JP2020500882A5 - - Google Patents
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- Publication number
- JP2020500882A5 JP2020500882A5 JP2019529890A JP2019529890A JP2020500882A5 JP 2020500882 A5 JP2020500882 A5 JP 2020500882A5 JP 2019529890 A JP2019529890 A JP 2019529890A JP 2019529890 A JP2019529890 A JP 2019529890A JP 2020500882 A5 JP2020500882 A5 JP 2020500882A5
- Authority
- JP
- Japan
- Prior art keywords
- drug
- transdermal patch
- treprostinil
- patch
- adhesive layer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 claims 17
- 229940079593 drug Drugs 0.000 claims 15
- PAJMKGZZBBTTOY-ZFORQUDYSA-N treprostinil Chemical compound C1=CC=C(OCC(O)=O)C2=C1C[C@@H]1[C@@H](CC[C@@H](O)CCCCC)[C@H](O)C[C@@H]1C2 PAJMKGZZBBTTOY-ZFORQUDYSA-N 0.000 claims 10
- 229960005032 treprostinil Drugs 0.000 claims 10
- 239000010410 layer Substances 0.000 claims 8
- 229920000642 polymer Polymers 0.000 claims 7
- 239000011159 matrix material Substances 0.000 claims 6
- 150000003839 salts Chemical class 0.000 claims 6
- 239000012790 adhesive layer Substances 0.000 claims 5
- 239000004820 Pressure-sensitive adhesive Substances 0.000 claims 4
- 239000000126 substance Substances 0.000 claims 3
- 206010019280 Heart failures Diseases 0.000 claims 2
- 206010040943 Skin Ulcer Diseases 0.000 claims 2
- 230000007654 ischemic lesion Effects 0.000 claims 2
- 239000007788 liquid Substances 0.000 claims 2
- 239000012528 membrane Substances 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 229940124597 therapeutic agent Drugs 0.000 claims 2
- 201000001320 Atherosclerosis Diseases 0.000 claims 1
- 206010007559 Cardiac failure congestive Diseases 0.000 claims 1
- 208000024172 Cardiovascular disease Diseases 0.000 claims 1
- 239000004821 Contact adhesive Substances 0.000 claims 1
- 208000003790 Foot Ulcer Diseases 0.000 claims 1
- 206010020772 Hypertension Diseases 0.000 claims 1
- 208000035901 Ischaemic ulcer Diseases 0.000 claims 1
- 208000019693 Lung disease Diseases 0.000 claims 1
- 208000018262 Peripheral vascular disease Diseases 0.000 claims 1
- 206010064911 Pulmonary arterial hypertension Diseases 0.000 claims 1
- 208000001647 Renal Insufficiency Diseases 0.000 claims 1
- 208000034841 Thrombotic Microangiopathies Diseases 0.000 claims 1
- 206010058990 Venous occlusion Diseases 0.000 claims 1
- 239000008186 active pharmaceutical agent Substances 0.000 claims 1
- 239000000853 adhesive Substances 0.000 claims 1
- 230000001070 adhesive effect Effects 0.000 claims 1
- 230000000202 analgesic effect Effects 0.000 claims 1
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 1
- 239000002260 anti-inflammatory agent Substances 0.000 claims 1
- 239000003146 anticoagulant agent Substances 0.000 claims 1
- 229940127219 anticoagulant drug Drugs 0.000 claims 1
- 208000006673 asthma Diseases 0.000 claims 1
- 230000036523 atherogenesis Effects 0.000 claims 1
- 150000001735 carboxylic acids Chemical group 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 229940088679 drug related substance Drugs 0.000 claims 1
- 239000003623 enhancer Substances 0.000 claims 1
- 208000027866 inflammatory disease Diseases 0.000 claims 1
- 208000023589 ischemic disease Diseases 0.000 claims 1
- 230000000302 ischemic effect Effects 0.000 claims 1
- 201000006370 kidney failure Diseases 0.000 claims 1
- 208000030175 lameness Diseases 0.000 claims 1
- 239000010985 leather Substances 0.000 claims 1
- 239000003589 local anesthetic agent Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 201000001119 neuropathy Diseases 0.000 claims 1
- 230000007823 neuropathy Effects 0.000 claims 1
- 230000007310 pathophysiology Effects 0.000 claims 1
- 230000035515 penetration Effects 0.000 claims 1
- 230000002093 peripheral effect Effects 0.000 claims 1
- 208000033808 peripheral neuropathy Diseases 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 239000002861 polymer material Substances 0.000 claims 1
- 230000002062 proliferating effect Effects 0.000 claims 1
- 208000005069 pulmonary fibrosis Diseases 0.000 claims 1
- 208000002815 pulmonary hypertension Diseases 0.000 claims 1
- 230000008085 renal dysfunction Effects 0.000 claims 1
- 230000001568 sexual effect Effects 0.000 claims 1
- 239000002356 single layer Substances 0.000 claims 1
- 231100000245 skin permeability Toxicity 0.000 claims 1
- 231100000019 skin ulcer Toxicity 0.000 claims 1
- 239000012453 solvate Substances 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
- 239000005526 vasoconstrictor agent Substances 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023114183A JP2023134620A (ja) | 2016-12-05 | 2023-07-12 | トレプロスチニルおよびその塩の皮膚投与および経皮投与方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662430053P | 2016-12-05 | 2016-12-05 | |
| US62/430,053 | 2016-12-05 | ||
| PCT/US2017/064612 WO2018106632A1 (en) | 2016-12-05 | 2017-12-05 | Dermal and transdermal administration of treprostinil and salts thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023114183A Division JP2023134620A (ja) | 2016-12-05 | 2023-07-12 | トレプロスチニルおよびその塩の皮膚投与および経皮投与方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020500882A JP2020500882A (ja) | 2020-01-16 |
| JP2020500882A5 true JP2020500882A5 (enExample) | 2021-01-07 |
Family
ID=60782377
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019529890A Pending JP2020500882A (ja) | 2016-12-05 | 2017-12-05 | トレプロスチニルおよびその塩の皮膚投与および経皮投与方法 |
| JP2023114183A Pending JP2023134620A (ja) | 2016-12-05 | 2023-07-12 | トレプロスチニルおよびその塩の皮膚投与および経皮投与方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023114183A Pending JP2023134620A (ja) | 2016-12-05 | 2023-07-12 | トレプロスチニルおよびその塩の皮膚投与および経皮投与方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20190290597A1 (enExample) |
| EP (1) | EP3548010A1 (enExample) |
| JP (2) | JP2020500882A (enExample) |
| KR (2) | KR20230119035A (enExample) |
| CN (1) | CN110381930A (enExample) |
| CA (1) | CA3045917A1 (enExample) |
| IL (1) | IL267046A (enExample) |
| WO (1) | WO2018106632A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6542128B2 (ja) | 2013-01-11 | 2019-07-10 | コルセア ファーマ インコーポレイテッド | トレプロスチニルのプロドラッグ |
| US9505737B2 (en) | 2013-01-11 | 2016-11-29 | Corsair Pharma, Inc. | Treprostinil derivative compounds and methods of using same |
| US11607026B2 (en) * | 2014-05-30 | 2023-03-21 | Johnson & Johnson Consumer Inc. | Device for delivery of skin care composition |
| US9394227B1 (en) | 2015-06-17 | 2016-07-19 | Corsair Pharma, Inc. | Treprostinil derivatives and compositions and uses thereof |
| US9643911B2 (en) | 2015-06-17 | 2017-05-09 | Corsair Pharma, Inc. | Treprostinil derivatives and compositions and uses thereof |
| WO2019218006A1 (en) * | 2018-05-14 | 2019-11-21 | Butterworth Building | Oil therapy method and device |
| AU2019344541B2 (en) * | 2018-09-18 | 2022-01-06 | Eli Lilly And Company | Erbumine salt of treprostinil |
| US20230293352A1 (en) * | 2020-08-16 | 2023-09-21 | Ofer Spottheim | Medical dressing |
| JP2024094445A (ja) * | 2021-03-17 | 2024-07-10 | 国立大学法人九州大学 | 経皮吸収剤 |
| EP4313007A4 (en) * | 2021-03-31 | 2025-03-12 | Lyfe CHNG, LLC | TRANSDERMAL SYSTEM, FORMULATION AND METHOD FOR THERAPEUTIC ADMINISTRATION OF A PSYCHEDELIC AGENT |
| CN113842377A (zh) * | 2021-08-11 | 2021-12-28 | 杭州师范大学 | 一种经皮递送榄香烯的pdms微针贴片及其制备方法 |
| US20250017870A1 (en) * | 2021-11-15 | 2025-01-16 | Artience Co., Ltd. | Adhesive patch containing selexipag as active ingredient |
| WO2023114755A1 (en) * | 2021-12-13 | 2023-06-22 | WELSH Stephen | Adhesive bandage system for medication delivery and indication of procedure location |
| WO2023144276A1 (en) * | 2022-01-27 | 2023-08-03 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system for the transdermal administration of selexipag |
| JP2025515512A (ja) * | 2022-04-29 | 2025-05-15 | 兆科薬業（広州）有限公司 | トレプロスチニルソフトミスト吸入剤 |
| WO2024015602A1 (en) * | 2022-07-15 | 2024-01-18 | Aso Llc | Therapeutic foot patch for cough treatment |
| CN118178292B (zh) * | 2024-03-07 | 2024-10-01 | 广州博科化妆品有限公司 | 一种含有水蛭素和植物提取物的防脱洗发露及其制备方法 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3598122A (en) | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
| US4144317A (en) | 1975-05-30 | 1979-03-13 | Alza Corporation | Device consisting of copolymer having acetoxy groups for delivering drugs |
| US4262003A (en) | 1975-12-08 | 1981-04-14 | Alza Corporation | Method and therapeutic system for administering scopolamine transdermally |
| US4201211A (en) | 1977-07-12 | 1980-05-06 | Alza Corporation | Therapeutic system for administering clonidine transdermally |
| US4379454A (en) | 1981-02-17 | 1983-04-12 | Alza Corporation | Dosage for coadministering drug and percutaneous absorption enhancer |
| GB9011588D0 (en) * | 1990-05-24 | 1990-07-11 | Wellcome Found | Prostaglandin analogues for use in medicine |
| US5234690A (en) | 1991-08-23 | 1993-08-10 | Cygnus Therapeutic Systems | Transdermal drug delivery device using an unfilled microporous membrane to achieve delayed onset |
| US5797898A (en) | 1996-07-02 | 1998-08-25 | Massachusetts Institute Of Technology | Microchip drug delivery devices |
| US6682757B1 (en) | 2000-11-16 | 2004-01-27 | Euro-Celtique, S.A. | Titratable dosage transdermal delivery system |
| CA2959852A1 (en) | 2003-05-22 | 2005-01-27 | United Therapeutics Corporation | Compounds and methods for delivery of prostacyclin analogs |
| WO2005009510A2 (en) | 2003-07-23 | 2005-02-03 | The Regents Of The University Of California | Penetration enhancer combinations for transdermal delivery |
| CN101647792B (zh) * | 2003-12-16 | 2012-11-28 | 联合治疗公司 | 曲前列环素在制备治疗和预防缺血性损害的药物中的用途 |
| DE602005020269D1 (de) * | 2004-04-12 | 2010-05-12 | United Therapeutics Corp | Verwendung von treprostinil zur behandlung von neuropathischen diabetischen fussgeschwüren |
| CA3084317C (en) * | 2008-03-31 | 2024-01-09 | Passport Technologies, Inc. | Permeant delivery system and methods for use thereof |
| US8350079B2 (en) | 2008-05-08 | 2013-01-08 | United Therapeutics Corporation | Treprostinil formulation |
| US20110294815A1 (en) | 2008-06-27 | 2011-12-01 | Harbeson Scott L | Prostacyclin analogs |
| US9327105B2 (en) * | 2010-03-26 | 2016-05-03 | Itrace Biomedical Inc. | Active transdermal drug delivery system and the method thereof |
| CN103193627B (zh) | 2012-01-10 | 2016-04-20 | 上海天伟生物制药有限公司 | 一种前列腺素类似物的晶型及其制备方法和用途 |
| CN103193626B (zh) | 2012-01-10 | 2016-05-11 | 上海天伟生物制药有限公司 | 一种前列腺素类似物的晶型及其制备方法和用途 |
| WO2014022376A2 (en) * | 2012-08-01 | 2014-02-06 | United Therapeutics Corporation | Treatment of pulmonary arterial hypertension with prostacyclin-treated endothelial progenitor cells |
| US9505737B2 (en) * | 2013-01-11 | 2016-11-29 | Corsair Pharma, Inc. | Treprostinil derivative compounds and methods of using same |
| JP2016517410A (ja) | 2013-03-14 | 2016-06-16 | ユナイテッド セラピューティクス コーポレイション | トレプロスチニルの固体形態 |
| US9394227B1 (en) * | 2015-06-17 | 2016-07-19 | Corsair Pharma, Inc. | Treprostinil derivatives and compositions and uses thereof |
-
2017
- 2017-12-05 CN CN201780084968.9A patent/CN110381930A/zh active Pending
- 2017-12-05 EP EP17818389.3A patent/EP3548010A1/en active Pending
- 2017-12-05 US US16/465,683 patent/US20190290597A1/en not_active Abandoned
- 2017-12-05 JP JP2019529890A patent/JP2020500882A/ja active Pending
- 2017-12-05 KR KR1020237026190A patent/KR20230119035A/ko not_active Ceased
- 2017-12-05 WO PCT/US2017/064612 patent/WO2018106632A1/en not_active Ceased
- 2017-12-05 CA CA3045917A patent/CA3045917A1/en active Pending
- 2017-12-05 KR KR1020197018666A patent/KR20190109399A/ko not_active Ceased
-
2019
- 2019-06-02 IL IL267046A patent/IL267046A/en unknown
-
2023
- 2023-07-12 JP JP2023114183A patent/JP2023134620A/ja active Pending
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