JP2020501508A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020501508A5 JP2020501508A5 JP2019513820A JP2019513820A JP2020501508A5 JP 2020501508 A5 JP2020501508 A5 JP 2020501508A5 JP 2019513820 A JP2019513820 A JP 2019513820A JP 2019513820 A JP2019513820 A JP 2019513820A JP 2020501508 A5 JP2020501508 A5 JP 2020501508A5
- Authority
- JP
- Japan
- Prior art keywords
- multimer
- octamer
- tetramer
- antibody
- domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022183407A JP2023015311A (ja) | 2016-09-15 | 2022-11-16 | 多量体、四量体および八量体 |
| JP2024209457A JP2025029067A (ja) | 2016-09-15 | 2024-12-02 | 多量体、四量体および八量体 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1615768.7 | 2016-09-15 | ||
| GBGB1615768.7A GB201615768D0 (en) | 2016-09-15 | 2016-09-15 | Multivalent soluble TCR |
| GB1713342.2 | 2017-08-20 | ||
| GBGB1713342.2A GB201713342D0 (en) | 2017-08-20 | 2017-08-20 | Multimers & tetramers |
| GB1713351.3 | 2017-08-21 | ||
| GBGB1713351.3A GB201713351D0 (en) | 2017-08-21 | 2017-08-21 | Multimers & tetramers |
| PCT/EP2017/073527 WO2018050902A2 (en) | 2016-09-15 | 2017-09-18 | Multimers, tetramers & octamers |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022183407A Division JP2023015311A (ja) | 2016-09-15 | 2022-11-16 | 多量体、四量体および八量体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020501508A JP2020501508A (ja) | 2020-01-23 |
| JP2020501508A5 true JP2020501508A5 (enExample) | 2020-11-05 |
Family
ID=60022050
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019513820A Pending JP2020501508A (ja) | 2016-09-15 | 2017-09-18 | 多量体、四量体および八量体 |
| JP2022183407A Pending JP2023015311A (ja) | 2016-09-15 | 2022-11-16 | 多量体、四量体および八量体 |
| JP2024209457A Pending JP2025029067A (ja) | 2016-09-15 | 2024-12-02 | 多量体、四量体および八量体 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022183407A Pending JP2023015311A (ja) | 2016-09-15 | 2022-11-16 | 多量体、四量体および八量体 |
| JP2024209457A Pending JP2025029067A (ja) | 2016-09-15 | 2024-12-02 | 多量体、四量体および八量体 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US11453726B2 (enExample) |
| EP (1) | EP3512875A2 (enExample) |
| JP (3) | JP2020501508A (enExample) |
| WO (1) | WO2018050902A2 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020501508A (ja) * | 2016-09-15 | 2020-01-23 | クアドルセプト バイオ リミテッド | 多量体、四量体および八量体 |
| JP7165717B2 (ja) | 2017-03-15 | 2022-11-04 | パンディオン・オペレーションズ・インコーポレイテッド | 標的免疫寛容 |
| AU2018273914A1 (en) | 2017-05-24 | 2019-11-14 | Pandion Operations, Inc. | Targeted immunotolerance |
| PT3428194T (pt) | 2017-07-14 | 2021-11-18 | Immatics Biotechnologies Gmbh | Molécula de polipéptido com especificidade dupla melhorada |
| US10946068B2 (en) | 2017-12-06 | 2021-03-16 | Pandion Operations, Inc. | IL-2 muteins and uses thereof |
| USRE50550E1 (en) | 2017-12-06 | 2025-08-26 | Pandion Operations, Inc. | IL-2 muteins and uses thereof |
| US10174091B1 (en) | 2017-12-06 | 2019-01-08 | Pandion Therapeutics, Inc. | IL-2 muteins |
| WO2020018715A1 (en) * | 2018-07-17 | 2020-01-23 | Massachusetts Institute Of Technology | Soluble multimeric immunoglobulin-scaffold based fusion proteins and uses thereof |
| GB201903767D0 (en) * | 2019-03-19 | 2019-05-01 | Quadrucept Bio Ltd | Multimers, tetramers & octamers |
| CA3141327A1 (en) | 2019-05-20 | 2020-11-26 | Pandion Operations, Inc. | Madcam targeted immunotolerance |
| WO2021168079A1 (en) | 2020-02-21 | 2021-08-26 | Pandion Operations, Inc. | Tissue targeted immunotolerance with a cd39 effector |
| JP2023518312A (ja) * | 2020-03-22 | 2023-04-28 | クアドルセプト バイオ リミテッド | ウイルス株の進化のための多量体 |
| WO2021190980A1 (en) * | 2020-03-22 | 2021-09-30 | Quadrucept Bio Limited | Multimers for viral strain evolution |
| BR112023022765A2 (pt) | 2021-05-05 | 2024-01-02 | Immatics Biotechnologies Gmbh | Proteínas de ligação ao antígeno que ligam especificamente o prame |
| GEAP202416581A (en) * | 2022-01-13 | 2024-12-10 | Ingenia Therapeutics Inc | Vegf and tie2-binding fusion protein and uses thereof |
| GB202216503D0 (en) | 2022-11-05 | 2022-12-21 | Quadrucept Bio Ltd | Non-human vertebrates & cells |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| GB9416721D0 (en) | 1994-08-18 | 1994-10-12 | Short Brothers Plc | A bias yarn assembly forming device |
| ATE274064T1 (de) * | 1995-05-23 | 2004-09-15 | Morphosys Ag | Multimere proteine |
| ATE219517T1 (de) | 1995-08-18 | 2002-07-15 | Morphosys Ag | Protein-/(poly)peptidbibliotheken |
| HU230048B1 (hu) * | 1996-02-09 | 2015-06-29 | Abbvie Biotechnology Ltd | Humán TNFalfa-kötő antitestek alkalmazása |
| DE19742706B4 (de) | 1997-09-26 | 2013-07-25 | Pieris Proteolab Ag | Lipocalinmuteine |
| IL127127A0 (en) | 1998-11-18 | 1999-09-22 | Peptor Ltd | Small functional units of antibody heavy chain variable regions |
| US7115396B2 (en) | 1998-12-10 | 2006-10-03 | Compound Therapeutics, Inc. | Protein scaffolds for antibody mimics and other binding proteins |
| US6818418B1 (en) | 1998-12-10 | 2004-11-16 | Compound Therapeutics, Inc. | Protein scaffolds for antibody mimics and other binding proteins |
| JP5291279B2 (ja) | 2000-09-08 | 2013-09-18 | ウニヴェルジテート・チューリッヒ | 反復モジュールを含む反復タンパク質の集合体 |
| CA2457636C (en) | 2001-08-10 | 2012-01-03 | Aberdeen University | Antigen binding domains |
| EP1567553A2 (en) * | 2002-12-03 | 2005-08-31 | Avidex Ltd. | Complexes of receptors |
| EP1641818B1 (en) | 2003-07-04 | 2008-12-03 | Affibody AB | Polypeptides having binding affinity for her2 |
| WO2005019255A1 (en) | 2003-08-25 | 2005-03-03 | Pieris Proteolab Ag | Muteins of tear lipocalin |
| WO2005056764A2 (en) | 2003-12-05 | 2005-06-23 | Compound Therapeutics, Inc. | Inhibitors of type 2 vascular endothelial growth factor receptors |
| JP4773434B2 (ja) | 2004-05-19 | 2011-09-14 | イムノコア リミテッド | 高親和性ｎｙ−ｅｓｏｔ細胞受容体 |
| JP5364870B2 (ja) | 2005-08-19 | 2013-12-11 | アッヴィ・インコーポレイテッド | 二重可変ドメイン免疫グロブリン及びその使用 |
| EP1958957A1 (en) | 2007-02-16 | 2008-08-20 | NascaCell Technologies AG | Polypeptide comprising a knottin protein moiety |
| WO2010142551A2 (en) | 2009-06-12 | 2010-12-16 | Ablynx N.V. | Single variable domain (vhh) antibodies to cytokines of the il-17 receptor family |
| GB0911566D0 (en) * | 2009-07-03 | 2009-08-12 | Immunocore Ltd | T cell receptors |
| NZ587657A (en) | 2009-09-24 | 2011-12-22 | Sprywat Pty Ltd | A garden design method where a partial preview of an electronic garden template is provided to the customer |
| US20150139991A1 (en) * | 2010-10-15 | 2015-05-21 | Leadartis, S.L. | Generation of multifunctional and multivalent polypeptide complexes with collagen xviii trimerization domain |
| CN102924600B (zh) * | 2012-11-14 | 2013-10-30 | 河南大学 | 死亡受体5激动性多价抗体及其在制备抗肿瘤药物中的应用 |
| ES3040431T3 (en) | 2014-03-12 | 2025-10-31 | Yeda Res & Dev | Reducing systemic regulatory t cell levels or activity for treatment of disease and injury of the cns |
| MX2018008308A (es) | 2016-01-11 | 2019-05-15 | Inhibrx Inc | Proteinas de fusion de union a 41bb multivalentes y multiespecificas. |
| JP2020501508A (ja) * | 2016-09-15 | 2020-01-23 | クアドルセプト バイオ リミテッド | 多量体、四量体および八量体 |
| GB201903767D0 (en) | 2019-03-19 | 2019-05-01 | Quadrucept Bio Ltd | Multimers, tetramers & octamers |
-
2017
- 2017-09-18 JP JP2019513820A patent/JP2020501508A/ja active Pending
- 2017-09-18 US US16/333,583 patent/US11453726B2/en active Active
- 2017-09-18 EP EP17780319.4A patent/EP3512875A2/en active Pending
- 2017-09-18 WO PCT/EP2017/073527 patent/WO2018050902A2/en not_active Ceased
-
2022
- 2022-11-16 JP JP2022183407A patent/JP2023015311A/ja active Pending
-
2024
- 2024-12-02 JP JP2024209457A patent/JP2025029067A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2015295239B2 (en) | Antibody constructs for CDH19 and CD3 | |
| IL278014B1 (en) | Anti-myostatin antibodies, polypeptides containing variable fc regions and methods of use | |
| EP3345919B1 (en) | Binding domains directed against gpcr: g protein complexes and uses derived thereof | |
| RU2022102624A (ru) | Композиции и способы для соединения внеклеточных доменов типа i и типа ii в качестве гетерологичных химерных белков | |
| TW201325612A (zh) | 三倍體Ｆｃ融合蛋白及其用途 | |
| CN119505009A (zh) | 针对cldn18.2和cd3的抗体构建体 | |
| JP2018064568A5 (enExample) | ||
| JP2017512063A5 (enExample) | ||
| JP2018529363A5 (enExample) | ||
| JP2019521643A5 (enExample) | ||
| CN106459187A (zh) | 用于抗葡萄球菌剂的吞噬细胞递送的组合物和方法 | |
| JP2019524100A5 (enExample) | ||
| JP2019506841A5 (enExample) | ||
| JP2017522903A5 (enExample) | ||
| JP2019508444A5 (enExample) | ||
| HRP20210635T1 (hr) | Novi mutant humanog seruma albumina | |
| JP2013545455A5 (enExample) | ||
| JP2019514361A5 (enExample) | ||
| JP2020532285A5 (enExample) | ||
| HRP20221142T1 (hr) | Modificirana igg protutijela koja se vežu na transformirajući faktor rasta beta1 s visokim afinitetom, avidnošću i specifičnošću | |
| JP2019504617A5 (enExample) | ||
| US11773177B2 (en) | Variant antibodies that bind OX40 | |
| JP2018512124A5 (enExample) | ||
| JP2016523910A5 (enExample) | ||
| KR20160138580A (ko) | Wisp1에 결합하는 항원 결합 단백질 |