JP2020502125A5 - - Google Patents

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JP2020502125A5
JP2020502125A5 JP2019531759A JP2019531759A JP2020502125A5 JP 2020502125 A5 JP2020502125 A5 JP 2020502125A5 JP 2019531759 A JP2019531759 A JP 2019531759A JP 2019531759 A JP2019531759 A JP 2019531759A JP 2020502125 A5 JP2020502125 A5 JP 2020502125A5
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JP
Japan
Prior art keywords
ingestible device
ingestible
cecum
integrin inhibitor
reservoir
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JP2019531759A
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English (en)
Japanese (ja)
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JP2020502125A (ja
JP7150723B2 (ja
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Priority claimed from PCT/US2017/066441 external-priority patent/WO2018112215A1/en
Publication of JP2020502125A publication Critical patent/JP2020502125A/ja
Publication of JP2020502125A5 publication Critical patent/JP2020502125A5/ja
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JP2019531759A 2016-12-14 2017-12-14 消化管疾病のインテグリン阻害薬による治療 Active JP7150723B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201662434369P 2016-12-14 2016-12-14
US62/434,369 2016-12-14
US201762478863P 2017-03-30 2017-03-30
US62/478,863 2017-03-30
US201762545220P 2017-08-14 2017-08-14
US62/545,220 2017-08-14
US201762583804P 2017-11-09 2017-11-09
US62/583,804 2017-11-09
PCT/US2017/066441 WO2018112215A1 (en) 2016-12-14 2017-12-14 Treatment of a disease of the gastrointestinal tract with an integrin inhibitor

Publications (3)

Publication Number Publication Date
JP2020502125A JP2020502125A (ja) 2020-01-23
JP2020502125A5 true JP2020502125A5 (enExample) 2021-01-28
JP7150723B2 JP7150723B2 (ja) 2022-10-11

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Application Number Title Priority Date Filing Date
JP2019531759A Active JP7150723B2 (ja) 2016-12-14 2017-12-14 消化管疾病のインテグリン阻害薬による治療

Country Status (11)

Country Link
US (1) US20200253506A1 (enExample)
EP (2) EP3554539B9 (enExample)
JP (1) JP7150723B2 (enExample)
KR (1) KR20190095936A (enExample)
CN (2) CN110167589B (enExample)
AU (1) AU2017376801B9 (enExample)
BR (1) BR112019012071A2 (enExample)
CA (1) CA3045931A1 (enExample)
MX (1) MX2019006867A (enExample)
TW (1) TW201834710A (enExample)
WO (1) WO2018112215A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3085330A1 (en) * 2017-12-14 2019-06-20 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with a s1p modulator
US20200390426A1 (en) * 2017-12-22 2020-12-17 Aobiome Llc Devices and methods for microbiome sampling
WO2019246455A1 (en) * 2018-06-20 2019-12-26 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an integrin inhibitor
WO2020070818A1 (ja) * 2018-10-03 2020-04-09 オリンパス株式会社 内視鏡装置及び観察時間計測方法
EP3956358A4 (en) * 2019-04-17 2023-01-25 Millennium Pharmaceuticals, Inc. COMBINATION THERAPY WITH ALPHA4BETA7 INHIBITOR AND IL-23 INHIBITOR
CN115666704B (zh) * 2019-12-13 2025-09-26 比特比德科有限责任公司 用于将治疗剂递送至胃肠道的可摄取装置
JP7444991B2 (ja) * 2019-12-16 2024-03-06 イーライ リリー アンド カンパニー 消化器サンプリングのためのカプセル
CN117729881A (zh) * 2021-03-05 2024-03-19 光疗胶囊医学有限公司 用于胃肠位置估计的装置和方法
US20220326255A1 (en) * 2021-04-01 2022-10-13 Medibeacon Inc. Methods of monitoring mucosal healing
JP7699774B2 (ja) * 2021-09-07 2025-06-30 公立大学法人名古屋市立大学 間質性膀胱炎・膀胱痛症候群の予防又は治療用医薬組成物
CN114659995B (zh) * 2022-05-24 2022-08-23 广东省农业科学院动物科学研究所 一种基于显微高光谱的鱼类诱食剂效果评价方法及系统
CN114907468B (zh) * 2022-06-10 2023-05-23 东莞理工学院 一种仿刺参整合素多克隆抗体、抗原蛋白及其制备方法
CN116027048A (zh) * 2023-02-06 2023-04-28 山东中鸿特检生物科技有限公司 一种细胞因子风暴综合征诊断试剂盒及其应用
AU2024282654A1 (en) 2023-05-30 2025-12-04 Paragon Therapeutics, Inc. Alpha4beta7 integrin antibody compositions and methods of use
WO2025050006A1 (en) * 2023-09-01 2025-03-06 Biora Therapeutics, Inc. Ingestible drug delivery device

Family Cites Families (103)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US4190328A (en) 1978-12-01 1980-02-26 Levine Robert A Process for detection of blood-borne parasites
DE2928477C3 (de) * 1979-07-14 1982-04-15 Battelle-Institut E.V., 6000 Frankfurt Vorrichtung zur Freisetzung von Substanzen an definierten Orten des Verdauungstraktes
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4676980A (en) 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
US5116742A (en) 1986-12-03 1992-05-26 University Patents, Inc. RNA ribozyme restriction endoribonucleases and methods
US4987071A (en) 1986-12-03 1991-01-22 University Patents, Inc. RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods
US4904582A (en) 1987-06-11 1990-02-27 Synthetic Genetics Novel amphiphilic nucleic acid conjugates
JP2681061B2 (ja) 1988-06-08 1997-11-19 ロンドン・ダイアグノスティック・インコーポレーテッド 検出可能なシグナルのセンシタイザー誘導発生を利用したアッセイ
US6251581B1 (en) 1991-05-22 2001-06-26 Dade Behring Marburg Gmbh Assay method utilizing induced luminescence
US5314805A (en) 1991-10-28 1994-05-24 Molecular Probes, Inc. Dual-fluorescence cell viability assay using ethidium homodimer and calcein AM
US5596090A (en) 1992-07-24 1997-01-21 The United States Of America As Represented By The Secretary Of The Navy Antisense oligonucleotides directed against human VCAM-1 RNA
EP0656946B2 (en) 1992-08-21 2010-03-31 Vrije Universiteit Brussel Immunoglobulins devoid of light chains
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
US6267958B1 (en) 1995-07-27 2001-07-31 Genentech, Inc. Protein formulation
US5763602A (en) 1996-10-01 1998-06-09 Li; Ying-Syi Methods of syntheses of phthalocyanine compounds
US5919792A (en) 1996-10-30 1999-07-06 Merck & Co., Inc. Integrin antagonists
AU6780398A (en) 1997-03-28 1998-10-22 Du Pont Merck Pharmaceutical Company, The Heterocyclic integrin inhibitor prodrugs
US6171586B1 (en) 1997-06-13 2001-01-09 Genentech, Inc. Antibody formulation
PT1007033E (pt) 1997-08-28 2008-07-22 Novartis Ag Antagonistas do antigénio-1 da função de linfócitos
US6506559B1 (en) 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
AU2679899A (en) 1998-02-18 1999-09-06 Dade Behring Inc. Chemiluminescent compositions for use in detection of multiple analytes
US6833373B1 (en) 1998-12-23 2004-12-21 G.D. Searle & Co. Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
BR0007663A (pt) 1999-01-22 2002-05-07 Elan Pharm Inc Derivados de acila para uso no tratamento de doenças relacionadas com o vla-4
US8636648B2 (en) * 1999-03-01 2014-01-28 West View Research, Llc Endoscopic smart probe
US6331530B1 (en) 1999-07-13 2001-12-18 The Trustees Of Columbia University In The City Of New York Hydrophilic carrier for photosensitizers that cleaves when they catalyze the formation of singlet oxygen
US6703248B1 (en) 1999-12-15 2004-03-09 Dade Behring Marburg Gmbh Particles for diagnostic and therapeutic use
ES2341843T3 (es) 2000-02-03 2010-06-29 EISAI R&D MANAGEMENT CO., LTD. Inhibidores de la expresion de integrina.
US7074408B2 (en) 2000-02-25 2006-07-11 Immunex Corporation Use of integrin antagonists to inhibit angiogenesis
WO2001068586A2 (en) 2000-03-14 2001-09-20 Novartis Ag α4β1 AND α4β7 INTEGRIN INHIBITORS
US6794506B2 (en) 2000-07-21 2004-09-21 Elan Pharmaceuticals, Inc. 3-(heteroaryl) alanine derivatives-inhibitors of leukocyte adhesion mediated by VLA-4
DE10040105A1 (de) 2000-08-17 2002-02-28 Merck Patent Gmbh Peptid- und Peptidmimetika-Derivate mit Integrin-Inhibitor-Eigenschaften
CA2435205A1 (en) * 2001-01-22 2002-08-01 V-Target Technologies Ltd. Ingestible device
US7160258B2 (en) * 2001-06-26 2007-01-09 Entrack, Inc. Capsule and method for treating or diagnosing the intestinal tract
DE10204789A1 (de) 2002-02-06 2003-08-14 Merck Patent Gmbh Inhibitoren des Integrins alpha¶v¶beta6
KR20040108655A (ko) 2002-03-05 2004-12-24 아클라라 바이오사이언시스 인코퍼레이티드 막-결합된 민감제를 사용하는 복합 분석법
EP2336185A1 (en) 2002-03-13 2011-06-22 Biogen Idec Inc. Anti- alpha v beta 6 antibodies
CA2491355A1 (en) 2002-07-05 2004-01-15 Temrel Limited Controlled release compositions comprising coated pellets having non-uniform coating thicknesses
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
RU2334506C2 (ru) * 2003-01-29 2008-09-27 И-Пилл Фарма Лтд. Активная доставка лекарственного средства в желудочно-кишечном тракте
DE10305784A1 (de) 2003-02-12 2004-08-26 Merck Patent Gmbh Verfahren zur Herstellug bicyclischer aromatischer Aminosäuren sowie deren Zwischenprodukte
US20060104968A1 (en) 2003-03-05 2006-05-18 Halozyme, Inc. Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
US7871607B2 (en) 2003-03-05 2011-01-18 Halozyme, Inc. Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
US7402398B2 (en) 2003-07-17 2008-07-22 Monogram Biosciences, Inc. Measuring receptor homodimerization
CN1874789A (zh) 2003-09-23 2006-12-06 光科学公司 用于光动力疗法的缀合物
DE602004014795D1 (de) 2003-10-01 2008-08-14 Merck Patent Gmbh Alfavbeta3 und alfavbeta6 integrin antagonisten als antifibrotische mittel
WO2005035495A2 (en) 2003-10-08 2005-04-21 Nicholas Piramal India Limited Fibrinogen receptor antagonists and their use
ATE551339T1 (de) 2003-11-05 2012-04-15 Sarcode Bioscience Inc Modulatoren der zellulären adhäsion
BRPI0509271A (pt) 2004-03-26 2007-09-04 Lek Pharmaceuticals formas de dosagens farmacêuticas gastrorresistentes compreendendo ácido n-(2-(2-ftalimidaetóxi)-acetil-l-alanil-d-glutámico(lk-4 23)
AU2005277567A1 (en) 2004-08-16 2006-03-02 Medimmune, Llc Integrin antagonists with enhanced antibody dependent cell-mediated cytotoxicity activity
DK176145B1 (da) 2004-09-23 2006-10-02 Guldmann V As Kobling
JO3000B1 (ar) 2004-10-20 2016-09-05 Genentech Inc مركبات أجسام مضادة .
DE102004059613A1 (de) * 2004-12-10 2006-06-14 Liedtke, Rainer K., Dr. Zusammensetzung und Methode einer topischen Therapie von Neurodermitis
EP1841490A2 (en) * 2005-01-18 2007-10-10 Koninklijke Philips Electronics N.V. Electronically controlled capsule
ITMI20050328A1 (it) 2005-03-03 2006-09-04 Univ Degli Studi Milano Composti peptidomimetrici e preparazione di derivati biologicamente attivi
WO2007054128A1 (en) 2005-11-14 2007-05-18 Dominion Pharmakine S.L. Novel inhibitors of the lfa-1/icam-1 interaction, and uses thereof
GB0507918D0 (en) 2005-04-19 2005-05-25 Novartis Ag Organic compounds
US8030328B2 (en) 2005-05-20 2011-10-04 Elan Pharmaceuticals, Inc. Imidazolone phenylalanine derivatives
US7612181B2 (en) 2005-08-19 2009-11-03 Abbott Laboratories Dual variable domain immunoglobulin and uses thereof
TWI323734B (en) 2005-08-19 2010-04-21 Abbott Lab Dual variable domain immunoglobulin and uses thereof
GB0520378D0 (en) 2005-10-06 2005-11-16 Novartis Ag Organic compounds
US7928113B2 (en) 2005-11-14 2011-04-19 University Of Southern California Integrin-binding small molecules
WO2007069635A1 (ja) 2005-12-13 2007-06-21 Daiichi Sankyo Company, Limited Vla-4阻害薬
MY151045A (en) 2006-02-27 2014-03-31 Elan Pharm Inc Pyrimidinyl sulfonamide compounds which inhibit leukocyte adhesion mediated by vla-4
MY159375A (en) 2006-03-21 2016-12-30 Genentech Inc Combinatorial therapy
EP2021373A4 (en) 2006-05-31 2010-06-02 Hanwa Chemical Corp MONOCLONAL ANTIBODY VCAM-1 SPECIFIC
JP2009541018A (ja) * 2006-06-23 2009-11-26 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 薬剤投与システム
CA2658612C (en) 2006-08-03 2015-11-17 Astrazeneca Ab Antibodies directed to .alpha.v.beta.6 and uses thereof
EP2125076B1 (en) * 2007-02-26 2012-06-20 Duocure, Inc. Spray administration of compositions including active agents such as peptides to the gastrointestinal tract
EP2380564B1 (en) * 2007-04-04 2014-10-22 Sigmoid Pharma Limited An oral pharmaceutical composition
KR101559596B1 (ko) 2007-07-17 2015-10-12 메르크 파텐트 게엠베하 조작 항-알파 v-인테그린 잡종 항체
WO2009076434A1 (en) 2007-12-12 2009-06-18 Molecular Insight Pharmaceuticals, Inc. Inhibitors of integrin vla-4
WO2011004395A1 (en) 2009-07-06 2011-01-13 Intas Biopharmaceuticals Limited Microemulsion formulation for biologicals
JP6030956B2 (ja) * 2009-08-05 2016-11-24 テル ハショマー メディカル リサーチ インフラストラクチャー アンド サーヴィシーズ リミテッド 胃腸管の異常の診断に使える情報を提供する方法と機器
EP2491057A4 (en) 2009-10-23 2013-05-29 Hanwha Chemical Corp HUMAN RECOMBINANT MONOCLONAL ANTIBODY WITH SPECIFIC BINDING TO VCAM-1 AND INHIBITION OF ADHESION AND TRANSMIGRATION BETWEEN LEUKOYZTS AND ENDOTHELIAL CELLS
ITFI20100019A1 (it) 2010-02-12 2011-08-13 Univ Firenze Inibitori peptidomimetici di integrine basati sull'1,2,3-triazolo per la diagnosi e terapia dei tumori.
US8853149B2 (en) 2010-03-19 2014-10-07 H. Lee Moffitt Cancer Center And Research Institute, Inc. Integrin interaction inhibitors for the treatment of cancer
EP2563405A1 (en) 2010-04-30 2013-03-06 Elan Pharmaceuticals Inc. Selective integrin inhibitors
US9415004B2 (en) * 2010-12-23 2016-08-16 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8907081B2 (en) 2011-05-27 2014-12-09 Sharp Laboratories Of America, Inc. Long wavelength absorbing porphyrin photosensitizers for dye-sensitized solar cells
RU2597425C2 (ru) 2011-08-17 2016-09-10 Пирамаль Имэджинг Са Соединения для связывания со специфическим для тромбоцитов гликопротеином iib/iiia и их применение для визуализации тромбов
FR2979346B1 (fr) 2011-08-23 2013-09-27 Univ Joseph Fourier Nanocorps anti-vcam-1
WO2013113326A1 (en) 2012-01-31 2013-08-08 Curevac Gmbh Pharmaceutical composition comprising a polymeric carrier cargo complex and at least one protein or peptide antigen
FR2986432B1 (fr) 2012-02-06 2014-03-14 Univ Lille Ii Droit & Sante Proteines 28kda gst provenant de schistosomes pour leur utilisation dans le traitement des maladies inflammatoires auto-immunes engendrant une reponse de type th1 et/ou th17
GB201207155D0 (en) 2012-04-24 2012-06-06 Isis Innovation Antibodies
US20140349944A1 (en) 2013-05-23 2014-11-27 Musc Foundation For Research Development Chaperone-based integrin inhibitors for the treatment of cancer and inflammatory diseases
RU2015155552A (ru) 2013-05-24 2017-06-27 Нестек С.А. Путеспецифические способы прогнозирования диагноза синдрома раздраженного кишечника
US10472376B2 (en) * 2013-07-03 2019-11-12 Takeda Pharmaceutical Company Limited Amide compound
WO2015059569A1 (en) * 2013-09-26 2015-04-30 Medimetrics Personalized Drug Delivery, B.V. Delivery capsule with threshold release
US20160249793A1 (en) * 2013-12-27 2016-09-01 Kang-Huai Wang Capsule Camera Device with Multi-Spectral Light Sources
ES2923641T3 (es) 2013-12-30 2022-09-29 Epimab Biotherapeutics Inc Inmunoglobulina con Fabs en tándem y usos de la misma
GB201400442D0 (en) * 2014-01-10 2014-02-26 Sigmoid Pharma Ltd Compositions for use in the treatment of ulcerative colitis
US10219748B2 (en) 2014-01-22 2019-03-05 Nutech Ventures Gastrointestinal sensor implantation system
WO2015131078A1 (en) * 2014-02-27 2015-09-03 Biogen Ma Inc. Method of assessing risk of pml
DE102014004843A1 (de) 2014-04-02 2015-10-08 Schaltbau Gmbh Gleichstromschütz mit zusätzlicher Schalttauglichkeit für Wechselstromlasten und Polung entgegen der Vorzugsstromrichtung
CA2955666A1 (en) 2014-08-13 2016-02-18 Cedars-Sinai Medical Center Anti-methanogenic compositions and uses thereof
AU2015319850B2 (en) * 2014-09-25 2019-09-26 Bt Bidco, Inc. Electromechanical pill device with localization capabilities
US9714288B2 (en) 2014-09-30 2017-07-25 The Regents Of The University Of California Antisense compounds and uses thereof
WO2016099792A1 (en) * 2014-11-19 2016-06-23 Nano Pharmaceutical Laboratories Llc Wireless communications system integrating electronics into orally ingestible products for controlled release of active ingredients
CN104473611B (zh) 2015-01-19 2018-01-30 吉林大学 具有超声波定位功能的胶囊内窥镜系统
KR20170122776A (ko) 2015-03-06 2017-11-06 신세틱 바이오로직스, 인코퍼레이티드 마이크로바이옴 보호를 위한 안전하고 유효한 베타-락타마제 투약
WO2023091991A1 (en) 2021-11-17 2023-05-25 H2 Clipper, Inc. Improved system, method and apparatus for airship manufacture using robotics

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