JP2020500205A5 - - Google Patents

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Publication number
JP2020500205A5
JP2020500205A5 JP2019528114A JP2019528114A JP2020500205A5 JP 2020500205 A5 JP2020500205 A5 JP 2020500205A5 JP 2019528114 A JP2019528114 A JP 2019528114A JP 2019528114 A JP2019528114 A JP 2019528114A JP 2020500205 A5 JP2020500205 A5 JP 2020500205A5
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JP
Japan
Prior art keywords
pharmaceutically acceptable
dione
isoindoline
dioxapiperidin
acceptable salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2019528114A
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English (en)
Japanese (ja)
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JP7143296B2 (ja
JP2020500205A (ja
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Publication date
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Priority claimed from PCT/CN2017/112668 external-priority patent/WO2018095377A1/zh
Publication of JP2020500205A publication Critical patent/JP2020500205A/ja
Publication of JP2020500205A5 publication Critical patent/JP2020500205A5/ja
Application granted granted Critical
Publication of JP7143296B2 publication Critical patent/JP7143296B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2019528114A 2016-11-24 2017-11-23 ピペリジン-2,6-ジオン誘導体及び潰瘍性結腸炎の治療 Active JP7143296B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201611041317 2016-11-24
CN201611041317.5 2016-11-24
PCT/CN2017/112668 WO2018095377A1 (zh) 2016-11-24 2017-11-23 哌啶-2,6-二酮衍生物以及溃疡性结肠炎的治疗

Publications (3)

Publication Number Publication Date
JP2020500205A JP2020500205A (ja) 2020-01-09
JP2020500205A5 true JP2020500205A5 (enExample) 2020-08-20
JP7143296B2 JP7143296B2 (ja) 2022-09-28

Family

ID=62194806

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019528114A Active JP7143296B2 (ja) 2016-11-24 2017-11-23 ピペリジン-2,6-ジオン誘導体及び潰瘍性結腸炎の治療
JP2019528110A Active JP7143295B2 (ja) 2016-11-24 2017-11-23 ピペリジン-2,6-ジオン誘導体及びクローン病の治療

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2019528110A Active JP7143295B2 (ja) 2016-11-24 2017-11-23 ピペリジン-2,6-ジオン誘導体及びクローン病の治療

Country Status (7)

Country Link
US (4) US20220372013A2 (enExample)
EP (2) EP3546450A4 (enExample)
JP (2) JP7143296B2 (enExample)
CN (2) CN108101886A (enExample)
AU (2) AU2017366514B2 (enExample)
CA (2) CA3049161C (enExample)
WO (2) WO2018095378A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220372013A2 (en) 2016-11-24 2022-11-24 Tianjin Hemay Pharmaceutical Sci-Tech Co., Ltd Piperidine-2,6-dione derivatives and crohn's disease treating
CN108727319A (zh) * 2018-09-05 2018-11-02 常州大学 一种3-硝基邻苯二甲酸酐的制备方法
CN109293631B (zh) * 2018-11-30 2020-05-08 常州制药厂有限公司 3-氨基-n-(2,6-二氧代-3-哌啶基)-邻苯二甲酰亚胺化合物的制备方法
GB202002926D0 (en) * 2020-02-28 2020-04-15 Benevolentai Tech Limited Compositions and uses thereof
CN111320604B (zh) * 2020-04-22 2021-02-09 牡丹江医学院 一种治疗小儿口腔黏膜疾病的化合物、制备方法及其用途
CN118370746A (zh) * 2024-04-25 2024-07-23 江苏省中医院 马尿酸在制备溃疡性结肠炎治疗药物中的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2172474B1 (es) 2001-03-01 2004-01-16 Fundacion Universitaria San Pa Derivados de glutarimida como agentes terapeuticos.
EP1336602A1 (en) * 2002-02-13 2003-08-20 Giovanni Scaramuzzino Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases
CN100488959C (zh) * 2003-03-27 2009-05-20 天津和美生物技术有限公司 水溶性的酞胺哌啶酮衍生物
WO2005028436A2 (en) * 2003-09-17 2005-03-31 The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Thalidomide analogs as tnf-alpha modulators
CN101141960A (zh) * 2005-01-25 2008-03-12 细胞基因公司 使用4-氨基-2-(3-甲基-2,6-二氧代哌啶-3-基)-异吲哚-1,3-二酮的方法和组合物
CN100383139C (zh) 2005-04-07 2008-04-23 天津和美生物技术有限公司 可抑制细胞释放肿瘤坏死因子的哌啶-2,6-二酮衍生物
CN1961876A (zh) * 2005-11-08 2007-05-16 北京恩华医药研究院 邻苯二甲酰亚胺衍生物在制备抗新血管生成的药物中的用途
US9193989B2 (en) 2010-06-18 2015-11-24 Taiho Pharmaceutical Co., Ltd. PRPK-TPRKB modulators and uses thereof
EP2981262A1 (en) 2013-04-02 2016-02-10 Celgene Corporation Methods and compositions using 4-amino-2-(2,6-dioxo-piperidine-3-yl)-isoindoline-1,3-dione for treatment and management of central nervous system cancers
US20220372013A2 (en) 2016-11-24 2022-11-24 Tianjin Hemay Pharmaceutical Sci-Tech Co., Ltd Piperidine-2,6-dione derivatives and crohn's disease treating

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