JP2020501508A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020501508A5 JP2020501508A5 JP2019513820A JP2019513820A JP2020501508A5 JP 2020501508 A5 JP2020501508 A5 JP 2020501508A5 JP 2019513820 A JP2019513820 A JP 2019513820A JP 2019513820 A JP2019513820 A JP 2019513820A JP 2020501508 A5 JP2020501508 A5 JP 2020501508A5
- Authority
- JP
- Japan
- Prior art keywords
- multimer
- octamer
- tetramer
- antibody
- domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022183407A JP2023015311A (ja) | 2016-09-15 | 2022-11-16 | 多量体、四量体および八量体 |
| JP2024209457A JP2025029067A (ja) | 2016-09-15 | 2024-12-02 | 多量体、四量体および八量体 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1615768.7 | 2016-09-15 | ||
| GBGB1615768.7A GB201615768D0 (en) | 2016-09-15 | 2016-09-15 | Multivalent soluble TCR |
| GBGB1713342.2A GB201713342D0 (en) | 2017-08-20 | 2017-08-20 | Multimers & tetramers |
| GB1713342.2 | 2017-08-20 | ||
| GBGB1713351.3A GB201713351D0 (en) | 2017-08-21 | 2017-08-21 | Multimers & tetramers |
| GB1713351.3 | 2017-08-21 | ||
| PCT/EP2017/073527 WO2018050902A2 (en) | 2016-09-15 | 2017-09-18 | Multimers, tetramers & octamers |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022183407A Division JP2023015311A (ja) | 2016-09-15 | 2022-11-16 | 多量体、四量体および八量体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020501508A JP2020501508A (ja) | 2020-01-23 |
| JP2020501508A5 true JP2020501508A5 (enExample) | 2020-11-05 |
Family
ID=60022050
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019513820A Pending JP2020501508A (ja) | 2016-09-15 | 2017-09-18 | 多量体、四量体および八量体 |
| JP2022183407A Pending JP2023015311A (ja) | 2016-09-15 | 2022-11-16 | 多量体、四量体および八量体 |
| JP2024209457A Pending JP2025029067A (ja) | 2016-09-15 | 2024-12-02 | 多量体、四量体および八量体 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022183407A Pending JP2023015311A (ja) | 2016-09-15 | 2022-11-16 | 多量体、四量体および八量体 |
| JP2024209457A Pending JP2025029067A (ja) | 2016-09-15 | 2024-12-02 | 多量体、四量体および八量体 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US11453726B2 (enExample) |
| EP (1) | EP3512875A2 (enExample) |
| JP (3) | JP2020501508A (enExample) |
| WO (1) | WO2018050902A2 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020501508A (ja) * | 2016-09-15 | 2020-01-23 | クアドルセプト バイオ リミテッド | 多量体、四量体および八量体 |
| BR112019018915A2 (pt) | 2017-03-15 | 2020-04-14 | Pandion Therapeutics Inc | imunotolerância direcionada |
| AU2018273914A1 (en) | 2017-05-24 | 2019-11-14 | Pandion Operations, Inc. | Targeted immunotolerance |
| US20190016802A1 (en) | 2017-07-14 | 2019-01-17 | Immatics Biotechnologies Gmbh | Dual specificity polypeptide molecule |
| US10946068B2 (en) | 2017-12-06 | 2021-03-16 | Pandion Operations, Inc. | IL-2 muteins and uses thereof |
| USRE50550E1 (en) | 2017-12-06 | 2025-08-26 | Pandion Operations, Inc. | IL-2 muteins and uses thereof |
| US10174091B1 (en) | 2017-12-06 | 2019-01-08 | Pandion Therapeutics, Inc. | IL-2 muteins |
| WO2020018715A1 (en) * | 2018-07-17 | 2020-01-23 | Massachusetts Institute Of Technology | Soluble multimeric immunoglobulin-scaffold based fusion proteins and uses thereof |
| GB201903767D0 (en) * | 2019-03-19 | 2019-05-01 | Quadrucept Bio Ltd | Multimers, tetramers & octamers |
| AU2020279240A1 (en) | 2019-05-20 | 2021-12-23 | Pandion Operations, Inc. | MAdCAM targeted immunotolerance |
| US11981715B2 (en) | 2020-02-21 | 2024-05-14 | Pandion Operations, Inc. | Tissue targeted immunotolerance with a CD39 effector |
| WO2021190980A1 (en) * | 2020-03-22 | 2021-09-30 | Quadrucept Bio Limited | Multimers for viral strain evolution |
| CN116096743A (zh) * | 2020-03-22 | 2023-05-09 | 科德路赛普特生物有限公司 | 用于病毒株进化的多聚体 |
| WO2022233956A1 (en) | 2021-05-05 | 2022-11-10 | Immatics Biotechnologies Gmbh | Antigen binding proteins specifically binding prame |
| AU2023206363A1 (en) * | 2022-01-13 | 2024-08-15 | Ingenia Therapeutics Inc. | Vegf and tie2-binding fusion protein and uses thereof |
| GB202216503D0 (en) | 2022-11-05 | 2022-12-21 | Quadrucept Bio Ltd | Non-human vertebrates & cells |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| GB9416721D0 (en) | 1994-08-18 | 1994-10-12 | Short Brothers Plc | A bias yarn assembly forming device |
| WO1996037621A2 (en) * | 1995-05-23 | 1996-11-28 | Morphosys Gesellschaft Für Proteinoptimierung Mbh | Multimeric proteins |
| EP0859841B1 (en) | 1995-08-18 | 2002-06-19 | MorphoSys AG | Protein/(poly)peptide libraries |
| ATE239041T1 (de) * | 1996-02-09 | 2003-05-15 | Basf Ag | Humane antikörper welche an humanen tnfalpha binden |
| DE19742706B4 (de) | 1997-09-26 | 2013-07-25 | Pieris Proteolab Ag | Lipocalinmuteine |
| IL127127A0 (en) | 1998-11-18 | 1999-09-22 | Peptor Ltd | Small functional units of antibody heavy chain variable regions |
| US7115396B2 (en) | 1998-12-10 | 2006-10-03 | Compound Therapeutics, Inc. | Protein scaffolds for antibody mimics and other binding proteins |
| US6818418B1 (en) | 1998-12-10 | 2004-11-16 | Compound Therapeutics, Inc. | Protein scaffolds for antibody mimics and other binding proteins |
| EP1332209B1 (en) | 2000-09-08 | 2009-11-11 | Universität Zürich | Collections of repeat proteins comprising repeat modules |
| AU2002319544B2 (en) | 2001-08-10 | 2008-07-10 | Aberdeen University | Antigen binding domains from fish |
| JP2006523437A (ja) * | 2002-12-03 | 2006-10-19 | アヴィデックス リミテッド | レセプター複合体 |
| CA2531238C (en) | 2003-07-04 | 2015-02-24 | Affibody Ab | Polypeptides having binding affinity for her2 |
| WO2005019255A1 (en) | 2003-08-25 | 2005-03-03 | Pieris Proteolab Ag | Muteins of tear lipocalin |
| BRPI0417302A (pt) | 2003-12-05 | 2007-03-06 | Compound Therapeutics Inc | inibidores de receptores de fator de crescimento endotelial vascular do tipo 2 |
| WO2005113595A2 (en) | 2004-05-19 | 2005-12-01 | Avidex Ltd | High affinity ny-eso t cell receptor |
| KR20140053410A (ko) | 2005-08-19 | 2014-05-07 | 아보트 러보러터리즈 | 이원 가변 도메인 면역글로불린 및 이의 용도 |
| EP1958957A1 (en) | 2007-02-16 | 2008-08-20 | NascaCell Technologies AG | Polypeptide comprising a knottin protein moiety |
| WO2010142551A2 (en) | 2009-06-12 | 2010-12-16 | Ablynx N.V. | Single variable domain (vhh) antibodies to cytokines of the il-17 receptor family |
| GB0911566D0 (en) * | 2009-07-03 | 2009-08-12 | Immunocore Ltd | T cell receptors |
| AU2010101514A4 (en) | 2009-09-24 | 2014-06-26 | Sprywat Pty Ltd | A Garden Design Method |
| ES2701445T3 (es) * | 2010-10-15 | 2019-02-22 | Leadartis S L | Generación de complejos polipeptídicos multifuncionales y multivalentes mediante el dominio de trimerización del colágeno XVIII |
| CN102924600B (zh) * | 2012-11-14 | 2013-10-30 | 河南大学 | 死亡受体5激动性多价抗体及其在制备抗肿瘤药物中的应用 |
| KR20200029627A (ko) | 2014-03-12 | 2020-03-18 | 예다 리서치 앤드 디벨럽먼트 캄파니 리미티드 | Cns의 질환 및 손상을 치료하기 위한 전신적 조절 t 세포 수준 또는 활성의 감소 |
| IL304871A (en) | 2016-01-11 | 2023-10-01 | Inhibrx Inc | Multispecific and multivalent binding fusion proteins - 41BB, preparations containing them and their uses |
| JP2020501508A (ja) * | 2016-09-15 | 2020-01-23 | クアドルセプト バイオ リミテッド | 多量体、四量体および八量体 |
| GB201903767D0 (en) | 2019-03-19 | 2019-05-01 | Quadrucept Bio Ltd | Multimers, tetramers & octamers |
-
2017
- 2017-09-18 JP JP2019513820A patent/JP2020501508A/ja active Pending
- 2017-09-18 WO PCT/EP2017/073527 patent/WO2018050902A2/en not_active Ceased
- 2017-09-18 US US16/333,583 patent/US11453726B2/en active Active
- 2017-09-18 EP EP17780319.4A patent/EP3512875A2/en active Pending
-
2022
- 2022-11-16 JP JP2022183407A patent/JP2023015311A/ja active Pending
-
2024
- 2024-12-02 JP JP2024209457A patent/JP2025029067A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2015295239B2 (en) | Antibody constructs for CDH19 and CD3 | |
| IL278014B1 (en) | Anti-myostatin antibodies, polypeptides containing variable fc regions and methods of use | |
| EP3345919B1 (en) | Binding domains directed against gpcr: g protein complexes and uses derived thereof | |
| RU2022102624A (ru) | Композиции и способы для соединения внеклеточных доменов типа i и типа ii в качестве гетерологичных химерных белков | |
| TW201325612A (zh) | 三倍體Ｆｃ融合蛋白及其用途 | |
| CN119505009A (zh) | 针对cldn18.2和cd3的抗体构建体 | |
| JP2018064568A5 (enExample) | ||
| JP2017512063A5 (enExample) | ||
| JP2019524100A5 (enExample) | ||
| JP2019521643A5 (enExample) | ||
| JP2018529363A5 (enExample) | ||
| CN106459187A (zh) | 用于抗葡萄球菌剂的吞噬细胞递送的组合物和方法 | |
| JP2019506841A5 (enExample) | ||
| JP2017522903A5 (enExample) | ||
| JP2019508444A5 (enExample) | ||
| HRP20210635T1 (hr) | Novi mutant humanog seruma albumina | |
| JP2013545455A5 (enExample) | ||
| JP2019514361A5 (enExample) | ||
| JP2020532285A5 (enExample) | ||
| HRP20221142T1 (hr) | Modificirana igg protutijela koja se vežu na transformirajući faktor rasta beta1 s visokim afinitetom, avidnošću i specifičnošću | |
| JP2019504617A5 (enExample) | ||
| US11773177B2 (en) | Variant antibodies that bind OX40 | |
| JP2018512124A5 (enExample) | ||
| JP2016523910A5 (enExample) | ||
| KR20160138580A (ko) | Wisp1에 결합하는 항원 결합 단백질 |