-12-18 |
The Trustees Of Columbia University In The City Of New York |
Hydrophilic carrier for photosensitizers that cleaves when they catalyze the formation of singlet oxygen
|
|
US6703248B1
(en)
|
1999-12-15 |
2004-03-09 |
Dade Behring Marburg Gmbh |
Particles for diagnostic and therapeutic use
|
|
ES2341843T3
(es)
|
2000-02-03 |
2010-06-29 |
EISAI R&D MANAGEMENT CO., LTD. |
Inhibidores de la expresion de integrina.
|
|
US7074408B2
(en)
|
2000-02-25 |
2006-07-11 |
Immunex Corporation |
Use of integrin antagonists to inhibit angiogenesis
|
|
WO2001068586A2
(en)
|
2000-03-14 |
2001-09-20 |
Novartis Ag |
α4β1 AND α4β7 INTEGRIN INHIBITORS
|
|
US6794506B2
(en)
|
2000-07-21 |
2004-09-21 |
Elan Pharmaceuticals, Inc. |
3-(heteroaryl) alanine derivatives-inhibitors of leukocyte adhesion mediated by VLA-4
|
|
DE10040105A1
(de)
|
2000-08-17 |
2002-02-28 |
Merck Patent Gmbh |
Peptid- und Peptidmimetika-Derivate mit Integrin-Inhibitor-Eigenschaften
|
|
CA2435205A1
(en)
*
|
2001-01-22 |
2002-08-01 |
V-Target Technologies Ltd. |
Ingestible device
|
|
US7160258B2
(en)
*
|
2001-06-26 |
2007-01-09 |
Entrack, Inc. |
Capsule and method for treating or diagnosing the intestinal tract
|
|
DE10204789A1
(de)
|
2002-02-06 |
2003-08-14 |
Merck Patent Gmbh |
Inhibitoren des Integrins alpha¶v¶beta6
|
|
KR20040108655A
(ko)
|
2002-03-05 |
2004-12-24 |
아클라라 바이오사이언시스 인코퍼레이티드 |
막-결합된 민감제를 사용하는 복합 분석법
|
|
EP2336185A1
(en)
|
2002-03-13 |
2011-06-22 |
Biogen Idec Inc. |
Anti- alpha v beta 6 antibodies
|
|
CA2491355A1
(en)
|
2002-07-05 |
2004-01-15 |
Temrel Limited |
Controlled release compositions comprising coated pellets having non-uniform coating thicknesses
|
|
US9211259B2
(en)
|
2002-11-29 |
2015-12-15 |
Foamix Pharmaceuticals Ltd. |
Antibiotic kit and composition and uses thereof
|
|
RU2334506C2
(ru)
*
|
2003-01-29 |
2008-09-27 |
И-Пилл Фарма Лтд. |
Активная доставка лекарственного средства в желудочно-кишечном тракте
|
|
DE10305784A1
(de)
|
2003-02-12 |
2004-08-26 |
Merck Patent Gmbh |
Verfahren zur Herstellug bicyclischer aromatischer Aminosäuren sowie deren Zwischenprodukte
|
|
US20060104968A1
(en)
|
2003-03-05 |
2006-05-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
|
|
US7871607B2
(en)
|
2003-03-05 |
2011-01-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
|
|
US7402398B2
(en)
|
2003-07-17 |
2008-07-22 |
Monogram Biosciences, Inc. |
Measuring receptor homodimerization
|
|
CN1874789A
(zh)
|
2003-09-23 |
2006-12-06 |
光科学公司 |
用于光动力疗法的缀合物
|
|
DE602004014795D1
(de)
|
2003-10-01 |
2008-08-14 |
Merck Patent Gmbh |
Alfavbeta3 und alfavbeta6 integrin antagonisten als antifibrotische mittel
|
|
WO2005035495A2
(en)
|
2003-10-08 |
2005-04-21 |
Nicholas Piramal India Limited |
Fibrinogen receptor antagonists and their use
|
|
ATE551339T1
(de)
|
2003-11-05 |
2012-04-15 |
Sarcode Bioscience Inc |
Modulatoren der zellulären adhäsion
|
|
BRPI0509271A
(pt)
|
2004-03-26 |
2007-09-04 |
Lek Pharmaceuticals |
formas de dosagens farmacêuticas gastrorresistentes compreendendo ácido n-(2-(2-ftalimidaetóxi)-acetil-l-alanil-d-glutámico(lk-4 23)
|
|
AU2005277567A1
(en)
|
2004-08-16 |
2006-03-02 |
Medimmune, Llc |
Integrin antagonists with enhanced antibody dependent cell-mediated cytotoxicity activity
|
|
DK176145B1
(da)
|
2004-09-23 |
2006-10-02 |
Guldmann V As |
Kobling
|
|
JO3000B1
(ar)
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
|
DE102004059613A1
(de)
*
|
2004-12-10 |
2006-06-14 |
Liedtke, Rainer K., Dr. |
Zusammensetzung und Methode einer topischen Therapie von Neurodermitis
|
|
EP1841490A2
(en)
*
|
2005-01-18 |
2007-10-10 |
Koninklijke Philips Electronics N.V. |
Electronically controlled capsule
|
|
ITMI20050328A1
(it)
|
2005-03-03 |
2006-09-04 |
Univ Degli Studi Milano |
Composti peptidomimetrici e preparazione di derivati biologicamente attivi
|
|
WO2007054128A1
(en)
|
2005-11-14 |
2007-05-18 |
Dominion Pharmakine S.L. |
Novel inhibitors of the lfa-1/icam-1 interaction, and uses thereof
|
|
GB0507918D0
(en)
|
2005-04-19 |
2005-05-25 |
Novartis Ag |
Organic compounds
|
|
US8030328B2
(en)
|
2005-05-20 |
2011-10-04 |
Elan Pharmaceuticals, Inc. |
Imidazolone phenylalanine derivatives
|
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
TWI323734B
(en)
|
2005-08-19 |
2010-04-21 |
Abbott Lab |
Dual variable domain immunoglobulin and uses thereof
|
|
GB0520378D0
(en)
|
2005-10-06 |
2005-11-16 |
Novartis Ag |
Organic compounds
|
|
US7928113B2
(en)
|
2005-11-14 |
2011-04-19 |
University Of Southern California |
Integrin-binding small molecules
|
|
WO2007069635A1
(ja)
|
2005-12-13 |
2007-06-21 |
Daiichi Sankyo Company, Limited |
Vla-4阻害薬
|
|
MY151045A
(en)
|
2006-02-27 |
2014-03-31 |
Elan Pharm Inc |
Pyrimidinyl sulfonamide compounds which inhibit leukocyte adhesion mediated by vla-4
|
|
MY159375A
(en)
|
2006-03-21 |
2016-12-30 |
Genentech Inc |
Combinatorial therapy
|
|
EP2021373A4
(en)
|
2006-05-31 |
2010-06-02 |
Hanwa Chemical Corp |
MONOCLONAL ANTIBODY VCAM-1 SPECIFIC
|
|
JP2009541018A
(ja)
*
|
2006-06-23 |
2009-11-26 |
コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ |
薬剤投与システム
|
|
CA2658612C
(en)
|
2006-08-03 |
2015-11-17 |
Astrazeneca Ab |
Antibodies directed to .alpha.v.beta.6 and uses thereof
|
|
EP2125076B1
(en)
*
|
2007-02-26 |
2012-06-20 |
Duocure, Inc. |
Spray administration of compositions including active agents such as peptides to the gastrointestinal tract
|
|
EP2380564B1
(en)
*
|
2007-04-04 |
2014-10-22 |
Sigmoid Pharma Limited |
An oral pharmaceutical composition
|
|
KR101559596B1
(ko)
|
2007-07-17 |
2015-10-12 |
메르크 파텐트 게엠베하 |
조작 항-알파 v-인테그린 잡종 항체
|
|
WO2009076434A1
(en)
|
2007-12-12 |
2009-06-18 |
Molecular Insight Pharmaceuticals, Inc. |
Inhibitors of integrin vla-4
|
|
WO2011004395A1
(en)
|
2009-07-06 |
2011-01-13 |
Intas Biopharmaceuticals Limited |
Microemulsion formulation for biologicals
|
|
JP6030956B2
(ja)
*
|
2009-08-05 |
2016-11-24 |
テル ハショマー メディカル リサーチ インフラストラクチャー アンド サーヴィシーズ リミテッド |
胃腸管の異常の診断に使える情報を提供する方法と機器
|
|
EP2491057A4
(en)
|
2009-10-23 |
2013-05-29 |
Hanwha Chemical Corp |
HUMAN RECOMBINANT MONOCLONAL ANTIBODY WITH SPECIFIC BINDING TO VCAM-1 AND INHIBITION OF ADHESION AND TRANSMIGRATION BETWEEN LEUKOYZTS AND ENDOTHELIAL CELLS
|
|
ITFI20100019A1
(it)
|
2010-02-12 |
2011-08-13 |
Univ Firenze |
Inibitori peptidomimetici di integrine basati sull'1,2,3-triazolo per la diagnosi e terapia dei tumori.
|
|
US8853149B2
(en)
|
2010-03-19 |
2014-10-07 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Integrin interaction inhibitors for the treatment of cancer
|
|
EP2563405A1
(en)
|
2010-04-30 |
2013-03-06 |
Elan Pharmaceuticals Inc. |
Selective integrin inhibitors
|
|
US9415004B2
(en)
*
|
2010-12-23 |
2016-08-16 |
Rani Therapeutics, Llc |
Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
|
|
US8907081B2
(en)
|
2011-05-27 |
2014-12-09 |
Sharp Laboratories Of America, Inc. |
Long wavelength absorbing porphyrin photosensitizers for dye-sensitized solar cells
|
|
RU2597425C2
(ru)
|
2011-08-17 |
2016-09-10 |
Пирамаль Имэджинг Са |
Соединения для связывания со специфическим для тромбоцитов гликопротеином iib/iiia и их применение для визуализации тромбов
|
|
FR2979346B1
(fr)
|
2011-08-23 |
2013-09-27 |
Univ Joseph Fourier |
Nanocorps anti-vcam-1
|
|
WO2013113326A1
(en)
|
2012-01-31 |
2013-08-08 |
Curevac Gmbh |
Pharmaceutical composition comprising a polymeric carrier cargo complex and at least one protein or peptide antigen
|
|
FR2986432B1
(fr)
|
2012-02-06 |
2014-03-14 |
Univ Lille Ii Droit & Sante |
Proteines 28kda gst provenant de schistosomes pour leur utilisation dans le traitement des maladies inflammatoires auto-immunes engendrant une reponse de type th1 et/ou th17
|
|
GB201207155D0
(en)
|
2012-04-24 |
2012-06-06 |
Isis Innovation |
Antibodies
|
|
US20140349944A1
(en)
|
2013-05-23 |
2014-11-27 |
Musc Foundation For Research Development |
Chaperone-based integrin inhibitors for the treatment of cancer and inflammatory diseases
|
|
RU2015155552A
(ru)
|
2013-05-24 |
2017-06-27 |
Нестек С.А. |
Путеспецифические способы прогнозирования диагноза синдрома раздраженного кишечника
|
|
US10472376B2
(en)
*
|
2013-07-03 |
2019-11-12 |
Takeda Pharmaceutical Company Limited |
Amide compound
|
|
WO2015059569A1
(en)
*
|
2013-09-26 |
2015-04-30 |
Medimetrics Personalized Drug Delivery, B.V. |
Delivery capsule with threshold release
|
|
US20160249793A1
(en)
*
|
2013-12-27 |
2016-09-01 |
Kang-Huai Wang |
Capsule Camera Device with Multi-Spectral Light Sources
|
|
ES2923641T3
(es)
|
2013-12-30 |
2022-09-29 |
Epimab Biotherapeutics Inc |
Inmunoglobulina con Fabs en tándem y usos de la misma
|
|
GB201400442D0
(en)
*
|
2014-01-10 |
2014-02-26 |
Sigmoid Pharma Ltd |
Compositions for use in the treatment of ulcerative colitis
|
|
US10219748B2
(en)
|
2014-01-22 |
2019-03-05 |
Nutech Ventures |
Gastrointestinal sensor implantation system
|
|
WO2015131078A1
(en)
*
|
2014-02-27 |
2015-09-03 |
Biogen Ma Inc. |
Method of assessing risk of pml
|
|
DE102014004843A1
(de)
|
2014-04-02 |
2015-10-08 |
Schaltbau Gmbh |
Gleichstromschütz mit zusätzlicher Schalttauglichkeit für Wechselstromlasten und Polung entgegen der Vorzugsstromrichtung
|
|
CA2955666A1
(en)
|
2014-08-13 |
2016-02-18 |
Cedars-Sinai Medical Center |
Anti-methanogenic compositions and uses thereof
|
|
AU2015319850B2
(en)
*
|
2014-09-25 |
2019-09-26 |
Bt Bidco, Inc. |
Electromechanical pill device with localization capabilities
|
|
US9714288B2
(en)
|
2014-09-30 |
2017-07-25 |
The Regents Of The University Of California |
Antisense compounds and uses thereof
|
|
WO2016099792A1
(en)
*
|
2014-11-19 |
2016-06-23 |
Nano Pharmaceutical Laboratories Llc |
Wireless communications system integrating electronics into orally ingestible products for controlled release of active ingredients
|
|
CN104473611B
(zh)
|
2015-01-19 |
2018-01-30 |
吉林大学 |
具有超声波定位功能的胶囊内窥镜系统
|
|
KR20170122776A
(ko)
|
2015-03-06 |
2017-11-06 |
신세틱 바이오로직스, 인코퍼레이티드 |
마이크로바이옴 보호를 위한 안전하고 유효한 베타-락타마제 투약
|
|
WO2023091991A1
(en)
|
2021-11-17 |
2023-05-25 |
H2 Clipper, Inc. |
Improved system, method and apparatus for airship manufacture using robotics
|